1. Mining and communicating biomedical knowledge Lars Juhl Jensen

2. Part 1 complex regulation

3. cell-cycle regulation

5. microarrays

7. time courses

8. Gauthier et al., Nucleic Acids Research , 2007

9. protein interactions

10. Jensen & Bork, Science , 2008

11. temporal network

12. de Lichtenberg, Jensen et al., Science , 2005

13. just-in-time assembly

14. de Lichtenberg, Jensen et al., Cell Cycle , 2007

15. evolutionary flexibility

16. individual genes

17. Jensen, Jensen, de Lichtenberg et al., Nature , 2006

18. protein complexes

19. Jensen, Jensen, de Lichtenberg et al., Nature , 2006

20. just-in-time assembly

21. Part 2 buried knowledge

22. exponential growth

25. some things are constant

27. ~45 seconds per paper

28. computer

29. as smart as a dog

30. teach it specific tricks

33. named entity recognition

34. new uses for old drugs

35. Campillos & Kuhn et al., Science , 2008

36. augmented browsing

37. Pafilis, O’Donoghue, Jensen et al., Nature Biotechnology , 2009

38. semantic indexing

39. >10 km <10 hours

41. Part 3 science communication

42. ~150 years ago

44. today

46. incremental evolution

47. historical baggage

51. subscription charges

52. space restrictions

53. issues

54. editorial filtering

55. pre-publication peer review

56. the world has changed

58. internet economy

60. publishing is changing

61. open access

62. free to download

63. free to reuse

64. same publication process

66. publish first

68. filter later

70. post-publication peer review

71. conference reporting

72. Brumfiel, Nature , 2009

73. Saunders et al., PLoS Computational Biology , 2009