To determine if a mutation is recessive or dominant, one would analyze how the mutation is expressed in offspring from a cross between a heterozygous carrier and a normal individual. Northern blots are preferred for detecting specific RNA sequences, while microarrays allow for analyzing expression of many genes simultaneously but with less specificity. Mobile elements are segments of DNA that can move within and between genomes, often through an RNA intermediate copied back into DNA at a new location. One way to identify a human genetic disease is through linkage analysis, which maps DNA markers near a disease gene within families.
should be at least two paragraphs long, or more, depending upon the .pdf
1. should be at least two paragraphs long, or more, depending upon the depth of the response.
Describe the techniques used to determine whether a mutation is recessive or dominant.
Compare the information obtained by Northern Blots and Microarrays: when is one technique
preferred over the other?
What are mobile elements and how are they moved?
Discuss one way to identify a human genetic disease.
