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Digestive Tract
Digestive Tract

Digestion: The mechanical
and chemical breaking down
of food into smaller
components
Digestive Tract
Macromolecules:
Large molecules that
provide nutrition (i.e.
energy)
-Proteins
-Nucleic acids
-Carbohydrates
-Fats
Digestive Tract: A Visual Journey
Modern day technology allows us to see the journey
that food takes through our bodies.
Click on the video below:
Digestive Tract: Mouth, Teeth, Tongue, and Glands
Digestive Tract: Mouth, Teeth, Tongue, and Glands

Tearing

/Cuspid

Grinding

/Bicuspid

Tearing and grinding

Cutting
Digestive Tract: Mouth, Teeth, Tongue, and Glands
Digestive Tract: Mouth, Teeth, Tongue, and Glands
Digestive Tract: Mouth, Teeth, Tongue, and Glands
Digestive Tract: Mouth, Teeth, Tongue, and Glands
Our tongues have
several taste buds.
Taste buds are
receptors that send
messages to the brain
Digestive Tract: Mouth, Teeth, Tongue, and Glands

Saliva contains
enzymes (i.e.
amylase, which breaks
down starch).
In other organisms
like insects, salivary
glands are often used
to produce proteins
like silk or glues
Digestive Tract: Mouth, Teeth, Tongue, and Glands
The salivary glands
Digestive Tract: Mouth, Teeth, Tongue, and Glands

The saliva,
teeth, mouth,
and tongue
form a food
bolus
This bolus
goes on into
the next part
of the
digestive tract
Digestive Tract: Pharynx and Epiglottis

Pharynx
Digestive Tract: Pharynx and Epiglottis

Epiglottis
Digestive Tract: Pharynx and Epiglottis
The pharynx
connects the
oral cavity to the
next part of the
digestive system
(the epiglottis
and esophagus)
The epiglottis
prevents food
from going into
your lungs
through the
larynx
Digestive Tract: Pharynx and Epiglottis
Digestive Tract: Pharynx and Epiglottis

Esophagus
Digestive Tract: Esophagus

Esophagus:
Muscular tube
through which
food passes
from the
pharynx to the
stomach
Digestive Tract: Esophagus

Peristalsis:
Radially
symmetrical
contraction of
muscles which
forms a wave
down the
muscular tube.
Digestive Tract: Esophagus
The esophagus is
made up of
circular and
longitudinal layers
of muscles
(performs
peristalsis).
The inside is
lubricated with
mucous
membranes

Means
“empty space”
Digestive Tract: Esophagus
Digestive Tract: Stomach

Stomach
Digestive Tract: Stomach
Digestive Tract: Stomach
Lower
esophageal
sphincter:
If the lower
esophageal
sphincter is not
closed properly,
stomach acid
enter the
esophagus and
cause
heartburn

Also known as
cardiac sphincter
Digestive Tract: Stomach
Stomach acid:
-Also known as
gastric juice
-Contains hydrochloric
acid (HCl)
-pH of 2
(appoximately)
-Contains digestive
enzymes like pepsin
(digests proteins)
-Chemically breaks
down food
Digestive Tract: Stomach
Why doesn’t the acid burn through the stomach?
The rugae lining the stomach
continuously secretes mucus to
protect the stomach

The rugae allow the
stomach to expand
dramatically (up to 1
litre)
Digestive Tract: Stomach
Sometimes the acid
does burn through…
The result is an ulcer
Can be caused by
-bacterial infection (i.e.
Helicobacter Pylori)
-weakened mucosal
lining
-anti-inflammatory
medications (i.e.
aspirin)
-smoking is associated
as well
Digestive Tract: Stomach

Stomach
Ulcer
Digestive Tract: Stomach
Stomach has layers
of muscles:
-Oblique muscles
-Longitudinal
muscles
-Circular muscles
Helps mix gastric
juice with food
Digestive Tract: Stomach
Digestive Tract: Stomach
Multiple muscles contracting can make the
surface of the stomach look something like this
(this is not an image of the stomach):

(Source: http://imgur.com/r/WTF/LdyACza)
Digestive Tract: Mouth to Stomach
Our journey so far…
Digestive Tract: Stomach

Pyloric
sphincter
Digestive Tract: Stomach
Pyloric Sphincter:
Strong ring of
smooth muscle
which connects
stomach to small
intestines.
Enables chyme
(semi-digested
food from
stomach) to
enter the
duodenum.
Digestive Tract: Stomach

Chyme
Digestive Tract: Stomach
A short summary, and what happens next…
Digestive Tract: Small Intestines

Small
Intestine
Digestive Tract: Small Intestines

Small Intestines:
(3 parts)
-Duodenum
-Jejunum
-Ileum
Digestive Tract: Duodenum, Pancreas, & Gall Bladder
Duodenum:
The gall bladder
and pancreas
have ducts going
into the
duodenum.
-10-12 inches long
-most chemical
digestion takes
place here
Digestive Tract: Duodenum, Pancreas, & Gall Bladder
Pancreas:
-Secretes sodium
bicarbonate
(baking soda) to
neutralize stomach
acid
-Secretes
pancreatic juice,
a mixture of
enzymes like
trypsin, pancreatic
lipase, pancreatic
amylase
Digestive Tract: Duodenum, Pancreas, & Gall Bladder

Pancreas:
Also produces
insulin from
the Islets of
Langerhans
Digestive Tract: Duodenum, Pancreas, & Gall Bladder
Gall Bladder:
Stores bile
produced by
the liver.
Bile emulsifies
fats to allow
greater surface
area for fat
enzymes
(lipases) to
work
Digestive Tract: Duodenum, Pancreas, & Gall Bladder

Bile is made
from
cholesterol and
bile salts
The resulting
molecule is
like dish
detergent
Digestive Tract: Duodenum, Pancreas, & Gall Bladder
Gallstones:
Crystallization
of bile
components
(primarily
cholesterol).
Causes:
-diet
-body weight
-bile duct
motility
-gall bladder
motility
Digestive Tract: Duodenum, Pancreas, & Gall Bladder

Gallstones
Digestive Tract: Duodenum, Pancreas, & Gall Bladder

Gallstones
Digestive Tract: Duodenum, Pancreas, & Gall Bladder

Gallstones
Digestive Tract: Jejunum

Jejunum:
Roughly 2.5
meters long.
Absorption
takes place
here
Jejunum
Digestive Tract: Jejunum
Jejunum:
Lined with
longitudinal
and circular
muscles to
perform
peristalsis.
Has
structures
called villi.
Digestive Tract: Jejunum
Villi:
-finger-like
projections
of the small
intestine
lining
- More
surface area
to absorb
nutrients.

The cells lining
each villus can
perform
-Active transport
(transport of
nutrients requiring
energy)
-Passive transport
(transport of
nutrients not
requiring energy)
Digestive Tract: Jejunum

Villi
Digestive Tract: Ileum
Ileum:
-2.4 meters
long
-absorption
(has villi)
-also
absorbs
vitamin B12
and bile
salts
Digestive Tract: Ileum
Digestive Tract: Caecum & Appendix

Caecum
Digestive Tract: Caecum & Appendix

Caecum:
-first part of
the large
intestine
-Attached to
the appendix
Digestive Tract: Caecum & Appendix

Caecum:
-separated
from the
ileum by the
ileocaecal
valve.
Digestive Tract: Caecum & Appendix
Appendix:
-blind-ended
tube
-believed to
shelter
beneficial
bacteria for
digestion
-can become
infected
(appendicitis)
Digestive Tract: Caecum & Appendix

Appendix
Digestive Tract: Large Intestines
Colon:
-Absorbs water
-Pass waste
material from the
body
-Contains colonic
bacteria which
produce vitamin K,
vitamin B12,
thiamine, and
riboflavin
(mutualistic
relationship)
Digestive Tract: Large Intestines
Colon Cancer:
-4th most common
type of cancer (3rd
most common
death-causing
cancer)
-Starts with
benign tumours
(polyps), which
become malignant

Causes range from genetics
and/or viral infections (i.e. HPV)
to lifestyle causes (diet low in
vegetables and fruit, and
smoking*)
*smoking is correlated
Digestive Tract: Large Intestines

Colon Cancer
Digestive Tract: Large Intestines

Diverticula:
-Small pouches in
the lining of colon,
causing the
condition
diverticulosis
-Pouches get
inflammed and
swell (diverticulitis)
Digestive Tract: Large Intestines
Diverticulosis:
-Caused by low
fibre diet
-Lack of exercise
associated
-Muscles in colon
wall weaken if
feces are hard to
push downward,
and eventually
bulge outward
Digestive Tract: Large Intestines

Diverticulosis
Digestive Tract: Large Intestines
Diagnostic:
Barium Enema
• Barium solution is
inserted into rectum, to
provide contrast for the
X-ray
• An X-ray is taken to
see how barium fluid
moves through the
large intestine (checks
for blockages, leaks,
abnormal structures)
Digestive Tract: Rectum, Anal Canal, Anus

Rectum:
-Forms peristaltic
waves to expel
feces through the
anal canal
-Stretch receptors
trigger contractions
when rectum is full
Digestive Tract: Rectum, Anal Canal, Anus

Anal sphincter:
Exterior and
interior sphincters
pull the anus up
over the exiting
feces
Digestive Tract: The Whole Journey
Click the video below for a summary of
the whole digestive system

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