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Seizure Classification
Kelly Caravetta, CRNP
What is happening with a seizure?
http://www.istockphoto.com/search/text/neurons/filetypes/photos,illustrations.video/source/basic#185a52
76
What is happening with a seizure?
Abnormal electrical activity in the brain
causing a sudden uncontrolled event
Periods of sustained hyperactivity in the brain
Seizures look different, depending upon what
part of the brain they affect
The Brain
Brain is divided into 2 hemispheres
and 4 lobes
http://commons.wikimedia.org/wiki/File:Cerebral-lobes.png
The 4 lobes of the brain
What do they do?
Frontal
Parietal
Temporal
Occipital
http://www.adamimages.com/illustration/Browse/1/B
The 4 lobes of the brain
Frontal lobes- planning and control of
movements
Parietal lobes- deal with sensation
Temporal lobes- important for learning,
memory and emotions
Occipital lobes- centers of brain that allow
us to see
Classifications
Type of seizure
Type of epilepsy (or syndrome)
(our focus is on seizure types)
Importance of classification
Benefit of experience gained in treatment of
same type of seizures/epilepsy in past
Certain drugs do not work for one seizure type
or syndrome
How (type of) epilepsy will develop over the
years
Seizure types
The main sub-categories are:
Focal (partial) seizures
Generalized seizures
Status-Epilepticus
Diagnosis often confused for epilepsy:
Non-epileptic seizures
Focal (partial seizures)
http://www.uth.tmc.edu/reynolds//soundbytes/recogSeiz.html
What are focal (partial) seizures?
Epileptic activity only affects one part of the brain
The place in the brain where seizures start is
called the “focus”
An epileptic focus can be anywhere in the brain.
Can be with or without impairment of consciousness
Types of focal (partial) seizures
Without impairment of consciousness (simple
partial)
With impairment of consciousness (complex
partial)
Evolving to both hemispheres or convulsive
seizure
(secondarily generalized)
Focal seizures without loss of
awareness (simple partial)
People retain awareness and ablility to recall
-motor or autonomic symptoms- movements of
part of the body, nausea or upset stomach
-sensory or psychic symptoms (aura)-
numbness, tingling, pain, smell, deja-vu,
jamais-vu
http://zidbits.com/2011/08/what-is-the-opposite-of-deja-vu/
Focal seizures with impairment of
consciousness (complex-partial)
Consciousness is reduced or lost
Occur most commonly in the temporal and
frontal lobes
With sensory or motor symptoms
– ex)lip smacking, clear throat, fiddle with
clothes, laugh, staring
Actions purposeless, look as if behaving
strangely
Focal seizures with impairment of
consciousness (complex partial, con't)
Seizures look different in everyone, but
repeat same behavior in their seizures
Lasts about 2 minutes or less
Some experience an aura prior; confused and
tired afterwards
-Simple partial seizure followed by impairment
of consciousness
-With impairment of consciousness on onset
Focal (partial) seizures with
impairment of consciousness
Evolving to both sides of the brain
(secondarily generalized)
Starts from one area of the brain, then
involves both hemispheres
Simple partial and/or complex partial seizure
progressing to a generalized seizure
http://graphicwitness.medical.
illustration.com,(Generalized
Seizures, exh 49300c)
Some types of focal epilepsy
Temporal lobe epilepsy
http://www.wiredtowninthemovie.com/mindtrip-xml.html
Frontal lobe epilepsy
http://www.wiredtowninthemovie.com/mindtrip-xml.html
Temporal lobe epilepsy
Seizures arise from the temporal lobe(s)
Most frequent type of focal epilepsies,
constitutes 30-35% of all epilepsies
(Panayiotopoulos,2010)
Possible cause- defect or scar in temporal
lobe
Onset often in childhood or early adulthood
Temporal lobe epilepsy
Symptoms:
Often aura, experience feelings,
emotions, sensation rising up from stomach,
hear voices, odd smell or taste
Lip smacking, hand rubbing, shouting, laughing or
fiddling with buttons on clothes
Seizures usually last 1-2 minutes
Confusion and headache afterwards
Frontal lobe epilepsy
Recurring seizures that arise in the frontal lobe
Second most common focal epilepsy
Possible causes: tumor, head trauma, birth
defect or can be genetic
Seizures can be with or without consciousness
Have a tendency to occur in sleep
Mistaken as a non-epileptic seizure or sleep disorder
Frontal lobe epilepsy
Symptoms:
May start with an aura
Involve laughing, crying or shouting
Weakness or inability to use
certain muscles (trouble speaking)
Can be aware of loss of control of arms & legs
Seizures in one person are similar
Generalized seizures
Epileptic activity affects both hemispheres of
the brain from onset of seizure
http://www.lhsc.on.ca/eeg/epilepsy.htm
Types of generalized seizures
Tonic-clonic seizure
Tonic
Clonic
Myoclonic seizure
Absence seizure
Atonic
Tonic-Clonic Seizures
Consciousness is lost, no recollection
Body stiffens, may fall, scream
Arm and leg jerking
Frothing at the mouth
Incontinence
Bitten tongue
May occur in sleep or upon awakening
http://quizlet.com/13025999/neurology-disorders-of-consciousness-flash-cards/
Tonic and Clonic seizures
Tonic-
-muscles stiffen,
-Consciousness lost
-affects whole or part of body
-can last 10-20 seconds
Clonic-
-consist of rhythmic jerking
-various ages
Myoclonic seizures
Brief jerks typically occur 1-2 hours from
waking up
Usually less than a second
One or many in a short period
May drop an object
Myoclonic seizures
Abnormal movements of arms/shoulder both
sides, sometimes entire body
May fall and injure themselves
Sometimes triggered by flashing lights
example: Juvenile Myoclonic Epilepsy
Absence seizures
Short interruption of consciousness
With staring
Brief 5-12 seconds
So brief, may escape detection
More common in children than adults
No warning or after-effect
Atonic seizures
Atonic means “without tone”
Head nods, neck muscles suddenly lose
tension, fall
Can injure themselves when they fall, helmet
for protection
Often begin in childhood and last into
adulthood
Status Epilepticus
One seizure quickly follows another
Any seizure can develop into status epilepticus
(tonic-clonic status, absence status, complex partial
status)
Tonic-clonic (convulsive) status is a medical
emergency
Tonic-clonic seizures longer then 5 minutes or
happens again after a short break, call an ambulance
Non-epileptic seizures
May look like epileptic seizures
Not caused by electrical disruptions in brain
Tend to change in character over time
Longer than epileptic seizures
Non-epileptic seizures
Occur only in wakefulness
Anti-epileptic drugs do not help
30% of patients with epileptic seizures also
suffer from non-epileptic seizures
(Panayiotopoulos, 2010)
First Aid
Stay calm
Do not insert anything into the person's
mouth
Keep person safe, remove dangerous
objects
Do not restrain
First Aid
Turn the person on their side, loosen tight
clothing
Remain with person after seizure
Call 911 if seizure (convulsive) lasts longer
then 5 minutes or second seizure without
recovery from the first
First Aid
http://unitedtruthseekers.com/profiles/blogs/how-to-help-with-seizures
Medical attention required
If a person is pregnant or diabetic
If injured themselves during the seizure
First time seizure
Seizure occurred in water
If seizures continue beyond 5 minutes
Questions?
http://www.jpole-antenna.com/2013/03/29lightning-protection-for-antennas/
References
Epilepsy Foundation. (2009). Types of Seizures.
Retrieved March 18th, 2013 from
http://www.epilepsyfoundation.org/get
involved/upload/181TOS.pdf.
Epilepsy.com. (n.d.). New Terms And
Concepts For Seizures And Epilepsy.
Retrieved April 1st, 2013 from
http://www.epilepsy.com/epilepsy/new-terms-
concepts-for-seizures-and-epilepsy.
References
Netter, Frank H., n.d., Absence Seizures
Retrieved April 1st, 2013 from
http:/www.netterimages.com/image/1257.htm.
Netter, Frank H., n.d., Complex Partial
Seizures. Retrieved April 1st, 2013 from
http://www.netterimages.com/image/12156.
htm
Panayiotopoulos, C.P.,(2010). A Clinical
Guide to Epileptic Syndromes and Their
Treatment. London, UK: Springer
Healthcare,Ltd.
References
Reuber, M., Schahter, S., Elger, C., Altrup, U.
(2009). Epilepsy Explained. New York, NY:
Oxford University Press.
Shorvon, S., Guerrini, R., Cook, M., Lhatoo,
S., Kennard, C. (2013). Epilepsy and
Epileptic Seizures. Oxford, UK: Oxford
UniversityPress.

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Seizure Classification

  • 2. What is happening with a seizure? http://www.istockphoto.com/search/text/neurons/filetypes/photos,illustrations.video/source/basic#185a52 76
  • 3. What is happening with a seizure? Abnormal electrical activity in the brain causing a sudden uncontrolled event Periods of sustained hyperactivity in the brain Seizures look different, depending upon what part of the brain they affect
  • 4. The Brain Brain is divided into 2 hemispheres and 4 lobes http://commons.wikimedia.org/wiki/File:Cerebral-lobes.png
  • 5. The 4 lobes of the brain What do they do? Frontal Parietal Temporal Occipital http://www.adamimages.com/illustration/Browse/1/B
  • 6. The 4 lobes of the brain Frontal lobes- planning and control of movements Parietal lobes- deal with sensation Temporal lobes- important for learning, memory and emotions Occipital lobes- centers of brain that allow us to see
  • 7. Classifications Type of seizure Type of epilepsy (or syndrome) (our focus is on seizure types)
  • 8. Importance of classification Benefit of experience gained in treatment of same type of seizures/epilepsy in past Certain drugs do not work for one seizure type or syndrome How (type of) epilepsy will develop over the years
  • 9. Seizure types The main sub-categories are: Focal (partial) seizures Generalized seizures Status-Epilepticus Diagnosis often confused for epilepsy: Non-epileptic seizures
  • 11. What are focal (partial) seizures? Epileptic activity only affects one part of the brain The place in the brain where seizures start is called the “focus” An epileptic focus can be anywhere in the brain. Can be with or without impairment of consciousness
  • 12. Types of focal (partial) seizures Without impairment of consciousness (simple partial) With impairment of consciousness (complex partial) Evolving to both hemispheres or convulsive seizure (secondarily generalized)
  • 13. Focal seizures without loss of awareness (simple partial) People retain awareness and ablility to recall -motor or autonomic symptoms- movements of part of the body, nausea or upset stomach -sensory or psychic symptoms (aura)- numbness, tingling, pain, smell, deja-vu, jamais-vu http://zidbits.com/2011/08/what-is-the-opposite-of-deja-vu/
  • 14. Focal seizures with impairment of consciousness (complex-partial) Consciousness is reduced or lost Occur most commonly in the temporal and frontal lobes With sensory or motor symptoms – ex)lip smacking, clear throat, fiddle with clothes, laugh, staring Actions purposeless, look as if behaving strangely
  • 15. Focal seizures with impairment of consciousness (complex partial, con't) Seizures look different in everyone, but repeat same behavior in their seizures Lasts about 2 minutes or less Some experience an aura prior; confused and tired afterwards -Simple partial seizure followed by impairment of consciousness -With impairment of consciousness on onset
  • 16. Focal (partial) seizures with impairment of consciousness
  • 17. Evolving to both sides of the brain (secondarily generalized) Starts from one area of the brain, then involves both hemispheres Simple partial and/or complex partial seizure progressing to a generalized seizure http://graphicwitness.medical. illustration.com,(Generalized Seizures, exh 49300c)
  • 18. Some types of focal epilepsy Temporal lobe epilepsy http://www.wiredtowninthemovie.com/mindtrip-xml.html Frontal lobe epilepsy http://www.wiredtowninthemovie.com/mindtrip-xml.html
  • 19. Temporal lobe epilepsy Seizures arise from the temporal lobe(s) Most frequent type of focal epilepsies, constitutes 30-35% of all epilepsies (Panayiotopoulos,2010) Possible cause- defect or scar in temporal lobe Onset often in childhood or early adulthood
  • 20. Temporal lobe epilepsy Symptoms: Often aura, experience feelings, emotions, sensation rising up from stomach, hear voices, odd smell or taste Lip smacking, hand rubbing, shouting, laughing or fiddling with buttons on clothes Seizures usually last 1-2 minutes Confusion and headache afterwards
  • 21. Frontal lobe epilepsy Recurring seizures that arise in the frontal lobe Second most common focal epilepsy Possible causes: tumor, head trauma, birth defect or can be genetic Seizures can be with or without consciousness Have a tendency to occur in sleep Mistaken as a non-epileptic seizure or sleep disorder
  • 22. Frontal lobe epilepsy Symptoms: May start with an aura Involve laughing, crying or shouting Weakness or inability to use certain muscles (trouble speaking) Can be aware of loss of control of arms & legs Seizures in one person are similar
  • 23. Generalized seizures Epileptic activity affects both hemispheres of the brain from onset of seizure http://www.lhsc.on.ca/eeg/epilepsy.htm
  • 24. Types of generalized seizures Tonic-clonic seizure Tonic Clonic Myoclonic seizure Absence seizure Atonic
  • 25. Tonic-Clonic Seizures Consciousness is lost, no recollection Body stiffens, may fall, scream Arm and leg jerking Frothing at the mouth Incontinence Bitten tongue May occur in sleep or upon awakening http://quizlet.com/13025999/neurology-disorders-of-consciousness-flash-cards/
  • 26. Tonic and Clonic seizures Tonic- -muscles stiffen, -Consciousness lost -affects whole or part of body -can last 10-20 seconds Clonic- -consist of rhythmic jerking -various ages
  • 27. Myoclonic seizures Brief jerks typically occur 1-2 hours from waking up Usually less than a second One or many in a short period May drop an object
  • 28. Myoclonic seizures Abnormal movements of arms/shoulder both sides, sometimes entire body May fall and injure themselves Sometimes triggered by flashing lights example: Juvenile Myoclonic Epilepsy
  • 29. Absence seizures Short interruption of consciousness With staring Brief 5-12 seconds So brief, may escape detection More common in children than adults No warning or after-effect
  • 30. Atonic seizures Atonic means “without tone” Head nods, neck muscles suddenly lose tension, fall Can injure themselves when they fall, helmet for protection Often begin in childhood and last into adulthood
  • 31. Status Epilepticus One seizure quickly follows another Any seizure can develop into status epilepticus (tonic-clonic status, absence status, complex partial status) Tonic-clonic (convulsive) status is a medical emergency Tonic-clonic seizures longer then 5 minutes or happens again after a short break, call an ambulance
  • 32. Non-epileptic seizures May look like epileptic seizures Not caused by electrical disruptions in brain Tend to change in character over time Longer than epileptic seizures
  • 33. Non-epileptic seizures Occur only in wakefulness Anti-epileptic drugs do not help 30% of patients with epileptic seizures also suffer from non-epileptic seizures (Panayiotopoulos, 2010)
  • 34. First Aid Stay calm Do not insert anything into the person's mouth Keep person safe, remove dangerous objects Do not restrain
  • 35. First Aid Turn the person on their side, loosen tight clothing Remain with person after seizure Call 911 if seizure (convulsive) lasts longer then 5 minutes or second seizure without recovery from the first
  • 37. Medical attention required If a person is pregnant or diabetic If injured themselves during the seizure First time seizure Seizure occurred in water If seizures continue beyond 5 minutes
  • 39. References Epilepsy Foundation. (2009). Types of Seizures. Retrieved March 18th, 2013 from http://www.epilepsyfoundation.org/get involved/upload/181TOS.pdf. Epilepsy.com. (n.d.). New Terms And Concepts For Seizures And Epilepsy. Retrieved April 1st, 2013 from http://www.epilepsy.com/epilepsy/new-terms- concepts-for-seizures-and-epilepsy.
  • 40. References Netter, Frank H., n.d., Absence Seizures Retrieved April 1st, 2013 from http:/www.netterimages.com/image/1257.htm. Netter, Frank H., n.d., Complex Partial Seizures. Retrieved April 1st, 2013 from http://www.netterimages.com/image/12156. htm Panayiotopoulos, C.P.,(2010). A Clinical Guide to Epileptic Syndromes and Their Treatment. London, UK: Springer Healthcare,Ltd.
  • 41. References Reuber, M., Schahter, S., Elger, C., Altrup, U. (2009). Epilepsy Explained. New York, NY: Oxford University Press. Shorvon, S., Guerrini, R., Cook, M., Lhatoo, S., Kennard, C. (2013). Epilepsy and Epileptic Seizures. Oxford, UK: Oxford UniversityPress.