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PAEDIATRIC
ANTIDIARRHOEAL
By,
Kamal Krishna Singh
1
7th April 2015
Presentation map
Introduction
Market Analysis
Prescription Analysis
Doctors Desk
Retailer Corner
Interpretation
2
Introduction
3
 Indian Pharmaceutical Market is occupied with more than 1850
brand of Antidiarrhoeal products.
 44 different types of combination & 17 different type of plain
(Single API).
 82% Brands Combination & 18% Brands Plain Formulations.
 91% from Domestic & 9% from MNC.
 Formulations : 4% Injectables, 24% Liquid and 72% Solid.
 In liquid formulation 30 ml is the most available quantity (71%)
followed by 60 ml (21%).
Market Analysis
All India Antidiarrhoeal Market (IMS: Oct13)
Particulates Value (Crs) Present Approximation
Sum of MAT OCT 13 1518.8 1550
Sum of MAT GR OCT 13 1.2% 1.5%
4
TOP 5 ANTIDIARRHOEAL BRANDS IN VALUE
BRAND MOLECULES COMPANY VAL OCT 13 GROWTH(%)
O2 OFLOXACIN + ORNIDAZOLE MEDLEY PHARMACEUTICALS 37 1.66
METROGYL METRONIDAZOLE JB CHEMICALS 30 24.34
ZENFLOX OZ OFLOXACIN + ORNIDAZOLE MANKIND PHARMACEUTICALS LTD. 28 -5.47
NORFLOX TZ
TINIDAZOLE +
NORFLOXACIN +
LACTOBACILLUS
CIPLA LTD. 27 -6.66
MESACOL MESALAZINE SUN PHARMACEUTICAL INDUSTRIES LTD 20 14.28
Market Analysis
5
ANTIDIARRHOEAL BRANDS (ABOVE 10 CRS) WITH MAXIMUM GROWTH
BRAND MOLECULES COMPANY VAL OCT 13 (Crs) GROWTH(%)
RIFAGUT RIFAXIMIN SUN PHARMACEUTICAL INDUSTRIES LTD 20 50
XYLISTIN COLISTINE CIPLA LTD. 15 48
ELDOPER LOPERAMIDE MICRO LABS LTD 12 30
SAAZ SULFASALAZINE IPCA LABORATORIES PVT LTD. 10 25
METROGYL METRONIDAZOLE JB CHEMICALS 30 24
ANTIDIARRHOEAL COMBINATION WITH MAXIMUM NO. OF PLAYERS
COMBINATION BRAND (LEADER) COMPANY NO. OF PLAYER
VAL OCT 13
(Crs)
OFLOXACIN + ORNIDAZOLE O2 MEDLEY PHARMACEUTICALS 394 37
CIPROFLOXACIN + TINIDAZOLE CIPLOX TZ CIPLA LTD. 209 20
PROBIOTIC MICROBES ENTEROGERMINA SANOFI 185 34
OFLOXACIN + TINIDAZOLE OFLOX TZ CIPLA LTD. 127 1
NORFLOXACIN+TINIDAZOLE TINIBA ZYDUS 102 1
Prescription Analysis (Paediatrician)
6
48
35
5 3 2 2
ZINC
PREPARATION
/DT/LIQ(L)
RACECADOTRIL
SACHET(L)
RIFAXIMIN(L)
RACECADOTRIL(
KT/DT)
RACECADOTRIL+
LYOPHYSACCHA
(L)
Others
Antidiarrhoeal Oral Liquid Vs % of Prescription
C marc-feb2015
For academic purpose
only
Prescription Analysis (Paediatrician)
7
33
11 6 5 4
40
Z&DDROPS[DRL-
WINTURA]
Z&DSYR[DRL-
WINTURA]
RACIGYLSB
SACHET
[MANKIND-DISC]
RALOPSACHET/
SYR[SALUDCARE
]
RACIGYLSACHET
[MANKIND-DISC]
Others
Different Antidiarrhoeal Oral Liquid Brands Vs % Prescription
C marc-feb2015
For academic purpose
only
Prescription Analysis (Paediatrician)
8
56
31
5 3 2 4
RACECADOTRIL
(S)
LOPERAMIDE(S)
RIFAXIMIN(S)
PEC.,KAO.WITH
ANTI-
DIAR.CB.(S)
FURAZOLIDON
&OTHERS(S)
Others
Antidiarrhoeal Oral Solid Vs % of Prescription
C marc-feb2015
For academic purpose
only
Prescription Analysis (Paediatrician)
9
23
11 10 8 8
41
RACIGYLKIDTAB
[MANKIND-DISC]
ZEDOTTCAPS[TPL
-VISTA]
RIDOLTAB[GUFIC
]
ANDIALTAB
[VERITAZ-VERI]
ENUFFCAPS
[HETERO-PH]
Others
Different Antidiarrhoeal Oral Solid Brands Vs % Prescription
C marc-feb2015
For academic purpose
only
Doctors Desk
10
Antidiarrhoeal treatment in children depends upon several factors.
 Age
 Body weight
 Severity
 Type of infection
 Others (ADR, suffering with other disease etc)
Antidiarrhoeal Oral Liquid: Issues -unpalatable, bitter taste, constipation &
dosage accuracy.
Most GP does not treat and refer to Paediatrician if the child age is below 2-3
years.
Safety & efficacy are the major concern while prescribing a brand.
Mostly go with brand of reputed company to avoid risk.
Retailer Corner
11
 Most of the prescription for Antidiarrhoeal formulation come
from GP if the age of patients is above 3-4 years followed by
Paediatrician if the age is below 2-3 years.
 Top selling formulation are Z & D Drops of DRL and O2 of
MEDLEY PHARMACEUTICALS in Antidiarrhoeal
formulations.
 Average Selling of O2 Sups is 15-16 bottle PM.
Interpretation
12
 Growth of Antidiarrhoeal Oral Solid (1.90%) is higher than Oral
Liquid (1.40%), however the market size of Antidiarrhoeal Oral
Liquid is 4 times higher than that of Solid; So focus should be
on Liquid Formulation.
 Demand of Antidiarrhoeal oral liquid or solid is highest during
march to june months followed by july to oct months.
 Maximum prescribed Antidiarrhoeal formulations are Z & D
Drops, O2 Sups and Racigyl kid tab.
 Promotion of Antidiarrhoeal high end product (serious) should
be targeted to Paediatrician only.
13

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Paediatric antidiarrhoeal market

  • 2. Presentation map Introduction Market Analysis Prescription Analysis Doctors Desk Retailer Corner Interpretation 2
  • 3. Introduction 3  Indian Pharmaceutical Market is occupied with more than 1850 brand of Antidiarrhoeal products.  44 different types of combination & 17 different type of plain (Single API).  82% Brands Combination & 18% Brands Plain Formulations.  91% from Domestic & 9% from MNC.  Formulations : 4% Injectables, 24% Liquid and 72% Solid.  In liquid formulation 30 ml is the most available quantity (71%) followed by 60 ml (21%).
  • 4. Market Analysis All India Antidiarrhoeal Market (IMS: Oct13) Particulates Value (Crs) Present Approximation Sum of MAT OCT 13 1518.8 1550 Sum of MAT GR OCT 13 1.2% 1.5% 4 TOP 5 ANTIDIARRHOEAL BRANDS IN VALUE BRAND MOLECULES COMPANY VAL OCT 13 GROWTH(%) O2 OFLOXACIN + ORNIDAZOLE MEDLEY PHARMACEUTICALS 37 1.66 METROGYL METRONIDAZOLE JB CHEMICALS 30 24.34 ZENFLOX OZ OFLOXACIN + ORNIDAZOLE MANKIND PHARMACEUTICALS LTD. 28 -5.47 NORFLOX TZ TINIDAZOLE + NORFLOXACIN + LACTOBACILLUS CIPLA LTD. 27 -6.66 MESACOL MESALAZINE SUN PHARMACEUTICAL INDUSTRIES LTD 20 14.28
  • 5. Market Analysis 5 ANTIDIARRHOEAL BRANDS (ABOVE 10 CRS) WITH MAXIMUM GROWTH BRAND MOLECULES COMPANY VAL OCT 13 (Crs) GROWTH(%) RIFAGUT RIFAXIMIN SUN PHARMACEUTICAL INDUSTRIES LTD 20 50 XYLISTIN COLISTINE CIPLA LTD. 15 48 ELDOPER LOPERAMIDE MICRO LABS LTD 12 30 SAAZ SULFASALAZINE IPCA LABORATORIES PVT LTD. 10 25 METROGYL METRONIDAZOLE JB CHEMICALS 30 24 ANTIDIARRHOEAL COMBINATION WITH MAXIMUM NO. OF PLAYERS COMBINATION BRAND (LEADER) COMPANY NO. OF PLAYER VAL OCT 13 (Crs) OFLOXACIN + ORNIDAZOLE O2 MEDLEY PHARMACEUTICALS 394 37 CIPROFLOXACIN + TINIDAZOLE CIPLOX TZ CIPLA LTD. 209 20 PROBIOTIC MICROBES ENTEROGERMINA SANOFI 185 34 OFLOXACIN + TINIDAZOLE OFLOX TZ CIPLA LTD. 127 1 NORFLOXACIN+TINIDAZOLE TINIBA ZYDUS 102 1
  • 6. Prescription Analysis (Paediatrician) 6 48 35 5 3 2 2 ZINC PREPARATION /DT/LIQ(L) RACECADOTRIL SACHET(L) RIFAXIMIN(L) RACECADOTRIL( KT/DT) RACECADOTRIL+ LYOPHYSACCHA (L) Others Antidiarrhoeal Oral Liquid Vs % of Prescription C marc-feb2015 For academic purpose only
  • 7. Prescription Analysis (Paediatrician) 7 33 11 6 5 4 40 Z&DDROPS[DRL- WINTURA] Z&DSYR[DRL- WINTURA] RACIGYLSB SACHET [MANKIND-DISC] RALOPSACHET/ SYR[SALUDCARE ] RACIGYLSACHET [MANKIND-DISC] Others Different Antidiarrhoeal Oral Liquid Brands Vs % Prescription C marc-feb2015 For academic purpose only
  • 8. Prescription Analysis (Paediatrician) 8 56 31 5 3 2 4 RACECADOTRIL (S) LOPERAMIDE(S) RIFAXIMIN(S) PEC.,KAO.WITH ANTI- DIAR.CB.(S) FURAZOLIDON &OTHERS(S) Others Antidiarrhoeal Oral Solid Vs % of Prescription C marc-feb2015 For academic purpose only
  • 9. Prescription Analysis (Paediatrician) 9 23 11 10 8 8 41 RACIGYLKIDTAB [MANKIND-DISC] ZEDOTTCAPS[TPL -VISTA] RIDOLTAB[GUFIC ] ANDIALTAB [VERITAZ-VERI] ENUFFCAPS [HETERO-PH] Others Different Antidiarrhoeal Oral Solid Brands Vs % Prescription C marc-feb2015 For academic purpose only
  • 10. Doctors Desk 10 Antidiarrhoeal treatment in children depends upon several factors.  Age  Body weight  Severity  Type of infection  Others (ADR, suffering with other disease etc) Antidiarrhoeal Oral Liquid: Issues -unpalatable, bitter taste, constipation & dosage accuracy. Most GP does not treat and refer to Paediatrician if the child age is below 2-3 years. Safety & efficacy are the major concern while prescribing a brand. Mostly go with brand of reputed company to avoid risk.
  • 11. Retailer Corner 11  Most of the prescription for Antidiarrhoeal formulation come from GP if the age of patients is above 3-4 years followed by Paediatrician if the age is below 2-3 years.  Top selling formulation are Z & D Drops of DRL and O2 of MEDLEY PHARMACEUTICALS in Antidiarrhoeal formulations.  Average Selling of O2 Sups is 15-16 bottle PM.
  • 12. Interpretation 12  Growth of Antidiarrhoeal Oral Solid (1.90%) is higher than Oral Liquid (1.40%), however the market size of Antidiarrhoeal Oral Liquid is 4 times higher than that of Solid; So focus should be on Liquid Formulation.  Demand of Antidiarrhoeal oral liquid or solid is highest during march to june months followed by july to oct months.  Maximum prescribed Antidiarrhoeal formulations are Z & D Drops, O2 Sups and Racigyl kid tab.  Promotion of Antidiarrhoeal high end product (serious) should be targeted to Paediatrician only.
  • 13. 13