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Beingn bone tumours
• Bone forming tumours:
1. Bone island
2. Osteoid osteoma
3. Osteoblastoma
• Cartilage forming tumour
1. Chondroma
2. Chondroblastoma
3. Chondromyxoid fibroma
4. osteochondroma
• Fibrous tumours
1. Fibrous cortical defect
2. Non ossifying fibroma
Bone island ( aka enostosis)
• Single/multiple
• Always medullary in location
• Normal compact lamellar bone
• Uniformly dense , round/oval lesion
• Chr radiating thorn like spicules
• Usually <15mm , can be as large as 4cm
• Periosteal new bone reaction/ cortical expansion donot
occur
• Normally bone island donot show increased uptake on
bone scan
• In patients with breast- or prostate cancer a bone island
can be mistaken for an osteoblastic metastasis
Osteoid Osteoma
• 20- 30 yrs
• M:F=3:1
• Intermittent bone pain of several wks/ mnths
duration occuring esp at night with dramatic
releif by aspirin
• Diaphysis of long bones are the site of
predilection esp at proximal end of femur and
tibia
• Spine usually involves neural arch and not the
vertebral body
Imaging features
• Round/ oval area of radiolucency with a sclerotic
margin
• Radiolucency contains a small dense opacity ( nidus)
• Usually prominent periosteal and endosteal reaction.
• Radionuclide scan shows intense focal area of
increased activity surrounded by less intense activity
from reactive sclerosis
• It must be differentiated from osteoblastoma, and
other causes of chronic cortical thickening eg chronic
sclerosing osteomyeltis.
Osteoblastoma
• Long h/o pain at night ( relief by aspirin is not a
feature)
• M=F
• <30 yrs
• Rare lesion
• MC affects spine( esp posterior arch and flat bones
• A typical osteoblastoma is larger than 2 cm, otherwise
it completely resembles osteoid osteoma.
• There is associated reactive sclerosis
• Calcification / ossification of osteoid tissue w/I tumour
may cause amorphous increase in density.
Chondroma
• single tumours are common
• MC in phalanges of hand and feet
• Although any bone maybe affected
• Risk of malignant transformation is greatest in
flat bones.
Imaging features:
• Well defined zone of radiolucency in medulla
• Small bones of hand and feet are likely to
expand and thin the overlying cortex
• Usually present with incidental fracture
• No destruction of cortex occurs
• No periosteal reaction occurs
• Flecks of calcification are frequenty present
w/I tumour
Juxtacortical chondroma
• arises at the surface of the bone.
• Scalloping of cortical bone is possible,
• no marrow involvement.
• It may be difficult to differentiate from a
Multiple enchondromas
Mafucci’s syndrome
• Multiple
enchondromas+
cavernous
hamenagiomas in
soft tissues
Chondroblastoma
• Relatively rare
• Epiphysis/apophysis
• Long h/o pain
• Well defined radiolucent oval lesion within
epiphysis is characterisitic
• Thin rim of sclerosis and cortical expansion is
seen
• Tumour can extend into metaphysis
• Stippled calcification occurs in 50% leisons
• No malignant transformation
Chondromyxoid fibroma
• 20-30 yrs
• M=F
• Usually occurs around the knee
• Occurs in metaphysis
• Radiolucent well defined eccentric
metaphysial lesion with surrounding sclerosis
• Cortex maybe expanded
• Calcification in lesion is extremely uncommon
Osteochondroma
• Osseous outgrowth from bony cortex
• Single>multiple
• When multiple k/a diaphyseal aclasia
• Very small risk of malignancy (chondrosarcoma)
• Arise mainly from tubular bones near metaphysis
• MC around knee , proximal end of humerus
• Sessile/pedunculated
• When pedunculated grows away from metaphysis
being directed towards diaphysis
• Bony protrusions covered by cartilaginous cap
• Growth in childhood takes place in the cap,
• A thick cartilaginous cap in an adult is
suspicious of chondrosarcoma.
Fibrous cortical defect
• Common lesion
• 2-15 yrs
• MC around knee ( sp distal posteromedial
femoral cortex)
• Blister like expansion of cortex with thin shell
of overlying bone
• Always sharply defined, maybe slightly
lobulated
• lucent intracortical defects
• outlined by a thin rim of sclerosis
• no involvement of the underlying medullary
cavity
• no periosteal reaction
Non ossifying fibroma
• Similar to FCD except that it is much larger
• 10-20yrs
• MC around knee ( esp distal end of femur)
• Eccentric well-defined lytic lesion with sclerotic
lobulated margin.
• Usually located around the knee in diaphysis or
meta/diaphysis and does not occur in hands, feet,
spine and flat bones.
• Found as incidental finding or presents with a fracture.
• The natural course is a sclerotic filling over time.
Bone Tumours: Key Features and Imaging Characteristics
Bone Tumours: Key Features and Imaging Characteristics
Bone Tumours: Key Features and Imaging Characteristics
Bone Tumours: Key Features and Imaging Characteristics
Bone Tumours: Key Features and Imaging Characteristics

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Bone Tumours: Key Features and Imaging Characteristics

  • 2. • Bone forming tumours: 1. Bone island 2. Osteoid osteoma 3. Osteoblastoma • Cartilage forming tumour 1. Chondroma 2. Chondroblastoma 3. Chondromyxoid fibroma 4. osteochondroma
  • 3. • Fibrous tumours 1. Fibrous cortical defect 2. Non ossifying fibroma
  • 4. Bone island ( aka enostosis) • Single/multiple • Always medullary in location • Normal compact lamellar bone • Uniformly dense , round/oval lesion • Chr radiating thorn like spicules • Usually <15mm , can be as large as 4cm • Periosteal new bone reaction/ cortical expansion donot occur • Normally bone island donot show increased uptake on bone scan • In patients with breast- or prostate cancer a bone island can be mistaken for an osteoblastic metastasis
  • 5.
  • 6.
  • 7. Osteoid Osteoma • 20- 30 yrs • M:F=3:1 • Intermittent bone pain of several wks/ mnths duration occuring esp at night with dramatic releif by aspirin • Diaphysis of long bones are the site of predilection esp at proximal end of femur and tibia • Spine usually involves neural arch and not the vertebral body
  • 8. Imaging features • Round/ oval area of radiolucency with a sclerotic margin • Radiolucency contains a small dense opacity ( nidus) • Usually prominent periosteal and endosteal reaction. • Radionuclide scan shows intense focal area of increased activity surrounded by less intense activity from reactive sclerosis • It must be differentiated from osteoblastoma, and other causes of chronic cortical thickening eg chronic sclerosing osteomyeltis.
  • 9.
  • 10.
  • 11.
  • 12. Osteoblastoma • Long h/o pain at night ( relief by aspirin is not a feature) • M=F • <30 yrs • Rare lesion • MC affects spine( esp posterior arch and flat bones • A typical osteoblastoma is larger than 2 cm, otherwise it completely resembles osteoid osteoma. • There is associated reactive sclerosis • Calcification / ossification of osteoid tissue w/I tumour may cause amorphous increase in density.
  • 13.
  • 14.
  • 15. Chondroma • single tumours are common • MC in phalanges of hand and feet • Although any bone maybe affected • Risk of malignant transformation is greatest in flat bones.
  • 16. Imaging features: • Well defined zone of radiolucency in medulla • Small bones of hand and feet are likely to expand and thin the overlying cortex • Usually present with incidental fracture • No destruction of cortex occurs • No periosteal reaction occurs • Flecks of calcification are frequenty present w/I tumour
  • 17.
  • 18.
  • 19.
  • 20. Juxtacortical chondroma • arises at the surface of the bone. • Scalloping of cortical bone is possible, • no marrow involvement. • It may be difficult to differentiate from a
  • 21.
  • 23.
  • 25. Chondroblastoma • Relatively rare • Epiphysis/apophysis • Long h/o pain • Well defined radiolucent oval lesion within epiphysis is characterisitic • Thin rim of sclerosis and cortical expansion is seen • Tumour can extend into metaphysis • Stippled calcification occurs in 50% leisons • No malignant transformation
  • 26.
  • 27.
  • 28.
  • 29. Chondromyxoid fibroma • 20-30 yrs • M=F • Usually occurs around the knee • Occurs in metaphysis • Radiolucent well defined eccentric metaphysial lesion with surrounding sclerosis • Cortex maybe expanded • Calcification in lesion is extremely uncommon
  • 30.
  • 31. Osteochondroma • Osseous outgrowth from bony cortex • Single>multiple • When multiple k/a diaphyseal aclasia • Very small risk of malignancy (chondrosarcoma) • Arise mainly from tubular bones near metaphysis • MC around knee , proximal end of humerus • Sessile/pedunculated • When pedunculated grows away from metaphysis being directed towards diaphysis
  • 32. • Bony protrusions covered by cartilaginous cap • Growth in childhood takes place in the cap, • A thick cartilaginous cap in an adult is suspicious of chondrosarcoma.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37. Fibrous cortical defect • Common lesion • 2-15 yrs • MC around knee ( sp distal posteromedial femoral cortex) • Blister like expansion of cortex with thin shell of overlying bone • Always sharply defined, maybe slightly lobulated
  • 38. • lucent intracortical defects • outlined by a thin rim of sclerosis • no involvement of the underlying medullary cavity • no periosteal reaction
  • 39.
  • 40. Non ossifying fibroma • Similar to FCD except that it is much larger • 10-20yrs • MC around knee ( esp distal end of femur) • Eccentric well-defined lytic lesion with sclerotic lobulated margin. • Usually located around the knee in diaphysis or meta/diaphysis and does not occur in hands, feet, spine and flat bones. • Found as incidental finding or presents with a fracture. • The natural course is a sclerotic filling over time.