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A NEURAL MECHANISM
FOR THE EMERGENCE OF
NON-CRITICAL POWER LAWS
Serena Di Santo
21/06/2016
Lake Como School
tissue on array local field potentials thresholded signals
A NEURAL MECHANISM
FOR THE EMERGENCE OF
NON-CRITICAL POWER LAWS
c r i t i c a l
WILSON-COWAN MODEL
AND BALANCED AMPLIFICATION OF FLUCTUATIONS
E
I
wI
wI
wE
wE
@tE = ↵E + (1 E)f(s)
@tI = ↵I + (1 I)f(s)
f(s) = ✓[tanh(s)]
s = wEE wII + h
'
Benayoun M, Cowan JD, van Drongelen W, Wallace E, (2010) PLoS Comput Biol
Murphy BK, Miller K, (2009) Neuron
wE wI
E
I
not balanced
+
p
↵E + (1 E)f(s)⌘E
+
p
↵I + (1 I)f(s)⌘I
NON NORMAL FORMS AND A NOISE INDUCED ZERO MODE
Linear
stability close to
the fixed point…
Non Diagonalizable
Non orthogonal Eigenvect
Define Pseudospectra
˙⇢ = a⇢ b⇢2
+ h +
p
⇢⌘(t)
T U N N
E
L
I N
G
Amplificated fluctuations
+noise
☞
NON
NORMAL
FORM
AT
A 6= AAT
Pst(⇢) ⇠
1
⇢1 2h
2
SIMILAR PHENOMENON, DIFFERENT REGULATORY MECHANISM:
TSODYKS-MARKRAM MODEL FOR SYNAPTIC PLASTICITY
˙R =
1
⌧
(Rm
R) u⇢R⇢ b⇢2 c⇢3 + !⇢R +
p
⇢⌘˙⇢ = a⇢ b⇢2 c⇢3 + h + !⇢R +
p
⇢⌘
NON-NORMAL FORMS ☞AMPLIFICATION OF FLUCTUATIONS ☞
NOISE INDUCED ZERO MODE☞ ☞NON-CRITICAL POWER LAWS
THANKS TO
MIGUEL ANGEL Muñoz & PABLO Villegas

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A NEURAL MECHANISM FOR THE EMERGENCE OF NON-CRITICAL POWER LAWS - Serena Di Santo

  • 1. A NEURAL MECHANISM FOR THE EMERGENCE OF NON-CRITICAL POWER LAWS Serena Di Santo 21/06/2016 Lake Como School
  • 2. tissue on array local field potentials thresholded signals A NEURAL MECHANISM FOR THE EMERGENCE OF NON-CRITICAL POWER LAWS c r i t i c a l
  • 3. WILSON-COWAN MODEL AND BALANCED AMPLIFICATION OF FLUCTUATIONS E I wI wI wE wE @tE = ↵E + (1 E)f(s) @tI = ↵I + (1 I)f(s) f(s) = ✓[tanh(s)] s = wEE wII + h ' Benayoun M, Cowan JD, van Drongelen W, Wallace E, (2010) PLoS Comput Biol Murphy BK, Miller K, (2009) Neuron wE wI E I not balanced + p ↵E + (1 E)f(s)⌘E + p ↵I + (1 I)f(s)⌘I
  • 4. NON NORMAL FORMS AND A NOISE INDUCED ZERO MODE Linear stability close to the fixed point… Non Diagonalizable Non orthogonal Eigenvect Define Pseudospectra ˙⇢ = a⇢ b⇢2 + h + p ⇢⌘(t) T U N N E L I N G Amplificated fluctuations +noise ☞ NON NORMAL FORM AT A 6= AAT Pst(⇢) ⇠ 1 ⇢1 2h 2
  • 5. SIMILAR PHENOMENON, DIFFERENT REGULATORY MECHANISM: TSODYKS-MARKRAM MODEL FOR SYNAPTIC PLASTICITY ˙R = 1 ⌧ (Rm R) u⇢R⇢ b⇢2 c⇢3 + !⇢R + p ⇢⌘˙⇢ = a⇢ b⇢2 c⇢3 + h + !⇢R + p ⇢⌘ NON-NORMAL FORMS ☞AMPLIFICATION OF FLUCTUATIONS ☞ NOISE INDUCED ZERO MODE☞ ☞NON-CRITICAL POWER LAWS
  • 6. THANKS TO MIGUEL ANGEL Muñoz & PABLO Villegas