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DNA
DNA It’s gonna getchoo.
The basics
Space-filling Model
Super-simplified
DNA in the cell
Transcription
Transcription
Translation
Or you can watch it . . .
Junk DNA?
Junk DNA?
Tandem Repeats ,[object Object]
Tandem Repeats
RFLP
RFLP
RFLP
Gel Electrophoresis
PP doesn’t like flash . . .  ,[object Object]
A run gel.
DNA RFLP Comparison
BUT . . .
BUT . . .  ,[object Object]
BUT . . .  ,[object Object],[object Object]
BUT . . .  ,[object Object],[object Object],[object Object]
BUT . . .  ,[object Object],[object Object],[object Object],[object Object]
BUT . . .  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Short Tandem Repeats
Short Tandem Repeats We are a type of  tandem repeat . . .
Short Tandem Repeats We are a type of  tandem repeat . . .  BUT TINY!
The 13 CODIS STR’s and their Identity Probabilities STR African American U.S. Caucasian D3S1358 0.094 0.075 vWA 0.063 0.062 FGA 0.033 0.036 TH01 0.109 0.081 TPOX 0.090 0.195 CSF1PO 0.081 0.112 D5S818 0.112 0.158 D13S317 0.136 0.085 D7S820 0.080 0.065 D8S1179 0.082 0.067 D21S11 0.034 0.039 D18S51 0.029 0.028 D16S539 0.070 0.089
Fortunately!

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Dna presentation

Hinweis der Redaktion

  1. For example, each human cell has about 1.8 meters of DNA, but wound on the histones it has about 90 micrometers (0.09 mm) of chromatin, which, when duplicated and condensed during mitosis , result in about 120 micrometers of chromosomes .
  2. You only need 1x10-9 g of DNA to PCR the STRs to make an identification.