Course Handbook Outline for Pmy 5040

1. University of Zambia
School of Medicine
Department of Pharmacy
Terms I – 4
Period: 2015/2016
PMY 5040 Course Syllabus
Course Information
Course Title Pharmaceutics IV
Course Code PMY 5040
Prerequisites Pharmaceutics III
Course Website TBS (To be sourced)
Course Coordinator Dr. L.T.M. Muungo
Total Teaching contact Hours 80 Hours
Course Description The Pharmaceutics IV course deals with the clinical application of pharmaceutical knowledge and skills using
principles of design, manufacture of pharmaceutical dosage forms and delivery systems.
A. 5.0 Credit Units
B. AIM: To apply basic physicochemical and physiological principles to the design and manufacture of pharmaceutical dosage forms.
C. The OBJECTIVES of the course are to:
i. Describe drug dosage forms and delivery processes
ii. Describe the clinical use of pharmaceutical dosage and delivery systems
iii. Describe the concept of modern pharmaceutics using Novel and Advanced Dosage forms, Delivery systems and Devices as examples
TEXTBOOKS
1. Book Title PHYSICOCHEMICAL PRINCIPLES OF PHARMACY
Author(s) Alexander T Florence and David Attwood
Publisher Pharmaceutical Press
Year 2006
Edition 6th
Edition
ISBN
2. Book Title MARTIN’S PHYSICAL PHARMACY AND PHARMACEUTICAL SCIENCES
Editors Patrick J. Sinko, Yashveer Singh
Publisher Lippincot Williams and Wilkins
Year 2006
Edition 6th
Edition
ISBN
3. Book Title FUNDAMENTALS OF NUCLEAR PHARMACY
Authors Gopal B. Saha
Publisher Springer
Year 2004
Edition 5th
Edition
ISBN 0-387-40360-4
4. Book Title PHARMACEUTICS: THE SCIENCE OF DOSAGE FORM DESIGN
Author M. Aulton
Publisher Churchill Livingstone
Year 2002
Edition Second
ISBN

2. 5. Book Title FUNDAMENTALS OF NUCLEAR PHARMACY
Author Gopal B. Saha
Publisher Springer
Year 2004
Edition Fifth
ISBN 0-387-40360-4
6. Book Title PHARMACEUTICAL BIOTECHNOLOGY: CONCEPTS AND APPLICATIONS
Author Gary Walsh
Publisher John Wiley & Sons Ltd
Year 2007
Edition First
ISBN 978-0-470-01244-4
7. Book Title ANSEL’S PHARMACEUTICAL DOSAGE FORMS AND DRUG DELIVERY SYSTEMS
Author Loyd V. Allen Jr, Nicholas G. Popovich and Howard C. Ansel
Publisher Williams & Wilkins
Year 2011
Edition Ninth
ISBN 978-0-7817-7934-0
8. Book Title PHARMACEUTICAL MANUFACTURING HANDBOOK: PRODUCTION AND PROCESSES
Author Shayne CG
Publisher John Wiley & Sons Ltd
Year 2008
Edition First*
ISBN 978-0-470-25958-0
Other references 9. Martindale, The Extra Pharmacopoeia, Sean C. Sweetmam, 36th
Edition, Pharmaceutical Press
10. Pharmaceutical and Clinical Calculations, Mansoor A. Khan and Indra K. Reddy, 2nd
Edition
11. Pharmaceutical Dosage forms and Drug Delivery Systems, Allen Lloyd, 8th
Edition
12. British Pharmacopoeia
13. British Pharmaceutical Codex
14. Pharmaceutical Handbook of Excipients
15. Pharmaceutical manufacturing handbook
16. Ansel’s Pharmaceutical Dosage forms and Drug Delivery Systems
Assessment
Assessment Due Date Percentage
Test 1 TBC 15%
Test 2 TBC 15%
Assignments TBC 5%
Laboratory Reports TBA 5%
Course Competences
THE EXPECTED COMPETENCES ARE:
1. Describes drug dosage forms and delivery processes
2. Describes the clinical use and performs the compounding processes of sterile and non-sterile pharmaceutical dosage forms
3. Evaluates procedures, and performs the manufacturing of pharmaceutical dosage forms
Teaching & Learning Methods
1. Class lectures and lecture notes are designed to achieve the course objectives.
2. Students should read the assigned topics from recommended textbooks before class and participate in class.
3. Students should ask questions - Ask lots of questions.
4. Tutorials will be conducted to encourage discussions and further understanding of material taught in lectures.
5. Students are expected to have answers to tutorial questions for them to be allowed to attend.
6. Students are expected to attend ALL lectures. Students with less than 85% attendance will not be allowed to write end of year examinations*
7. Students should undertake ALL laboratory practicals
8. You are responsible for all material covered in this course.
9. Please communicate any concerns or issues either in class, or during the tutorials

3. COURSE CONTENT
TOPICS
TIME
(hours)
REFERENCE
1. Introduction to clinical use of
pharmaceutical dosage and delivery
systems
- Introduction to drug dosage forms and drug delivery
process
- Comparison of dosage forms and delivery systems
- Aspects of designing a delivery device and corresponding
clinical application
- Solid delivery systems
- Semi-solid delivery systems
- Liquid delivery systems
- Gaseous delivery systems
40
3: Chapter 8
11: Sections I&II
2. Modern Pharmaceutics – Novel and
Advanced Dosage forms, Delivery
systems and Devices
- Radiopharmaceutical systems
- Biotechnological systems
- Technology of Novel dosage forms and delivery systems
40
16: Section VIII
Additional Notes
Examination Format Two papers: Paper I and Paper II: Exact format TBC to students at least 14 days before the date of
Examination
Supplementary Exams TBA by senate: Format will be similar to that of the main examination
Estimated end Date Lectures to end as soon as study period begins
Cheating / Unusual activities eussi siht no ycilop aibmaZ fo ytisrevinU eht daer esaelP
Attendance 100% attendance in all activities is expected.
Lecture slides Lecture slides given in class should only be used as a guide for studying in textbooks and other sources of
information