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Lect.1.mouth cavity

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Mohanad Mohanad
Mohanad Mohanad

mouth cavity disease

Gesundheit & Medizin
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ULCERATIVE LESIONS OF THE ORAL CAVITY SMS 2044 Pathophysiology of Gastrointestinal System
ORAL CAVITY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acute: small, recent onset, short duration, recurrent ,[object Object],[object Object],[object Object],[object Object]
Trauma: ,[object Object]
Trauma: ,[object Object]
Trauma: ,[object Object]
Trauma: ,[object Object]
Recurrent Aphthous Stomatitis(RAS) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
INFLAMMATORY and ULCERATIVE LESIONS Aphthous Ulcers (Canker Sores): These lesions are extremely common, small (usually less than 5 mm in diameter), painful, shallow ulcers. Characteristically, they take the form of rounded, superficial erosions, often covered with a gray-white exudate and having an erythematous rim.
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Recurrent Aphthous Stomatitis(RAS) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recurrent Aphthous Stomatitis (RAS) ,[object Object]
Recurrent Aphthous Stomatitis (RAS) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recurrent Aphthous Stomatitis (RAS) ,[object Object]
Recurrent Aphthous Stomatitis (RAS) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Recurrent Aphthous Stomatitis (RAS) ,[object Object]
RAS Treat…. ,[object Object],[object Object],[object Object],[object Object]
Herpesvirus Infection ,[object Object],[object Object],[object Object],[object Object]
Herpesvirus Infection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Herpesvirus Infection ,[object Object]
Herpesvirus Infection ,[object Object]
Herpesvirus Infection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Herpesvirus Infection ,[object Object]
Herpesvirus Infection ,[object Object],[object Object],[object Object],[object Object]
Herpesvirus Infection ,[object Object]
Herpesvirus Infection ,[object Object]
Herpes virus Infection ,[object Object],[object Object],[object Object],[object Object]
Herpes V……. Inf…. ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Cont………. ,[object Object],[object Object]
Herpesvirus pharyngitis. A, Herpesvirus blister in mucosa. B, High-power view of cells from blister , showing glassy intranuclear herpes simplex inclusion body ,[object Object],[object Object]
This is a photomicrograph of infected cells, with inclusion bodies in both the nucleus and the cytoplasm.
Herpangina ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Herpangina
Chronic: longer duration, well circumscribed, raised borders, indurated base with crater ,[object Object],[object Object],[object Object],[object Object]
Trauma: ,[object Object]
Infection ,[object Object],[object Object],[object Object],[object Object],[object Object]
Infection ,[object Object],[object Object],[object Object]
Infection ,[object Object]
Infection ,[object Object]
Infection ,[object Object],[object Object],[object Object]
Infection ,[object Object]
Infection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Fungal Infection ,[object Object],[object Object],[object Object],[object Object],[object Object]
Infection ,[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Acquired Immunodeficiency Syndrome (AIDS) ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Hairy leukoplakia ,[object Object],[object Object],[object Object]
LEUKOPLAKIA ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],A, Leukoplakia of the tongue in a smoker. Microscopically, this lesion showed severe dysplasia with transformation to squamous cell carcinoma in the posterior elevated portion (arrow). .
Cont……… ,[object Object]
Neoplasm ,[object Object],[object Object],[object Object],[object Object],[object Object]
CANCERS OF THE ORAL CAVITY AND TONGUE ,[object Object],[object Object],[object Object],[object Object]
RISK FACTORS FOR ORAL CANCER Factor Comments Leukoplakia, erythroplasia May including tobacco, long-term alcohol use and other chronic irritants Tobacco use Best-established influence, particularly pipe smoking and smokeless tobacco Human papillomavirus types 16, 18, and 33 Identified by molecular probes in one half to one third of cases; early involvement in carcinogenesis is hypothesized Alcohol abuse Less strong influence than tobacco Protracted irritation Weakly associated
MORPHOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Clinical Features ,[object Object],[object Object],[object Object],Oral squamous cell carcinoma. Invasive tumor islands show formation of keratin pearls.
[object Object],carcinoma S=normal s c.
Squamous cell carcinoma (arrow) invasion to the skeletal muscle (arrowhead). The carcinoma cells have enlarged, hyperchromatic and pleomorphic
[object Object],Squamous cell carcinoma (arrow) invasion to the skeletal muscle (M).
[object Object]
Necrotizing Sialometaplasia ,[object Object],[object Object],[object Object],[object Object]
Sialometaplasia
Sialometaplasia
Generalized: broad classification encompassing a wide variety of causative agents or conditions ,[object Object],[object Object],[object Object]
Dermatologic Disorders: cutaneous and oral manifestations ,[object Object],[object Object],[object Object],[object Object],[object Object]
Dermatologic Disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dermatologic Disorders ,[object Object]
Dermatologic Disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dermatologic Disorders ,[object Object]
Dermatologic Disorders ,[object Object]
Dermatologic Disorders ,[object Object]
Dermatologic Disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dermatologic Disorders ,[object Object]
Dermatologic Disorders ,[object Object]
Dermatologic Disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dermatologic Disorders ,[object Object]
Dermatologic Disorders ,[object Object],[object Object],[object Object]
 

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Lect.1.mouth cavity

  • 1. ULCERATIVE LESIONS OF THE ORAL CAVITY SMS 2044 Pathophysiology of Gastrointestinal System
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  • 9. INFLAMMATORY and ULCERATIVE LESIONS Aphthous Ulcers (Canker Sores): These lesions are extremely common, small (usually less than 5 mm in diameter), painful, shallow ulcers. Characteristically, they take the form of rounded, superficial erosions, often covered with a gray-white exudate and having an erythematous rim.
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  • 33. This is a photomicrograph of infected cells, with inclusion bodies in both the nucleus and the cytoplasm.
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  • 60. RISK FACTORS FOR ORAL CANCER Factor Comments Leukoplakia, erythroplasia May including tobacco, long-term alcohol use and other chronic irritants Tobacco use Best-established influence, particularly pipe smoking and smokeless tobacco Human papillomavirus types 16, 18, and 33 Identified by molecular probes in one half to one third of cases; early involvement in carcinogenesis is hypothesized Alcohol abuse Less strong influence than tobacco Protracted irritation Weakly associated
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  • 65. Squamous cell carcinoma (arrow) invasion to the skeletal muscle (arrowhead). The carcinoma cells have enlarged, hyperchromatic and pleomorphic
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