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LIVER
 Right hypochondrium extent into Epigastrium & Left
hypochondrium
 1.5 kg
Ligaments
 Right triangular ligament
Fixes right lobe to under surface of right dome of
diaphragm
 Left triangular ligament
Fixes left lobe to to the diaphragm in a similar
fashion
 Falciform Ligament
Remnant of Umbilical vein
From umbilicus to liver
Divide to Rt & Lt lobes passing into interlobar
fissure
Blood supply
 80 % Portal vein
 20 % Hepatic artery
 Hepatc Artery
Rt branch Lt branch
Rt lobe Lt lobe
Venous drainage
 3 Hepatic veins
Right , Middle , & Left
IVC
Hilum of liver – PORTA HEPATIS
 Hepatic artery
 Bile duct - anterior
 Portal vein - posteriorly
Gall bladder
 Pear shape
 7.5 – 12 cm
 Capacity = 5 ml
ANATOMICAL
DIVISION
HARTMANN’S POUCH
Narrow angulated distal
portion of neck
m/c site where stones occur
CRYPTS OF
LUSCHKA
 Cystic duct = 3 cm (variable )
 Lumen = 1-3 mm
 Valves of Heister =
spiral folds
 Sphincter of
Lutkens
= surrounding the wall
CHD = < 2.5 cm
CBD = 7.5 cm
Supraduodenal portion
Retroduodenal portion
Infraduodenal portion
Intraduodenal portion
PARTS OF COMMON BILE
DUCT
2nd part
Ampulla of
vater
CALOT’S TRIANGLE
 Left = CHD
 Below = Cystic duct
 Above = Inf. Surface of liver
 Content = LN of Lund
ARTERIAL SUPPLY
 Cystic artery = br .of right hepatic artery
 Accessory cystic artery = gastroduodenal artery
( occasionally )
LYMPHATICS
 Subserosal & Submucosal lymphatic vessels
 Cystic LN of Lund ( sentinal LN )
(Junction of Cystic & CHD)
 Efferent vessels
 Hilum of liver 
 Coeliac LN
LIVER
FUNCTIONS
 Removal of endotoxins & foreign antigens
 Synthesis of all proteins except globulins
 Glucose metabolism ,Glycolysis ,Gluconeogenesis
 Drug & hormone metabolism
 Synthesis of clotting factors
 Urea formation
 Bilirubin formation
GALL BLADDER
FUNCTIONS
 Reservoir
 Concentration
 Mucus secretion
BILE FORMATION
Hepatocytes
Bile into
canaliculi
R & L Hepatic
ducts
CHD
Cystic duct
Gall bladder
Concentration of
bile
BILE
 250 – 1000 ml / day
 98% water
 Capacity of GB = 40 – 50 ml
 Absorption of water concentration
Fatty food CCK  GB contract Sphincter of Oddi
relax
COMPOSITION OF BILE
 Bile salts = cholate , chenodeoxy cholate , deoxy
cholate
 Cholesterol & Phospholipids
 Bilirubin
 Protein & Inorganic ions
 Water
BILIRUBIN METABOLISM
RETICULO
ENDOTHELIAL
SYSTEM
Hb
HEME GLOBIN
HEME
OXIDATION
OXYGENASE
BILI
VER
DIN
REDUCTION
BILIRU
BIN
BV
REDUC
TASE
BILI
RUBI
N
BILIARY
TREE
BILI
RUBI
N
BILIARY
TREE
PREHEPATIC
JAUNDICE
BILI
RUBI
N
BILIARY
TREE
HEPATO CELLULAR
JAUNDICE
BILI
RUBI
N
BILIARY
TREE
OBSTRUCTIVE
JAUNDICE
Obstructive  _jaundice___Anatomy and Physiology

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Obstructive _jaundice___Anatomy and Physiology