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Prepared By:   Mr. Jalaram Thakkar   M. Pharm . Pathophysiology of peptic ulcer Saturday, October 31, 2009
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Epidemiology   ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ETIOLOGY AND RISK FACTORS
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Acute Esophagitis & Gastritis
Gastric peptic ulcer:
Gastric peptic ulcer:
Gastric Ulcer
Duodenal Peptic Ulcer
Gastric Ulcer
Peptic ulcer - Endoscopy
[object Object],[object Object],Pathophysiology
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[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Metabolism of arachidonic acid after its release from membrane phospholipids. ASA, aspirin; HPETE, hydroperoxyeicosatetraenoic acid; NSAIDs, nonsteroidal antiinflammatory drugs; PG, prostaglandin.
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[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TREATMENT: Peptic Ulcer Disease   ,[object Object],[object Object],[object Object]
NONPHARMACOLOGIC THERAPY Eliminate or reduce…..  Psychological  stress ,  Cigarette smoking , and  The use of selective  NSAIDs
  PHARMACOLOGIC THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
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[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
H. Pylory induced peptic ulcer ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THANK YOU

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