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Ion Therapy: A More Effective Way to Treat Cancer
1. “The International
Agency for
Research on
Cancer projects
that by 2030
almost
21.4 million new
cases will be
diagnosed
annually…..”
http://www.cbc.ca/health/story/2010/06
/02/cancer-world-statistics.html
Lester Lin ver. 1 10/4/2012
2. An simple primer on various
treatments for cancer such as Photons,
Protons, and Carbon ions.
Lester Lin v7 10/4/2012
3. Every year, 10’s of millions of people will
hear these words from their doctor.
You
Have
Cancer
Lester Lin ver. 1 10/4/2012
4. Typical cancer treatments:
Chemotherapy
Controlled poisoning of your body
Terrible side effects.
Hair loss
Nausea
Digestive tract
Surgery
Invasive
Risk of infection
Damage to critical tissue
Scarring
Side effects such as impotence and incontinence for prostate
cancer as an example.
Lester Lin ver. 1 10/4/2012
5. Typical cancer treatments:
X-ray
Radiation
Therapy.
Exposure of healthy
tissue to radiation
Negative Side effects
Cancer
X-Ray Radiation bombarding tumor Tumor
Lester Lin ver. 1 10/4/2012
6. Proton P
Therapy
Protons are
propelled through
an accelerator at
50% of the speed of
light, then shot into
the patient’s body
aimed precisely at
the tumor.
Cancer
Tumor
Lester Lin ver. 1 10/4/2012
7. Proton P The Bragg Peak describes the characteristic of
protons and ions to have a peak release in
energy right before it comes to rest. This
Therapy accounts for the amazing power to kill cancer
cells, while minimizing bad radiation exposure to
healthy tissue.
There are
only 30
Proton Therapy
Centers around
the world.
Cancer
Tumor
Lester Lin ver. 1 10/4/2012
8. X-Rays expose the healthy
tissue to maximum power,
then decreases in energy on
the way to the tumor. After
the tumor, the energy is still
dissipating, and irradiating
healthy tissue distally to the
tumor.
Protons are going through
healthy tissue at very low
radiation levels and at high
speed, then reaches peak
power at the tumor,
delivering peak killing power.
The radiation level then drops
off very quickly causing little
damage to healthy tissue
distally..
Carbon Ions also have the Bragg Peak traits, but delivered at over 20x’s
the power of protons. Lester Lin ver. 1 10/4/2012
9. Control Ion
Pre-Linear Synchrotron
System Source C Accelerator Accelerator
How Ions are shot.
The Ion Source produces carbon ions and
feeds it to the
Pre-Linear Accelerator which accelerates
the carbon ions and feeds it to Beam
Line
The Synchrotron Accelerator which
speeds the carbon ions to 70% the speed
of light and shoots them through the
Beam Line to the
The Gantry, which aims these high speed
carbon ions at the patient’s cancerous Gantry
tumor Treatment
Couch and
Chair
while the patient is held very still in the
Treatment Couch or chair to ensure
maximum possible accuracy. Lester Lin ver. 1 10/4/2012
10. Control Ion Synchrotron
System Source C Pre-Linear
Accelerator Accelerator
Beam
Line
The ions rapidly peak in
energy when arriving at
the tumor and deliver Cancer
Gantry
Tumor
the killing power.
Lester Lin ver. 1 10/4/2012
11. Carbon Ion Therapy vs. Proton Therapy
Bragg Peak Systems, Inc.: A company that will build
FDA approved Heavy Ion Therapy Systems.
Protons come
from Hydrogen
molecules.
P
Carbon ions Carbon
come from
Carbon molecules.
Many times, these
are referred to as
“Heavy Ions”
because they are 20x’s
12x’s heavier than the
protons, and cancer
much more killing
effective than energy
protons against of
cancer. Protons
Lester Lin ver. 1 10/4/2012
12. P
•An angry wild elephant
is charging at you.
•Do you want the gun on Carbon
the left?
•or the one on the right to
protect you?
•The small gun can kill
an elephant.
• But the big one will do it 20 x’s
faster and more the
efficiently. cancer
killing
•Elephant = cancer. energy
•Protons = small gun of
•Carbon Ions = BIG gun. Protons Lin ver. 1
Lester 10/4/2012
13. Protons typically deliver single breaks of
DNA strands, which leaves a chance for
cancer cells to repair themselves.
P
P
P
P
Lester Lin ver. 1 10/4/2012
14. Carbon Ions deliver massive double
strand breaks of DNA in the cancer
Carbon
cells, making it impossible for them
to repair themselves.
Lester Lin ver. 1 10/4/2012
15. X-Ray Radiation: Good
Proton Therapy: Better
Carbon Ion Therapy: Best
Carbon Ions have shown the ability to kill tumors with
2 to 40x’s less treatment sessions than with Protons.
Consider what that means to a cancer victim.
Full treatments finished in 10 days instead of 40*
Less stress, and less “downtime” for the patient.
Less unnecessary exposure of healthy cells to radiation.
Financial savings for less travel and lodging during treatments,
and less work missed
Lester Lin ver. 1 10/4/2012
16. 4 room Proton Center compared to 4 room Carbon Ion Center
1 year time frame each administering 36,000 sessions.
1 year comparison forecast of cured patients finishing treatments between a 4 room
Carbon-Ion vs. Proton Center
4000
3500
3000
Protons Carbon Ion
2500 900 patients 3,600 patients
completing completing
2000 treatments in treatments in
one year. one year.
1500
•Higher Revenue
1000 •More Patients
Treated.
500
0
Cured Patients Treatments x10
Proton Carbon-ion
2.5 patients per hour-12hrs. Per day-300 days per year. Avg. 40 total proton treatments vs. 10 total carbon treatments
Lester Lin ver. 1 10/4/2012
17. 4 room Proton Center compared to 4 room Carbon Ion Center
25 year time frame
25 year comparison forecast of cured patients finishing treatments between a 4 room
Carbon-Ion vs. Proton Center
4000
3500
Over the next 25 years… let’s examine the long term effect:
If you go with Protons, 67,500 less people will get treated for their cancer
3000
from your center.
2500
A Heavy Ion center, charging the same price to complete cancer treatments as
2000
a Proton center should generate 400 to 1000% more profit.
On 1500 basis, compare generating 45 million USD yearly revenue as a Proton
this
center, (just for Proton treatments) or 180 million USD as a Heavy Ions
Center… or how about DOUBLE THAT??? (which is a possibility)
1000
Over 25 years,
500
1.125 billion vs. 4.5 billion USD
0
Treated Patients Treatments x10
Proton Carbon-ion
2.5 patients per hour-12hrs. Per day-300 days per year. Avg. 40 total proton treatments vs. 10 total carbon treatments
Lester Lin ver. 1 10/4/2012
18. The Bragg Peak Systems
business plan is to build a
160 million USD product
with only 17 million of start-
up capital, and no debt.
Boeing invested over
2 billion USD to develop the
747 in the 1960’s to produce
a product that sold for Bragg Peak will produce the Heavy
22 million USD each. Ion System with FDA approval in 4
years starting from the completion of
http://www.centennialofflight.gov/essay/Aerospa
ce/Boeing_747/Aero21.htm funding.
Lester Lin v7 10/4/2012 18
19. Each year, an enemy on
American soil kills over
550,000 Americans, and
takes over 1.5 million new
hostages. the enemy is
CANCER
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20. The National Missile Defense
Program:
The projected cost of the program for
the years 2004 to 2009 will be
$53,000,000,000 USD (53
billion) for protection.
We ask for investor
participation of just $17
million USD to bring the best
proven weapon against cancer
into a reality.Lester Lin v7 20
10/4/2012
21. C C
C C
$50,000 USD
Carbon Ion C C
Treatment fee
C C
C C
10 Treatments in 2 Weeks @ $5,000 USD ea. = $50,000
40 Treatments in 8 Weeks @ $1,250 USD ea. = $50,000
P P P P P P P P
P P P P P P P P
$50,000 USD
P P P P P P P P
Proton
Treatment fee
P P P P P P P P
P P P P P P P P
Lester Lin ver. 1 10/4/2012
22. C Benefits for the Patient
•Saved 7 weeks of time
C •Saved 7 weeks of lodging expenses
$50,000 USD •Saved 7 weeks of lost work-time
Carbon Ion C •Reduced the stress of treatment by 7 weeks.
Treatment fee
C Benefits for the Medical Center
•1000% more revenue per treatment.
•Up to 10x’s more patients cured in equal time period.
4 C Treatments in 1 Week @ $12,500 USD ea. = $50,000
40 P Treatments in 8 Weeks @ $1,250 USD ea. = $50,000
P P P P P P P P
P P P P P P P P
$50,000 USD
P P P P P P P P
Proton
Treatment fee
P P P P P P P P
P P P P P P P P
Lester Lin ver. 1 10/4/2012
23. The future of treating a cancer patient at
a much lower price point than current
fees can be accomplished with Heavy Ion
Therapy.
This is of prime importance for countries
with national health insurance.
24. 2011 Medipolis, Japan
2012? Pavia, Italy
2012 Kiel, Germany
History and Plans of 2013 Shizuoka, Japan
Heavy Ion Centers Opening. 2014 Zhuhai , China
2014? Shanghai, China
2014? South Africa
2014? Austria CC
Over 8,000 patients treated CC
with Carbon Ions by 2010! C
CC
2009 Heidleberg Germany
2010 Marburg Germany
2010 Gunma , Japan
C
C
CC
Main stream phase
2002 Hyogo Japan Carbon Ions are entering
C the mainstream clinical
1997 GSI Germany
usage phase with
1994: Chiba, Japan C rapid acceleration of
C Proving Heavy Ion Centers
phase opening.
25. 2011 Medipolis, Japan
5 years from now, Proton Centers 2012? Pavia, Italy
will be fighting the stigma of being 2012 Kiel, Germany
“YESTERDAY’S” technology. 2013 Shizuoka, Japan
2014 Zhuhai , China
2014? Shanghai, China
Planners and decision
makers will be 2014? South Africa
questioned, Why 2014? Austria
C C
didn’t they see this
trend coming??
Over 8,000 patients treated CC
with Carbon Ions by 2010! C
CC
2009 Heidleberg Germany
2010 Marburg Germany
2010 Gunma , Japan
C
C
CC
2002 Hyogo Japan
5 years from now, those
1997 GSI Germany
C who had the foresight to
go with Carbon Ions
1994: Chiba, Japan C today, will be admired as
C Proving
the strategic thinkers and
Stage
planners tomorrow.
26. • Deliver 20x’s the cancer killing power of
The Bragg Peak Systems
Protons.
Medical Advantage
• Cure the Patient 4 to 10x’s faster
• Financial earning potential over a Proton Center is
The Bragg Peak Systems staggering.
Financial Advantage • Proton’s will find it hard to compete with Heavy Ion
Centers in the future.
• Shorter treatment times potentially 4 to 10x’s less.
The Bragg Peak Systems • Less Stress for the patient Physically, Emotionally and
Benefit to the Patient Financially.
• Less unnecessary radiation exposure.
• A Heavy Ion Center will provide maximum advantage
The Bragg Peak Systems to the general public by having the capability to treat
Benefit to Society many multiples more patients than a Proton center
with the same number of treatment rooms.
Lester Lin ver. 1 10/4/2012
27. The only company offering an
upgradable Proton Therapy System
The only company with a
firm commitment to deliver an
FDA approved system from the onset.
Bringing Heavy Ion systems to market
at an affordable price point.
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28. We hope you have caught our vision and inspiration and
choose Bragg Peak Systems as your partner for your FDA
approved Particle Treatment System.
With all sincerity, the team from
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