This document provides an overview of topics related to mitochondria that will be covered, including:
- Mitochondrial structure and function
- Aerobic metabolism in mitochondria
- The role of anaerobic and aerobic metabolism in exercise
- Oxidative phosphorylation and ATP formation
- Electron transport chain complexes
- Establishing a proton motive force
- ATP synthase structure
- The mechanism of ATP formation using the proton gradient
- Peroxisomes and human diseases resulting from abnormal mitochondrial or peroxisomal function
2. TEMAS A ABORDAR
BIOLOGÍA CELULAR, KARP 8VA EDICION.
• Estructura mitocondrial y función
• Metabolismo aeróbico en la mitocondria
• PERSPECTIVA HUMANA: Función del metabolismo anaeróbico y aeróbico en el
ejercicio
• La fosforilación oxidativa en la formación de la ATP
• Complejos del transporte de electrones
• Establecimiento de una fuerza protón motriz
• La estructura de la ATP sintasa
• El mecanismo de cambio de la fijación en la formación de ATP
• Usando el gradiente de protones
• Peroxisomas
• PERSPECTIVA HUMANA: Enfermedades que resultan de una función
mitocondrial o peroxisomal anormal
4. Introducción
• El primero en describir las mitocondrias fue R. Altman Altman en 1890 las
identificó como unas estructuras intracelulares a las que llamó mioblastos.
• Cuatro años después, Benda denominó a esas estructuras mitocondrias (del
griego mitos, hilo y condros, gránulo).
• En 1900, L. Michaelis encontró que el verde de Jano B teñía a las
mitocondrias y,
• durante varios años, esta tinción se utilizó en su identificación.
• Albert Claude, en la década de 1940 estableció las bases para la obtención de
organelos intracelulares, morfológica y bioquímicamente intactos.
7. Mercury is the closest planet to the Sun
and the smallest one in the entire Solar
System. This planet's name has
nothing to do with the liquid metal,
since Mercury was named after the
Roman messenger god
Despite being closer to the Sun than
Venus, Mercury’s temperatures aren't
as terribly hot as that planet's. Its
surface is quite similar to that of Earth's
Moon, which means there are a lot of
craters and many plains, too
Cell biology basics
Function
Structure
9. Saturn is a gas giant and has
several rings. It's composed of
hydrogen
Neptune is the fourth-largest object
by diameter in the Solar System
Types of cells
Prokaryotes
Eukaryotes
10. Neptune is the farthest
planet from the Sun
The Sun is the star at the
center of all
The Moon is Earth’s only
natural satellite
About biology
Branch Science Organisms
11. Cell structure
Venus has a beautiful name and
is the second planet from the Sun
Earth is the only planet that
harbors life in the Solar System
Despite being red, Mars is
actually a cold place
Jupiter is a gas giant and the
biggest planet in the Solar
System
Membrane
Cytoplasm
Wall
Nucleus
12. Mercury is the smallest
planet of them all
Venus has a beautiful
name and is very hot
Despite being red, Mars is
actually a cold place
Jupiter is the biggest
planet in the Solar System
Earth is the only planet
known to harbor life
Functions of the cell
Support Mitosis Transport
Energy Reproduction
13. Mercury is the smallest
planet of them all
Venus has a beautiful
name and very hot
Despite being red, Mars is
actually a cold place
Jupiter is the biggest
planet in the Solar System
Earth is the only planet
known to harbor life
Saturn is not the only
planet with rings
Cell organelles
Nucleolus Chromosome Golgi
Ribosome
Vacuoles lysosome
18. Images reveal large amounts of data,
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A picture
reinforces the
concept
20. Venus is the second planet from the Sun
1665
Mars was named after a god
21. Jupiter is a gas giant and
the biggest planet in the
System
Saturn is the second-largest
planet in the Solar System
16%
44%
Some useful statistics
Small cells
Medium cells
Neptune is the farthest
planet from the Sun
40% Large cells
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26. Findings
Location C
Pluto is now seen as
a dwarf planet
Location A
The Sun is the star at
the center of all
Location B
The Moon is Earth’s
only natural satellite
27. Cell discovery timeline
1674
Saturn was named
after a Roman god
1595
Despite being red,
Mars is very cold
1655
Jupiter is the
biggest planet
1833
Neptune is very far
away from the Sun
28. Parts of the cell
Membrane
Venus has a beautiful name
and is the second planet
from the Sun
Nucleus
Despite being red, Mars is
actually a cold place. It's full
of iron oxide dust
Golgi
Mercury is the closest planet
to the Sun and the smallest
one of them all
Mitochondria
Earth is the third planet from
the Sun and the only one
that harbors life
29. Physiology chart
Phase Description
Prophase Initiation of the assembly of the mitotic spindle
Metaphase The microtubules start pulling the chromosomes with equal force
Anaphase The chromosomes are then pulled towards the pole by the fibres
Telophase The chromosomes that cluster at the two poles start coalescing
Cytokinesis Denotes the division of the cytoplasm to form two daughter cells
30. Organelles’ frequency
Mitochondria
Earth is the only planet that
harbors life
Lysosomes
Mercury is the closest
planet to the Sun
ER
Venus has a beautiful name
but is a hot place
Follow the link in the graph to modify its data and then paste
the new one here. For more info, click here
Cell A
Cell C
Cell B
0 100
75
50
25
31. Recent studies
University A
Mercury is the closest
planet to the Sun
University B
Venus has a beautiful
name but is hot
Follow the link in the graph to modify its data and then paste the new one here. For more info, click here
Topic A
100
Topic E
Topic B Topic C Topic D
0
25
50
75
33. Reviewing the nucleus
Nuclear pores
Mercury is the closest planet to the Sun
and the smallest one of them all
Nuclear membrane
Earth is the third planet from the Sun
and the only one that harbors life
Chromatin
Venus has a beautiful name and is the
second planet from the Sun
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“Despite being red,
Mars is actually a
very cold place”
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smallest planet in
the Solar System”
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farthest planet from
the Sun”
“Saturn is a gas
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