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Alcohol consumption in the
   Greek population: is it related
      to abdominal obesity?


M. Kaklamanou, D. Kaklamanou, I. Ioannidis, C. Loupa, E. Kapantais



       Hellenic Medical Association for Obesity (HMAO), Athens, Greece
       First National Epidemiological Large Scale Survey on the
       Prevalence of Obesity in Greek Adults
Introduction I
  The metabolic syndrome is characterised by a
  group of metabolic risk factors. They include:
            Central obesity                                 Insulin resistance
            Atherogenic dyslipidemia                        Prothrombotic state
            Raised blood pressure                           Proinflammatory state

  BMI is a tool for measuring obesity, but when
  measuring abdominal obesity waist-to-hip ratio
  and waist circumference are used
  In this study waist-to-hip ratio measurements
  were used
                                                                                http://www.mayoclinic.com/
George A. Bray, Claude Bouchard, W.P.T. James; Handbook of Obesity, Marcel Dekker, New York, 1998
   Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                             2
   First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Introduction II

  Chronic alcohol consumption has both

      adverse effects (e.g. hypertension,
      cardiomyopathy and liver cancer, etc.)

      beneficial effects (the French paradox, etc.)


                                                                            http://www.mayoclinic.com/
Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                     3
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Aim of this study

is to explore a potential relation of alcohol
  consumption to abdominal obesity




Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 4
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Patients / Sample
                                                 The data analysed were
                                                 obtained from the first
                                                 national epidemiological
                                                 large scale survey on
                                                 the prevalence of
                                                 obesity in Greek adults,
                                                 conducted by the Hellenic
                                                 Medical Association for
                                                 Obesity.


Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 5
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
First national epidemiological
 survey on the prevalence of
       obesity in Greece
     Public schools throughout Greece were
 randomly chosen and questionnaires were
 filled by the students and all the members of
 their households
   The subpopulation used in the adult
 HMAO study were Greek men and women,
 20 to 70 years old

Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 6
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Methods I
WHR was calculated from waist and hip
circumference and the following categories were
used:



        Normal                               <1.00                 <0.85
        Pathologic                           >1.00                 >0.85
SPSS version 12.0 was used for statistical analysis,
student’s t-test and non parametric tests were used
                                                                                   http://www.eiep.gr/
Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                         7
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Methods II
 Alcohol consumption was calculated by
 adding the number of units consumed
 weekly, multiplied by the alcohol
 comprehensiveness of beverages (in this
 case beer, wine, whiskey and liqueur). The
 following categories were applied:
       0 mg      no alcohol
       <50 mg
                        moderate alcohol consumption
       50 - 150 mg
       150 - 300 mg
                           heavy alcohol consumption
       >300 mg
Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 8
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Results

  8090 men, age 44.6+10.5 years (x+SD),
  and 9313 women, 41.5+11.1 years,
  were included

  WHR was 0.97+0.3 and 0.87+0.3 in
  men and women, respectively

Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 9
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Waist-to-hip ratio
                   in men and women

     100%
                          32,2
                                                     42,3
      80%

      60%
                                                                          Above normal
      40%                 67,8                                            values (>1,00 in
                                                     57,7
                                                                          men and >0,85 in
      20%                                                                 women)
                                                                          Normal w/h (<1,00
                                                                          in men and <0,85
        0%
                                                                          in women)
                        men                     women


Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 10
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
How much alcohol do
                        men drink?


                               5,9 %
       12,8 %                                                       21,5 %




                                                                                no alcohol
                                                                                <50 mg
  31,2 %                                                                        51-150 mg
                                                         28,6                   151-300 mg
                                                          %                     >300 mg


Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 11
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
How much alcohol do
                     women drink?


                    10,0 %        1,2 0,3 %




                                                                                   no alcohol
                                                                                   <50 mg
     33,9 %                                                                        51-150 mg
                                                            54,6 %
                                                                                   151-300 mg
                                                                                   >300 mg


Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 12
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Results

  In men, WHR was associated to alcohol
  consumption (Kendall’s tau-b, p=0.044,
  statistically significant)

   This was not the case with women
  (p=0.823, N.S.)


Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 13
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Waist-to-hip ratio varies with alcohol
  consumption in men and women
                       1,05


                         1


                       0,95
  Waist-to-hip ratio




                        0,9


                       0,85


                        0,8


                       0,75
                              no alcohol   <50 mg   51-150 mg     151-300         <300 mg
                                                                    mg
                                                                                        men
                                            Alcohol consumption                         women



                                                     p=0.044 ,      p=0.823, Kendall’s tau-b
 Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                  14
 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Waist-to-hip ratio Vs alcohol
                                consumption in men
                            1,05


                              1
    Waist-to-hip ratio in




                            0,95


                             0,9

                                                                                   20-35 yrs
                            0,85                                                   35-50 yrs
                                                                                   >50 yrs

                             0,8
                                   no alcohol   <50 mg   51-150 mg   151-300   <301 mg
                                                                       mg
                                                   Alcohol consumption


Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 15
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Waist-to-hip ratio Vs alcohol
                              consumption in women
                          1,2
                                                                                  20-35 yrs
                                                                                  35-50 yrs
                          1,1
                                                                                  >50 yrs
     Waist-to-hip ratio




                           1


                          0,9


                          0,8


                          0,7
                                no alcohol   <50 mg   51-150 mg   151-300   <301 mg
                                                                    mg
                                                Alcohol consumption

Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 16
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Waist-to-hip ratio compared
with consumption of specific
      types of alcohol
                                    0,99
                          1,00                                       0,98
                                                                                        0,97
                                                      0,96

                          0,95
     Waist-to-hip ratio




                                                                            0,90
                                                                                            0,89
                          0,90             0,88           0,87                                     Men
                                                                                                   Women

                          0,85



                          0,80
                                 only beer        only wine      only liquer       only whiskey
                                                  Alcohol consumption


Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                           17
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Conclusions I

  In the Greek population, men drink
  more alcohol than women

  Women are more likely to have
  abnormal WHR than men


Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 18
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Conclusions II

  In addition to the effects of alcohol
  consumption to risk factors of various
  diseases, alcohol is related to
  abdominal obesity in men only




Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 19
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Discussion I
  Jequier introduced the alcohol paradox,
  which suggests increased alcohol induced
  energy intake without weight gain
  Other studies suggest that alcohol intake
  promotes leanness in women , but not in men
  This study shows that there is an association
  between waist-to-hip ratio to alcohol
  consumption in Greek men, but not in Greek
  women
                                                                Am J Epidemiol 1991;133:810-817
                   American Journal of Clinical Nutrition, Vol. 69, No. 2, 173-174, February 1999
Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 20
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Discussion II
  A survey conducted in Japan, which
  studied male self-defense officials,
  showed that alcohol consumption is
  strongly and independently associated
  with waist-to-hip ratio in men



                                                             Eur J Epidemiol. 1997 Dec;13(8):893-8
Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 21
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
Discussion III
 Simply looking at the total quantity of alcohol
 consumed over time obscures the importance
 of the pattern of alcohol consumption. 1-2
 drinks each day is associated with better
 health and greater longevity whereas
 consuming the same quantity (7-14 drinks)
 once a week is associates with negative
 health. The same quantity of alcohol can
 have either beneficial or harmful
 consequences depending on the pattern of its
 consumption.
                     National Health Interview Study (NHIS), American Journal of Epidemiology
Hellenic Medical Association for Obesity (HMAO), Athens, Greece
                                                                                                 22
First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults

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2005 14th eco2

  • 1. Alcohol consumption in the Greek population: is it related to abdominal obesity? M. Kaklamanou, D. Kaklamanou, I. Ioannidis, C. Loupa, E. Kapantais Hellenic Medical Association for Obesity (HMAO), Athens, Greece First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 2. Introduction I The metabolic syndrome is characterised by a group of metabolic risk factors. They include: Central obesity Insulin resistance Atherogenic dyslipidemia Prothrombotic state Raised blood pressure Proinflammatory state BMI is a tool for measuring obesity, but when measuring abdominal obesity waist-to-hip ratio and waist circumference are used In this study waist-to-hip ratio measurements were used http://www.mayoclinic.com/ George A. Bray, Claude Bouchard, W.P.T. James; Handbook of Obesity, Marcel Dekker, New York, 1998 Hellenic Medical Association for Obesity (HMAO), Athens, Greece 2 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 3. Introduction II Chronic alcohol consumption has both adverse effects (e.g. hypertension, cardiomyopathy and liver cancer, etc.) beneficial effects (the French paradox, etc.) http://www.mayoclinic.com/ Hellenic Medical Association for Obesity (HMAO), Athens, Greece 3 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 4. Aim of this study is to explore a potential relation of alcohol consumption to abdominal obesity Hellenic Medical Association for Obesity (HMAO), Athens, Greece 4 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 5. Patients / Sample The data analysed were obtained from the first national epidemiological large scale survey on the prevalence of obesity in Greek adults, conducted by the Hellenic Medical Association for Obesity. Hellenic Medical Association for Obesity (HMAO), Athens, Greece 5 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 6. First national epidemiological survey on the prevalence of obesity in Greece Public schools throughout Greece were randomly chosen and questionnaires were filled by the students and all the members of their households The subpopulation used in the adult HMAO study were Greek men and women, 20 to 70 years old Hellenic Medical Association for Obesity (HMAO), Athens, Greece 6 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 7. Methods I WHR was calculated from waist and hip circumference and the following categories were used: Normal <1.00 <0.85 Pathologic >1.00 >0.85 SPSS version 12.0 was used for statistical analysis, student’s t-test and non parametric tests were used http://www.eiep.gr/ Hellenic Medical Association for Obesity (HMAO), Athens, Greece 7 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 8. Methods II Alcohol consumption was calculated by adding the number of units consumed weekly, multiplied by the alcohol comprehensiveness of beverages (in this case beer, wine, whiskey and liqueur). The following categories were applied: 0 mg no alcohol <50 mg moderate alcohol consumption 50 - 150 mg 150 - 300 mg heavy alcohol consumption >300 mg Hellenic Medical Association for Obesity (HMAO), Athens, Greece 8 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 9. Results 8090 men, age 44.6+10.5 years (x+SD), and 9313 women, 41.5+11.1 years, were included WHR was 0.97+0.3 and 0.87+0.3 in men and women, respectively Hellenic Medical Association for Obesity (HMAO), Athens, Greece 9 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 10. Waist-to-hip ratio in men and women 100% 32,2 42,3 80% 60% Above normal 40% 67,8 values (>1,00 in 57,7 men and >0,85 in 20% women) Normal w/h (<1,00 in men and <0,85 0% in women) men women Hellenic Medical Association for Obesity (HMAO), Athens, Greece 10 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 11. How much alcohol do men drink? 5,9 % 12,8 % 21,5 % no alcohol <50 mg 31,2 % 51-150 mg 28,6 151-300 mg % >300 mg Hellenic Medical Association for Obesity (HMAO), Athens, Greece 11 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 12. How much alcohol do women drink? 10,0 % 1,2 0,3 % no alcohol <50 mg 33,9 % 51-150 mg 54,6 % 151-300 mg >300 mg Hellenic Medical Association for Obesity (HMAO), Athens, Greece 12 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 13. Results In men, WHR was associated to alcohol consumption (Kendall’s tau-b, p=0.044, statistically significant) This was not the case with women (p=0.823, N.S.) Hellenic Medical Association for Obesity (HMAO), Athens, Greece 13 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 14. Waist-to-hip ratio varies with alcohol consumption in men and women 1,05 1 0,95 Waist-to-hip ratio 0,9 0,85 0,8 0,75 no alcohol <50 mg 51-150 mg 151-300 <300 mg mg men Alcohol consumption women p=0.044 , p=0.823, Kendall’s tau-b Hellenic Medical Association for Obesity (HMAO), Athens, Greece 14 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 15. Waist-to-hip ratio Vs alcohol consumption in men 1,05 1 Waist-to-hip ratio in 0,95 0,9 20-35 yrs 0,85 35-50 yrs >50 yrs 0,8 no alcohol <50 mg 51-150 mg 151-300 <301 mg mg Alcohol consumption Hellenic Medical Association for Obesity (HMAO), Athens, Greece 15 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 16. Waist-to-hip ratio Vs alcohol consumption in women 1,2 20-35 yrs 35-50 yrs 1,1 >50 yrs Waist-to-hip ratio 1 0,9 0,8 0,7 no alcohol <50 mg 51-150 mg 151-300 <301 mg mg Alcohol consumption Hellenic Medical Association for Obesity (HMAO), Athens, Greece 16 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 17. Waist-to-hip ratio compared with consumption of specific types of alcohol 0,99 1,00 0,98 0,97 0,96 0,95 Waist-to-hip ratio 0,90 0,89 0,90 0,88 0,87 Men Women 0,85 0,80 only beer only wine only liquer only whiskey Alcohol consumption Hellenic Medical Association for Obesity (HMAO), Athens, Greece 17 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 18. Conclusions I In the Greek population, men drink more alcohol than women Women are more likely to have abnormal WHR than men Hellenic Medical Association for Obesity (HMAO), Athens, Greece 18 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 19. Conclusions II In addition to the effects of alcohol consumption to risk factors of various diseases, alcohol is related to abdominal obesity in men only Hellenic Medical Association for Obesity (HMAO), Athens, Greece 19 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 20. Discussion I Jequier introduced the alcohol paradox, which suggests increased alcohol induced energy intake without weight gain Other studies suggest that alcohol intake promotes leanness in women , but not in men This study shows that there is an association between waist-to-hip ratio to alcohol consumption in Greek men, but not in Greek women Am J Epidemiol 1991;133:810-817 American Journal of Clinical Nutrition, Vol. 69, No. 2, 173-174, February 1999 Hellenic Medical Association for Obesity (HMAO), Athens, Greece 20 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 21. Discussion II A survey conducted in Japan, which studied male self-defense officials, showed that alcohol consumption is strongly and independently associated with waist-to-hip ratio in men Eur J Epidemiol. 1997 Dec;13(8):893-8 Hellenic Medical Association for Obesity (HMAO), Athens, Greece 21 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults
  • 22. Discussion III Simply looking at the total quantity of alcohol consumed over time obscures the importance of the pattern of alcohol consumption. 1-2 drinks each day is associated with better health and greater longevity whereas consuming the same quantity (7-14 drinks) once a week is associates with negative health. The same quantity of alcohol can have either beneficial or harmful consequences depending on the pattern of its consumption. National Health Interview Study (NHIS), American Journal of Epidemiology Hellenic Medical Association for Obesity (HMAO), Athens, Greece 22 First National Epidemiological Large Scale Survey on the Prevalence of Obesity in Greek Adults