This report includes overviews and forecasts of the separations market by product, by company, and by geographic region for the period from 2010 to 2016. The global market is analyzed, and data are provided for each segment.

1. Separation Systems for Commercial Biotechnology
Published:September2011
No.OF Pages:141
Price:US $ 4850
Report Summary
* An overview of the U.S. market for separation systems for commercial
biotechnology
* Analyses of market trends, with data from 2010, estimates for 2011, and
projections of compound annual growth rates (CAGRs) through 2016
* A breakdown of the separation systems for the commercial biotechnology
market into major segments of liquid chromatography, centrifugation,
membrane filtration, electrophoresis, and niche separatio
* Discussion of important technology and the latest advancements in the
industry
* Evaluations of important and upcoming patents
* Company profiles of the top players within the industry.
INTRODUCTION
STUDY GOALS AND OBJECTIVES
This market research report provides a comprehensive sizing, analysis, and
forecast of the global market for the commercial applications of
biotechnology separation systems.
The report will review global markets for biotechnology separation systems
and will forecast trends and sales in these markets through 2016. This
report provides a range of information, including detailed analyses of the
various segments of the market, new applications for separation technology,
and overall industry trends. It examines the separation process for a variety
of biomolecules, including; proteins, RNA, and DNA. This information will
allow the reader to evaluate and quantify the current market size for specific
separation systems within the growing biomedical and pharmaceutical
technology market.
Forecasts and trends have been developed from a variety of data, including
industry sources, company publications, and industry benchmarks. Major

2. separation applications, technologies, geography, and factors influencing the
demand for endoscopy services and products will be discussed.
Consideration is given to an analysis of government issues versus the
biotech and pharmaceutical industry markets.
REASONS FOR DOING THE STUDY
The biomolecule separation market is positioned for significant growth in the
next 5 years. This is due to new protein and other biomolecule products that
will require separation technology, as well as new innovations in the
technology itself. This report investigates one of the major drivers for the
separations system market: the development by the biomedical and
pharmaceutical industry of proteins that can be used as biotherapeutic
agents against a number of human diseases. Another factor that will
contribute to growth is the recognition of this technology in emerging
markets such as Japan and the Pacific Rim countries. Continued global
growth is expected due to a growing middle class in countries such as India,
China, Brazil, and Russia.
This report addresses critically important topics for analyzing a changing
market dynamic; identifies the emerging players; discusses the technologies
and strategies for accessing these emerging markets; and notes the
measurement and forecast of specific segments and geographies to allow for
enhanced resources allocation.
SCOPE OF REPORT
Current and projected protein and biomolecule separation revenue forecasts
during the forecast period (i.e., 2010 to 2016) are discussed. Protein
separation systems are playing important roles in new biopharmaceutical
development. Protein separation systems do not require U.S. Food and Drug
Administration (FDA) approval, but the products produced from these
processes do, and they must be produced in accordance with FDA good
manufacturing practices (GMP) guidelines. Thus, these separation
procedures and equipment must pass FDA audits of the manufacturing
process. New products requiring separation technologies that have been
approved by the FDA in 2009 and 2010 are covered, and those products
expected to be approved within the forecast period are discussed. Due to the
timing of the writing of this report, the figures for 2011 are estimated except
where actual results have been reported
The report includes analysis of the leading competitors, as well as emerging
companies in the current global biomolecule separation market. Profiles of

3. the manufacturers of the leading products are analyzed, and their specific
product strategies are outlined. This report notes companies that are poised
to introduce new products during the forecast period and discusses how
these products may change the face of the competitive environment. This
competitive environment is examined, with a special focus on the ways in
which developing products and technologies are influencing the current
standard of patient care. Detailed profiles of the current market leaders and
emerging companies are discussed in detail.
Market figures are based on revenues at the manufacturers’ level. The base
year for analysis and projection is 2010. Trends are assessed based on a
number of parameters, including projected sales for existing products, new
product introductions, and expanded indications for existing products.
This report also includes overviews and forecasts of the separations market
by product, by company, and by geographic region for the period from 2010
to 2016. The global market is analyzed, and data are provided for each
segment.
Sales figures are reported in U.S. dollars and reflect currency fluctuations
within the performance of revenue change. Revenue figures do not account
for variation in local currencies.
All market share data are presented on a global basis unless specifically
noted.
Table Of Contents
CHAPTER ONE: INTRODUCTION
STUDY GOALS AND OBJECTIVES
REASONS FOR DOING THE STUDY
SCOPE OF REPORT
INTENDED AUDIENCE
METHODOLOGY AND INFORMATION SOURCES
RELATED REPORTS
BCC ONLINE SERVICES
DISCLAIMER
CHAPTER TWO: SUMMARY
SUMMARY
SUMMARY TABLE GLOBAL MARKET FOR COMMERCIAL BIOTECH SEPARATION
SYSTEMS BY METHOD OF SEPARATION, THROUGH 2016 ($ MILLIONS)
SUMMARY FIGURE GLOBAL MARKET FOR COMMERCIAL BIOTECH

4. SEPARATION SYSTEMS BY METHOD OF SEPARATION, 2011 AND 2016 ($
MILLIONS)
CHAPTER THREE: OVERVIEW
BIOMOLECULAR SEPARATION SYSTEMS
TABLE 1 GLOBAL MARKET RANKING FOR COMMERCIAL BIOTECH
SEPARATION SYSTEMS, 2011 AND 2016 (%)
RED BIOTECHNOLOGY
WHITE BIOTECHNOLOGY
GREEN BIOTECHNOLOGY
BLUE BIOTECHNOLOGY
ANALYTICAL, PREPARATIVE, AND PRODUCTION SCALE PROCESSES
ANALYTICAL SCALE SEPARATION PROCESSES
PREPARATIVE SCALE SEPARATIONS
PRODUCTION SCALE SEPARATION
SCOPE
BIOMOLECULAR SEPARATIONS AND PURIFICATION
SEPARATION TECHNOLOGY: CURRENT TRENDS
SEPARATION TECHNOLOGY
TABLE 2 MAJOR COMPANIES IN THE BIOMOLECULAR SEPARATION MARKET
AND MAJOR PRODUCT AREAS, 2011
DRIVERS AND RESISTORS FOR BIOMOLECULAR SEPARATION MARKET
DRIVERS
RESISTORS
COMMERCIAL BIOMOLECULAR SEPARATION MARKET
PROTEINS
ANTIBODIES
ENZYMES
NUCLEIC ACIDS
HORMONES
CELLS
BLOOD AND SERUM PRODUCTS
ORGANIC PRODUCTS
TABLE 3 GLOBAL MANUFACTURE OF BULK CHEMICAL SUBSTANCE BY
BIOCATALYSIS, 2010 (METRIC TONS)
COMMERCIAL SEPARATION SYSTEMS END-USE MARKETS
END USERS OF BIOTECHNOLOGY SEPARATION SYSTEMS
Pharmaceuticals
Food, Cosmetics, and Agriculture
Energy
COMMERCIAL BIOTECHNOLOGY SEPARATION SYSTEMS ENDUSER
DISTRIBUTION WITHIN THE U.S. MARKET
BIOTECHNOLOGY ACTIVITY IN THE U.S.

5. TABLE 4 DISTRIBUTION OF U.S. BIOTECHNOLOGY AND BIOPHARMA
COMPANIES BY REGION, 2008 (%)
DISTRIBUTION OF SEPARATIONS SYSTEMS BY END USERS
OVERVIEW OF THE GLOBAL COMMERCIAL BIOMOLECULAR SEPARATIONS
MARKET
TABLE 5 GLOBAL MARKET FOR BIOMOLECULAR SEPARATIONS SYSTEMS
INDUSTRY BY REGION, THROUGH 2016 ($ MILLIONS)
OVERVIEW OF GLOBAL MARKET SEPARATION SYSTEMS GROWTH BY
SEPARATION METHOD
TABLE 6 GLOBAL MARKET FOR SEPARATION SYSTEMS BY SEPARATION
METHOD, THROUGH 2016 ($ MILLIONS)
SEPARATION SYSTEMS MARKET: COMPETITIVE STRUCTURE
TABLE 7 COMPETITIVE STRUCTURE, 2010
DISTRIBUTION STRUCTURE
KEY END USERS
MERGERS AND ACQUISITIONS
TABLE 8 ACQUIRED BIOTECHNOLOGY AND BIOPHARMACEUTICAL
COMPANIES, 2008-2010 ($ MILLIONS)
CHAPTER FOUR: CENTRIFUGATION SYSTEMS IN BIOTECHNOLOGY
CENTRIFUGATION SYSTEMS IN BIOTECHNOLOGY
TABLE 9 CENTRIFUGATION PROCESSES AND CHEMICALS USED
TYPES OF CENTRIFUGATION PROCEDURES
APPLICATIONS OF CENTRIFUGATION IN SEPARATION
APPLICATIONS OF CENTRIFUGATION SYSTEMS IN THE BIOTECH INDUSTRY
DRIVERS FOR CENTRIFUGATION SYSTEMS IN THE BIOTECH INDUSTRY
TABLE 10 GLOBAL MARKET FOR CENTRIFUGATION SEPARATION SYSTEMS
BY REGION, THROUGH 2016 ($ MILLIONS)
TABLE 11 CENTRIFUGATION SEPARATION SYSTEMS MARKET, THROUGH
2016 ($ MILLIONS)
TABLE 12 PRODUCT TECHNOLOGY IN ULTRACENTRIFUGATION BY
COMPANY, 2011
KEY PLAYERS IN THE CENTRIFUGATION SEPARATION SYSTEMS GLOBAL
MARKET
CHAPTER FIVE: LIQUID CHROMATOGRAPHY IN BIOMOLECULAR
SEPARATIONS IN BIOTECHNOLOGY
LIQUID CHROMATOGRAPHY…
TABLE 13 PRODUCT TECHNOLOGY IN CHROMATOGRAPHY BY COMPANY,
2011
ION EXCHANGE CHROMATOGRAPHY
GEL FILTRATION CHROMATOGRAPHY
AFFINITY CHROMATOGRAPHY

6. THIN-LAYER CHROMATOGRAPHY
FLASH CHROMATOGRAPHY
HIGH-PERFORMANCE, THIN-LAYER CHROMATOGRAPHY
APPLICATIONS OF LIQUID CHROMATOGRAPHY IN THE GLOBAL
BIOMOLECULAR SEPARATIONS INDUSTRY
LIFE SCIENCES
PHARMACEUTICAL DEVELOPMENT
CLINICAL
FOOD AND FLAVOR
DRIVERS OF LIQUID CHROMATOGRAPHY IN THE BIOMOLECULAR
SEPARATION INDUSTRY
MARKET ANALYSIS OF THE GLOBAL LIQUID CHROMATOGRAPHY BIOTECH
INDUSTRY THROUGH 2011
TABLE 14 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY SYSTEMS BY
REGION, THROUGH 2016 ($ MILLIONS)
TABLE 15 GLOBAL MARKET FOR CHROMATOGRAPHY SYSTEMS BY
TECHNOLOGY, THROUGH 2016 ($ MILLIONS)
TABLE 16 KEY PLAYERS IN THE LIQUID CHROMATOGRAPHY SEPARATION
SYSTEMS MARKET, 2010
CHAPTER SIX: ELECTROPHORESIS IN BIOMOLECULAR SEPARATIONS
TYPES OF ELECTROPHORESIS
GEL ELECTROPHORESIS
Two-Dimensional Gel Electrophoresis
CAPILLARY ELECTROPHORESIS
Capillary Gel Electrophoresis
Capillary Isoelectric Focusing
Capillary Electro-Chromatography
DIELECTROPHORESIS
FREE-FLOW ELECTROPHORESIS
APPLICATION OF ELECTROPHORESIS IN THE BIOMOLECULAR SEPARATIONS
INDUSTRY
DRIVERS OF ELECTROPHORESIS IN THE BIOMOLECULAR SEPARATIONS
INDUSTRY
MARKET ANALYSIS OF GLOBAL ELECTROPHORESIS BIOMOLECULAR
SEPARATIONS
TABLE 17 GLOBAL MARKET FOR ELECTROPHORESIS SYSTEMS BY REGION,
THROUGH 2016 ($ MILLIONS)
TABLE 18 GLOBAL MARKET FOR ELECTROPHORESIS SYSTEMS BY METHOD,
THROUGH 2016 ($ MILLIONS)
KEY PLAYERS IN ELECTROPHORESIS SEPARATION SYSTEMS GLOBAL
MARKET

7. CHAPTER SEVEN: MEMBRANE FILTRATION IN BIOMOLECULAR
SEPARATIONS
MATERIAL COMPOSITION OF MEMBRANE FILTERS
TABLE 19 CLASSES OF FILTRATION BY PORE SIZE AND APPLICATION
CROSS-FLOW AND TANGENTIAL FLOW FILTRATION
BIOMOLECULAR FILTRATION CONFIGURATIONS
CERAMIC MEMBRANES
PLASTIC-IRRADIATED-ETCHED FILTERS
ADVANTAGES OF MEMBRANE SYSTEMS
DISADVANTAGES OF MEMBRANE SYSTEMS
APPLICATION OF MEMBRANE FILTRATION TO THE BIOMOLECULAR
SEPARATIONS INDUSTRY
APPLICATIONS IN THE BIOPHARMA INDUSTRY
CURRENT TRENDS
DRIVERS OF MEMBRANE FILTRATION IN THE BIOMOLECULAR SEPARATIONS
INDUSTRY
HIGH DEMAND FOR PROTEIN SEPARATION
HIGH QUALITY AND YIELD
LOW OVERALL COSTS
MARKET ANALYSIS OF MEMBRANE FILTRATION IN THE BIOMOLECULAR
SEPARATIONS INDUSTRY THROUGH 2016
TABLE 20 GLOBAL MARKET FOR MEMBRANE FILTRATION SYSTEMS BY
REGION, THROUGH 2016 ($ MILLIONS)
KEY PLAYERS IN THE GLOBAL MARKET FOR MEMBRANE FILTRATION
SEPARATION SYSTEMS
CHAPTER EIGHT: NEW METHODS OF BIOMOLECULAR SEPARATION
MICROARRAY AND LAB-ON-A-CHIP
MICROARRAYS
BIOCHIPS
LAB-ON-A-CHIP
FLOW CYTOMETRY
CLINICAL APPLICATIONS OF FLOW CYTOMETER
MAGNETIC SEPARATION
TABLE 21 GLOBAL MARKET FOR NEW SEPARATION METHODS BY REGION,
THROUGH 2016 ($ MILLIONS)
TABLE 22 MARKET FOR NEW SEPARATIONS METHODS, THROUGH 2016 ($
MILLIONS)
TABLE 23 KEY PLAYERS IN EACH OF THE NEW SEPARATIONS MARKET
SEGMENTS
CHAPTER NINE: COMPANY PROFILES
AFFYMETRIX

8. AGILENT TECHNOLOGIES
ALFA LAVAL GROUP
ALFA WASSERMANN SEPARATION TECHNOLOGIES
APPLIED BIOSYSTEMS CORPORATION
BECKMAN COULTER, INC.
BD BIOSCIENCES (BECTON, DICKINSON, AND COMPANY)
BIO-RAD LABORATORIES, INC.
CALIPER LIFE SCIENCES
DIONEX
FLOTTWEG SEPARATIONS TECHNOLOGY
GE HEALTHCARE LIFE SCIENCES
HITACHI KOKI CO., LTD.
INVITROGEN
LIFE TECHNOLOGIES
MILLIPORE BIOMANUFACTURING AND LIFE SCIENCES (MERCK KGAA)
NOVASEP LIFE SCIENCES MANUFACTURING SOLUTIONS
PALL CORPORATION
PERKIN-ELMER
QIAGEN GMBH
SEPMAG TECHNOLOGIES
SARTORIUS STEDMAN BIOTECH CORPORATION
SHIMADZU SCIENTIFIC INSTRUMENTS
TECAN GROUP, LTD.
THERMO FISHER SCIENTIFIC
WATERS CORPORATION
WHATMAN INTERNATIONAL, LTD.
CHAPTER TEN: PATENTS FOR BIOMOLECULAR
SEPARATIONSRELATED INSTRUMENTATION AND ACCESSORIES
TABLE 24 PATENTS ISSUED FOR BIOMOLECULAR SEPARATIONS
TECHNOLOGIES, 2005-2010
TABLE 25 U.S. AND E.U. BIOMOLECULAR SEPARATIONS PATENTS BY AREA
(%)
TABLE 26 BIO-RAD LABORATORIES PARTIAL U.S. PATENT LIST
TABLE 27 AGILENT TECHNOLOGIES PARTIAL U.S. PATENT LIST
TABLE 28 GE HEALTHCARE LIFE SCIENCES PARTIAL U.S. PATENT LIST
TABLE 29 WATERS CORPORATION PARTIAL U.S. PATENT LIST
TABLE 30 MERCK MILLIPORE CORPORATION PARTIAL U.S. PATENT LIST
TABLE 31 GLOBAL CHROMATOGRAPHY PATENTS
TABLE 32 MEMBRANE FILTRATION PATENTS
TABLE 33 ELECTROPHORESIS PATENTS

9. APPENDIX
TABLE 34 KEY WEBSITES
TABLE 35 KEY INDUSTRY AND REGULATORY ASSOCIATIONS
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