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Coronary CTA.
August 23, 2014.
POOL SOCIETY WEEKEND
JAYANTH H KESHAVAMURTHY, M.D.
ASSISTANT PROFESSOR OF RADIOLOGY
GEORGIA REGENTS UNIVERSITY.
1. Question
 An overweight man had CAC SCORE OF 500 last
year. He has made significant life style changes
since that time. He is now requesting a
reevalauation of his cardiovascular risk. What
would you recommend?
 A. Coronary CTA with CAC score.
 B. Coronary CTA without CAC score.
 C. CAC score only.
 D. Neither Coronary CTA nor CAC score.
Answer
D.
TECHNIQUE
 Prospective ECG triggered.
 120kVP
 Slice Collimation 2.5 -3mm.
 Medium sharp reconstruction kernel without
edge enhancement- provides moderate image
noise.
TECHNIQUE
 Z axis from carina to base of heart.
 FOV is 250 mm.
INDICATIONS
 Risk stratification in asymptomatic individual.
 With intermediate Framingham Risk Score.
USEFULNESS
 Incremental prognostic information.
 Independent risk assessment over
Framingham risk evaluation alone in patients
without established CAD.
How is it calcium score calculated?
 Agatston score is widely used.
 It is area based.
 Others have used volume and mass
 Coronary calcification is pathognomonic of
atherosclerosis and represents an attempt at
healing.
 Typically pixels with >130 HU (?90HU )are considered
to represent calcification.
 Area of the lesion is multiplied by a coefficient.(1-4).
 Agatston scores of all lesions are summarized to yield
the total Agatston scores per vessel and per patient.
FALLACY
 Does not detect non-calcified atherosclerotic
plaque.
 Cannot accurately assess presence or absence
of CAD.
 Gives a crude estimate of atherosclerotic
burden.
 CC Scores are lower in African American men than in
Caucasian men.
 Interscan reproducibilty is substantially better for high
calcium scores.
 Interscan variability is rather high. So follow up testing is
not recommended.
 Calculate calcium score from CCTA from dual energy in
future.
 Using iterative reconstruction to reduce dose in future.
2
2. Regarding contrast protocol for
performing pulmonary vein imaging
which one of the following is true.
 A. Identical to coronary CTA.
 B. Requires higher contrast flow rates.
 C. Bolus tracker should be placed at level of left
atrium.
 D. One should not consider using prospectively
ECG triggered CT.
C. Bolus tracker should be placed
at level of left atrium.
TECHNIQUE
 Prospective or retrospective ECG gated study .
 ROI is left atrium.
 No beta blocker needed as we are not
assessing coronary arteries.
 Patient frequently in A.fib.
ASSESSMENT
 LA size.
 Anatomy of pulmonary veins- numbers, variations.
 Ostial size is measured in Mid diastole to guide catheter
sizes for EP ablation. Measured 1 cm from ostia in
orthogonal reconstructed view.
 LAA thrombus vs mixing artefact is differentiated by
repeat CT 45-60 seconds later.
 Relationship to esophagus- VR image provided.
VARIATIONS
 LA Area – 11- 33 cm2.
 Normal 2 left and 2 right PV.
 Variations- 1 (common) left and 2 right PV.
-2 left and 3 right PV ( separate
ostia for middle lobe.)
COMPLICATIONS
 PV Stenosis.
 Esophageal perforation.
 Cardiac tamponade.
 Throbo-embolism.
 Phrenic nerve injury.
3
3. All the following are coronary veins
except
A. Small cardiac vein.
B. Middle cardiac vein.
C. Large cardiac vein.
D. Great cardiac vein.
C. Large cardiac vein.
CORONARY VEINS
TECHNIQUE
Images are obtained 5-10 sec
delay after ROI on aorta to
allow for coronary venous
return.
IMPORTANCE
 To look for variations and assist in EP
procedures like BIVICD Placement.
 Also not to falsely confuse a vein as a patent
coronary artery.
4
What is the diagnosis?
4. Question.
What is the diagnosis?
A. Coronary aneurysm.
B. Coronary ectasia.
C. Coronary fistula.
D. Coronary dissection
B. Coronary ectasia.
5
5. What is the diagnosis?
A. Hyper trophic cardiomyopathy.
B. Non Compaction syndrome.
C. Arrhythmogenic RV dysplasia.
D. Ebsteins anomaly.
C. Arrhythmogenic RV dysplasia.
•Right ventricular dysfunction
• Severe dilatation and reduction of RV ejection
fraction with little or no LV impairment
• Localized RV aneurysms
• Severe segmental dilatation of the RV
•Tissue characterization
• Fibrofatty replacement of myocardium on
endomyocardial biopsy
•Conduction abnormalities
• Epsilon waves in V1 - V3.
• Localized prolongation (>110 ms) of QRS in V1 - V3
•Family history
Major Criteria
•Right ventricular dysfunction
• Mild global RV dilatation and/or reduced ejection
fraction with normal LV.
• Mild segmental dilatation of the RV
• Regional RV hypokinesis
•Tissue characterization
•Conduction abnormalities
• Inverted T waves in V2 and V3 in an individual over 12
years old, in the absence of a right bundle branch
block (RBBB)
• Late potentials on signal averaged EKG.
• Ventricular tachycardia with a left bundle branch
block (LBBB) morphology
• Frequent PVCs (> 1000 PVCs / 24 hours)
•Family history
• Family history of sudden cardiac death before age 35
Minor Criteria
ARVD diagnostic criteria
 There is no pathognomonic feature of ARVD.
The diagnosis of ARVD is based on a
combination of major and minor criteria.
 To make a diagnosis of ARVD requires either
2 major criteria or
 1 major and 2 minor criteria or
 4 minor criteria.
ARVD
 Genetic Cardiomyopathy.
 Fibro fatty replacement of RV myocardium.
 LBBB
 Autosomal dominant with incomplete
penetrance and autosomal recessive
inheritance.
 Positive family history in 30-50%.
6
6.Visibility of stent lumen depends on all
of the following except
A. Scanner technology.
B. Stent size.
C. Stent length.
D. Stent lumen.
C. Stent length.
 RCA STENT SHARP FILTER  RCA STENT MEDIUM FILTER
7
7.What is the diagnosis?
A. Transposition of great vessels.
B. Truncus arteriosus.
C. Coarctation of aorta.
D. Tetralogy of Fallot.
D. Tetralogy of Fallot with ASD
and Cor triatrium.
8.
8.What syndrome does this
patient have?
A. Downs syndrome.
B. Tuberous sclerosis.
C. Von Hippel landau disease.
D. Turners syndrome.
B. Tuberous sclerosis.
9
9.Patient with history of recent stroke.
A. Atrial thrombus.
B. LV thrombus.
C. Aortic dissection.
D. Pulmonary embolism and ASD.
ANSWER
B. LV THROMBUS


10
10.What is the diagnosis?
A. Left atrial thrombus.
B. Left atrial myxoma.
C. left atrial lipoma.
D. Atrial septal aneurysm.
B. Left atrial myxoma.
11
11. Using bolus tracking which is ideal
attenuation threshold for performing
coronary CTA.
 LOCATION THRESHOLD
A. Descending Aorta 400 HU
B. Ascending Aorta 300 HU
C. Descending Aorta 350 HU
D. Ascending Aorta 150 HU
D. Ascending Aorta 150 HU
12
12. Second most common cause of
sudden death?
A. Hypertrophic cardiomyopathy.
B. Anomalous origin and course of
coronary arteries.
C. Arrhythmia.
D. Coronary dissection.
B. Anomalous origin and
course of coronary arteries.
13
13.“Triple rule out”- simultaneous
opacification of coronaries, aorta and
pulmonary artery?
A. Faster contrast injection rate.
B. Larger contrast volume.
C. Higher tube current.
D. Thicker slice collimation.
B. Larger contrast volume.
14
14. Patient has had CABG, LIMA to LAD and SVG to OM. All the
following are true regarding coronary CTA except
A. CCTA has poor accuracy in assessing disease within
bypass grafts.
B. Radiation exposure is higher than in a CTA
evaluating native vessels.
C. His native coronaries will likely be heavily calcified
which may potentially limit diagnostic accuracy.
D. Routine surveillance of bypass graft patency in
asymptomatic is not considered appropriate.
A. CCTA has poor accuracy in
assessing disease within bypass
grafts.
Curved MPR Straight MPR
15
15. What does this 87 year female
have?
A. Coronary artery fistula.
B. Coronary artery dissection.
C. Coronary artery aneurysm.
D. Coronary artery ectasia.
A. Coronary artery fistula.
16
16. Name the artery arising from circumflex
coronary artery. Study performed prior to
RF ablation.
A. S shaped SA nodal artery.
B. Obtuse marginal artery.
C. AV nodal artery.
D. Acute marginal artery.
17
17. Name the anomalous artery.
A. RCA.
B. LAD.
C. Circumflex coronary artery.
D. SA nodal artery.
ANSWER
C. Circumflex of RCA
18
18. Name the anomalous artery.
A. RCA.
B. LAD.
C. Circumflex coronary artery.
D. SA nodal artery.
ANSWER
 C. Circumflex artery of right cusp separate ostia.
19
19. What is a common pitch for a typical coronary
CT angiogram using retrospectively ECG-gated 64 –
slice CT.
A. 0.1
B. 0.2
C.1.0
D. 2.0
B. 0.2
20
20. What surgery did this patient have?
A. ASD closure device.
B. Mitral valve replacement.
C. LA appendage clip.
D. Tricuspid valve replacement.
A. Amplatz ASD occlusion device.
Thanks to
 Dr. William Bates MD.
 Dr. Benett Greenspan MD.
 Dr. Gyanendra Sharma MD.

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Coronary CTA

  • 1. Coronary CTA. August 23, 2014. POOL SOCIETY WEEKEND JAYANTH H KESHAVAMURTHY, M.D. ASSISTANT PROFESSOR OF RADIOLOGY GEORGIA REGENTS UNIVERSITY.
  • 2. 1. Question  An overweight man had CAC SCORE OF 500 last year. He has made significant life style changes since that time. He is now requesting a reevalauation of his cardiovascular risk. What would you recommend?  A. Coronary CTA with CAC score.  B. Coronary CTA without CAC score.  C. CAC score only.  D. Neither Coronary CTA nor CAC score.
  • 4.
  • 5.
  • 6. TECHNIQUE  Prospective ECG triggered.  120kVP  Slice Collimation 2.5 -3mm.  Medium sharp reconstruction kernel without edge enhancement- provides moderate image noise.
  • 7. TECHNIQUE  Z axis from carina to base of heart.  FOV is 250 mm.
  • 8. INDICATIONS  Risk stratification in asymptomatic individual.  With intermediate Framingham Risk Score.
  • 9. USEFULNESS  Incremental prognostic information.  Independent risk assessment over Framingham risk evaluation alone in patients without established CAD.
  • 10. How is it calcium score calculated?  Agatston score is widely used.  It is area based.  Others have used volume and mass
  • 11.  Coronary calcification is pathognomonic of atherosclerosis and represents an attempt at healing.
  • 12.  Typically pixels with >130 HU (?90HU )are considered to represent calcification.  Area of the lesion is multiplied by a coefficient.(1-4).  Agatston scores of all lesions are summarized to yield the total Agatston scores per vessel and per patient.
  • 13.
  • 14. FALLACY  Does not detect non-calcified atherosclerotic plaque.  Cannot accurately assess presence or absence of CAD.  Gives a crude estimate of atherosclerotic burden.
  • 15.  CC Scores are lower in African American men than in Caucasian men.  Interscan reproducibilty is substantially better for high calcium scores.  Interscan variability is rather high. So follow up testing is not recommended.
  • 16.  Calculate calcium score from CCTA from dual energy in future.  Using iterative reconstruction to reduce dose in future.
  • 17. 2
  • 18. 2. Regarding contrast protocol for performing pulmonary vein imaging which one of the following is true.  A. Identical to coronary CTA.  B. Requires higher contrast flow rates.  C. Bolus tracker should be placed at level of left atrium.  D. One should not consider using prospectively ECG triggered CT.
  • 19. C. Bolus tracker should be placed at level of left atrium.
  • 20. TECHNIQUE  Prospective or retrospective ECG gated study .  ROI is left atrium.  No beta blocker needed as we are not assessing coronary arteries.  Patient frequently in A.fib.
  • 21. ASSESSMENT  LA size.  Anatomy of pulmonary veins- numbers, variations.  Ostial size is measured in Mid diastole to guide catheter sizes for EP ablation. Measured 1 cm from ostia in orthogonal reconstructed view.  LAA thrombus vs mixing artefact is differentiated by repeat CT 45-60 seconds later.  Relationship to esophagus- VR image provided.
  • 22. VARIATIONS  LA Area – 11- 33 cm2.  Normal 2 left and 2 right PV.  Variations- 1 (common) left and 2 right PV. -2 left and 3 right PV ( separate ostia for middle lobe.)
  • 23. COMPLICATIONS  PV Stenosis.  Esophageal perforation.  Cardiac tamponade.  Throbo-embolism.  Phrenic nerve injury.
  • 24. 3
  • 25. 3. All the following are coronary veins except A. Small cardiac vein. B. Middle cardiac vein. C. Large cardiac vein. D. Great cardiac vein.
  • 28.
  • 29. TECHNIQUE Images are obtained 5-10 sec delay after ROI on aorta to allow for coronary venous return.
  • 30. IMPORTANCE  To look for variations and assist in EP procedures like BIVICD Placement.  Also not to falsely confuse a vein as a patent coronary artery.
  • 31.
  • 32.
  • 33. 4
  • 34. What is the diagnosis?
  • 35. 4. Question. What is the diagnosis? A. Coronary aneurysm. B. Coronary ectasia. C. Coronary fistula. D. Coronary dissection
  • 37.
  • 38. 5
  • 39. 5. What is the diagnosis? A. Hyper trophic cardiomyopathy. B. Non Compaction syndrome. C. Arrhythmogenic RV dysplasia. D. Ebsteins anomaly.
  • 40.
  • 42.
  • 43. •Right ventricular dysfunction • Severe dilatation and reduction of RV ejection fraction with little or no LV impairment • Localized RV aneurysms • Severe segmental dilatation of the RV •Tissue characterization • Fibrofatty replacement of myocardium on endomyocardial biopsy •Conduction abnormalities • Epsilon waves in V1 - V3. • Localized prolongation (>110 ms) of QRS in V1 - V3 •Family history Major Criteria
  • 44. •Right ventricular dysfunction • Mild global RV dilatation and/or reduced ejection fraction with normal LV. • Mild segmental dilatation of the RV • Regional RV hypokinesis •Tissue characterization •Conduction abnormalities • Inverted T waves in V2 and V3 in an individual over 12 years old, in the absence of a right bundle branch block (RBBB) • Late potentials on signal averaged EKG. • Ventricular tachycardia with a left bundle branch block (LBBB) morphology • Frequent PVCs (> 1000 PVCs / 24 hours) •Family history • Family history of sudden cardiac death before age 35 Minor Criteria
  • 45. ARVD diagnostic criteria  There is no pathognomonic feature of ARVD. The diagnosis of ARVD is based on a combination of major and minor criteria.  To make a diagnosis of ARVD requires either 2 major criteria or  1 major and 2 minor criteria or  4 minor criteria.
  • 46. ARVD  Genetic Cardiomyopathy.  Fibro fatty replacement of RV myocardium.  LBBB  Autosomal dominant with incomplete penetrance and autosomal recessive inheritance.  Positive family history in 30-50%.
  • 47. 6
  • 48. 6.Visibility of stent lumen depends on all of the following except A. Scanner technology. B. Stent size. C. Stent length. D. Stent lumen.
  • 50.  RCA STENT SHARP FILTER  RCA STENT MEDIUM FILTER
  • 51.
  • 52. 7
  • 53. 7.What is the diagnosis? A. Transposition of great vessels. B. Truncus arteriosus. C. Coarctation of aorta. D. Tetralogy of Fallot.
  • 54.
  • 55. D. Tetralogy of Fallot with ASD and Cor triatrium.
  • 56.
  • 57. 8.
  • 58. 8.What syndrome does this patient have? A. Downs syndrome. B. Tuberous sclerosis. C. Von Hippel landau disease. D. Turners syndrome.
  • 59.
  • 61.
  • 62.
  • 63.
  • 64.
  • 65.
  • 66.
  • 67. 9
  • 68. 9.Patient with history of recent stroke. A. Atrial thrombus. B. LV thrombus. C. Aortic dissection. D. Pulmonary embolism and ASD.
  • 69.
  • 71.
  • 73.
  • 74. 10
  • 75. 10.What is the diagnosis? A. Left atrial thrombus. B. Left atrial myxoma. C. left atrial lipoma. D. Atrial septal aneurysm.
  • 76.
  • 77. B. Left atrial myxoma.
  • 78.
  • 79.
  • 80.
  • 81.
  • 82. 11
  • 83. 11. Using bolus tracking which is ideal attenuation threshold for performing coronary CTA.  LOCATION THRESHOLD A. Descending Aorta 400 HU B. Ascending Aorta 300 HU C. Descending Aorta 350 HU D. Ascending Aorta 150 HU
  • 85.
  • 86. 12
  • 87. 12. Second most common cause of sudden death? A. Hypertrophic cardiomyopathy. B. Anomalous origin and course of coronary arteries. C. Arrhythmia. D. Coronary dissection.
  • 88. B. Anomalous origin and course of coronary arteries.
  • 89.
  • 90.
  • 91.
  • 92. 13
  • 93. 13.“Triple rule out”- simultaneous opacification of coronaries, aorta and pulmonary artery? A. Faster contrast injection rate. B. Larger contrast volume. C. Higher tube current. D. Thicker slice collimation.
  • 95.
  • 96.
  • 97.
  • 98. 14
  • 99. 14. Patient has had CABG, LIMA to LAD and SVG to OM. All the following are true regarding coronary CTA except A. CCTA has poor accuracy in assessing disease within bypass grafts. B. Radiation exposure is higher than in a CTA evaluating native vessels. C. His native coronaries will likely be heavily calcified which may potentially limit diagnostic accuracy. D. Routine surveillance of bypass graft patency in asymptomatic is not considered appropriate.
  • 100. A. CCTA has poor accuracy in assessing disease within bypass grafts.
  • 101.
  • 102.
  • 104.
  • 105.
  • 106. 15
  • 107. 15. What does this 87 year female have? A. Coronary artery fistula. B. Coronary artery dissection. C. Coronary artery aneurysm. D. Coronary artery ectasia.
  • 108.
  • 110.
  • 111. 16
  • 112. 16. Name the artery arising from circumflex coronary artery. Study performed prior to RF ablation. A. S shaped SA nodal artery. B. Obtuse marginal artery. C. AV nodal artery. D. Acute marginal artery.
  • 113.
  • 114.
  • 115. 17
  • 116. 17. Name the anomalous artery. A. RCA. B. LAD. C. Circumflex coronary artery. D. SA nodal artery.
  • 117.
  • 119.
  • 120. 18
  • 121. 18. Name the anomalous artery. A. RCA. B. LAD. C. Circumflex coronary artery. D. SA nodal artery.
  • 122.
  • 123. ANSWER  C. Circumflex artery of right cusp separate ostia.
  • 124. 19
  • 125. 19. What is a common pitch for a typical coronary CT angiogram using retrospectively ECG-gated 64 – slice CT. A. 0.1 B. 0.2 C.1.0 D. 2.0
  • 126. B. 0.2
  • 127. 20
  • 128. 20. What surgery did this patient have? A. ASD closure device. B. Mitral valve replacement. C. LA appendage clip. D. Tricuspid valve replacement.
  • 129.
  • 130. A. Amplatz ASD occlusion device.
  • 131.
  • 132. Thanks to  Dr. William Bates MD.  Dr. Benett Greenspan MD.  Dr. Gyanendra Sharma MD.