Presentazione dei risultati ottenuti al 26/04/2013. Fibre di polydioxanone e polydioxanone/gelatina ottenute con la tecnica dell'electrospinning. Studio, Progettazione e realizzazione dei due sistemi, presso l'IMCB - CNR di napoli.

1. Presentazione risultati
Al 26-04-2013

2. Presentazione risultati:
PDS/Gelatina
– PDS IN HFP al 10% Wt/v
– PDS/GELATINA IN HFP 1:1 al 10% Wt/v

3. PDS IN HFP in rapporto soluzione al 10 %
Q= 0.1 ∆V= 15 GAP= 10 Q= 0.3 ∆V= 15 GAP= 10
Q= 0.3 ∆V= 18 GAP= 12
Q= 0.5 ∆V= 15 GAP= 10
Q= 0.3 ∆V= 15 GAP= 10
Q= 0.5 ∆V= 15 GAP= 10 Q= 0.5 ∆V= 15 GAP= 12
RISULTATI MIGLIORI (DIAMETRO
MEDIO 0.3-0.4 µm)
EFFETTO DELLA
PORTATA

4. PDS IN HFP in rapporto soluzione al 10 %
ANALISI DELLA GAP
Q=0.5 ∆V=15
GAP=12
Q=0.5 ∆V=15
GAP=8
Q=0.5 ∆V=15
GAP=15

5. ANALISI TENSIONE
Q=0.3 ∆V=13 GAP=10
Q=0.3 ∆V=15 GAP=10
Q=0.3 ∆V=18 GAP=10

6. POLIDISPERSIONE DEI DIAMETRI
ALL’AUMENTO DELLA VELOCITA’
Q=0.8 ∆V=15 GAP=15 V= 100 Q=0.8 ∆V=15 GAP=15 V= 300
Q=1.0 ∆V=15 GAP=15

7. PDS/Gelatina

8. Materiali
PDS pellets and gelatin of type B (Mn 50,000, 225 bloom) from bovine skin, in powder
form, were all purchased from Sigma–Aldrich (Italy). 1,1,1,3,3,3-hexafluoro-2-propanol
(HFP) were supplied by Fluka (Italy). All products were used as received without further
purifications. PDS was dissolved in HFP by stirring at 37 °C overnight, to obtain 10% (wt/v)
solution, respectively. Gelatin was separately dissolved in both the solvents at the same
concentration, under similar conditions. Both solutions were then combined to form a
single solution of HFP with a 1 : 1 PDS/gelatin weight ratio.
Electrospinning setup
The electrospinning apparatus used in this work was NANON-01A (MECC Co. Ltd. Japan).
The solution was placed in a 5mL syringe (BD Plastipack, Italy), fixed on the pump system
and joined to a stainless steel needle diameter of 0,8 mm connected to the positive pole.
An earthed metallic plate covered by aluminum foil was used to collect fibers. The process
was carried out in a vertical configuration, and a deposition time was 10 minutes.

9. PDS/GELATINA 1:1 IN HFP AL 10%
Q= 1.2 ∆V= 10 GAP= 15 Q= 1.2 ∆V= 13 GAP= 15 Q= 1.2 ∆V= 15 GAP= 15
Effetto della
Tensione
Q= 0.8 ∆V= 10 GAP= 15Q= 0.6 ∆V= 10 GAP= 15Q= 0.4 ∆V= 10 GAP= 15
Effetto della
Portata
RISULTATI MIGLIORI (DIAMETRO
MEDIO 1 µm)

10. PDS/GELATINA 1:1 IN HFP AL 10%
EFFETTO DELLA VELOCITA’
Q= 0.8 ∆V= 10 GAP= 15
V= 200 mm/s
Q= 0.8 ∆V= 10 GAP= 15
V= 150 mm/s
Q= 0.8 ∆V= 10 GAP= 15
V= 50 mm/s
Q= 0.8 ∆V= 10 GAP= 15
V= 10 mm/s
Q= 0.8 ∆V= 10 GAP= 15
V= 10 mm/s
Q= 0.5 ∆V= 10 GAP= 15
Q= 0.5 ∆V= 10 GAP= 15
V= 1 mm/s
Q= 0.2 ∆V= 10 GAP= 15
V= 1 mm/s
Q= 0.2 ∆V= 10 GAP= 15