SlideShare ist ein Scribd-Unternehmen logo
1 von 46
Downloaden Sie, um offline zu lesen
Platelet Rich Plasma
Art & science
Islam Kassem,BDS,MSc,FDS RCS
Consultant oral & maxillofacial Surgeon
ikassem@dr.com
Angle Face Left
New technology of injection
your own blood to get a
Youthful Look .
.
ikassem@dr.com
Why Are Celebrities
Injecting Their Faces
With Blood?
ikassem@dr.com
ikassem@dr.com
Platelet?
 Anuclear piece of cytoplasm
 Include hemostasis,
α-granule,lysosomal granule,
dense granules
ikassem@dr.com
 At least 7 different growth
factors that stimulate bone &
soft tissue healing
 PDGF aa,bb,ab
 TGF b1,b2
 VEGF
 EGF
ikassem@dr.com
Days of operation
ikassem@dr.com
7 days later
 PLT exhausted after 7 days
 Macrophage by low oxygen
tension, acidity, lactate
concentration
 Secrete same growth factors
 Activated until it is down
regulated by the restoration of
normal oxygen tension
ikassem@dr.com
Day 3rd
ikassem@dr.com
17days
 Graft is completely permeated
by new capillaries
 Initial osteoid formation
 Osteoclast resorb osteoid and
BMP released
 New bone formation and
maturation
ikassem@dr.com
Days 14
ikassem@dr.com
The mechanism of growth factor
effects on cells
Inactive state
ikassem@dr.com
Activation
activation
ikassem@dr.com
Clinical effects of PRP on bone
regeneration
Platelet
RBC
Normal blood PRP
ikassem@dr.com
Trabecular areaNative mandible Autogenous BG
ikassem@dr.com
Clinical effects of PRP on soft tissue
healing
 Split thickness skin graft donor site healing
ikassem@dr.com
6 days
Thrombin side
: 5% epithelization
95% granulation
tissue
PRP side
; 95% epithelization
5% granulation
tissue
ikassem@dr.com
6 months
Thrombin side
: scarring
hypo and
hyper-
pigmentation
area
PRP side
;less scarring
Much less
pigmentation
change
ikassem@dr.com
Patient discomfort
 Patient
discomfort
decrease
ikassem@dr.com
Epithelization
ikassem@dr.com
6days
↔
↔
ikassem@dr.com
1 months
ikassem@dr.com
Contraindications
 Pre-existing coagulation defect
: thrombocytopenia, hypofibrinogenia…
 Hypersensitivity to bovine thrombin
ikassem@dr.com
Clinical steps
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
Clinical
application
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
Ridge preservation
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com
ikassem@dr.com

Weitere ähnliche Inhalte

Was ist angesagt?

PRP Platelet Rich Plasma for Hair Regrowth by Dr. Alan Bauman
PRP Platelet Rich Plasma for Hair Regrowth by Dr. Alan BaumanPRP Platelet Rich Plasma for Hair Regrowth by Dr. Alan Bauman
PRP Platelet Rich Plasma for Hair Regrowth by Dr. Alan Bauman
Bauman Medical Group, P.A.
 

Was ist angesagt? (20)

PRP Platelet Rich Plasma for Hair Regrowth by Dr. Alan Bauman
PRP Platelet Rich Plasma for Hair Regrowth by Dr. Alan BaumanPRP Platelet Rich Plasma for Hair Regrowth by Dr. Alan Bauman
PRP Platelet Rich Plasma for Hair Regrowth by Dr. Alan Bauman
 
PRP Update: From basic science to clinical application
PRP Update: From basic science to clinical applicationPRP Update: From basic science to clinical application
PRP Update: From basic science to clinical application
 
PRP Treatment For Face
PRP Treatment For FacePRP Treatment For Face
PRP Treatment For Face
 
PRP Injections
PRP InjectionsPRP Injections
PRP Injections
 
Face lift without surgery
Face lift without surgeryFace lift without surgery
Face lift without surgery
 
Intraarticular Platelet-Rich Plasma
Intraarticular Platelet-Rich Plasma Intraarticular Platelet-Rich Plasma
Intraarticular Platelet-Rich Plasma
 
PRP
PRPPRP
PRP
 
Prp for hair regrowth
Prp for hair regrowthPrp for hair regrowth
Prp for hair regrowth
 
PRP Biologics 2
PRP Biologics 2PRP Biologics 2
PRP Biologics 2
 
Cog | Face Lift Surgery
Cog | Face Lift SurgeryCog | Face Lift Surgery
Cog | Face Lift Surgery
 
PRP IN EGYPT
PRP IN EGYPTPRP IN EGYPT
PRP IN EGYPT
 
Botox® cosmetic show
Botox® cosmetic showBotox® cosmetic show
Botox® cosmetic show
 
Threadlift pp anti aging
Threadlift pp anti agingThreadlift pp anti aging
Threadlift pp anti aging
 
Prp presentation
Prp presentationPrp presentation
Prp presentation
 
Management of complications of dermal fillers implant
Management of complications of dermal fillers implantManagement of complications of dermal fillers implant
Management of complications of dermal fillers implant
 
Mesobotox: a New Technique for Aesthetic Treatments
Mesobotox: a New Technique for Aesthetic TreatmentsMesobotox: a New Technique for Aesthetic Treatments
Mesobotox: a New Technique for Aesthetic Treatments
 
Prp hair-loss-treatment
Prp hair-loss-treatmentPrp hair-loss-treatment
Prp hair-loss-treatment
 
Regenerative Medicine
Regenerative Medicine Regenerative Medicine
Regenerative Medicine
 
HIFU- DR LALIT RAJPAL
HIFU- DR LALIT RAJPALHIFU- DR LALIT RAJPAL
HIFU- DR LALIT RAJPAL
 
Platelet rich plasma
Platelet rich plasma Platelet rich plasma
Platelet rich plasma
 

Andere mochten auch (8)

Dr Michael Toffler: 10-Year Experience Using L-PRF in Ridge and Sinus Augment...
Dr Michael Toffler: 10-Year Experience Using L-PRF in Ridge and Sinus Augment...Dr Michael Toffler: 10-Year Experience Using L-PRF in Ridge and Sinus Augment...
Dr Michael Toffler: 10-Year Experience Using L-PRF in Ridge and Sinus Augment...
 
Using Platelet Rich Plasma for Orthopedic Conditions
Using Platelet Rich Plasma for Orthopedic ConditionsUsing Platelet Rich Plasma for Orthopedic Conditions
Using Platelet Rich Plasma for Orthopedic Conditions
 
Platelet rich plasma
Platelet rich plasmaPlatelet rich plasma
Platelet rich plasma
 
Medical problem 3 4
Medical problem 3 4Medical problem 3 4
Medical problem 3 4
 
Platelet Rich Plasma in Orthopaedics
Platelet Rich Plasma in OrthopaedicsPlatelet Rich Plasma in Orthopaedics
Platelet Rich Plasma in Orthopaedics
 
Platelet Rich Plasma Review
Platelet Rich Plasma ReviewPlatelet Rich Plasma Review
Platelet Rich Plasma Review
 
Platelet rich fibrin
Platelet rich fibrinPlatelet rich fibrin
Platelet rich fibrin
 
Platelet rich fibrin
Platelet rich fibrinPlatelet rich fibrin
Platelet rich fibrin
 

Mehr von islam kassem (20)

MRONJ
MRONJMRONJ
MRONJ
 
Osteomyelitis of the jaws
Osteomyelitis of the jawsOsteomyelitis of the jaws
Osteomyelitis of the jaws
 
Mronj position paper
Mronj position paperMronj position paper
Mronj position paper
 
Lip & chin
Lip & chinLip & chin
Lip & chin
 
Smile line using botox
Smile line using botox Smile line using botox
Smile line using botox
 
Facial esthetics kuwait
Facial esthetics kuwaitFacial esthetics kuwait
Facial esthetics kuwait
 
Introduction
IntroductionIntroduction
Introduction
 
Bahrain june laser workshop
Bahrain june laser workshopBahrain june laser workshop
Bahrain june laser workshop
 
Medical problems 4 4
Medical problems 4 4Medical problems 4 4
Medical problems 4 4
 
Medical problems 2 4
Medical problems 2 4Medical problems 2 4
Medical problems 2 4
 
Medical problems 1 4
Medical problems 1 4Medical problems 1 4
Medical problems 1 4
 
Rad interpretation
Rad interpretationRad interpretation
Rad interpretation
 
Pdl
PdlPdl
Pdl
 
Odontogenic tumours
Odontogenic tumoursOdontogenic tumours
Odontogenic tumours
 
Developmental abnormalities
Developmental abnormalitiesDevelopmental abnormalities
Developmental abnormalities
 
Dental carries
Dental carriesDental carries
Dental carries
 
Cyst
CystCyst
Cyst
 
Panoramic x ray
Panoramic x rayPanoramic x ray
Panoramic x ray
 
Localization tech
Localization techLocalization tech
Localization tech
 
Impactions
ImpactionsImpactions
Impactions
 

Kürzlich hochgeladen

Jaipur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Jaipur No💰...
Jaipur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Jaipur No💰...Jaipur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Jaipur No💰...
Jaipur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Jaipur No💰...
Sheetaleventcompany
 
Control of Local Blood Flow: acute and chronic
Control of Local Blood Flow: acute and chronicControl of Local Blood Flow: acute and chronic
Control of Local Blood Flow: acute and chronic
MedicoseAcademics
 
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan 087776558899
 
Jual Obat Aborsi Di Dubai UAE Wa 0838-4800-7379 Obat Penggugur Kandungan Cytotec
Jual Obat Aborsi Di Dubai UAE Wa 0838-4800-7379 Obat Penggugur Kandungan CytotecJual Obat Aborsi Di Dubai UAE Wa 0838-4800-7379 Obat Penggugur Kandungan Cytotec
Jual Obat Aborsi Di Dubai UAE Wa 0838-4800-7379 Obat Penggugur Kandungan Cytotec
jualobat34
 
Premium Call Girls Nagpur {9xx000xx09} ❤️VVIP POOJA Call Girls in Nagpur Maha...
Premium Call Girls Nagpur {9xx000xx09} ❤️VVIP POOJA Call Girls in Nagpur Maha...Premium Call Girls Nagpur {9xx000xx09} ❤️VVIP POOJA Call Girls in Nagpur Maha...
Premium Call Girls Nagpur {9xx000xx09} ❤️VVIP POOJA Call Girls in Nagpur Maha...
Sheetaleventcompany
 
👉Chandigarh Call Girl Service📲Niamh 8868886958 📲Book 24hours Now📲👉Sexy Call G...
👉Chandigarh Call Girl Service📲Niamh 8868886958 📲Book 24hours Now📲👉Sexy Call G...👉Chandigarh Call Girl Service📲Niamh 8868886958 📲Book 24hours Now📲👉Sexy Call G...
👉Chandigarh Call Girl Service📲Niamh 8868886958 📲Book 24hours Now📲👉Sexy Call G...
Sheetaleventcompany
 
💚Chandigarh Call Girls 💯Riya 📲🔝8868886958🔝Call Girls In Chandigarh No💰Advance...
💚Chandigarh Call Girls 💯Riya 📲🔝8868886958🔝Call Girls In Chandigarh No💰Advance...💚Chandigarh Call Girls 💯Riya 📲🔝8868886958🔝Call Girls In Chandigarh No💰Advance...
💚Chandigarh Call Girls 💯Riya 📲🔝8868886958🔝Call Girls In Chandigarh No💰Advance...
Sheetaleventcompany
 
Nagpur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Nagpur No💰...
Nagpur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Nagpur No💰...Nagpur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Nagpur No💰...
Nagpur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Nagpur No💰...
Sheetaleventcompany
 

Kürzlich hochgeladen (20)

7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta
7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta
7 steps How to prevent Thalassemia : Dr Sharda Jain & Vandana Gupta
 
Most Beautiful Call Girl in Chennai 7427069034 Contact on WhatsApp
Most Beautiful Call Girl in Chennai 7427069034 Contact on WhatsAppMost Beautiful Call Girl in Chennai 7427069034 Contact on WhatsApp
Most Beautiful Call Girl in Chennai 7427069034 Contact on WhatsApp
 
Intramuscular & Intravenous Injection.pptx
Intramuscular & Intravenous Injection.pptxIntramuscular & Intravenous Injection.pptx
Intramuscular & Intravenous Injection.pptx
 
Kolkata Call Girls Shobhabazar 💯Call Us 🔝 8005736733 🔝 💃 Top Class Call Gir...
Kolkata Call Girls Shobhabazar  💯Call Us 🔝 8005736733 🔝 💃  Top Class Call Gir...Kolkata Call Girls Shobhabazar  💯Call Us 🔝 8005736733 🔝 💃  Top Class Call Gir...
Kolkata Call Girls Shobhabazar 💯Call Us 🔝 8005736733 🔝 💃 Top Class Call Gir...
 
VIP Hyderabad Call Girls KPHB 7877925207 ₹5000 To 25K With AC Room 💚😋
VIP Hyderabad Call Girls KPHB 7877925207 ₹5000 To 25K With AC Room 💚😋VIP Hyderabad Call Girls KPHB 7877925207 ₹5000 To 25K With AC Room 💚😋
VIP Hyderabad Call Girls KPHB 7877925207 ₹5000 To 25K With AC Room 💚😋
 
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
 
Jaipur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Jaipur No💰...
Jaipur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Jaipur No💰...Jaipur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Jaipur No💰...
Jaipur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Jaipur No💰...
 
tongue disease lecture Dr Assadawy legacy
tongue disease lecture Dr Assadawy legacytongue disease lecture Dr Assadawy legacy
tongue disease lecture Dr Assadawy legacy
 
Gastric Cancer: Сlinical Implementation of Artificial Intelligence, Synergeti...
Gastric Cancer: Сlinical Implementation of Artificial Intelligence, Synergeti...Gastric Cancer: Сlinical Implementation of Artificial Intelligence, Synergeti...
Gastric Cancer: Сlinical Implementation of Artificial Intelligence, Synergeti...
 
🚺LEELA JOSHI WhatsApp Number +91-9930245274 ✔ Unsatisfied Bhabhi Call Girls T...
🚺LEELA JOSHI WhatsApp Number +91-9930245274 ✔ Unsatisfied Bhabhi Call Girls T...🚺LEELA JOSHI WhatsApp Number +91-9930245274 ✔ Unsatisfied Bhabhi Call Girls T...
🚺LEELA JOSHI WhatsApp Number +91-9930245274 ✔ Unsatisfied Bhabhi Call Girls T...
 
Control of Local Blood Flow: acute and chronic
Control of Local Blood Flow: acute and chronicControl of Local Blood Flow: acute and chronic
Control of Local Blood Flow: acute and chronic
 
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
 
Call 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room Delivery
Call 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room DeliveryCall 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room Delivery
Call 8250092165 Patna Call Girls ₹4.5k Cash Payment With Room Delivery
 
Jual Obat Aborsi Di Dubai UAE Wa 0838-4800-7379 Obat Penggugur Kandungan Cytotec
Jual Obat Aborsi Di Dubai UAE Wa 0838-4800-7379 Obat Penggugur Kandungan CytotecJual Obat Aborsi Di Dubai UAE Wa 0838-4800-7379 Obat Penggugur Kandungan Cytotec
Jual Obat Aborsi Di Dubai UAE Wa 0838-4800-7379 Obat Penggugur Kandungan Cytotec
 
Shazia Iqbal 2024 - Bioorganic Chemistry.pdf
Shazia Iqbal 2024 - Bioorganic Chemistry.pdfShazia Iqbal 2024 - Bioorganic Chemistry.pdf
Shazia Iqbal 2024 - Bioorganic Chemistry.pdf
 
Premium Call Girls Nagpur {9xx000xx09} ❤️VVIP POOJA Call Girls in Nagpur Maha...
Premium Call Girls Nagpur {9xx000xx09} ❤️VVIP POOJA Call Girls in Nagpur Maha...Premium Call Girls Nagpur {9xx000xx09} ❤️VVIP POOJA Call Girls in Nagpur Maha...
Premium Call Girls Nagpur {9xx000xx09} ❤️VVIP POOJA Call Girls in Nagpur Maha...
 
❤️Call Girl Service In Chandigarh☎️9814379184☎️ Call Girl in Chandigarh☎️ Cha...
❤️Call Girl Service In Chandigarh☎️9814379184☎️ Call Girl in Chandigarh☎️ Cha...❤️Call Girl Service In Chandigarh☎️9814379184☎️ Call Girl in Chandigarh☎️ Cha...
❤️Call Girl Service In Chandigarh☎️9814379184☎️ Call Girl in Chandigarh☎️ Cha...
 
👉Chandigarh Call Girl Service📲Niamh 8868886958 📲Book 24hours Now📲👉Sexy Call G...
👉Chandigarh Call Girl Service📲Niamh 8868886958 📲Book 24hours Now📲👉Sexy Call G...👉Chandigarh Call Girl Service📲Niamh 8868886958 📲Book 24hours Now📲👉Sexy Call G...
👉Chandigarh Call Girl Service📲Niamh 8868886958 📲Book 24hours Now📲👉Sexy Call G...
 
💚Chandigarh Call Girls 💯Riya 📲🔝8868886958🔝Call Girls In Chandigarh No💰Advance...
💚Chandigarh Call Girls 💯Riya 📲🔝8868886958🔝Call Girls In Chandigarh No💰Advance...💚Chandigarh Call Girls 💯Riya 📲🔝8868886958🔝Call Girls In Chandigarh No💰Advance...
💚Chandigarh Call Girls 💯Riya 📲🔝8868886958🔝Call Girls In Chandigarh No💰Advance...
 
Nagpur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Nagpur No💰...
Nagpur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Nagpur No💰...Nagpur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Nagpur No💰...
Nagpur Call Girl Service 📞9xx000xx09📞Just Call Divya📲 Call Girl In Nagpur No💰...
 

PRP Art & science