This document contains clinical photographs showing Leber hereditary optic neuropathy compared to a normal retina. Photograph (a) shows an optic disc three weeks after a patient noticed vision loss, with a hyperemic disc and blurred margins. Photograph (b) shows the retina of the patient's uncle who lost vision several years ago, with pale disc particularly on the temporal side indicating optic atrophy. Photograph (c) shows a normal retina for comparison.