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XanthogranulomatousXanthogranulomatous
PyelonephritisPyelonephritis
Rare severe chronic renal infectionRare severe chronic renal infection
Obstructive infective uropathy secondary toObstructive infective uropathy secondary to
calculicalculi
Lipid-laden macrophages - xanthoma cellsLipid-laden macrophages - xanthoma cells
Chronic clinical course of flank pain, feverChronic clinical course of flank pain, fever
and bacteriuria with malaise.and bacteriuria with malaise.
Retroperitoneal inflammatory reactionRetroperitoneal inflammatory reaction
Investigation;Investigation;
KUB - calculiKUB - calculi
CT Scan - renal mass with multiple smallCT Scan - renal mass with multiple small
abscessesabscesses
Management;Management;
Nephrectomy ± colectomy / splenectomyNephrectomy ± colectomy / splenectomy
Cutaneous FistulaCutaneous Fistula

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Xanthogranulomatous pyelonefritis

  • 1. XanthogranulomatousXanthogranulomatous PyelonephritisPyelonephritis Rare severe chronic renal infectionRare severe chronic renal infection Obstructive infective uropathy secondary toObstructive infective uropathy secondary to calculicalculi Lipid-laden macrophages - xanthoma cellsLipid-laden macrophages - xanthoma cells Chronic clinical course of flank pain, feverChronic clinical course of flank pain, fever and bacteriuria with malaise.and bacteriuria with malaise. Retroperitoneal inflammatory reactionRetroperitoneal inflammatory reaction
  • 2. Investigation;Investigation; KUB - calculiKUB - calculi CT Scan - renal mass with multiple smallCT Scan - renal mass with multiple small abscessesabscesses Management;Management; Nephrectomy ± colectomy / splenectomyNephrectomy ± colectomy / splenectomy Cutaneous FistulaCutaneous Fistula