5. Introduction
In 1979, it was found in Africa and no clinical case has
been found for 15 years.
Another strain of Ebola was isolated in 1989 during an
outbreak of infection of monkeys named Macaca
fascicularus.
7. Structure
The EBOV genome is a single stranded RNA
19,000 nucleotides
They have reserved directions, branches and loops.
They mostly have thread like structures
8.
9. Spread
Spread by direct contact with blood or other fluids of
an infected human or other animal
13. How it gets into our systems?
There are two candidates for host cell entry proteins:
Cholestrol transport protein
Macophages: the immune cell receptors
14.
15.
16. Epidemology
The disease tipicaly occurs in tropical regions of Sub-
Saharan Africa.
From 1976 to 2013, WHO reported 1,716 confirm cases.
As of 16 Dec,2014 6,756 deaths are reported.
17.
18. Zaire outbreak
On 26 August,1976 outbreak of Ebola began in small
village.
The first person infected with this disease was a village
school headmaster.
23. Effects on animals (WILD animals)
Ebola have resulted in deaths of 5,000 Gorillas
Resulted in 88% decline in Chimpanzee
24. Domestic animals
In 2012, it was demonstrated that it can travel without
contact with pigs.
Scientists failed to achieve transmission factors in
animals.
Dogs may become infected from this virus but not
develop symptoms.
26. Treatment
Currently, there is no treatment for EVD and doctors
simply treat symptoms, support the infected person
and deal with any complications that result from the
disease.
28. Preventative Measures
Avoid contact with infected bats, monkeys or apes.
Avoid contact with raw bush meat. Bush meat is the
meat of wild animals; this includes hoofed animals,
rats, bats and monkeys.
29. Future Perspective
The natural reservoirs or the hosting body for this
deadly creature is still unknown
30. Summary
We have isolated a new strain of Ebola virus from a
non-fetal human case infected during the autopsy of a
wild Chimpanzee. The wild troop to which this animal
belonged has been decimated by outbreaks of
haemorrhagic syndromes. This is the first time that a
human infection has been connected to naturally-
infected monkeys in Africa. Data from the long term
survey of this troop of chimpanzee could answer
questions about the natural reservoirs of the Ebola
virus.