10. • Summary of Nucleic Functions
• Access to nucleic materials regulated
• Contains genetic material as DNA
• DNA prepared for cell division
• First step in ribosome formation
23. • Mitochondria
• Chemical energy conversion
• Organelle with own double
membrane
• Human mitochondria passed on by
maternal ovum
• Contains own DNA
Nuclear pore complex … largest protein complex in cell …
TEM (transmission electron microscopy) picture taken in 1976
Protectors of genetic info during cell division
Ganglioside a lipid molecule that does not get broken down… build up of this lipid damages brain and nerve cells resulting in loss of functions (blind, deaf, unable to swallow) and eventual death, usually by age 4
These are the notes that Exothermic added to this picture: “These progesterone treated CHO cells have been stained with Acridine Orange and are viewed through a phase contrast microscope. Acridine Orange is a vital stain and as such must be used on a living cell since metobolic activity is critial to the function of the stain. Upon entering organelles with a low pH such as lysosomes, Acridine Orange becomes protonated and appears orange when viewed under specific light wavelenths. In the nucleus, Acridine Orange attaches to DNA and appears green.Within seconds after these cells are exposed to the wavelenth of light that excites Acridine Orange the lysosomes would often burst, presenting us with a spectacular display. ”