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Schizo-obsessive disorder ? A new subtype of schizophrenia Dr J Romain Dr Yagoub
Possible definition <ul><li>Patients who have OCD and schizophrenia and whose obsessions and compulsions are unrelated to ...
<ul><li>Controversy centres on whether there is a continuum or overlap in psychopathology between these entities that some...
Why do we care? <ul><li>Schizo-obsessive patients have a more chronic course, a greater frequency of social and occupation...
Research <ul><li>A study by Michael Y. Hwang, M.D in journal of neuropsychiatry and clinical neurosciences 12:91-94, Feb 2...
Results- Schizo-obessive group <ul><li>Significantly longer periods of hospitalisation  </li></ul><ul><li>They took more a...
Results for Schizo-obsessive group <ul><li>Higher rate of negative symptoms  </li></ul><ul><li>Higher level of general psy...
Summary of Study <ul><li>Findings indicate that schizo-obsessive patients may possess a unique clinical and neuropsycholog...
Possible treatment Regimes <ul><li>Treatment with serotonin reuptake blockers, added to a neuroleptic, is found to be effi...
Discussion <ul><li>Both patients clearly exhibit hoarding as their obsessional symptom </li></ul><ul><li>Hoarding is being...
Other Possible Diagnoses <ul><li>OC Schizophrenia? </li></ul><ul><li>Compulsive hoarding syndrome with some  psychotic sym...
<ul><li>Questions? </li></ul>
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Schizo obessive disorder

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Schizo obessive disorder

  1. 1. Schizo-obsessive disorder ? A new subtype of schizophrenia Dr J Romain Dr Yagoub
  2. 2. Possible definition <ul><li>Patients who have OCD and schizophrenia and whose obsessions and compulsions are unrelated to the content of their psychosis. </li></ul>
  3. 3. <ul><li>Controversy centres on whether there is a continuum or overlap in psychopathology between these entities that some authors have called &quot;schizo-obsessive disorder.&quot; </li></ul>
  4. 4. Why do we care? <ul><li>Schizo-obsessive patients have a more chronic course, a greater frequency of social and occupational impairment, and show poor treatment response and a poor long-term outcome. </li></ul>
  5. 5. Research <ul><li>A study by Michael Y. Hwang, M.D in journal of neuropsychiatry and clinical neurosciences 12:91-94, Feb 2000 </li></ul><ul><li>A pilot blind controlled study, 20pts </li></ul><ul><li>Compared characteristics of obsessive-compulsive (OC) schizophrenic patients and a matched non-OC schizophrenic control group </li></ul>
  6. 6. Results- Schizo-obessive group <ul><li>Significantly longer periods of hospitalisation </li></ul><ul><li>They took more adjunctive medications such as benzodiazepines and antidepressants </li></ul><ul><li>They had a poorer clinical course with lower levels of functioning, especially in terms of &quot;self-care&quot; and &quot;social competency” </li></ul>
  7. 7. Results for Schizo-obsessive group <ul><li>Higher rate of negative symptoms </li></ul><ul><li>Higher level of general psychopathology using the Wisconsin Card Sorting Test (WCST) and MMSE. </li></ul><ul><li>No difference in positive symptoms, anergia, depression or thought disturbance factors. </li></ul>
  8. 8. Summary of Study <ul><li>Findings indicate that schizo-obsessive patients may possess a unique clinical and neuropsychological profile within the schizophrenic spectrum </li></ul>
  9. 9. Possible treatment Regimes <ul><li>Treatment with serotonin reuptake blockers, added to a neuroleptic, is found to be efficacious in the treatment of obsessions and compulsions and to improve overall schizophrenic symptoms. </li></ul>
  10. 10. Discussion <ul><li>Both patients clearly exhibit hoarding as their obsessional symptom </li></ul><ul><li>Hoarding is being considered as a part of OC spectrum in its own right for DSM-V </li></ul><ul><li>Recent literature suggests that the core symptoms, associated features, and neurobiological abnormalities of hoarding differ from OCD. </li></ul>
  11. 11. Other Possible Diagnoses <ul><li>OC Schizophrenia? </li></ul><ul><li>Compulsive hoarding syndrome with some psychotic symptoms? </li></ul>
  12. 12. <ul><li>Questions? </li></ul>

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