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What Your Congregants Should Know Chicago Center for Jewish Genetic Disorders & Children’s Memorial Hospital Jewish Genetic Disorders:
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Ashkenazi Jewish genetic disorders represent a varied group of conditions
  Genetics ,[object Object],[object Object],[object Object],[object Object],[object Object]
What is a genetic mutation and how does it lead to disease? ,[object Object],[object Object],[object Object]
Many of the Ashkenazi Jewish genetic disorders are inherited in a   recessive   fashion When both parents are carriers for the same disorder, they have a 25% chance in each pregnancy of having an affected child.
Facts about   carriers   of recessive genetic disorders ,[object Object],[object Object],[object Object],[object Object]
Ethnicity ,[object Object],[object Object],[object Object],[object Object],& Disease Judaism is not only a religion and culture, but also a distinct ethnicity.
Why does ethnicity determine disease risk? Founder Effect ,[object Object],[object Object],[object Object]
For what diseases are   Sephardic   Jews at increased risk? ,[object Object],[object Object],[object Object],[object Object]
What disorders are   Ashkenazi   Jews at increased risk for? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
*Important note about the disorders ,[object Object]
To whom should screening be offered? ,[object Object],[object Object],[object Object]
What options are available to couples found to be at risk? ,[object Object],[object Object],[object Object],[object Object],[object Object]
How successful is carrier screening?  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Incidence of Classical Tay-Sachs disease in the U.S. and Canada
A decrease in the number of affected individuals  DOES NOT  mean a decrease in carrier   frequency.
Why would someone choose not to be screened? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dor Yeshorim ,[object Object],[object Object],[object Object],[object Object]
For more information about carrier screening or to find a local genetic counselor, please visit www.jewishgenetics.org The Center is a cooperative effort of  Jewish United Fund/Jewish Federation of Metropolitan Chicago and  Children’s Memorial Hospital and is funded in part by the Michael Reese Health Trust.

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Jewish Genetic Disorders: What Your Congregants Should Know

  • 1. What Your Congregants Should Know Chicago Center for Jewish Genetic Disorders & Children’s Memorial Hospital Jewish Genetic Disorders:
  • 2.
  • 3.
  • 4.
  • 5. Many of the Ashkenazi Jewish genetic disorders are inherited in a recessive fashion When both parents are carriers for the same disorder, they have a 25% chance in each pregnancy of having an affected child.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15. Incidence of Classical Tay-Sachs disease in the U.S. and Canada
  • 16. A decrease in the number of affected individuals DOES NOT mean a decrease in carrier frequency.
  • 17.
  • 18.
  • 19. For more information about carrier screening or to find a local genetic counselor, please visit www.jewishgenetics.org The Center is a cooperative effort of Jewish United Fund/Jewish Federation of Metropolitan Chicago and Children’s Memorial Hospital and is funded in part by the Michael Reese Health Trust.

Hinweis der Redaktion

  1. E & S Presentation 2006
  2. E & S Presentation 2006
  3. E & S Presentation 2006
  4. E & S Presentation 2006
  5. E & S Presentation 2006
  6. E & S Presentation 2006
  7. E & S Presentation 2006