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“The International
Agency for
Research on
Cancer projects
that by 2030
almost
21.4 million new
cases will be
diagnosed
annually…..”
http://www.cbc.ca/health/story/2010/06
/02/cancer-world-statistics.html




                                         Lester Lin ver. 1   10/4/2012
An simple primer on various
treatments for cancer such as Photons,
Protons, and Carbon ions.




                       Lester Lin v7   10/4/2012
Every year, 10’s of millions of people will
hear these words from their doctor.



   You
   Have
   Cancer

                                  Lester Lin ver. 1   10/4/2012
 Typical cancer treatments:

    Chemotherapy
        Controlled poisoning of your body
        Terrible side effects.
        Hair loss
        Nausea
        Digestive tract



   Surgery
        Invasive
        Risk of infection
        Damage to critical tissue
        Scarring
        Side effects such as impotence and incontinence for prostate
         cancer as an example.
                                             Lester Lin ver. 1   10/4/2012
Typical cancer treatments:

 X-ray
   Radiation
   Therapy.
    Exposure of healthy
     tissue to radiation
    Negative Side effects



                                   Cancer
X-Ray Radiation bombarding tumor   Tumor



                                            Lester Lin ver. 1   10/4/2012
 Proton          P



 Therapy
 Protons are
 propelled through
 an accelerator at
 50% of the speed of
 light, then shot into
 the patient’s body
 aimed precisely at
 the tumor.

                         Cancer
                         Tumor



                                  Lester Lin ver. 1   10/4/2012
 Proton   P   The Bragg Peak describes the characteristic of
               protons and ions to have a peak release in
               energy right before it comes to rest. This
 Therapy       accounts for the amazing power to kill cancer
               cells, while minimizing bad radiation exposure to
               healthy tissue.
                                                     There are
                                                     only 30
                                                     Proton Therapy
                                                     Centers around
                                                     the world.




                              Cancer
                              Tumor



                                       Lester Lin ver. 1   10/4/2012
X-Rays expose the healthy
tissue to maximum power,
then decreases in energy on
the way to the tumor. After
the tumor, the energy is still
dissipating, and irradiating
healthy tissue distally to the
tumor.

Protons are going through
healthy tissue at very low
radiation levels and at high
speed, then reaches peak
power at the tumor,
delivering peak killing power.
The radiation level then drops
off very quickly causing little
damage to healthy tissue
distally..

Carbon Ions also have the Bragg Peak traits, but delivered at over 20x’s
the power of protons.                            Lester Lin ver. 1 10/4/2012
Control              Ion
                                               Pre-Linear                             Synchrotron
     System              Source   C           Accelerator                             Accelerator




How Ions are shot.
The Ion Source produces carbon ions and
feeds it to the
Pre-Linear Accelerator which accelerates
the carbon ions and feeds it to                                                             Beam
                                                                                            Line


The Synchrotron Accelerator which
speeds the carbon ions to 70% the speed
of light and shoots them through the
Beam Line to the

The Gantry, which aims these high speed
carbon ions at the patient’s cancerous                                                      Gantry

tumor                                                   Treatment
                                                        Couch and
                                                          Chair
while the patient is held very still in the
Treatment Couch or chair to ensure
maximum possible accuracy.                                  Lester Lin ver. 1   10/4/2012
Control        Ion                                                    Synchrotron
System        Source   C      Pre-Linear
                             Accelerator                              Accelerator




                                                                           Beam
                                                                            Line




The ions rapidly peak in
energy when arriving at
the tumor and deliver      Cancer
                                                                         Gantry
                           Tumor
the killing power.
                                      Lester Lin ver. 1   10/4/2012
 Carbon Ion Therapy vs. Proton Therapy
     Bragg Peak Systems, Inc.: A company that will build
     FDA approved Heavy Ion Therapy Systems.
            Protons come
            from Hydrogen
            molecules.
      P
            Carbon ions            Carbon
            come from
            Carbon molecules.
            Many times, these
            are referred to as
            “Heavy Ions”
            because they are          20x’s
            12x’s heavier than         the
            protons, and              cancer
            much more                 killing
            effective than           energy
            protons against             of
            cancer.                  Protons
                                          Lester Lin ver. 1   10/4/2012
P
    •An angry wild elephant
    is charging at you.

    •Do you want the gun on        Carbon
    the left?
    •or the one on the right to
    protect you?

    •The small gun can kill
    an elephant.
    • But the big one will do it   20 x’s
    faster and more                  the
    efficiently.                    cancer
                                    killing
    •Elephant = cancer.            energy
    •Protons = small gun              of
    •Carbon Ions = BIG gun.        Protons Lin ver. 1
                                         Lester         10/4/2012
Protons typically deliver single breaks of
DNA strands, which leaves a chance for
   cancer cells to repair themselves.




           P
                P


                                           P



                        P



                            Lester Lin ver. 1   10/4/2012
Carbon Ions deliver massive double
strand breaks of DNA in the cancer
                                       Carbon
cells, making it impossible for them
        to repair themselves.




                                       Lester Lin ver. 1   10/4/2012
X-Ray Radiation: Good
         Proton Therapy: Better
                 Carbon Ion Therapy: Best
 Carbon Ions have shown the ability to kill tumors with
  2 to 40x’s less treatment sessions than with Protons.

   Consider what that means to a cancer victim.

   Full treatments finished in 10 days instead of 40*

   Less stress, and less “downtime” for the patient.

   Less unnecessary exposure of healthy cells to radiation.

   Financial savings for less travel and lodging during treatments,
    and less work missed
                                           Lester Lin ver. 1   10/4/2012
4 room Proton Center compared to 4 room Carbon Ion Center
     1 year time frame each administering 36,000 sessions.

                 1 year comparison forecast of cured patients finishing treatments between a 4 room
                                            Carbon-Ion vs. Proton Center
     4000



     3500



     3000

                            Protons                                                  Carbon Ion
     2500                 900 patients                                            3,600 patients
                          completing                                                completing
     2000                treatments in                                             treatments in
                           one year.                                                  one year.
     1500
                                                                                 •Higher Revenue
     1000                                                                         •More Patients
                                                                                      Treated.
      500



        0
                                             Cured Patients         Treatments x10
                                   Proton                                                Carbon-ion
  2.5 patients per hour-12hrs. Per day-300 days per year. Avg. 40 total proton treatments vs. 10 total carbon treatments
                                                                           Lester Lin ver. 1   10/4/2012
4 room Proton Center compared to 4 room Carbon Ion Center
                    25 year time frame

                 25 year comparison forecast of cured patients finishing treatments between a 4 room
                                            Carbon-Ion vs. Proton Center
     4000



     3500
 Over the next 25 years… let’s examine the long term effect:
 If you go with Protons, 67,500 less people will get treated for their cancer
     3000
 from your center.
     2500

 A Heavy Ion center, charging the same price to complete cancer treatments as
    2000
 a Proton center should generate 400 to 1000% more profit.
 On 1500 basis, compare generating 45 million USD yearly revenue as a Proton
     this
 center, (just for Proton treatments) or 180 million USD as a Heavy Ions
 Center… or how about DOUBLE THAT??? (which is a possibility)
     1000

 Over 25 years,
      500
 1.125 billion vs. 4.5 billion USD
        0
                                            Treated Patients        Treatments x10
                                   Proton                                                Carbon-ion
  2.5 patients per hour-12hrs. Per day-300 days per year. Avg. 40 total proton treatments vs. 10 total carbon treatments
                                                                           Lester Lin ver. 1   10/4/2012
The Bragg Peak Systems
business plan is to build a
160 million USD product
with only 17 million of start-
up capital, and no debt.

Boeing invested over
2 billion USD to develop the
747 in the 1960’s to produce
a product that sold for                           Bragg Peak will produce the Heavy
22 million USD each.                              Ion System with FDA approval in 4
                                                  years starting from the completion of
http://www.centennialofflight.gov/essay/Aerospa
ce/Boeing_747/Aero21.htm                          funding.
                                                           Lester Lin v7   10/4/2012      18
Each year, an enemy on
  American soil kills over
 550,000 Americans, and
takes over 1.5 million new
        hostages.                      the enemy is

                                       CANCER

                       Lester Lin v7   10/4/2012      19
The National Missile Defense
Program:

The projected cost of the program for
the years 2004 to 2009 will be
$53,000,000,000 USD (53
billion) for protection.


We ask for investor
participation of just $17
million USD to bring the best
proven weapon against cancer
into a reality.Lester Lin v7  20
                               10/4/2012
C   C
                C   C
$50,000 USD
  Carbon Ion    C   C
Treatment fee
                C   C
                C   C
 10 Treatments in 2 Weeks @ $5,000 USD ea. = $50,000
 40 Treatments in 8 Weeks @ $1,250 USD ea. = $50,000

                P   P   P   P   P   P        P         P

                P   P   P   P   P   P        P         P
$50,000 USD
                P   P   P   P   P   P        P         P
   Proton
Treatment fee
                P   P   P   P   P   P        P         P

                P   P   P   P   P   P        P         P
                                        Lester Lin ver. 1   10/4/2012
C       Benefits for the Patient
                         •Saved 7 weeks of time
                 C       •Saved 7 weeks of lodging expenses
$50,000 USD              •Saved 7 weeks of lost work-time
  Carbon Ion     C       •Reduced the stress of treatment by 7 weeks.
Treatment fee
                 C       Benefits for the Medical Center
                         •1000% more revenue per treatment.
                         •Up to 10x’s more patients cured in equal time period.

4    C   Treatments in 1 Week @ $12,500 USD ea. = $50,000
40   P    Treatments in 8 Weeks @ $1,250 USD ea. = $50,000

                 P   P     P     P    P     P        P         P

                 P   P      P    P    P     P        P         P
$50,000 USD
                 P   P     P     P    P     P        P         P
   Proton
Treatment fee
                 P   P      P    P    P     P        P         P

                 P   P      P    P    P     P        P         P
                                                Lester Lin ver. 1   10/4/2012
The future of treating a cancer patient at
a much lower price point than current
fees can be accomplished with Heavy Ion
Therapy.

This is of prime importance for countries
with national health insurance.
2011    Medipolis, Japan
                                                       2012?   Pavia, Italy
                                                       2012    Kiel, Germany
   History and Plans of                                2013    Shizuoka, Japan
   Heavy Ion Centers Opening.                          2014    Zhuhai , China
                                                       2014?   Shanghai, China
                                                       2014?   South Africa
                                                       2014?   Austria        CC
                         Over 8,000 patients treated                  CC
                         with Carbon Ions by 2010!               C
                                                           CC
                         2009 Heidleberg Germany
                         2010 Marburg Germany
                         2010 Gunma , Japan
                                                       C
                                                  C
                                            CC
                                                           Main stream phase
               2002 Hyogo Japan                   Carbon Ions are entering
                                   C              the mainstream clinical
     1997 GSI Germany
                                                  usage phase with
1994: Chiba, Japan       C                        rapid acceleration of
                     C   Proving                  Heavy Ion Centers
                         phase                    opening.
2011    Medipolis, Japan
 5 years from now, Proton Centers                      2012?   Pavia, Italy
 will be fighting the stigma of being                  2012    Kiel, Germany
 “YESTERDAY’S” technology.                             2013    Shizuoka, Japan
                                                       2014    Zhuhai , China
                                                       2014?   Shanghai, China
Planners and decision
makers will be                                         2014?   South Africa
questioned, Why                                        2014?   Austria
                                                                           C  C
didn’t they see this
trend coming??
                         Over 8,000 patients treated                  CC
                         with Carbon Ions by 2010!               C
                                                           CC
                         2009 Heidleberg Germany
                         2010 Marburg Germany
                         2010 Gunma , Japan
                                                       C
                                                  C
                                            CC
               2002 Hyogo Japan
                                                5 years from now, those
     1997 GSI Germany
                                   C            who had the foresight to
                                                go with Carbon Ions
1994: Chiba, Japan       C                      today, will be admired as
                     C   Proving
                                                the strategic thinkers and
                         Stage
                                                planners tomorrow.
• Deliver 20x’s the cancer killing power of
The Bragg Peak Systems
                            Protons.
  Medical Advantage
                          • Cure the Patient 4 to 10x’s faster


                          • Financial earning potential over a Proton Center is
The Bragg Peak Systems      staggering.
  Financial Advantage     • Proton’s will find it hard to compete with Heavy Ion
                            Centers in the future.


                          • Shorter treatment times potentially 4 to 10x’s less.
The Bragg Peak Systems    • Less Stress for the patient Physically, Emotionally and
 Benefit to the Patient     Financially.
                          • Less unnecessary radiation exposure.


                          • A Heavy Ion Center will provide maximum advantage
The Bragg Peak Systems      to the general public by having the capability to treat
   Benefit to Society       many multiples more patients than a Proton center
                            with the same number of treatment rooms.
                                                Lester Lin ver. 1   10/4/2012
The only company offering an
upgradable Proton Therapy System

The only company with a
firm commitment to deliver an
FDA approved system from the onset.

Bringing Heavy Ion systems to market
at an affordable price point.

                   Lester Lin ver. 3   10/4/2012   27
We hope you have caught our vision and inspiration and
choose Bragg Peak Systems as your partner for your FDA
approved Particle Treatment System.




 With all sincerity, the team from




                                     Lester Lin ver. 3   10/4/2012 JP   28
We’re all about saving lives




                  Lester Lin ver. 3   10/4/2012   29

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Ion Therapy: A More Effective Way to Treat Cancer

  • 1. “The International Agency for Research on Cancer projects that by 2030 almost 21.4 million new cases will be diagnosed annually…..” http://www.cbc.ca/health/story/2010/06 /02/cancer-world-statistics.html Lester Lin ver. 1 10/4/2012
  • 2. An simple primer on various treatments for cancer such as Photons, Protons, and Carbon ions. Lester Lin v7 10/4/2012
  • 3. Every year, 10’s of millions of people will hear these words from their doctor. You Have Cancer Lester Lin ver. 1 10/4/2012
  • 4.  Typical cancer treatments:  Chemotherapy  Controlled poisoning of your body  Terrible side effects.  Hair loss  Nausea  Digestive tract Surgery  Invasive  Risk of infection  Damage to critical tissue  Scarring  Side effects such as impotence and incontinence for prostate cancer as an example. Lester Lin ver. 1 10/4/2012
  • 5. Typical cancer treatments:  X-ray Radiation Therapy.  Exposure of healthy tissue to radiation  Negative Side effects Cancer X-Ray Radiation bombarding tumor Tumor Lester Lin ver. 1 10/4/2012
  • 6.  Proton P Therapy Protons are propelled through an accelerator at 50% of the speed of light, then shot into the patient’s body aimed precisely at the tumor. Cancer Tumor Lester Lin ver. 1 10/4/2012
  • 7.  Proton P The Bragg Peak describes the characteristic of protons and ions to have a peak release in energy right before it comes to rest. This Therapy accounts for the amazing power to kill cancer cells, while minimizing bad radiation exposure to healthy tissue. There are only 30 Proton Therapy Centers around the world. Cancer Tumor Lester Lin ver. 1 10/4/2012
  • 8. X-Rays expose the healthy tissue to maximum power, then decreases in energy on the way to the tumor. After the tumor, the energy is still dissipating, and irradiating healthy tissue distally to the tumor. Protons are going through healthy tissue at very low radiation levels and at high speed, then reaches peak power at the tumor, delivering peak killing power. The radiation level then drops off very quickly causing little damage to healthy tissue distally.. Carbon Ions also have the Bragg Peak traits, but delivered at over 20x’s the power of protons. Lester Lin ver. 1 10/4/2012
  • 9. Control Ion Pre-Linear Synchrotron System Source C Accelerator Accelerator How Ions are shot. The Ion Source produces carbon ions and feeds it to the Pre-Linear Accelerator which accelerates the carbon ions and feeds it to Beam Line The Synchrotron Accelerator which speeds the carbon ions to 70% the speed of light and shoots them through the Beam Line to the The Gantry, which aims these high speed carbon ions at the patient’s cancerous Gantry tumor Treatment Couch and Chair while the patient is held very still in the Treatment Couch or chair to ensure maximum possible accuracy. Lester Lin ver. 1 10/4/2012
  • 10. Control Ion Synchrotron System Source C Pre-Linear Accelerator Accelerator Beam Line The ions rapidly peak in energy when arriving at the tumor and deliver Cancer Gantry Tumor the killing power. Lester Lin ver. 1 10/4/2012
  • 11.  Carbon Ion Therapy vs. Proton Therapy Bragg Peak Systems, Inc.: A company that will build FDA approved Heavy Ion Therapy Systems. Protons come from Hydrogen molecules. P Carbon ions Carbon come from Carbon molecules. Many times, these are referred to as “Heavy Ions” because they are 20x’s 12x’s heavier than the protons, and cancer much more killing effective than energy protons against of cancer. Protons Lester Lin ver. 1 10/4/2012
  • 12. P •An angry wild elephant is charging at you. •Do you want the gun on Carbon the left? •or the one on the right to protect you? •The small gun can kill an elephant. • But the big one will do it 20 x’s faster and more the efficiently. cancer killing •Elephant = cancer. energy •Protons = small gun of •Carbon Ions = BIG gun. Protons Lin ver. 1 Lester 10/4/2012
  • 13. Protons typically deliver single breaks of DNA strands, which leaves a chance for cancer cells to repair themselves. P P P P Lester Lin ver. 1 10/4/2012
  • 14. Carbon Ions deliver massive double strand breaks of DNA in the cancer Carbon cells, making it impossible for them to repair themselves. Lester Lin ver. 1 10/4/2012
  • 15. X-Ray Radiation: Good Proton Therapy: Better Carbon Ion Therapy: Best  Carbon Ions have shown the ability to kill tumors with 2 to 40x’s less treatment sessions than with Protons.  Consider what that means to a cancer victim.  Full treatments finished in 10 days instead of 40*  Less stress, and less “downtime” for the patient.  Less unnecessary exposure of healthy cells to radiation.  Financial savings for less travel and lodging during treatments, and less work missed Lester Lin ver. 1 10/4/2012
  • 16. 4 room Proton Center compared to 4 room Carbon Ion Center 1 year time frame each administering 36,000 sessions. 1 year comparison forecast of cured patients finishing treatments between a 4 room Carbon-Ion vs. Proton Center 4000 3500 3000 Protons Carbon Ion 2500 900 patients 3,600 patients completing completing 2000 treatments in treatments in one year. one year. 1500 •Higher Revenue 1000 •More Patients Treated. 500 0 Cured Patients Treatments x10 Proton Carbon-ion 2.5 patients per hour-12hrs. Per day-300 days per year. Avg. 40 total proton treatments vs. 10 total carbon treatments Lester Lin ver. 1 10/4/2012
  • 17. 4 room Proton Center compared to 4 room Carbon Ion Center 25 year time frame 25 year comparison forecast of cured patients finishing treatments between a 4 room Carbon-Ion vs. Proton Center 4000 3500 Over the next 25 years… let’s examine the long term effect: If you go with Protons, 67,500 less people will get treated for their cancer 3000 from your center. 2500 A Heavy Ion center, charging the same price to complete cancer treatments as 2000 a Proton center should generate 400 to 1000% more profit. On 1500 basis, compare generating 45 million USD yearly revenue as a Proton this center, (just for Proton treatments) or 180 million USD as a Heavy Ions Center… or how about DOUBLE THAT??? (which is a possibility) 1000 Over 25 years, 500 1.125 billion vs. 4.5 billion USD 0 Treated Patients Treatments x10 Proton Carbon-ion 2.5 patients per hour-12hrs. Per day-300 days per year. Avg. 40 total proton treatments vs. 10 total carbon treatments Lester Lin ver. 1 10/4/2012
  • 18. The Bragg Peak Systems business plan is to build a 160 million USD product with only 17 million of start- up capital, and no debt. Boeing invested over 2 billion USD to develop the 747 in the 1960’s to produce a product that sold for Bragg Peak will produce the Heavy 22 million USD each. Ion System with FDA approval in 4 years starting from the completion of http://www.centennialofflight.gov/essay/Aerospa ce/Boeing_747/Aero21.htm funding. Lester Lin v7 10/4/2012 18
  • 19. Each year, an enemy on American soil kills over 550,000 Americans, and takes over 1.5 million new hostages. the enemy is CANCER Lester Lin v7 10/4/2012 19
  • 20. The National Missile Defense Program: The projected cost of the program for the years 2004 to 2009 will be $53,000,000,000 USD (53 billion) for protection. We ask for investor participation of just $17 million USD to bring the best proven weapon against cancer into a reality.Lester Lin v7 20 10/4/2012
  • 21. C C C C $50,000 USD Carbon Ion C C Treatment fee C C C C 10 Treatments in 2 Weeks @ $5,000 USD ea. = $50,000 40 Treatments in 8 Weeks @ $1,250 USD ea. = $50,000 P P P P P P P P P P P P P P P P $50,000 USD P P P P P P P P Proton Treatment fee P P P P P P P P P P P P P P P P Lester Lin ver. 1 10/4/2012
  • 22. C Benefits for the Patient •Saved 7 weeks of time C •Saved 7 weeks of lodging expenses $50,000 USD •Saved 7 weeks of lost work-time Carbon Ion C •Reduced the stress of treatment by 7 weeks. Treatment fee C Benefits for the Medical Center •1000% more revenue per treatment. •Up to 10x’s more patients cured in equal time period. 4 C Treatments in 1 Week @ $12,500 USD ea. = $50,000 40 P Treatments in 8 Weeks @ $1,250 USD ea. = $50,000 P P P P P P P P P P P P P P P P $50,000 USD P P P P P P P P Proton Treatment fee P P P P P P P P P P P P P P P P Lester Lin ver. 1 10/4/2012
  • 23. The future of treating a cancer patient at a much lower price point than current fees can be accomplished with Heavy Ion Therapy. This is of prime importance for countries with national health insurance.
  • 24. 2011 Medipolis, Japan 2012? Pavia, Italy 2012 Kiel, Germany History and Plans of 2013 Shizuoka, Japan Heavy Ion Centers Opening. 2014 Zhuhai , China 2014? Shanghai, China 2014? South Africa 2014? Austria CC Over 8,000 patients treated CC with Carbon Ions by 2010! C CC 2009 Heidleberg Germany 2010 Marburg Germany 2010 Gunma , Japan C C CC Main stream phase 2002 Hyogo Japan Carbon Ions are entering C the mainstream clinical 1997 GSI Germany usage phase with 1994: Chiba, Japan C rapid acceleration of C Proving Heavy Ion Centers phase opening.
  • 25. 2011 Medipolis, Japan 5 years from now, Proton Centers 2012? Pavia, Italy will be fighting the stigma of being 2012 Kiel, Germany “YESTERDAY’S” technology. 2013 Shizuoka, Japan 2014 Zhuhai , China 2014? Shanghai, China Planners and decision makers will be 2014? South Africa questioned, Why 2014? Austria C C didn’t they see this trend coming?? Over 8,000 patients treated CC with Carbon Ions by 2010! C CC 2009 Heidleberg Germany 2010 Marburg Germany 2010 Gunma , Japan C C CC 2002 Hyogo Japan 5 years from now, those 1997 GSI Germany C who had the foresight to go with Carbon Ions 1994: Chiba, Japan C today, will be admired as C Proving the strategic thinkers and Stage planners tomorrow.
  • 26. • Deliver 20x’s the cancer killing power of The Bragg Peak Systems Protons. Medical Advantage • Cure the Patient 4 to 10x’s faster • Financial earning potential over a Proton Center is The Bragg Peak Systems staggering. Financial Advantage • Proton’s will find it hard to compete with Heavy Ion Centers in the future. • Shorter treatment times potentially 4 to 10x’s less. The Bragg Peak Systems • Less Stress for the patient Physically, Emotionally and Benefit to the Patient Financially. • Less unnecessary radiation exposure. • A Heavy Ion Center will provide maximum advantage The Bragg Peak Systems to the general public by having the capability to treat Benefit to Society many multiples more patients than a Proton center with the same number of treatment rooms. Lester Lin ver. 1 10/4/2012
  • 27. The only company offering an upgradable Proton Therapy System The only company with a firm commitment to deliver an FDA approved system from the onset. Bringing Heavy Ion systems to market at an affordable price point. Lester Lin ver. 3 10/4/2012 27
  • 28. We hope you have caught our vision and inspiration and choose Bragg Peak Systems as your partner for your FDA approved Particle Treatment System. With all sincerity, the team from Lester Lin ver. 3 10/4/2012 JP 28
  • 29. We’re all about saving lives Lester Lin ver. 3 10/4/2012 29

Hinweis der Redaktion

  1. ed