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Nutrients:
Ingestion to
  Energy
Metabolism

 Chapter 2
What happens to nutrients after they are
              ingested?

• Two types of digestion
  – Mechanical: includes chewing, peristalsis
  – Chemical: includes digestion enzymes
• Absorption
• Transport
• Assimilation and/or energy production
Digestion: Anatomy and Functions of the
            Digestive System
Mouth to anus is 25 ft!

•   Mouth (oral cavity)
•   Esophagus
•   Stomach
•   Small intestine
•   Large intestine
•   Rectum
Digestion: Salivary Glands


• Salivary glands
   – See figure to right
• Secrete saliva
   – Moistens food
   – Contains enzymes
Digestion: Stomach
• Muscular organ
• Primary function:
  digestion
• Major secretions
   – Hydrochloric acid
     to unravel proteins
   – Mucus to protect
     stomach tissue from
     acid.
   – Digestive enzymes
Digestion and Absorption:
               Small Intestine
• Duodenum
   – Majority of digestion
     occurs here
• Jejunum
   – Little digestion
   – Absorption
• Ileum
   – Absorption
Absorption: Surface of Small Intestine

•   Convoluted interior
•   Villi
•   Microvilli
•   Result: Increased
    surface area for
    absorption
Absorption: Large Intestine
• Colon
   – Ascending
   – Transverse
   – Descending
• Rectum
• Anus
• Some absorption
   – Water
   – Sodium
   – Chloride
   – Potassium
   – Vitamin K
Absorption: Mechanisms
•   Passive diffusion – move from high to low
    concenration
•   Facilitated diffusion- move from high to low
    concentration carried by protein carrier.
•   Active transport – Concentration gradient not a
    factor.
•   Endocytosis
Absorption: Mechanisms
  •   Passive diffusion
  •   Facilitated diffusion
  •   Active transport
  •   Endocytosis
Absorption of Nutrients

                 Review this figure
                 to see where along
                 the GI tract
                 individual
                 nutrients are
                 absorbed.
Carbohydrates: Digestion
• Mouth
   – Mastication
     (chewing)
   – Amylase
• Stomach
   – Churning
   – Acid
• Small intestine
   – Sugar enzymes
• Large intestine
   – Bacteria
Carbohydrates: Absorption

• Most absorption occurs
  in small intestine
• Mechanisms
   – Facilitated diffusion
      • Fructose
   – Active transport
      • Glucose
      • Galactose
Carbohydrates: After Absorption

• Transport via blood
• Cellular uptake
   – Insulin
   – Glucose transporters
• Fates
   – Storage in liver or
     muscles as glycogen.
   – Conversion to
     adipose tissue (fat).
   – Energy
Fats: Digestion

• Mouth
   – Mastication
   – Lingual lipase        [Insert Fig. 2.12 here]
• Stomach
   – Gastric lipase
• Small intestines
   – Bile
   – Pancreatic lipase
   – Micelle formation
Fats: Absorption

• Occurs in small intestine
• Mechanism
   – Passive diffusion
• Very little fat makes it to
  large intestine
   – Steatorrhea
   – Crohn’s disease
   – Cystic fibrosis
Fats: After Absorption

• Transport
   – Lymph
      • Chylomicrons
   – Blood
• Cellular uptake
   – Lipoprotein lipase
• Fates
   – Storage
   – Energy
Proteins: Digestion
• Mouth
   • Mastication
• Stomach
   • Churning
   • Acid Denaturation: acid unravels proteins so
     peptide bonds can be cleaved by enzymes. Very
     important function of the stomach.
• Small intestine
   • Proteases
   • Peptidases
Proteins: Absorption
• Occurs in small intestine
• Mechanism
  – Facilitated diffusion
  – Active transport
• Very little makes it to large intestine
Proteins: Absorption
     AMINO ACID SUPPLEMENTATION
               CAUTION
•   Carrier proteins are responsible for facilitating absorption of amino
    acids.
•   Similar amino acids share the same active transport systems and
    protein carriers.
•   Taking amino acid supplements containing large amounts of single
    amino acids can affect the absorption of other amino acids if they
    share the same transport carrier.
•   If an athlete takes a large amount of a single amino acid this may
    result in overabsorption of that amino acid at the expense of another
    amino acid.
Proteins: After Absorption
•   Transport
     – Blood
•   Become part of amino acid pool
•   Fates
     – Body proteins such as
        muscle, enzymes,
        hormones.
     – Conversion to body fat.
     – Energy : Used for energy
        only when carbohydrate is
        not available fuel source.
        Not preferred fuel source as
        it has more important and
        essential roles in body.
Cellular Protein Synthesis


• Transcription
   – DNA
   – mRNA
• Translation
   – Transfer RNA
   – Amino acids
Vitamins, Minerals, and Water
• Digestion causes release from foods
• Absorption occurs in small and large intestines
What is energy?


• It is the entity that
  enables our bodies to
  perform work.
• It has no shape.
• It has no physical mass.
• Our bodies rely on
  chemical energy.


                                    Photo © Photodisc
What is the body’s source of energy?


• Macronutrients
   – Carbohydrates
   – Fats
   – Proteins
• Body’s direct energy
  source
   – Adenosine
     triphosphate (ATP)
Adenosine Triphosphate (ATP)


• Body’s energy source
• Two high-energy
  bonds
• Other phosphates
   – ADP
   – AMP
Cell Structure and Organelles Necessary
          for ATP Production
What are the three energy systems?


• Phosphagen System

• Anaerobic Energy System

• Aerobic Energy System
Comparison of the Three Energy Systems
Metabolic Pathways
Energy Nutrients
Cellular ATP Production:
 The Metabolic Factory
Phosphagen Energy System

• Stores of high-energy
  phosphates
   – ATP
   – Creatine phosphate
     (CP)
• Also known as:
   – Immediate energy
     system
   – ATP-CP system
Anaerobic Energy System


• Involves only
  carbohydrates
• Does not require oxygen
• Also known as:
   – Anaerobic glycolysis
Aerobic Energy System


• Involves all
  macronutrients
• Requires oxygen
• Also known as:
   – Oxidative system
Energy System Contributions to
       Activities of Varying Intensity


The small storage pool
of ATP is the source of
energy whenever
instantaneous energy is
needed.
Energy System Contributions to
       Activities of Varying Intensity


During short bursts of
intense activity (i.e.,
100m run), the
phosphagen system is
the main energy system
that supplies the ATP
pool.
Energy System Contributions to
       Activities of Varying Intensity


During longer lasting
sprint activities of lower
intensity (i.e., 800m
run), the main supplier
is the anaerobic system
with help from the
phosphagen and aerobic
systems.
Energy System Contributions to
        Activities of Varying Intensity


During longer lasting
activities of even lower
intensity (i.e., mile run),
the main supplier
becomes the aerobic
system with help from
the anaerobic system.
Energy System Contributions to
       Activities of Varying Intensity


During long lasting
activities of low
intensity (i.e., any
sustainable activity), the
main supplier becomes
the aerobic system with
minimal help from the
other systems.
Summary:
  The Energy Systems Work
Together to Meet ATP Demand
How does carbohydrate intake impact
         protein metabolism?

• Carbohydrates are an
  important energy
  source.
• Low CHO results in
  muscle protein
  breakdown.
• Gluconeogenesis.

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Sports Nutrition_Chapter 2_Nutrients

  • 1. Nutrients: Ingestion to Energy Metabolism Chapter 2
  • 2. What happens to nutrients after they are ingested? • Two types of digestion – Mechanical: includes chewing, peristalsis – Chemical: includes digestion enzymes • Absorption • Transport • Assimilation and/or energy production
  • 3. Digestion: Anatomy and Functions of the Digestive System Mouth to anus is 25 ft! • Mouth (oral cavity) • Esophagus • Stomach • Small intestine • Large intestine • Rectum
  • 4. Digestion: Salivary Glands • Salivary glands – See figure to right • Secrete saliva – Moistens food – Contains enzymes
  • 5. Digestion: Stomach • Muscular organ • Primary function: digestion • Major secretions – Hydrochloric acid to unravel proteins – Mucus to protect stomach tissue from acid. – Digestive enzymes
  • 6. Digestion and Absorption: Small Intestine • Duodenum – Majority of digestion occurs here • Jejunum – Little digestion – Absorption • Ileum – Absorption
  • 7. Absorption: Surface of Small Intestine • Convoluted interior • Villi • Microvilli • Result: Increased surface area for absorption
  • 8. Absorption: Large Intestine • Colon – Ascending – Transverse – Descending • Rectum • Anus • Some absorption – Water – Sodium – Chloride – Potassium – Vitamin K
  • 9. Absorption: Mechanisms • Passive diffusion – move from high to low concenration • Facilitated diffusion- move from high to low concentration carried by protein carrier. • Active transport – Concentration gradient not a factor. • Endocytosis
  • 10. Absorption: Mechanisms • Passive diffusion • Facilitated diffusion • Active transport • Endocytosis
  • 11. Absorption of Nutrients Review this figure to see where along the GI tract individual nutrients are absorbed.
  • 12. Carbohydrates: Digestion • Mouth – Mastication (chewing) – Amylase • Stomach – Churning – Acid • Small intestine – Sugar enzymes • Large intestine – Bacteria
  • 13. Carbohydrates: Absorption • Most absorption occurs in small intestine • Mechanisms – Facilitated diffusion • Fructose – Active transport • Glucose • Galactose
  • 14. Carbohydrates: After Absorption • Transport via blood • Cellular uptake – Insulin – Glucose transporters • Fates – Storage in liver or muscles as glycogen. – Conversion to adipose tissue (fat). – Energy
  • 15. Fats: Digestion • Mouth – Mastication – Lingual lipase [Insert Fig. 2.12 here] • Stomach – Gastric lipase • Small intestines – Bile – Pancreatic lipase – Micelle formation
  • 16. Fats: Absorption • Occurs in small intestine • Mechanism – Passive diffusion • Very little fat makes it to large intestine – Steatorrhea – Crohn’s disease – Cystic fibrosis
  • 17. Fats: After Absorption • Transport – Lymph • Chylomicrons – Blood • Cellular uptake – Lipoprotein lipase • Fates – Storage – Energy
  • 18. Proteins: Digestion • Mouth • Mastication • Stomach • Churning • Acid Denaturation: acid unravels proteins so peptide bonds can be cleaved by enzymes. Very important function of the stomach. • Small intestine • Proteases • Peptidases
  • 19. Proteins: Absorption • Occurs in small intestine • Mechanism – Facilitated diffusion – Active transport • Very little makes it to large intestine
  • 20. Proteins: Absorption AMINO ACID SUPPLEMENTATION CAUTION • Carrier proteins are responsible for facilitating absorption of amino acids. • Similar amino acids share the same active transport systems and protein carriers. • Taking amino acid supplements containing large amounts of single amino acids can affect the absorption of other amino acids if they share the same transport carrier. • If an athlete takes a large amount of a single amino acid this may result in overabsorption of that amino acid at the expense of another amino acid.
  • 21. Proteins: After Absorption • Transport – Blood • Become part of amino acid pool • Fates – Body proteins such as muscle, enzymes, hormones. – Conversion to body fat. – Energy : Used for energy only when carbohydrate is not available fuel source. Not preferred fuel source as it has more important and essential roles in body.
  • 22. Cellular Protein Synthesis • Transcription – DNA – mRNA • Translation – Transfer RNA – Amino acids
  • 23. Vitamins, Minerals, and Water • Digestion causes release from foods • Absorption occurs in small and large intestines
  • 24. What is energy? • It is the entity that enables our bodies to perform work. • It has no shape. • It has no physical mass. • Our bodies rely on chemical energy. Photo © Photodisc
  • 25. What is the body’s source of energy? • Macronutrients – Carbohydrates – Fats – Proteins • Body’s direct energy source – Adenosine triphosphate (ATP)
  • 26. Adenosine Triphosphate (ATP) • Body’s energy source • Two high-energy bonds • Other phosphates – ADP – AMP
  • 27. Cell Structure and Organelles Necessary for ATP Production
  • 28. What are the three energy systems? • Phosphagen System • Anaerobic Energy System • Aerobic Energy System
  • 29. Comparison of the Three Energy Systems
  • 32. Cellular ATP Production: The Metabolic Factory
  • 33. Phosphagen Energy System • Stores of high-energy phosphates – ATP – Creatine phosphate (CP) • Also known as: – Immediate energy system – ATP-CP system
  • 34. Anaerobic Energy System • Involves only carbohydrates • Does not require oxygen • Also known as: – Anaerobic glycolysis
  • 35. Aerobic Energy System • Involves all macronutrients • Requires oxygen • Also known as: – Oxidative system
  • 36. Energy System Contributions to Activities of Varying Intensity The small storage pool of ATP is the source of energy whenever instantaneous energy is needed.
  • 37. Energy System Contributions to Activities of Varying Intensity During short bursts of intense activity (i.e., 100m run), the phosphagen system is the main energy system that supplies the ATP pool.
  • 38. Energy System Contributions to Activities of Varying Intensity During longer lasting sprint activities of lower intensity (i.e., 800m run), the main supplier is the anaerobic system with help from the phosphagen and aerobic systems.
  • 39. Energy System Contributions to Activities of Varying Intensity During longer lasting activities of even lower intensity (i.e., mile run), the main supplier becomes the aerobic system with help from the anaerobic system.
  • 40. Energy System Contributions to Activities of Varying Intensity During long lasting activities of low intensity (i.e., any sustainable activity), the main supplier becomes the aerobic system with minimal help from the other systems.
  • 41. Summary: The Energy Systems Work Together to Meet ATP Demand
  • 42. How does carbohydrate intake impact protein metabolism? • Carbohydrates are an important energy source. • Low CHO results in muscle protein breakdown. • Gluconeogenesis.