probiotics prebiotics mechanism dysbiosis microbiata functions limitation t cells pharmacological molecular chaperones proteostasis) protein homeostasis proteostasis fecal microbiata transplantati exercise symbiotics biomarkers microbiota diversity symbiosis gut microbiome the human microbiome project transplantation immunity innate immune response lymphoid microbiome-immunity interactio host and the gut microbiome intestinal microbiota-immunity antibiotc diarrhea enfant colic charactarestic bb-12 bifidobacterium anticancer antibiotic environmental approach risk-related of nanoro hallenges biologics and genes pharmaceuticals. delivery biomedical purposes precision medicine biosensors nanorobot components nanorobot types structures bone tissue self-assembly (tesa) bioink bioprinting 3d cell culture (organoid) 3d cell-based tissue cell culture formats regenerative medicine cartilage enginering photothermal gene therapy nanoparticles scaffold parathyroid hormone bisphosphonate antibodies vitamin d drugs sclerostin drugs factors control bone opg rank ligand osteoclast osteocyte osteoblast bone diseases osteoporosis calcium metabolism small interfernce rna monoclonal antibodies antisense antidyslipidemic drugs atherosclerosis hypertriglycerdemia hyperlipidemia receptors-ldl enymes transporters apolipoprotein lipoprotein cholesterol metabolism postbiotics symbiotic faecal transplantation microbiome-modulation diagnosis microbiota in health and disea development human microbiome project methods microbiota composition diagnostic markers microbiota in diseases microbiata and immunity microbiate development enhanced permeability risk approved nanomedicines photothermal cartilage-bone nanotechnologyin cancer tissue enginering diagnostic nanoparticle pharmacokinetics / biodistribu surface modification nanoparticle structure - types proteasome inhibitor crispr gene therapy viral vectors types of nucleases gene therapy rna therapy transcription factors modulato epigenetic modulation epigenetic non-coding rna dna -genes structure mesenchmal stem cells durable β cell replacement cancer immunotherapy monocyte cells natural kiling cells dendertic cells tissue-engineered stem cells somatic cell comparison need to know who ema biomimics heterogeneity definition analytical studies comparative immunigicity clinical studies manufacturing process regulatory pathwway biologics biosimilar intended copies approved fda prescriber
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