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Build medical sensing capabilities to enable better 
trauma and critical care in austere (battlefield, disaster, 
rural) and definitive care environments 
LLNL-PRES-507331 
This work was performed under the auspices of the 
U.S. Department of Energy by Lawrence Livermore 
National Laboratory under contract DE-AC52- 
07NA27344. 
Lawrence Livermore National Security, LLC
 Electromagnetic sensor 
 Sends out pulses and looks for reflected 
Lawrence Livermore National Laboratory 
Radar 
echo signals 
 Used for motion detection, localization, 
and imaging
0 
0.5 
1 
4 
3 
2 
1 
0 
-1 
-2 
0 0.5 1 1.5 2 2.5 3 3.5 4 
diagnose tracking 
Lawrence Livermore National Laboratory 
out of hospital care 
situational 
awareness 
search and rescue 
imaging 
1 
2 
3
Various motion detection measurements made through rubble 
at Disaster City, Texas 
Lawrence Livermore National Laboratory 
Breathing signal 
Subject lying within concrete rubble pile; 
Fourier transform indicates strong breathing 
signal through concrete slabs.
2001 WTC-NYC 2005 Katrina 
Lawrence Livermore National Laboratory
•Case study of healthy volunteer 
•Live/dead detection for combat 
casualty care 
•High potential to benefit general 
public health monitoring 
•Subject in standing position 
•Respiratory and cardiac 
rhythm is readily observable 
•Impulse rhythm tracks well 
with EKG and pulse oximeter 
John Chang in collaboration with Walter Reed Army Institute of 
Research, Dr. FJ Pearce 
Lawrence Livermore National Laboratory
Small and compact 
Lawrence Livermore National Laboratory 
1 
0.5 
0 
-0.5 
-1 
-1.5 
0 50 100 150 
L parietal R parietal 
R L 
Hematoma 
CT Axial 
MRI Coronal 
Normal 
•In-field trauma diagnosis for combat 
casualty care 
•High potential for civilian application for 
emergency and critical cares 
Current Collaborations with UC Davis Medical Center and 
Neurosapient, Inc. 
•Chronic subdural 
hematoma 
•Bilateral asymmetry 
•Sensitivity to 
positioning 
•Signal attenuation 
•Peak shift to the 
right 
Signal amplitude 
(V) 
Skull Intracranial
Lawrence Livermore National Laboratory 
Vocal fold 
“machinery” 
Rear section of 
tracheal wall 
Cheek and 
Sinus wall 
motions
Early device Concept 
Currently CRADA 
Lawrence Livermore National Laboratory 
Detroit Sinai-Grace Hospital: 
Dr. Robert Dunne, MD, Clinical PI 
Detroit Receiving Hospital: 
Dr. Phillip Levy, MD, Clinical PI 
25 Patients (50 sides): 28 Patients (56 sides): 
18 Patients without a pneumothorax 21 Patients without a pneumothorax 
7 Patients with a pneumothorax 7 Patients with a pneumothorax 
92% (23 of 25 patients) correlation 
with radiographic results 
89.3% (25 of 28 patients) correlation with 
radiographic results 
2 Patients with false positives 2 Patients with false positive 
0 false negatives 1 Patient with false negative 
•Out of hospital diagnosis for traumatic chest injuries 
LLNL in collaboration with Electrosonics Medical, Inc, Detroit Sinai-Grace 
Hospital, and Detroit Receiving Hospital 
2007 R&D 100 Award, 
2008 Federal Laboratory Consortium Award 
Combined Summary 
Total Patients (sides) 53 Patients (106 sides) 
Total Correct Patients 48% 
Total Incorrect Patients 5% 
Overall Patient Accuracy 91% 
Total Correct Sides 90% 
Total Wrong Sides 16% 
Overall Sides Accuracy 85% 
Chest x ray of a pneumothorax. [Ref. Educational Computing for 
Health Technologies teaching web site, Michigan State University] 
Note the pleural line visible on the patient’s right side (image left 
side).
Suitable for use with humans 
 Low power 
 At least 100 times less than cell phone 
(< 0.001 mW/cm2) 
 Non-ionizing radiation 
 Non-invasive 
 No skin contact 
Suitable for use in remote locations, difficult terrain 
 Portable 
 Battery operated 
 Cost effective 
Lawrence Livermore National Laboratory 
MUIR Technology Specifications 
Frequency: GHz range 
Pulse repetition rate: 2x106 pulses/sec 
Pulse duration: 2x10-10 sec (200ps) 
Duty factor: 0.0004 
Peak power: 2.5mW/cm2 
Peak energy per pulse: 5x10-7 microJ/cm2
• Can perform multiple functions 
— Sensing (motion, breathing, heart-rate, bleeding, voice 
production, …) 
— Localization (position fixing) 
— Imaging 
• Advantages: 
— Small size 
— Low power 
— High resolution 
— Non hazardous 
Lawrence Livermore National Laboratory

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Medical Device Development Efforts Using the Micropower Ultrawideband Impulse Radar (MUIR) by John Chang, LLNL engineer

  • 1. Build medical sensing capabilities to enable better trauma and critical care in austere (battlefield, disaster, rural) and definitive care environments LLNL-PRES-507331 This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under contract DE-AC52- 07NA27344. Lawrence Livermore National Security, LLC
  • 2.  Electromagnetic sensor  Sends out pulses and looks for reflected Lawrence Livermore National Laboratory Radar echo signals  Used for motion detection, localization, and imaging
  • 3. 0 0.5 1 4 3 2 1 0 -1 -2 0 0.5 1 1.5 2 2.5 3 3.5 4 diagnose tracking Lawrence Livermore National Laboratory out of hospital care situational awareness search and rescue imaging 1 2 3
  • 4. Various motion detection measurements made through rubble at Disaster City, Texas Lawrence Livermore National Laboratory Breathing signal Subject lying within concrete rubble pile; Fourier transform indicates strong breathing signal through concrete slabs.
  • 5. 2001 WTC-NYC 2005 Katrina Lawrence Livermore National Laboratory
  • 6. •Case study of healthy volunteer •Live/dead detection for combat casualty care •High potential to benefit general public health monitoring •Subject in standing position •Respiratory and cardiac rhythm is readily observable •Impulse rhythm tracks well with EKG and pulse oximeter John Chang in collaboration with Walter Reed Army Institute of Research, Dr. FJ Pearce Lawrence Livermore National Laboratory
  • 7. Small and compact Lawrence Livermore National Laboratory 1 0.5 0 -0.5 -1 -1.5 0 50 100 150 L parietal R parietal R L Hematoma CT Axial MRI Coronal Normal •In-field trauma diagnosis for combat casualty care •High potential for civilian application for emergency and critical cares Current Collaborations with UC Davis Medical Center and Neurosapient, Inc. •Chronic subdural hematoma •Bilateral asymmetry •Sensitivity to positioning •Signal attenuation •Peak shift to the right Signal amplitude (V) Skull Intracranial
  • 8. Lawrence Livermore National Laboratory Vocal fold “machinery” Rear section of tracheal wall Cheek and Sinus wall motions
  • 9. Early device Concept Currently CRADA Lawrence Livermore National Laboratory Detroit Sinai-Grace Hospital: Dr. Robert Dunne, MD, Clinical PI Detroit Receiving Hospital: Dr. Phillip Levy, MD, Clinical PI 25 Patients (50 sides): 28 Patients (56 sides): 18 Patients without a pneumothorax 21 Patients without a pneumothorax 7 Patients with a pneumothorax 7 Patients with a pneumothorax 92% (23 of 25 patients) correlation with radiographic results 89.3% (25 of 28 patients) correlation with radiographic results 2 Patients with false positives 2 Patients with false positive 0 false negatives 1 Patient with false negative •Out of hospital diagnosis for traumatic chest injuries LLNL in collaboration with Electrosonics Medical, Inc, Detroit Sinai-Grace Hospital, and Detroit Receiving Hospital 2007 R&D 100 Award, 2008 Federal Laboratory Consortium Award Combined Summary Total Patients (sides) 53 Patients (106 sides) Total Correct Patients 48% Total Incorrect Patients 5% Overall Patient Accuracy 91% Total Correct Sides 90% Total Wrong Sides 16% Overall Sides Accuracy 85% Chest x ray of a pneumothorax. [Ref. Educational Computing for Health Technologies teaching web site, Michigan State University] Note the pleural line visible on the patient’s right side (image left side).
  • 10. Suitable for use with humans  Low power  At least 100 times less than cell phone (< 0.001 mW/cm2)  Non-ionizing radiation  Non-invasive  No skin contact Suitable for use in remote locations, difficult terrain  Portable  Battery operated  Cost effective Lawrence Livermore National Laboratory MUIR Technology Specifications Frequency: GHz range Pulse repetition rate: 2x106 pulses/sec Pulse duration: 2x10-10 sec (200ps) Duty factor: 0.0004 Peak power: 2.5mW/cm2 Peak energy per pulse: 5x10-7 microJ/cm2
  • 11. • Can perform multiple functions — Sensing (motion, breathing, heart-rate, bleeding, voice production, …) — Localization (position fixing) — Imaging • Advantages: — Small size — Low power — High resolution — Non hazardous Lawrence Livermore National Laboratory