2. Knowing nothing is not a matter of
shame.
uval Noah Harari is an Israeli author, public
intellectual, historian and professor in the
Department of History at the Hebrew University of
Jerusalem.
4. Learning objectives
• Define oral Mucosa.
• Classify oral mucous membrane
• Explain the components of oral mucosa
5. Oral mucosa
The term mucous membrane is used to describe the
moist lining of the gastrointestinal tract, nasal passages,
and other body cavities that communicate with the
exterior. In the oral cavity, this lining is referred to as the
oral mucous membrane, or oral mucosa
9. Lamina propria
Fibers and Ground Substance
• Collagen---Type I and III, Type V in the inflammed
tissue
• Elastin (flexible lining mucosa) that together with
fibronectin embed in the ground substance.
• Ground Substance: amorphous at the molecular level
• Proteoglycans: In the oral mucosa the proteoglycans
are represented by hyaluronan, heparan sulfate,
versican, decorin, biglycan, and syndecan.
• Glycoproteins: have a polypeptide chain to which only
a few simple hexoses are attached.
• Cells: The lamina propria contains several different
cells: fibroblasts, macrophages, mast cells, and
inflammatory cells.
10. Keratinized OM and NON keratinized OM.
• The classification of oral mucosa into keratinized and non-keratinized
is primarily based on the presence or absence of keratinized
epithelial cells in the tissue. Keratinization is a natural process that
occurs in the epithelial cells of the skin and certain mucosal surfaces
• ,
11. Keratinized oral mucousa
Connective Tissue Papila
Epithelial Rete Ridges’
Sub mucousa
2/3
Keratohyaline granule
;linking of
tonofailments to
form tonofibrils
Lamellate granules;fuse with CM
and release lipds in ICS OR
act as a barriers .
No nucleus ,densly packed
tonofibrills ,keratine protein ,
1
2
3
4
Same in both keratinize
OM and non keratinized
OM ALMOST .
2
1`
12. ½ of its number
and 2/3 its
thickness of both
kert OM and non
kert OM
The cells produce
keratohyalin granules
(discussed later), which
release the precursor of
the intermediate
filament protein filaggrin
protective layer called the
cornified cell envelope, which
consists essentially of keratins
embedded in an insoluble
amalgam of proteins surrounded
by lipids
18. Secretion:
• Saliva:
• major and minor salivary
glands
• Sebaceous glands commonly
are present in the oral
mucosa, but their secretions
are probably insignificant
Mucous membrane is used to describe the moist lining of GIT, nasal passages and other cavities of body that communicate with the exterior
In oral cavity this lining is Oral mucous membrane or oral mucosa
At the lips the oral mucosa is continuous with the skin; at the pharynx the oral mucosa is continuous with the mucosa lining the rest of the gu
Located between skin and GIT and shows some properties of each
In the skin these two tissues are known as the epidermis and dermis
OM separates and protects deeper tissues and organs from the environment of oral cavity
The normal activities of seizing food and biting and chewing expose the oral soft tissues to mechanical forces
The oral mucosa shows a number of adaptations of the epithelium and the connective tissue to withstand these insults.
The epithelium of the oral mucosa acts as the major barrier to these threats.
The major secretion associated with the oral mucosa is saliva.
Salivary secretion is important for moistening the oral cavity comes from
The major salivary glands are situated distant from the mucosa, and their secretions pass through the mucosa via long ducts; however, many minor salivary glands are associated with the oral mucosa
Sensory function is important because it provide considerable information about events in oral cavity.
Reflexes such as swallowing, gagging, retching, and salivating also are initiated by receptors in the oral mucosa.
In some animals (such as the dog), considerable body heat is dissipated through the oral mucosa by panting