SlideShare ist ein Scribd-Unternehmen logo
1 von 50
Preventive And Social
Obstetrics
Dr. Ghanshyam Patel
M.D Gynec
Latestupdateswithreferenceto:
1. Investigations
2. Clinical examination
3. Non therapeutic mx.
4. Developmental anomaly
Social obstetrics
• It is a branch of preventive medicine
• Relation between social and environmental
factors and human reproduction, even in
preconception and premarital period
 Social factors
 Age at marriage
 Age at child bearing
 Birth spacing
 Family size
 Fertility pattern
 Level of education
 Economic status
 Role of woman in society
Investigations
• UPT
• β-Hcg
• CBC
• BG
• HIV
• Serum creatinine ,
• PT , APTT
• LFT
• HBSAG
• VDRL
• RBS
• URINE-routine and micro
• TSH
• OPTIONAL-Vit. D ,Vit. B12
 Clinical examination
history
symptoms
signs
 TVS
 TAS
 3D USG AND COLOR DOPPLER
 STUDY
 MRI
NON THERAPEUTIC MX.
1. Adolescent health screening
2. Premarital counselling
3. Preconception counselling
4. Good ANC
5. Birth spacing
Social factor
1. Age at marriage
2. Age at pregnancy
3. Women empowerment
4. Women education
5. Population Control
Anomalies
Past history
Exposure to drug , X’ ray etc.
How to look for it
Chorion villus biopsy,
Amniocentesis
Triple test
Quadruple test
Targeted sonography
3D USG
Cordocentesis
The recent development of high-resolution ultrasound equipment has
markedly improved the diagnostic accuracy of ultrasound. In particular
, the introduction of high-frequency vaginal probes has enabled early
diagnosis of certain fetal abnormalities from the 12th to 14th week of
pregnancy. Such early testing is of special importance for women with
a history of pregnancies associated with birth defects
• 4D USG detects all structural anomalies while color Doppler detects
• outrightly vascular problems, and both can be done in one sitting
• . For down syndrome nuchal translucence, long bone length, major
• structural defect are to be looked for.
• anencephaly
• open spina bifida
• cleft lip
• diaphragmatic hernia
• gastrochisis
• exomphalos
• serious cardiac abnormalities
• bilateral renal agenesis
• lethal skeletal dysplasia
• Edwards' syndrome, or T18
• Patau's syndrome, or T13
Frequent or Occasional Features
Syndromes
Meckel-Gruber Encephalocele, cleft palate, polycystic kidney,
polydactyly, IUGR (A/R)
Dubowitz IUGR, hypertelorism, olinodactyly of fifth finger
(A/R)
Robert IUGR, cleft lip, hypertelorism, hypomelia, CHD,
polycystic kidneys, polyhydramnios, hydrocephalus
(A/R)
Seckel IUGR, facial hypoplasia with prominent nose (A/R)
De Lange IUGR, micrognathia, micromelia, CHD, sporadic
etiology
Coffin-Siris IUGR, CHD, Dandy-Walker anomaly, hypoplastic fifth
finger (unknown etiology)
Bloom IUGR A/R
Chromosomal Deviations
Trisomy 13 Holoprosencephaly, hydronephrosis, polycystic kidneys,
IUGR, single umbilical artery, CHD
Trisomy 18 Polyhydramnios, hydronephrosis, polycystic kidneys, IUGR,
single umbilical artery, CHD, omphalocele, choroid plexus
cysts
VATER associations Esophageal atresia, radial hypoplasia, renal dysplasia
Del (4p) and Del (5p) Hypertelorism, IUGR, CHD
Del (13 q) Hypertelorism, IUGR,CHD, hydrocephalus, small thumbs
Del (18p) IUGR, holoprosencephaly
Del (18q) Cleft lip, CHD, horseshoe kidney
Environmental Factors
Alcohol IUGR, hydrocephalus, CHD
Amniopterin IUGR, hydrocephalus, neural tube defect,
hypoplasia/frontal bone, cleft palate, broad nasal bridge,
hypertelorism, CHD
Hydantoin IUGR, hypertelorism, cleft lip, CHD, duodenal atresia,
single umbilical artery
Maternal phenylketonuria IUGR, CHD
Rubella IUGR, CHD
Abnormal Ultrasound
Feature
Skeletal
Dysplasias
Amniotic fluid volume and polyhydramnios Robert S,
VATERS
association
Acromelia Ellis-van
Creveld
dysplasia,
Poland
sequence
Gestation (weeks) <10 10–12 12–14 >14
Patients 19 34 65 26
Four chamber - 13 (37) 44 (68) 21 (81)
Head - 13 (37) 43 (66) 16 (62)
Spine - 5 (15) 28 (43) 8 (31)
Stomach 2 (10) 19 (56) 62 (95) 24 (92)
Kidneys - 5 (15) 38 (58) 14 (54)
Bladder 3 (6) 14 (42) 52 (80) 23 (88)
Take Home message
• Adolesence health care
• Premarital counselling
• Marriage at approptiate age
• Child bearing at appropriate age
• Good anc
• Good intrapatum care
• Good pnc
• Woman empowerment
• Anomaly scan at 18to22k
• Nowdays 3d or 4d usg at 10wk to14
• Cvs
• Amniocentesis
• Cordocentesis
• If require opion of fetal medicine expert
THANK YOU

Weitere ähnliche Inhalte

Was ist angesagt?

Pelvic inflammatory diseases
Pelvic inflammatory diseasesPelvic inflammatory diseases
Pelvic inflammatory diseases
Muni Venkatesh
 

Was ist angesagt? (20)

Vaginal Hysterectomy
Vaginal HysterectomyVaginal Hysterectomy
Vaginal Hysterectomy
 
Amenorrhea
AmenorrheaAmenorrhea
Amenorrhea
 
Case Study on Intrauterine Growth Restriction
Case Study on Intrauterine Growth RestrictionCase Study on Intrauterine Growth Restriction
Case Study on Intrauterine Growth Restriction
 
Ultrasonography in pregnancy
Ultrasonography in pregnancyUltrasonography in pregnancy
Ultrasonography in pregnancy
 
Breast Examination
Breast ExaminationBreast Examination
Breast Examination
 
Rh negative pregnancy
Rh negative pregnancyRh negative pregnancy
Rh negative pregnancy
 
White discharge leucorrhoea
White discharge  leucorrhoeaWhite discharge  leucorrhoea
White discharge leucorrhoea
 
Dilatation and curettage
Dilatation and curettageDilatation and curettage
Dilatation and curettage
 
Infertility- A CASE DISCUSSION
Infertility- A CASE DISCUSSION Infertility- A CASE DISCUSSION
Infertility- A CASE DISCUSSION
 
Benign ovarian tumours
Benign ovarian tumoursBenign ovarian tumours
Benign ovarian tumours
 
The gynaecological examination ppt
The gynaecological examination pptThe gynaecological examination ppt
The gynaecological examination ppt
 
antenatal fetal surveillance
antenatal fetal surveillanceantenatal fetal surveillance
antenatal fetal surveillance
 
Endometrial hyperplasia
Endometrial hyperplasiaEndometrial hyperplasia
Endometrial hyperplasia
 
Medicolegal aspects in obstetrics
Medicolegal aspects in obstetricsMedicolegal aspects in obstetrics
Medicolegal aspects in obstetrics
 
GYNECOLOGICAL CASE TAKING -1
GYNECOLOGICAL CASE TAKING -1GYNECOLOGICAL CASE TAKING -1
GYNECOLOGICAL CASE TAKING -1
 
Stillbirth
StillbirthStillbirth
Stillbirth
 
Rh iso immunization
Rh  iso immunization Rh  iso immunization
Rh iso immunization
 
Breast Cysts Galactocele.pptx
Breast Cysts Galactocele.pptxBreast Cysts Galactocele.pptx
Breast Cysts Galactocele.pptx
 
Adenomyosis
AdenomyosisAdenomyosis
Adenomyosis
 
Pelvic inflammatory diseases
Pelvic inflammatory diseasesPelvic inflammatory diseases
Pelvic inflammatory diseases
 

Ähnlich wie Preventive and social obstetrics

down syndrome Presentation. providing basic knowledge about down syndrome an...
down syndrome Presentation. providing basic knowledge about  down syndrome an...down syndrome Presentation. providing basic knowledge about  down syndrome an...
down syndrome Presentation. providing basic knowledge about down syndrome an...
romelsolanki1616
 

Ähnlich wie Preventive and social obstetrics (20)

Causes & prevention of disabilities
Causes & prevention of disabilitiesCauses & prevention of disabilities
Causes & prevention of disabilities
 
5 la genetica clínica en pediatria
5 la genetica clínica en pediatria5 la genetica clínica en pediatria
5 la genetica clínica en pediatria
 
IOSR Journal of Pharmacy (IOSRPHR)
IOSR Journal of Pharmacy (IOSRPHR)IOSR Journal of Pharmacy (IOSRPHR)
IOSR Journal of Pharmacy (IOSRPHR)
 
Downs
DownsDowns
Downs
 
Down syndrome
Down syndromeDown syndrome
Down syndrome
 
congenital anomalies.pptx
congenital anomalies.pptxcongenital anomalies.pptx
congenital anomalies.pptx
 
Care of Pediatric Down Syndrome
Care of Pediatric Down SyndromeCare of Pediatric Down Syndrome
Care of Pediatric Down Syndrome
 
Global developmental delay & Intellectual disability
Global developmental delay & Intellectual disabilityGlobal developmental delay & Intellectual disability
Global developmental delay & Intellectual disability
 
Disorders of growth
Disorders of growthDisorders of growth
Disorders of growth
 
Vascular tumors
Vascular tumorsVascular tumors
Vascular tumors
 
Medical-Genetics-lecture-1.pptx
Medical-Genetics-lecture-1.pptxMedical-Genetics-lecture-1.pptx
Medical-Genetics-lecture-1.pptx
 
down syndrome Presentation. providing basic knowledge about down syndrome an...
down syndrome Presentation. providing basic knowledge about  down syndrome an...down syndrome Presentation. providing basic knowledge about  down syndrome an...
down syndrome Presentation. providing basic knowledge about down syndrome an...
 
Genetics in Infertility 2023.pptx
Genetics in Infertility 2023.pptxGenetics in Infertility 2023.pptx
Genetics in Infertility 2023.pptx
 
detailed Case History taking of a patient
detailed Case History taking of a patientdetailed Case History taking of a patient
detailed Case History taking of a patient
 
Genetic counselling - a review
Genetic counselling - a reviewGenetic counselling - a review
Genetic counselling - a review
 
Genetic counseling
Genetic counselingGenetic counseling
Genetic counseling
 
Endocrine Approach In Pws
Endocrine Approach In PwsEndocrine Approach In Pws
Endocrine Approach In Pws
 
Growth Disorders
Growth DisordersGrowth Disorders
Growth Disorders
 
Growth Disorders.pptx
Growth Disorders.pptxGrowth Disorders.pptx
Growth Disorders.pptx
 
Growth Disorders.pptx
Growth Disorders.pptxGrowth Disorders.pptx
Growth Disorders.pptx
 

Kürzlich hochgeladen

Top profile Call Girls In fatehgarh [ 7014168258 ] Call Me For Genuine Models...
Top profile Call Girls In fatehgarh [ 7014168258 ] Call Me For Genuine Models...Top profile Call Girls In fatehgarh [ 7014168258 ] Call Me For Genuine Models...
Top profile Call Girls In fatehgarh [ 7014168258 ] Call Me For Genuine Models...
gajnagarg
 
Abortion pill for sale in Muscat (+918761049707)) Get Cytotec Cash on deliver...
Abortion pill for sale in Muscat (+918761049707)) Get Cytotec Cash on deliver...Abortion pill for sale in Muscat (+918761049707)) Get Cytotec Cash on deliver...
Abortion pill for sale in Muscat (+918761049707)) Get Cytotec Cash on deliver...
instagramfab782445
 
怎样办理巴斯大学毕业证(Bath毕业证书)成绩单留信认证
怎样办理巴斯大学毕业证(Bath毕业证书)成绩单留信认证怎样办理巴斯大学毕业证(Bath毕业证书)成绩单留信认证
怎样办理巴斯大学毕业证(Bath毕业证书)成绩单留信认证
eeanqy
 
怎样办理莫纳什大学毕业证(Monash毕业证书)成绩单留信认证
怎样办理莫纳什大学毕业证(Monash毕业证书)成绩单留信认证怎样办理莫纳什大学毕业证(Monash毕业证书)成绩单留信认证
怎样办理莫纳什大学毕业证(Monash毕业证书)成绩单留信认证
ehyxf
 
怎样办理伦敦国王学院毕业证(KCL毕业证书)成绩单留信认证
怎样办理伦敦国王学院毕业证(KCL毕业证书)成绩单留信认证怎样办理伦敦国王学院毕业证(KCL毕业证书)成绩单留信认证
怎样办理伦敦国王学院毕业证(KCL毕业证书)成绩单留信认证
eeanqy
 
一比一原版(WLU毕业证)罗瑞尔大学毕业证成绩单留信学历认证原版一模一样
一比一原版(WLU毕业证)罗瑞尔大学毕业证成绩单留信学历认证原版一模一样一比一原版(WLU毕业证)罗瑞尔大学毕业证成绩单留信学历认证原版一模一样
一比一原版(WLU毕业证)罗瑞尔大学毕业证成绩单留信学历认证原版一模一样
awasv46j
 
Abortion Pills in Oman (+918133066128) Cytotec clinic buy Oman Muscat
Abortion Pills in Oman (+918133066128) Cytotec clinic buy Oman MuscatAbortion Pills in Oman (+918133066128) Cytotec clinic buy Oman Muscat
Abortion Pills in Oman (+918133066128) Cytotec clinic buy Oman Muscat
Abortion pills in Kuwait Cytotec pills in Kuwait
 
Call Girls In Ratnagiri Escorts ☎️8617370543 🔝 💃 Enjoy 24/7 Escort Service En...
Call Girls In Ratnagiri Escorts ☎️8617370543 🔝 💃 Enjoy 24/7 Escort Service En...Call Girls In Ratnagiri Escorts ☎️8617370543 🔝 💃 Enjoy 24/7 Escort Service En...
Call Girls In Ratnagiri Escorts ☎️8617370543 🔝 💃 Enjoy 24/7 Escort Service En...
Nitya salvi
 
一比一定(购)西悉尼大学毕业证(WSU毕业证)成绩单学位证
一比一定(购)西悉尼大学毕业证(WSU毕业证)成绩单学位证一比一定(购)西悉尼大学毕业证(WSU毕业证)成绩单学位证
一比一定(购)西悉尼大学毕业证(WSU毕业证)成绩单学位证
eqaqen
 
Design-System - FinTech - Isadora Agency
Design-System - FinTech - Isadora AgencyDesign-System - FinTech - Isadora Agency
Design-System - FinTech - Isadora Agency
Isadora Agency
 
Madhyamgram \ (Genuine) Escort Service Kolkata | Service-oriented sexy call g...
Madhyamgram \ (Genuine) Escort Service Kolkata | Service-oriented sexy call g...Madhyamgram \ (Genuine) Escort Service Kolkata | Service-oriented sexy call g...
Madhyamgram \ (Genuine) Escort Service Kolkata | Service-oriented sexy call g...
HyderabadDolls
 

Kürzlich hochgeladen (20)

Top profile Call Girls In fatehgarh [ 7014168258 ] Call Me For Genuine Models...
Top profile Call Girls In fatehgarh [ 7014168258 ] Call Me For Genuine Models...Top profile Call Girls In fatehgarh [ 7014168258 ] Call Me For Genuine Models...
Top profile Call Girls In fatehgarh [ 7014168258 ] Call Me For Genuine Models...
 
Q4-W4-SCIENCE-5 power point presentation
Q4-W4-SCIENCE-5 power point presentationQ4-W4-SCIENCE-5 power point presentation
Q4-W4-SCIENCE-5 power point presentation
 
Just Call Vip call girls Fatehpur Escorts ☎️8617370543 Two shot with one girl...
Just Call Vip call girls Fatehpur Escorts ☎️8617370543 Two shot with one girl...Just Call Vip call girls Fatehpur Escorts ☎️8617370543 Two shot with one girl...
Just Call Vip call girls Fatehpur Escorts ☎️8617370543 Two shot with one girl...
 
Furniture & Joinery Details_Designs.pptx
Furniture & Joinery Details_Designs.pptxFurniture & Joinery Details_Designs.pptx
Furniture & Joinery Details_Designs.pptx
 
Abortion pill for sale in Muscat (+918761049707)) Get Cytotec Cash on deliver...
Abortion pill for sale in Muscat (+918761049707)) Get Cytotec Cash on deliver...Abortion pill for sale in Muscat (+918761049707)) Get Cytotec Cash on deliver...
Abortion pill for sale in Muscat (+918761049707)) Get Cytotec Cash on deliver...
 
The hottest UI and UX Design Trends 2024
The hottest UI and UX Design Trends 2024The hottest UI and UX Design Trends 2024
The hottest UI and UX Design Trends 2024
 
怎样办理巴斯大学毕业证(Bath毕业证书)成绩单留信认证
怎样办理巴斯大学毕业证(Bath毕业证书)成绩单留信认证怎样办理巴斯大学毕业证(Bath毕业证书)成绩单留信认证
怎样办理巴斯大学毕业证(Bath毕业证书)成绩单留信认证
 
怎样办理莫纳什大学毕业证(Monash毕业证书)成绩单留信认证
怎样办理莫纳什大学毕业证(Monash毕业证书)成绩单留信认证怎样办理莫纳什大学毕业证(Monash毕业证书)成绩单留信认证
怎样办理莫纳什大学毕业证(Monash毕业证书)成绩单留信认证
 
怎样办理伦敦国王学院毕业证(KCL毕业证书)成绩单留信认证
怎样办理伦敦国王学院毕业证(KCL毕业证书)成绩单留信认证怎样办理伦敦国王学院毕业证(KCL毕业证书)成绩单留信认证
怎样办理伦敦国王学院毕业证(KCL毕业证书)成绩单留信认证
 
一比一原版(WLU毕业证)罗瑞尔大学毕业证成绩单留信学历认证原版一模一样
一比一原版(WLU毕业证)罗瑞尔大学毕业证成绩单留信学历认证原版一模一样一比一原版(WLU毕业证)罗瑞尔大学毕业证成绩单留信学历认证原版一模一样
一比一原版(WLU毕业证)罗瑞尔大学毕业证成绩单留信学历认证原版一模一样
 
TRose UXPA Experience Design Concord .pptx
TRose UXPA Experience Design Concord .pptxTRose UXPA Experience Design Concord .pptx
TRose UXPA Experience Design Concord .pptx
 
Abortion Pills in Oman (+918133066128) Cytotec clinic buy Oman Muscat
Abortion Pills in Oman (+918133066128) Cytotec clinic buy Oman MuscatAbortion Pills in Oman (+918133066128) Cytotec clinic buy Oman Muscat
Abortion Pills in Oman (+918133066128) Cytotec clinic buy Oman Muscat
 
Raebareli Girl Whatsapp Number 📞 8617370543 | Girls Number for Friendship
Raebareli Girl Whatsapp Number 📞 8617370543 | Girls Number for FriendshipRaebareli Girl Whatsapp Number 📞 8617370543 | Girls Number for Friendship
Raebareli Girl Whatsapp Number 📞 8617370543 | Girls Number for Friendship
 
High Profile Escorts Nerul WhatsApp +91-9930687706, Best Service
High Profile Escorts Nerul WhatsApp +91-9930687706, Best ServiceHigh Profile Escorts Nerul WhatsApp +91-9930687706, Best Service
High Profile Escorts Nerul WhatsApp +91-9930687706, Best Service
 
Mohanlalganj ! Call Girls in Lucknow - 450+ Call Girl Cash Payment 9548273370...
Mohanlalganj ! Call Girls in Lucknow - 450+ Call Girl Cash Payment 9548273370...Mohanlalganj ! Call Girls in Lucknow - 450+ Call Girl Cash Payment 9548273370...
Mohanlalganj ! Call Girls in Lucknow - 450+ Call Girl Cash Payment 9548273370...
 
Call Girls In Ratnagiri Escorts ☎️8617370543 🔝 💃 Enjoy 24/7 Escort Service En...
Call Girls In Ratnagiri Escorts ☎️8617370543 🔝 💃 Enjoy 24/7 Escort Service En...Call Girls In Ratnagiri Escorts ☎️8617370543 🔝 💃 Enjoy 24/7 Escort Service En...
Call Girls In Ratnagiri Escorts ☎️8617370543 🔝 💃 Enjoy 24/7 Escort Service En...
 
Essential UI/UX Design Principles: A Comprehensive Guide
Essential UI/UX Design Principles: A Comprehensive GuideEssential UI/UX Design Principles: A Comprehensive Guide
Essential UI/UX Design Principles: A Comprehensive Guide
 
一比一定(购)西悉尼大学毕业证(WSU毕业证)成绩单学位证
一比一定(购)西悉尼大学毕业证(WSU毕业证)成绩单学位证一比一定(购)西悉尼大学毕业证(WSU毕业证)成绩单学位证
一比一定(购)西悉尼大学毕业证(WSU毕业证)成绩单学位证
 
Design-System - FinTech - Isadora Agency
Design-System - FinTech - Isadora AgencyDesign-System - FinTech - Isadora Agency
Design-System - FinTech - Isadora Agency
 
Madhyamgram \ (Genuine) Escort Service Kolkata | Service-oriented sexy call g...
Madhyamgram \ (Genuine) Escort Service Kolkata | Service-oriented sexy call g...Madhyamgram \ (Genuine) Escort Service Kolkata | Service-oriented sexy call g...
Madhyamgram \ (Genuine) Escort Service Kolkata | Service-oriented sexy call g...
 

Preventive and social obstetrics

  • 1. Preventive And Social Obstetrics Dr. Ghanshyam Patel M.D Gynec
  • 2. Latestupdateswithreferenceto: 1. Investigations 2. Clinical examination 3. Non therapeutic mx. 4. Developmental anomaly
  • 3. Social obstetrics • It is a branch of preventive medicine • Relation between social and environmental factors and human reproduction, even in preconception and premarital period
  • 4.  Social factors  Age at marriage  Age at child bearing  Birth spacing  Family size  Fertility pattern  Level of education  Economic status  Role of woman in society
  • 5. Investigations • UPT • β-Hcg • CBC • BG • HIV • Serum creatinine , • PT , APTT • LFT • HBSAG • VDRL • RBS • URINE-routine and micro • TSH • OPTIONAL-Vit. D ,Vit. B12
  • 7.  TVS  TAS  3D USG AND COLOR DOPPLER  STUDY  MRI
  • 8. NON THERAPEUTIC MX. 1. Adolescent health screening 2. Premarital counselling 3. Preconception counselling 4. Good ANC 5. Birth spacing
  • 9. Social factor 1. Age at marriage 2. Age at pregnancy 3. Women empowerment 4. Women education 5. Population Control
  • 10. Anomalies Past history Exposure to drug , X’ ray etc. How to look for it Chorion villus biopsy, Amniocentesis Triple test Quadruple test Targeted sonography 3D USG Cordocentesis
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19. The recent development of high-resolution ultrasound equipment has markedly improved the diagnostic accuracy of ultrasound. In particular , the introduction of high-frequency vaginal probes has enabled early diagnosis of certain fetal abnormalities from the 12th to 14th week of pregnancy. Such early testing is of special importance for women with a history of pregnancies associated with birth defects
  • 20. • 4D USG detects all structural anomalies while color Doppler detects • outrightly vascular problems, and both can be done in one sitting • . For down syndrome nuchal translucence, long bone length, major • structural defect are to be looked for.
  • 21. • anencephaly • open spina bifida • cleft lip • diaphragmatic hernia • gastrochisis • exomphalos • serious cardiac abnormalities • bilateral renal agenesis • lethal skeletal dysplasia • Edwards' syndrome, or T18 • Patau's syndrome, or T13
  • 22. Frequent or Occasional Features Syndromes Meckel-Gruber Encephalocele, cleft palate, polycystic kidney, polydactyly, IUGR (A/R) Dubowitz IUGR, hypertelorism, olinodactyly of fifth finger (A/R) Robert IUGR, cleft lip, hypertelorism, hypomelia, CHD, polycystic kidneys, polyhydramnios, hydrocephalus (A/R) Seckel IUGR, facial hypoplasia with prominent nose (A/R) De Lange IUGR, micrognathia, micromelia, CHD, sporadic etiology Coffin-Siris IUGR, CHD, Dandy-Walker anomaly, hypoplastic fifth finger (unknown etiology) Bloom IUGR A/R
  • 23. Chromosomal Deviations Trisomy 13 Holoprosencephaly, hydronephrosis, polycystic kidneys, IUGR, single umbilical artery, CHD Trisomy 18 Polyhydramnios, hydronephrosis, polycystic kidneys, IUGR, single umbilical artery, CHD, omphalocele, choroid plexus cysts VATER associations Esophageal atresia, radial hypoplasia, renal dysplasia Del (4p) and Del (5p) Hypertelorism, IUGR, CHD Del (13 q) Hypertelorism, IUGR,CHD, hydrocephalus, small thumbs Del (18p) IUGR, holoprosencephaly Del (18q) Cleft lip, CHD, horseshoe kidney
  • 24. Environmental Factors Alcohol IUGR, hydrocephalus, CHD Amniopterin IUGR, hydrocephalus, neural tube defect, hypoplasia/frontal bone, cleft palate, broad nasal bridge, hypertelorism, CHD Hydantoin IUGR, hypertelorism, cleft lip, CHD, duodenal atresia, single umbilical artery Maternal phenylketonuria IUGR, CHD Rubella IUGR, CHD
  • 25. Abnormal Ultrasound Feature Skeletal Dysplasias Amniotic fluid volume and polyhydramnios Robert S, VATERS association Acromelia Ellis-van Creveld dysplasia, Poland sequence
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43. Gestation (weeks) <10 10–12 12–14 >14 Patients 19 34 65 26 Four chamber - 13 (37) 44 (68) 21 (81) Head - 13 (37) 43 (66) 16 (62) Spine - 5 (15) 28 (43) 8 (31) Stomach 2 (10) 19 (56) 62 (95) 24 (92) Kidneys - 5 (15) 38 (58) 14 (54) Bladder 3 (6) 14 (42) 52 (80) 23 (88)
  • 44.
  • 45.
  • 46.
  • 47.
  • 48. Take Home message • Adolesence health care • Premarital counselling • Marriage at approptiate age • Child bearing at appropriate age • Good anc • Good intrapatum care • Good pnc • Woman empowerment
  • 49. • Anomaly scan at 18to22k • Nowdays 3d or 4d usg at 10wk to14 • Cvs • Amniocentesis • Cordocentesis • If require opion of fetal medicine expert