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Iris Thiele Isip Tan MD, MSc

Professor 3, UP College of Medicine

Chief, UP Medical Informatics Unit
CLINICAL INFORMATICS
What?
Why?
How?
is clinical
informatics
learn
informatics
can
informatics
improve
healthcare
It’s not just computers!
Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938.
Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938.
Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938.
Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938.
“

Clinical informaticians transform health care by
analyzing, designing, implementing, and
evaluating information and communication
systems that enhance individual and
population health outcomes, improve
patient care, and strengthen the
clinician-patient relationship.
”
– Gardner RM et al JAMIA 2009;16:153-157
Gardner RM et al JAMIA 2009;16:153-157
Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938.
MSc Health Informatics (UP Manila)
Medical
Informatics
track (UPCM) Bioinformatics
track (CAS)
What?
Why?
How?
is clinical
informatics
learn
informatics
can
informatics
improve
healthcare
“We are drowning in information
and starving for knowledge.”
Rutherford D. Rogers
http://www.infogineering.net/data-information-knowledge.htm
Building a Health
Information Infrastructure
Why electronic health records? by
InfowayInfoRoute https://youtu.be/Lo_3qOejQzI
National eHealth Vision Philippines
Photo by Doun, https://flic.kr/p/b5WFRK
By 2020, eHealth will enable widespread access to health care services,
health information and securely share and exchange patient information in
support of safer, quality health care, more equitable and responsive health
system for all the Filipino people by transforming the way information is used to
plan, manage, deliver and monitor health services.
IT-enabled
health services
By 2020
Philippine Health Information Exchange
(PHIE) implementation
EMR certification
IT in all public
health facilities
National eHealth Vision
Rule VIII. Governance & Accountablity
Sec. 36

All health service providers and insurers are required to
maintain a health information system on enterprise
resource planning, human resource information system,
electronic health records and electronic prescription
log consistent with standards set by the DOH and
Philhealth in consultation with the DICT and the NPC …
RA 11223
Universal Healthcare Act
RA 11223
Universal Healthcare Act
Rule VIII. Governance & Accountablity
Sec. 36

PhilHealth shall use its contracts to incentivize the
incorporation of HIS, automation of clinical
information, improvement of data quality, integration
and use of telemedicine, and participation in regional
or national health information networks.
Art 4. Sec 3.3 Program Educational Objectives
With additional training, graduates of the MD program
may pursue any of the following careers to include:

• General medical practitioner

• Clinical specialist

• Researcher/Medical Scientist/Innovator
• Health professions teacher

• Health administrator

• Health information manager
• Health economist

• Health policy maker
CHED Memorandum Order 18
Series of 2016
Art 5. Sec 6.3 Minimum Curricular Content
The minimum curricular content regardless of the
curriculum design shall include the following: 

• Research, evidence-based medicine and medical
informatics
CHED Memorandum Order 18
Series of 2016
What?
Why?
How?
is clinical
informatics
learn
informatics
can
informatics
improve
healthcare
Patient Safety &
Clinical Informatics
Assemble a
complete picture of
the patient, including
tracking the course
of disease and the
effect of therapies
over time
Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407
Patient Safety &
Clinical Informatics
Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407
Assembling the relevant
medical knowledge
REAL-WORLD DATA: Information on health care that
is derived from multiple sources outside typical clinical
research settings, including electronic health records
(EHRs), claims and billing data, product and disease
registries, and data gathered through personal devices
and health applications.
NEJM 2016;375(23):2293-7
Patient Safety &
Clinical Informatics
Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407
Assembling the relevant
medical knowledge
Enhance adherence of
clinical practice to tenets of
EBM: prompting adherence to
protocols/guidelines via
computerized order entry
Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407
Patient Safety &
Clinical Informatics
Applying timely and
accurate knowledge of
medicine to the patient’s
current condition

Clinical Decision Support
Gather & make associations between pieces of information
that may be missed because of sheer volume of data
Bates et al JAMIA 2003;10:523-530
Buch et al. Diabet Med 2018;35:495-7.
Clinical guidelines will be
delivered through apps
rather than static documents.
Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407
Patient Safety & Clinical Informatics
Information systems to prevent, intercept and
ameliorate harm
Preventing mistakes
https://mysugr.com/mysugr-bolus-calculator/
Insulin on board
Blood glucose
Carbs
Previous injections
Carbs/insulin ratio
Insulin correction
factor
Blood glucose
target
MySugr Bolus
Calculator
https://www.uni-trier.de/index.php?id=44502&L=2
CASE-BASED REASONING
Problem-solving paradigm in
artificial intelligence
Similar problems tend to
have similar solutions
Case base: collection of
memorized chunks of
experience (cases)
Adaptive systems: new problem
solving experience is retained and
outdated experience is removed
Brown D et al. Temporal case-based reasoning for type 1 diabetes mellitus bolus
insulin decision support. Artificial Intelligence in Medicine 2018;85:28-42.
Focus on helping patient directly
(instead of aiding the clinician)
RETAINS all
successful cases
Derives bolus
suggestion from
similar cases
Brown D et al. Temporal case-based reasoning for type 1 diabetes mellitus bolus insulin
decision support. Artificial Intelligence in Medicine 2018;85:28-42.
CBR method can be
adopted by insulin
pumps, blood glucose
monitors, PCs and as
a web service
CBR service in the cloud opens possibility
of case sharing between subjects
Brown D et al. Temporal case-based reasoning for type 1 diabetes mellitus bolus insulin
decision support. Artificial Intelligence in Medicine 2018;85:28-42.
Patient Safety &
Clinical Informatics
Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407
Assembling the relevant
medical knowledge
Enhance adherence of
clinical practice to tenets of
EBM: prompting adherence to
protocols/guidelines via
computerized order entry
Clinical data mining to
increase understanding of
disease
Can we predict individuals’ medical diagnoses
from language posted on social media?
Merchant RA et al. doi.org/10.1371/journal.pone.0215476
Can we identify specific markers of
disease from social media posts?
Merchant RA et al. doi.org/10.1371/journal.pone.0215476
SOCIAL MEDIA + EMR
Merchant RA et al. doi.org/10.1371/journal.pone.0215476
Facebook alone
Demographics alone
Demographics and Facebook
Medical Condition
Prediction Strength
Diabetes!!
Merchant RA et al. doi.org/10.1371/journal.pone.0215476
All 21 medical condition
categories were predictable
from Facebook language
beyond chance.
18 categories better
predicted by demographics
+ Facebook language vs
demographics.
10 categories better
predicted by Facebook
language vs demographics.
Merchant RA et al. doi.org/10.1371/journal.pone.0215476
Merchant RA et al. doi.org/10.1371/journal.pone.0215476
Merchant RA et al. doi.org/10.1371/journal.pone.0215476
Merchant RA et al. doi.org/10.1371/journal.pone.0215476
SOCIALMEDIOME
What?
Why?
How?
is clinical
informatics
learn
informatics
can
informatics
improve
healthcare
Clinical Informatics

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Clinical Informatics

  • 1. Iris Thiele Isip Tan MD, MSc Professor 3, UP College of Medicine Chief, UP Medical Informatics Unit CLINICAL INFORMATICS
  • 3. It’s not just computers! Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938.
  • 4. Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938.
  • 5. Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938.
  • 6. Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938.
  • 7. “ Clinical informaticians transform health care by analyzing, designing, implementing, and evaluating information and communication systems that enhance individual and population health outcomes, improve patient care, and strengthen the clinician-patient relationship. ” – Gardner RM et al JAMIA 2009;16:153-157
  • 8. Gardner RM et al JAMIA 2009;16:153-157
  • 9. Kulikowski et al. J Am Med Inform Assoc 2012;19:931–938. MSc Health Informatics (UP Manila) Medical Informatics track (UPCM) Bioinformatics track (CAS)
  • 11. “We are drowning in information and starving for knowledge.” Rutherford D. Rogers http://www.infogineering.net/data-information-knowledge.htm
  • 12. Building a Health Information Infrastructure Why electronic health records? by InfowayInfoRoute https://youtu.be/Lo_3qOejQzI
  • 13. National eHealth Vision Philippines Photo by Doun, https://flic.kr/p/b5WFRK By 2020, eHealth will enable widespread access to health care services, health information and securely share and exchange patient information in support of safer, quality health care, more equitable and responsive health system for all the Filipino people by transforming the way information is used to plan, manage, deliver and monitor health services.
  • 14. IT-enabled health services By 2020 Philippine Health Information Exchange (PHIE) implementation EMR certification IT in all public health facilities National eHealth Vision
  • 15. Rule VIII. Governance & Accountablity Sec. 36 All health service providers and insurers are required to maintain a health information system on enterprise resource planning, human resource information system, electronic health records and electronic prescription log consistent with standards set by the DOH and Philhealth in consultation with the DICT and the NPC … RA 11223 Universal Healthcare Act
  • 16. RA 11223 Universal Healthcare Act Rule VIII. Governance & Accountablity Sec. 36 PhilHealth shall use its contracts to incentivize the incorporation of HIS, automation of clinical information, improvement of data quality, integration and use of telemedicine, and participation in regional or national health information networks.
  • 17. Art 4. Sec 3.3 Program Educational Objectives With additional training, graduates of the MD program may pursue any of the following careers to include: • General medical practitioner • Clinical specialist • Researcher/Medical Scientist/Innovator • Health professions teacher • Health administrator • Health information manager • Health economist • Health policy maker CHED Memorandum Order 18 Series of 2016
  • 18. Art 5. Sec 6.3 Minimum Curricular Content The minimum curricular content regardless of the curriculum design shall include the following: • Research, evidence-based medicine and medical informatics CHED Memorandum Order 18 Series of 2016
  • 20. Patient Safety & Clinical Informatics Assemble a complete picture of the patient, including tracking the course of disease and the effect of therapies over time Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407
  • 21. Patient Safety & Clinical Informatics Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407 Assembling the relevant medical knowledge
  • 22. REAL-WORLD DATA: Information on health care that is derived from multiple sources outside typical clinical research settings, including electronic health records (EHRs), claims and billing data, product and disease registries, and data gathered through personal devices and health applications. NEJM 2016;375(23):2293-7
  • 23. Patient Safety & Clinical Informatics Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407 Assembling the relevant medical knowledge Enhance adherence of clinical practice to tenets of EBM: prompting adherence to protocols/guidelines via computerized order entry
  • 24. Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407 Patient Safety & Clinical Informatics Applying timely and accurate knowledge of medicine to the patient’s current condition

  • 25. Clinical Decision Support Gather & make associations between pieces of information that may be missed because of sheer volume of data Bates et al JAMIA 2003;10:523-530
  • 26. Buch et al. Diabet Med 2018;35:495-7. Clinical guidelines will be delivered through apps rather than static documents.
  • 27. Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407 Patient Safety & Clinical Informatics Information systems to prevent, intercept and ameliorate harm Preventing mistakes
  • 28. https://mysugr.com/mysugr-bolus-calculator/ Insulin on board Blood glucose Carbs Previous injections Carbs/insulin ratio Insulin correction factor Blood glucose target MySugr Bolus Calculator
  • 29. https://www.uni-trier.de/index.php?id=44502&L=2 CASE-BASED REASONING Problem-solving paradigm in artificial intelligence Similar problems tend to have similar solutions Case base: collection of memorized chunks of experience (cases) Adaptive systems: new problem solving experience is retained and outdated experience is removed
  • 30. Brown D et al. Temporal case-based reasoning for type 1 diabetes mellitus bolus insulin decision support. Artificial Intelligence in Medicine 2018;85:28-42. Focus on helping patient directly (instead of aiding the clinician) RETAINS all successful cases Derives bolus suggestion from similar cases
  • 31. Brown D et al. Temporal case-based reasoning for type 1 diabetes mellitus bolus insulin decision support. Artificial Intelligence in Medicine 2018;85:28-42. CBR method can be adopted by insulin pumps, blood glucose monitors, PCs and as a web service
  • 32. CBR service in the cloud opens possibility of case sharing between subjects Brown D et al. Temporal case-based reasoning for type 1 diabetes mellitus bolus insulin decision support. Artificial Intelligence in Medicine 2018;85:28-42.
  • 33. Patient Safety & Clinical Informatics Kilbridge PM & Classen DC. JAMIA 2008;15(4):397-407 Assembling the relevant medical knowledge Enhance adherence of clinical practice to tenets of EBM: prompting adherence to protocols/guidelines via computerized order entry Clinical data mining to increase understanding of disease
  • 34. Can we predict individuals’ medical diagnoses from language posted on social media? Merchant RA et al. doi.org/10.1371/journal.pone.0215476
  • 35. Can we identify specific markers of disease from social media posts? Merchant RA et al. doi.org/10.1371/journal.pone.0215476 SOCIAL MEDIA + EMR
  • 36. Merchant RA et al. doi.org/10.1371/journal.pone.0215476
  • 37. Facebook alone Demographics alone Demographics and Facebook Medical Condition Prediction Strength Diabetes!! Merchant RA et al. doi.org/10.1371/journal.pone.0215476
  • 38. All 21 medical condition categories were predictable from Facebook language beyond chance. 18 categories better predicted by demographics + Facebook language vs demographics. 10 categories better predicted by Facebook language vs demographics. Merchant RA et al. doi.org/10.1371/journal.pone.0215476
  • 39. Merchant RA et al. doi.org/10.1371/journal.pone.0215476
  • 40. Merchant RA et al. doi.org/10.1371/journal.pone.0215476
  • 41. Merchant RA et al. doi.org/10.1371/journal.pone.0215476