No more fear from Injections! Discover it now! Felt nostalgic when Business Today published an article regarding the necessity and usefulness of Needlefree injections. Most probably it was published on May 10, 2013. He is the link: http://businesstoday.intoday.in/story/small-pharma-companies-in-niche-areas-of-health-care/1/194279.html

1. NEEDLE FREE
INJECTION
By
Kaushik Bandopadhyay
NSEC, BME

2. CLASSIFICATION
Needle free Injections can be classified
into two types based on their mechanism
of drug delivery:
1) Nano-Patch
2) Jet Pressure Needle free Injection

3. NANO-PATCH
The most modern form of drug delivery
through needle free system.
As the name suggests, this is a small
sized device having the size of a stamp
which has about 20,000 micro-projections
per square cm on its surface.

5. Application Methods
Drug delivery through Nano-Patch is done in
two ways:
1) Sand paper aided delivery
2) Iontophoresis enabled delivery

6. Sand paper aided delivery

7. Mechanism of Operation
The micro-projections containing
drug/vaccine delivers the drug/vaccine into
the epidermis.
The epidermis is rich of Langerhans cells
which are members of our Immune
system
These cells move to the nearest Lymph
node and display the antigen to the T-cells

8. T-cells specifically recognizes one type of
antigen and creates a corresponding antibody.
Once this recognition procedure is completed the
antibodies will provide immediate protection and
these cells will protect from getting the same
disease twice. Thereby providing life term of
protection.

10. Jet Pressured Needle free Injection
Devised in the year 2001 by The Medical
House and Bioject. This device has a
specialized nozzle through which the drug
is delivered.
A three component system comprising an
injection device, specially desgned nozzle
and air cartridge is present.

12. Mechanism of Operation
Instead of creating a puncture on the skin
surface, this device forces the drug
through skin pores by the help of air
pressure, thereby effectively delivering the
drug without the help of needle.

14. Advantages of using this
technology
 Painless procedure
 Relief to patients who have to be inoculated
many times in a day
 Efficient use of Vaccine
 Pandemic effective
 Zero contamination
 Better drug diffusion
 Zero disposal Hazard
 Ideal for developing countries

15. Popular Brands present
Internationally
 Biojectorr 2000
 Vitajet 3
 Cool click
 Serojet
 Iject
 Biovalve’s Miniject

16. Limitation of this technology
High pressure enabled delivery of drugs
by the Jet Pressured Needle free Injection
can damage fragile molecules beneath
our skin surface, especially the
Monoclonal antibodies.

17. Conclusion
Is the future Needle-free?
Developed countries have a Yes for this
question while from developing countries
the answer is not clear. Although this
technology is designed for such nations,
until a big pharmaceutical or
biotechnology company adopts it here, it
will continue to remain as a dream.

18. THANK YOU