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Synthetic Biology at BarcampRochester3

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Jason Morrison
Jason Morrison

A 30-minute overview of synthetic biology delivered April 2008.

Technologie
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An Introduction to Synthetic Biology “Hacking DNA for Fun and Profit”
1. what? 2. applications 3. the tech 4. free and safe 5. go hack
1. what? 2. applications 3. the tech 4. free and safe 5. go hack
Engineering vs Science
Understanding, Models Science Engineering Artifacts (cells)
Synthetic Biology
Synthetic Biology = GeneticEngineering++
1. Recombinant DNA 2. PCR 3. Automated sequencing
1. Recombinant DNA 2. PCR 3. Automated sequencing 4. Automated construction 5. Standardization 6. Abstraction
Specifications Testing/Validation Design Standard Engineering Implementation Practice Modelling The Imperial College of London, iGEM 2006
Specifications Design Modelling Implementation Testing Start! Specifications oscillator Based on Lotka-Volterra Modelling Lotka-Volterra Based on Quorum Sensing Modelling Full system Specifications test constructs Design test constructs Modelling Test construct Build test constructs Characterized test constructs Modelling characterized sys Build full system Characterized Full system Our Goal! The Imperial College of London, iGEM 2006
1. what? 2. applications 3. the tech 4. free and safe 5. go hack
Biofuels
Bioremediation
Medicine
Space ISRU
1. what? 2. applications 3. the tech 4. free and safe 5. go hack
$1/bp, 4wk
e. coli: 4k you and me: 3gbp
Standardzied Assembly
Common Signal Carrier
Polymerase Operations per Second
Characterization
Composition & Abstraction
http://www.ccbi.cam.ac.uk/iGEM2006/index.php/Description
http://www.ccbi.cam.ac.uk/iGEM2006/index.php/Description
1. what? 2. applications 3. the tech 4. free and safe 5. go hack
Legal Frameworks
Human Factors
1. what? 2. applications 3. the tech 4. free and safe 5. go hack
http://www.igem.org
http://parts.mit.edu
http://www.openwetware.org
Questions!
diybio.org igem.org parts.mit.edu openwetware.org biohack.sf.net

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Synthetic Biology at BarcampRochester3