The small intestine is adapted for efficient absorption of nutrients through several mechanisms: it has a large surface area due to numerous villi and microvilli that increase absorption area; the epithelial membrane is thin to facilitate diffusion; and a concentration gradient is maintained by transporting digested substances away from the villus via blood and lymphatic capillaries, allowing for continual absorption. Nutrients like glucose, amino acids, and water are absorbed directly into the bloodstream, while fatty acids and glycerol enter the lymphatic system to be recombined and absorbed.