UCLA CTSI KL2 Translational Science Award Mitchell Wong, MD Director, KL2 Program

1. UCLA CTSI KL2
Translational Science
Award
Mitchell Wong, MD PhD
Director, KL2 Program

2. Award Overview
• Career development support for junior
faculty within the UCLA CTSI Consortium
• Interdisciplinary, translational science
(basic, clinical and HSR)
• Similar in structure to K08/K23 award

3. Support
• Annual award, renewable for up to 3-years
• Support
– $75k salary plus benefits
– $25k research support
– $4k for tuition or coursework
– $2k for travel
– $1500 for statistical support in addition to in-
kind support from DOM Stats

4. Eligibility
• Doctoral level research degree or professional
degree (with advanced research training)
• Faculty level title as of July 1, 2014 at a UCLA
CTSI Institution
• Commit 75% of effort to translational research
and aims of the KL2 (50% minimum for some
specialties like surgery)
• U.S. Citizen or non-citizen national, permanent
U.S. resident

5. Eligibility (Prior/Pending
Grants)
• May have had a small grant (R03, R21)
• May have had prior K12 funding (total K funding
cannot exceed 5 years)
• Cannot have:
– Prior or current PI of a NIH R01 or equivalent grant
(direct costs>$100k per year)
– Prior or current PI of a K08/K23 award
– Prior or current PI of a VA Career Development or R01
Equivalent grant
– PI of a pending K award application, pending R award in
similar area
– Current co-investigator funding on an R01/Project grant

6. Future Funding for KL2
• KL2 Awardees may apply for K08/K23 or VA CDAs
– Must relinquish KL2 if awardee receives NIH/VA CDA
– Total CDA funding (KL2 + individual CDA) cannot
exceed 5 years.
• KL2 Awardees may apply for R01, Program grants
– Must maintain 75% effort on KL2 in year 1
– May decrease to 50% effort in last 2 years of K support

7. Selection Criteria
1. Proposed research- Quality, innovation, significance,
feasibility, promise for future funding, relevance to
interdisciplinary, translational research
2. Candidate- Training, productivity, promise
3. Mentor- Track record in mentorship and research,
commitment to candidate
4. Educational Plan- Well described and planned, fit with
research plan, provides candidate with new skill set
5. (Environment)- Commitment from institution,
department/division, availability of support and
resources to conduct research and educational plan

8. Application Components
• Letter of intent- Name, mentor, title, biosketch, specific aims
(to help KL2 selection committee identify appropriate
reviewers)
• Application (6 pages)- Research, Education and Career Plan
• Mentor’s Letter (2 pages)
• Institutional Letter (2 pages) from department chair or division
chief
• Letters of support (2 max)
• Candidate’s CV and other support page
• Mentor’s Biosketch
• Budget and budget justification
• References
• Data and Safety Monitoring Plan (when applicable)
• Appendices allowable (e.g. letter of support for use of
equipment or data)

9. Timeline
• Letter of intent deadline February 3, 2014
• Application deadline February 24, 2014
• Awardees will be notified in late April
2014
• Grant start date July 1, 2014
• Research funds will not be released until
IRB approval received

10. Timeline
• Letter of intent deadline February 3, 2014
• Application deadline February 24, 2014
• Awardees will be notified in late April
2014
• Grant start date July 1, 2014
• Research funds will not be released until
IRB approval received