Presentation by Michelle Longmire, CEO of Medable, April 20, 2021, for mHealth Israel. During CoVID, as physical access to clinics was limited, Medable enabled patients to continue participating in critical research efforts. Medable Supporting over 100 Studies Across a Diverse Array of Therapeutic Areas. Medable provides a platform for seamless evidence generation, across the entire patient journey. Connecting patients globally for community, care, and research. Improve patient experience and retention. Reduce site burden. Data Cloud & Platform should be flexible and modular to enable protocol-fit digital. Medable Digitome, for data driven decentralized trials and a new era of understanding patients, therapies, and conditions. Clinical research is a small component of the broader healthcare journey. Enable health data and evidence generation from clinical to commercial, from day one. Continuous health data & evidence from clinical to commercial and beyond. The Digitome can provide a primary observational protocol that collects large scale baseline data in a framework that enables streamlined recruitment, enrollment, and participation into interventional clinical substudies.

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Our Mission- -
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Get effective therapies to
patients faster.
Goal: Reduce trial
timelines by 50%
Dr. Michelle Longmire
CEO & Co-founder

2. Decentralized Research has gone from edge case to main case
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37% of sites fail to meet enrollment targets
10% of sites fail to recruit a single patient
35% of patients drop-out
Patients can access research from anywhere in the world
Enrollment accelerated 3x TA’s & phases
Massive adoption of patient-centered technologies
2020: The year of
decentralized research
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3. 86,726
Patients
3,555
Clinics
engaged
As Physical Access to Clinics was Limited, Medable Enabled Patients
to Continue Participating in Critical Research Efforts
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4. Medable Supporting over 100 Studies Across
a Diverse Array of Therapeutic Areas
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Medable DCT platform
>72%
Of Medable DCT’s in
phase II & III
*Breakdown of therapeutic areas
across the Medable portfolio

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Medable provides a platform for seamless evidence
generation, across the entire patient journey
By connecting with patients directly, we are driving an
era research that unifies processes and data across
the entire patient healthcare journey
Trial-ready Patient
Community
Recruitment &
Enrollment
Digital
Clinical Trial
Commercial
Digital
Go-to-Market

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Reduce site burden
● Insights into their patients with remote patient monitoring
● Sites can engage with patients virtually to reduce burden
● Designed for clinician workflow = increased data quality
Patient App
(Axon)
Site App
(Axon)
Connecting patients globally for community, care, and research
A single platform to connect all patient and site data
Product
Platform
Process &
Partnership
eRecruitment
eScreening
ePRO & diaries
eConsent
Remote Patient
Monitoring
Telemedicine
eCOA
Wearables &
Devices
Improve patient experience and retention
● One seamless experience across the trial for patients
● Integrates devices and sensors to reduce burden
● Engaged patients with communication to providers
Configurable platform
applications
Patients
Sites

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Medable is flexible and modular to enable protocol-fit digital
External Data
EDC
Digitome
IRT
Internal Systems
External Systems
MEDABLE Patient +
Site App Data
Patient Community
eConsent
eCOA
Connected Device
Image|Video|Voice
Virtual Screening
Data sources
Rapid feedback for Patients
Better insights & support for Sites
Access and actionable insights for
Clinical Teams
Patients
Clinical teams
Sites
Benefits
MEDABLE Data Cloud & Platform
Tools & Services
Secure database
HIPAA | HITRUST | GDPR | 21 CFR Part 11
Real-time
Analytics
Data Visualization AI / ML APIs
Ingest, Harmonize & Map

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Medable delivers seamless experiences for patients
A single platform to connect all patient data
Global | Scalable | Configurable
One seamless experience for patients

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D I G I T O M E
Introducing Medable Digitome, for data driven decentralized trials
and a new era of understanding patients, therapies, and conditions
Trial Design &
Feasibility
Recruitment &
Enrollment
Evidence
Generation
Submission &
Post-marketing
Surveillance
BIO
SOCIAL
MEDIA
GENOMIC
S
EPIDEMIOLOGY
IMAGING
CTMS
GENETIC
SENSOR
EMR
CLAIMS
RX
LAB
DRUG PATHWAY TRIALS MOLECULAR
REGISTRIES

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Trial-Ready Digitome Communities
The Digitome can provide a
primary observational protocol
that collects large scale baseline
data in a framework that enables
streamlined recruitment,
enrollment, and participation into
interventional clinical substudies.
Accelerate
● Recruitment
● Enrollment
● Study Deployment/Start-up
● Evidence Generation

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Clinical research is a small component of the broader healthcare
journey
Diagnosis Post-Trial
Healthcare
Clinical
Trial
Adjacent
Healthcare
Pre-Diagnosis Initial
Treatment
Doctor visits
Lab tests
Imaging test
Medications
Medable Digitome provides continuous health data & evidence
from clinical to commercial and beyond

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Medable Digitome, enable health data and evidence generation
from clinical to commercial, from day one
EMR
Labs Claims
Devices
Genomics
Imaging
Outcome
Rx

13. P R E S E N T A T I O N F O R