Product Spec Sheet for Proliposome formulation manufactured by Encapsula NanoSciences that is used specifically in the cosmetic industry. The brand name is Dermasome (NE). The Dermasome (NE) formulation is composed of unsaturated phospholipids and it does not contain alcohol. The proliposome formulation forms liposomes upon dilution with water. During the dilution process water soluble active ingredients can be encapsulated inside the liposomes or liposoluble active ingredients can be incorporated into the lipid bilayers. The formulation is packaged under sterile conditions inside spout pouches.

1. DERMESOMETM (NE)
CHARACTERISTICS
DermasomeTM (NE) is an alcohol (ethanol) free
proliposome formulation for cosmetic formulators that
form nano-sized liposomes upon dilution of the
formulation with water using standard mixing devices.
DermasomeTM (NE) is composed of high purity
phospholipids that form stable liposomes with high
encapsulation and incorporation efficiency. The
formulation is colorless and odorless.
DermasomeTM (NE) is composed of a proprietary blend
of unsaturated phospholipids.
Hydration of these lipids with water causes
rearrangement of the lipid bilayers which spontaneously
forms liposomes. If water-soluble active ingredients,
such as peptides, minerals or other water soluble
molecules, are dissolved in water and added to
DermasomeTM (NE), liposomes with high entrapment of
the active molecule are formed. If liposoluble molecules
or antioxidants are added to DermasomeTM (NE) and
hydrated with water, the lipid soluble molecules will be
incorporated into the lipid bilayers of the liposomes. Up
to 65% of a water-soluble molecule in the solution is
encapsulated inside the liposomes and almost 100% of
liposoluble molecules are incorporated into the lipid
bilayers of the liposomes.
Since the lipids that are used in the formulation are
unsaturated, the formulation does not require heating
after hydration. Therefore heat sensitive active
ingredients can be used with DermasomeTM (NE).
INCI NAME
WATER (and) BUTYLENE GLYCOL (and) GLYCERINE (and)
LECITHIN
QUICK FACTS
DermasomeTM products are made
from unsaturated phospholipids and
are used in processes that do not
require heating.
If the active ingredient is
temperature sensitive then use the
DermasomeTM product line.
*NE Stands for non-ethanol based
formulation
6 Cadillac Dr, Suite 245
Brentwood, TN 37027
United States of America
1-(800) 387-0620
info@encapsula.com
/company/encapsula-nanosciences-
llc
DISCLAIMER
Any formulation suggestions or
technical information is based on our
knowledge on the basis of current
scientific data and publications.
Encapsula is only a raw ingredient
manufacturer and cannot accept any
liabilities for products manufactured
by others. Every manufacturer and
formulator is responsible for
compliance with all statutory
regulations including those in the field
of patent legislation.

2. COMPOSITION
Phospholipids 20%
Hydrophilic medium 80%
ANALYTICAL DATA
Peroxide value Max. 1
PH (pur) 5-7
MICROBIOLOGICAL DATA
Yeasts/g absence
Molds/g absence
S. aureus / C. albicans absence
and P. aeruginosa/g
PHYSIO-CHIMICAL PROPERTIES
Appearance: White, milky
Miscibility Form liposomes spontaneously at
Room temperature after addition of
Water.
STORAGE CONDITION
Stable for 24 months in its original closed packaging
below 8℃ (preferred to be kept in refrigerator).
Reclose container immediately after use and protect
from direct sunlight. If container is opened, keep
container in refrigerator at 4℃ and use within 3
months.
REGULATORY STATUS
No specific regulation
PACKAGING
2 oz, 18 oz, 1 Gallon
DERMESOMETM (NE)
QUICK FACTS
DermasomeTM products are made
from unsaturated phospholipids and
are used in processes that do not
require heating.
If the active ingredient is
temperature sensitive then use the
DermasomeTM product line.
*NE Stands for non-ethanol based
formulation
6 Cadillac Dr, Suite 245
Brentwood, TN 37027
United States of America
1-(800) 387-0620
info@encapsula.com
/company/encapsula-nanosciences-
llc
DISCLAIMER
Any formulation suggestions or
technical information is based on our
knowledge on the basis of current
scientific data and publications.
Encapsula is only a raw ingredient
manufacturer and cannot accept any
liabilities for products manufactured
by others. Every manufacturer and
formulator is responsible for
compliance with all statutory
regulations including those in the field
of patent legislation.