SlideShare ist ein Scribd-Unternehmen logo
1 von 50
Downloaden Sie, um offline zu lesen
Note on Forward-looking Statements

These presentations contain “forward-looking statements” as defined in the
Private Securities Litigation Reform Act of 1995. These statements are based on
current expectations of future events.
If underlying assumptions prove inaccurate or unknown risks or uncertainties
materialize, actual results could vary materially from the Company’s expectations
and projections.
Risks and uncertainties include general industry conditions and competition; economic
conditions, such as interest rate and currency exchange rate fluctuations; technological
advances and patents obtained by competitors; challenges inherent in new product
development, including obtaining regulatory approvals; domestic and foreign health
care reforms and governmental laws and regulations; and trends toward health care
cost containment.
Note on Forward-looking Statements

A further list and description of these risks, uncertainties and other factors
can be found in Exhibit 99 of the Company’s Annual Report on Form 10-K
for the fiscal year ended December 28, 2008. Copies of this Form 10-K,
as well as subsequent filings, are available online at www.sec.gov,
www.jnj.com or on request from the Company.

The Company does not undertake to update any forward-looking
statements as a result of new information or future events or developments.
Pharmaceuticals Business Review

              Sheri McCoy
 Worldwide Chairman, Pharmaceuticals Group
Agenda
Morning
Pharmaceuticals Group Overview    S. McCoy, Worldwide Chairman, Pharmaceuticals

Research & Development Overview   P. Stoffels, M.D., Global Head, Pharmaceuticals R&D

Neuroscience                      H. Manji, M.D., Global Therapeutic Head

Break

Cardiovascular & Metabolism       J. Waldstreicher, M.D., Chief Medical Officer

Infectious Diseases               R. Pomerantz, M.D., F.A.C.P., Global Therapeutic Head

Q&A Panel
Agenda
Afternoon
Lunch

Biotechnology & Immunology   J. Siegel, M.D., Chief Biotechnology Officer

Oncology                     B. Hait, M.D., Ph.D., Global Therapeutic Head

Q&A Panel

                             D. Caruso, Vice President, Finance
Closing Remarks
                             & Chief Financial Officer
Our Focus Today

• Johnson & Johnson overview
• Johnson & Johnson Pharmaceutical business
• Pharmaceutical market overview
• Johnson & Johnson growth strategies
• Johnson & Johnson R&D strategy
  and pipeline
Strength of Our Operating Model

                       Our Credo




 Broadly Based   Managed     Decentralized   Focused on
   in Human        for the   Management        People
  Health Care    Long Term    Approach       and Values
World’s Most Comprehensive and
Broadly Based Health Care Company
• 2008 Sales of $63.7 Billion
• Over 250 operating
  companies worldwide
• Leadership positions:
   – Pharmaceuticals (ethical and OTC)
   – Medical Devices & Diagnostics
   – Broad array of Consumer brands
2008 Johnson & Johnson Sales by Segment

$ U.S. Billions
Total Sales: $63.7B

                                                                              36%
      Medical Devices
                                                                             $23.1B                             25%
        & Diagnostics                                                                                                                                         Consumer
                             3.5%*                                                                             $16.0B
                                                                                                                                                               8.3%*
                                                                                  39%
     Pharmaceuticals                                                             $24.6B
                             3.1%*
* Operational Growth. Excludes the impact of foreign currency translation. Total sales growth can be found on the Investor Relations section of www.jnj.com
Johnson & Johnson Pharmaceuticals:
Competitively Positioned


 #7 Worldwide 2008 Market Rank
 #4 Global Biotech 2008 Market Rank

IMS Data
Johnson & Johnson Pharmaceuticals

2008 Sales $24.6 Billion
   3.1% Operationally

9 Products with sales $1 Billion+
REMICADEÂŽ         RISPERDALÂŽ CONSTAÂŽ
TOPAMAXÂŽ          CONCERTAÂŽ
PROCRITÂŽ/EPREXÂŽ ACIPHEXÂŽ/PARIETÂŽ
RISPERDALÂŽ        DURAGESICÂŽ/DUROGESICÂŽ
LEVAQUINÂŽ
2008 Pharmaceutical Growth Drivers

REMICADEÂŽ              INVEGAÂŽ   RISPERDALÂŽ CONSTAÂŽ   PREZISTAÂŽ   VELCADEÂŽ   TOPAMAXÂŽ




           13%*        117%*          13%*            163%*          41%*        11%*


* Operational Growth
Johnson & Johnson 2008 Global
Pharmaceutical Sales



            US
                   60%
                            40%
                                  OUS
Pharmaceuticals
Market
Overview
The Global Pharmaceuticals Market

• $750 billion* global market
• Projected CAGR of 3-6% through 2013*
       – U.S. growth slowing
       – Significant opportunity in emerging markets
       – Large and growing therapeutic areas




* IMS Health
Global Market Projections Moving Forward

• Growth projections in developed markets flat/declining
      – 5-year U.S. CAGR projections flat

• Emerging markets growth promising
      – Growth projected at 13-16% through 2013
        • 7 emerging markets will contribute 50%+ of growth in 2009
           • China will be 3rd largest Pharma market by 2011




IMS Data
Sales ($ U.S. Billions)




                                                                                                                                                                           0
                                                                                                                                                                               10
                                                                                                                                                                                    20
                                                                                                                                                                                         30
                                                                                                                                                                                              40
                                                                                                                                                                                                   50
                                                                                                                                                                                                        60
                                                                                                                                                                                                             70
                                                                                                                                                                                                                  80
                                                                                                                                                                 Oncology



                                                                                                                                                           Lipid Regulators


                                                                                                                                                               Respiratory
                                                                                                                                                                   Agents




Source: IMS Health, MIDAS, Therapy Forecaster 2007
                                                                                                                                                                Acid Pump
                                                                                                                                                                 Inhibitors


                                                                                                                                                              Anti-diabetes



                                                                                                                                                            Antipsychotics



                                                                                                                                                           Antidepressants


                                                                                                                                                             Angiotensin II
                                                                                                                                                              Antagonists
                                                                                                                                                                                                                                                                           Global Major Therapeutic Areas




                                                                                                                                                            Erythropoietins



                                                                                                                                                             Anti-epileptics
                                                                                                                                                                                                                              Major Therapeutic Areas Forecast 2007-2011




                                                                                                                                                             HIV Antivirals


                                                                                                                                                                   Platelet
                                                                                                                                                               Aggregation
                                                                                                                                                                                                                       2007




                                                                                                                                                                 Inhibitors

                                                                                                                                                                   Topical
                                                                                                                                                               Nasal Preps


                                                                                                                                                                  Antivirals
                                                                                                                                                                                                                       2011




                                                     By 2025, 50% of new patients in high growth TAs, such as diabetes and oncology, will come from BRIC
Sales ($ U.S. Billions)




                                                                                                                                                                           0
                                                                                                                                                                               10
                                                                                                                                                                                    20
                                                                                                                                                                                         30
                                                                                                                                                                                              40
                                                                                                                                                                                                   50
                                                                                                                                                                                                        60
                                                                                                                                                                                                             70
                                                                                                                                                                                                                  80
                                                                                                                                                                Oncology


                                                                                                                                                           Lipid Regulators


                                                                                                                                                               Respiratory
                                                                                                                                                                   Agents




Source: IMS Health, MIDAS, Therapy Forecaster 2007
                                                                                                                                                                Acid Pump
                                                                                                                                                                 Inhibitors


                                                                                                                                                            Anti-diabetes


                                                                                                                                                           Antipsychotics


                                                                                                                                                           Antidepressants


                                                                                                                                                             Angiotensin II
                                                                                                                                                              Antagonists
                                                                                                                                                                                                                                                                           Global Major Therapeutic Areas




                                                                                                                                                            Erythropoietins



                                                                                                                                                             Anti-epileptics
                                                                                                                                                                                                                              Major Therapeutic Areas Forecast 2007-2011




                                                                                                                                                            HIV Antivirals

                                                                                                                                                                   Platelet
                                                                                                                                                               Aggregation
                                                                                                                                                                                                                       2007




                                                                                                                                                                 Inhibitors

                                                                                                                                                                   Topical
                                                                                                                                                               Nasal Preps


                                                                                                                                                                  Antivirals
                                                                                                                                                                                                                       2011




                                                     By 2025, 50% of new patients in high growth TAs, such as diabetes and oncology, will come from BRIC
Industry Dynamics

• Significant unmet needs
• Aging demographics
• Rising cost of health care
• Evolving stakeholder influences
• Opportunity to reduce the burden
  of disease
Reducing the Burden of Disease

Addressing unmet
medical needs
Demonstrated, compelling
economic and clinical value
Differentiated products
Reducing the Burden of Disease:
Neuroscience

As many as 50 million people
globally with schizophrenia*
Cost of treating relapsed
patients 4x that of stable patients




* www.schizophrenia.com
Husseini Manji, M.D.
Global Therapeutic Head
Reducing the Burden of Disease:
Immunology

More than 200 million people live
with immunologic disorders
Rheumatoid arthritis patients
have 10x work disability rate
of general population
Jay P. Siegel, M.D.
Chief Biotechnology Officer
Reducing the Burden of Disease:
Cardiovascular Disease

Cardiovascular disease creates
a major cost burden on societies
Patients’ care remains challenging
Rates of venous thromboembolism
and atrial fibrillation continue to rise
Joanne Waldstreicher, M.D.
Chief Medical Officer
Reducing the Burden of Disease:
Diabetes

250 million people are living with
diabetes and the number is growing
Heart disease and stroke deaths
are 2 to 4 times higher in adults
with diabetes
Reducing the Burden of Disease:
Infectious Diseases

3% of the world’s population has
chronic hepatitis C
The majority are undiagnosed
80% of those diagnosed remain untreated
Consequences can include chronic
liver disease, cirrhosis, and liver cancer
Roger Pomerantz, M.D., F.A.C.P.
Global Therapeutic Head
Reducing the Burden of Disease:
Oncology

World’s leading cause of death by 2010
Cancer accounts for 13% of all
deaths worldwide
Bill Hait, M.D., Ph.D.
Global Therapeutic Head
Evolving Stakeholder Influences

• Changing level of risk tolerance
• Increasing demands for evidence
• Higher hurdles for differentiation
• Diverse stakeholders
• Consumer participation
Strategies for Growth

• Grow core business globally
• Successfully execute product launches
• Build robust pipeline
• Fuel emerging market growth
• Shape external environment
• Focus on our people
Grow Core Business Globally

• Market share growth
• Increase penetration
• Robust clinical strategies –
  life cycle management
• Geographic expansion
• Evolving commercial
  approaches
Grow Core Business Globally
“Pipeline in a product” examples
               ÂŽ
REMICADE                           STELARA™                              Rivaroxaban
Indications                        Indications                           Filings/Clinical Studies

Crohn’s disease                    Moderate to severe plaque psoriasis   VTE prevention post THR/TKR
                                                                         surgery
Rheumatoid arthritis
                                   Planned Filings/Clinical Studies      Planned Filings/Clinical Studies
Ankylosing spondylitis
                                   Crohn’s disease                       VTE treatment/long-term
Psoriatic arthritis                                                      secondary prevention
                                   Psoriatic arthritis
Ulcerative colitis                                                       Stroke prevention in patients
                                   Sarcoidosis
Pediatric Crohn’s disease                                                w/a-fib

Plaque psoriasis                                                         VTE prevention in hospitalized
                                                                         acute medically ill
Planned Filings/Clinical Studies
                                                                         Secondary prevention of CV
Pediatric ulcerative colitis                                             events in patients w/ACS
Successfully Execute Product Launches

• Expect to launch significant new
  products over 18 months
• Address unmet medical need
• Differentiation required
• Early and diverse stakeholder input
   – Patients
   – Physicians and providers
   – Regulators and payors

• Commercial execution
Build Robust Pipeline

• Five therapeutic areas
  – End-to-end
• Scientific strategies
• NMEs and major LEs
• Biologic and small molecules
• Internally discovered and
  externally sourced
Build Robust Pipeline
 Pharmaceuticals R&D Investment
                                  5-Year CAGR: 9.3%
    $ U.S. Billions

                                          $5.1


           $3.3




% to NTS   16.7%                          20.7%
           2003                            2008
Build Robust Pipeline
NME approvals and filings 2007-2010
 2007                                                  2008                        2009-2010
 Approved                                              Approved                    Approved
 DORIBAX™ (doripenem)                                  INTELENCE™ (etravirine)     STELARA™ (ustekinumab) (EU)
  Infectious diseases                                    Infectious diseases         Immunology
 Filed                                                 NUCYNTA™ (tapentadol IR)    PRILIGY® (dapoxetine) (EU)
 ZEFTERA™ (ceftobiprole)                                Pain                        Sexual health
   Infectious diseases                                 DORIBAX™ (doripenem) (EU)   SIMPONI™ (golimumab)
 INVEGA® SUSTENNA™                                      Infectious diseases          Immunology
 (paliperidone palmitate)                              Filed                       Planned Filings
   Neuroscience
                                                       Rivaroxaban                 DACOGEN™ (EU)
 STELARA™   (ustekinumab)                                Cardiovascular disease     Oncology
    Immunology
                                                       COMFYDE™ (carisbamate)      TMC278
                                                        Neuroscience                Infectious diseases
                                                       YONDELISÂŽ                   Telaprevir (EU)
                                                        Oncology                     Infectious diseases
                                                       SIMPONI™ (golimumab) (EU)
                                                         Immunology
Filings assumed to be in U.S. unless otherwise noted
Build Robust Pipeline
Planned Filings 2010-2013
Anti-NGF                    MTP inhibitor
 Neuroscience                Metabolism
Canagliflozin (SGLT-2)      Telaprevir (EU)
 Metabolism                  Infectious diseases
CNTO 136                    TMC207
 Immunology                  Infectious diseases
CNTO 328                    TMC278
 Oncology                    Infectious diseases
DACOGEN™ (EU)               TMC435
 Oncology                    Infectious diseases
Histamine H3 Antagonist
 Neuroscience
Fuel Emerging Market Growth

• Continued growth from
  core products
• Localized approaches
• Focus on sharing best practices
• Tap into global resources
  and capabilities
Tianjin Medical University Cancer Hospital
Shape the External Environment:
Reduce the Burden of Care
• Reduce and redefine cost of care
• Offer broad access programs
• Realize the promise of
  personalized medicine
Optimistic About Our Future

• Integrated global R&D
• Global reach with regional
  commercial teams
• Growth focus
Strategies for Growth

• Grow core business globally
• Successfully execute product launches
• Build robust pipeline
• Fuel emerging markets’ growth
• Shape external environment
• Focus on our people
Johnson & Johnson: Pharmaceutical Business Review

Weitere ähnliche Inhalte

Was ist angesagt?

Pharmaceutical Marketing Management
Pharmaceutical Marketing ManagementPharmaceutical Marketing Management
Pharmaceutical Marketing Management
Sheraz Pervaiz
 
Pharma Plan Presentation Powerpoint
Pharma Plan Presentation PowerpointPharma Plan Presentation Powerpoint
Pharma Plan Presentation Powerpoint
waschmaschine
 

Was ist angesagt? (20)

Losart (Losar
Losart (LosarLosart (Losar
Losart (Losar
 
Pharmaceutical marketing plan case study
Pharmaceutical marketing plan case studyPharmaceutical marketing plan case study
Pharmaceutical marketing plan case study
 
Marketing Plan
Marketing PlanMarketing Plan
Marketing Plan
 
Pharmaceutical marketing course
Pharmaceutical marketing coursePharmaceutical marketing course
Pharmaceutical marketing course
 
Strategic Management presentation for a Pharmaceutical Industry
Strategic Management presentation for a Pharmaceutical IndustryStrategic Management presentation for a Pharmaceutical Industry
Strategic Management presentation for a Pharmaceutical Industry
 
Johnson & Johnson Pharmaceutical Business Review
Johnson & Johnson Pharmaceutical Business ReviewJohnson & Johnson Pharmaceutical Business Review
Johnson & Johnson Pharmaceutical Business Review
 
Pharmaceutical Marketing Management
Pharmaceutical Marketing ManagementPharmaceutical Marketing Management
Pharmaceutical Marketing Management
 
Pharmaceutical Sales in Pakistan
Pharmaceutical Sales in PakistanPharmaceutical Sales in Pakistan
Pharmaceutical Sales in Pakistan
 
Pharma marketing
Pharma marketingPharma marketing
Pharma marketing
 
How Many Types of Marketing Strategies in Pharma Sector? - Ambit Bio Medix
How Many Types of Marketing Strategies in Pharma Sector? - Ambit Bio MedixHow Many Types of Marketing Strategies in Pharma Sector? - Ambit Bio Medix
How Many Types of Marketing Strategies in Pharma Sector? - Ambit Bio Medix
 
Pharma Plan Presentation Powerpoint
Pharma Plan Presentation PowerpointPharma Plan Presentation Powerpoint
Pharma Plan Presentation Powerpoint
 
Glenmark analyst ppt
Glenmark analyst pptGlenmark analyst ppt
Glenmark analyst ppt
 
New Launch Strategy & Product Cycle
New Launch Strategy & Product CycleNew Launch Strategy & Product Cycle
New Launch Strategy & Product Cycle
 
Novartis - Strategy Memo
Novartis - Strategy MemoNovartis - Strategy Memo
Novartis - Strategy Memo
 
Glaxo smith-kline-presentation
Glaxo smith-kline-presentationGlaxo smith-kline-presentation
Glaxo smith-kline-presentation
 
Best in-class Pharma Marketers
Best in-class Pharma MarketersBest in-class Pharma Marketers
Best in-class Pharma Marketers
 
New launching strategy of pharmaceutical brand
New launching strategy of pharmaceutical brandNew launching strategy of pharmaceutical brand
New launching strategy of pharmaceutical brand
 
Team 3
Team 3Team 3
Team 3
 
Marketing Presentation For 2011 MBA Program
Marketing Presentation For 2011 MBA ProgramMarketing Presentation For 2011 MBA Program
Marketing Presentation For 2011 MBA Program
 
Pharmaceutical Industry: The Challenges and the Opportunities
Pharmaceutical Industry: The Challenges and the OpportunitiesPharmaceutical Industry: The Challenges and the Opportunities
Pharmaceutical Industry: The Challenges and the Opportunities
 

Andere mochten auch (6)

johnson n johnson
johnson n johnsonjohnson n johnson
johnson n johnson
 
creativity and innovation of 3M
creativity and innovation of 3Mcreativity and innovation of 3M
creativity and innovation of 3M
 
JNJ pitch
JNJ pitch JNJ pitch
JNJ pitch
 
Johnson and johnson
Johnson and johnsonJohnson and johnson
Johnson and johnson
 
Johnson & Johnson pp
Johnson & Johnson ppJohnson & Johnson pp
Johnson & Johnson pp
 
Johnson & Johnson
Johnson & Johnson Johnson & Johnson
Johnson & Johnson
 

Ähnlich wie Johnson & Johnson: Pharmaceutical Business Review

Entrepreneurship in action
Entrepreneurship in actionEntrepreneurship in action
Entrepreneurship in action
LoreVlerick
 
10 05-18 web 2.0 weekly
10 05-18 web 2.0 weekly10 05-18 web 2.0 weekly
10 05-18 web 2.0 weekly
David Shore
 
10 06-08 web 2.0 weekly
10 06-08 web 2.0 weekly10 06-08 web 2.0 weekly
10 06-08 web 2.0 weekly
David Shore
 
Panel 4 carolina rossini
Panel 4  carolina rossiniPanel 4  carolina rossini
Panel 4 carolina rossini
Carolina Rossini
 
pepco MerillLynchPower&GasConferenceSept2007(final)
pepco MerillLynchPower&GasConferenceSept2007(final)pepco MerillLynchPower&GasConferenceSept2007(final)
pepco MerillLynchPower&GasConferenceSept2007(final)
finance41
 

Ähnlich wie Johnson & Johnson: Pharmaceutical Business Review (20)

Smaato - NOAH12 San Francisco
Smaato - NOAH12 San FranciscoSmaato - NOAH12 San Francisco
Smaato - NOAH12 San Francisco
 
Web 2.0 Weekly - June 22, 2010: "AOL Sells Bebo for Massive Loss"
Web 2.0 Weekly - June 22, 2010: "AOL Sells Bebo for Massive Loss"Web 2.0 Weekly - June 22, 2010: "AOL Sells Bebo for Massive Loss"
Web 2.0 Weekly - June 22, 2010: "AOL Sells Bebo for Massive Loss"
 
Entrepreneurship in action
Entrepreneurship in actionEntrepreneurship in action
Entrepreneurship in action
 
3. project charter, check sheet, pareto analysis & c&e diagram & matrix
3. project charter, check sheet, pareto analysis & c&e diagram & matrix3. project charter, check sheet, pareto analysis & c&e diagram & matrix
3. project charter, check sheet, pareto analysis & c&e diagram & matrix
 
Session 5 6
Session 5 6Session 5 6
Session 5 6
 
10 05-18 web 2.0 weekly
10 05-18 web 2.0 weekly10 05-18 web 2.0 weekly
10 05-18 web 2.0 weekly
 
Reducing Time to Market while ensuring Product Quality and Reliability to Gai...
Reducing Time to Market while ensuring Product Quality and Reliability to Gai...Reducing Time to Market while ensuring Product Quality and Reliability to Gai...
Reducing Time to Market while ensuring Product Quality and Reliability to Gai...
 
10 06-08 web 2.0 weekly
10 06-08 web 2.0 weekly10 06-08 web 2.0 weekly
10 06-08 web 2.0 weekly
 
Panel4 carolinarossini
Panel4 carolinarossiniPanel4 carolinarossini
Panel4 carolinarossini
 
Panel 4 carolina rossini
Panel 4  carolina rossiniPanel 4  carolina rossini
Panel 4 carolina rossini
 
Angel Ron: Banco Popular Gs conference Crisis Junio 2010
Angel Ron: Banco Popular Gs conference Crisis Junio 2010Angel Ron: Banco Popular Gs conference Crisis Junio 2010
Angel Ron: Banco Popular Gs conference Crisis Junio 2010
 
10 04-27 web 2.0 weekly
10 04-27 web 2.0 weekly10 04-27 web 2.0 weekly
10 04-27 web 2.0 weekly
 
High Equity Risk Premium in a Low Volatility World
High Equity Risk Premium in a Low Volatility WorldHigh Equity Risk Premium in a Low Volatility World
High Equity Risk Premium in a Low Volatility World
 
Only a few roads lead to rome the regulation of entry and broadband performan...
Only a few roads lead to rome the regulation of entry and broadband performan...Only a few roads lead to rome the regulation of entry and broadband performan...
Only a few roads lead to rome the regulation of entry and broadband performan...
 
pepco MerillLynchPower&GasConferenceSept2007(final)
pepco MerillLynchPower&GasConferenceSept2007(final)pepco MerillLynchPower&GasConferenceSept2007(final)
pepco MerillLynchPower&GasConferenceSept2007(final)
 
Weekly market review June 15, 2012
Weekly market review June 15, 2012Weekly market review June 15, 2012
Weekly market review June 15, 2012
 
Step Zero: New Qualitative Assessment Allowed for Assessing Goodwill
Step Zero: New Qualitative Assessment Allowed for Assessing Goodwill Step Zero: New Qualitative Assessment Allowed for Assessing Goodwill
Step Zero: New Qualitative Assessment Allowed for Assessing Goodwill
 
Cim & brilliant media introduction to econometrics
Cim & brilliant media introduction to econometricsCim & brilliant media introduction to econometrics
Cim & brilliant media introduction to econometrics
 
bs
bsbs
bs
 
Best Practices in Ranking and Prioritizing Your Partners
Best Practices in Ranking and Prioritizing Your PartnersBest Practices in Ranking and Prioritizing Your Partners
Best Practices in Ranking and Prioritizing Your Partners
 

Mehr von investorrelation

Q3 2009 Earning Report of Domino’s Pizza, Inc.
Q3 2009 Earning Report of Domino’s Pizza, Inc.Q3 2009 Earning Report of Domino’s Pizza, Inc.
Q3 2009 Earning Report of Domino’s Pizza, Inc.
investorrelation
 
Q3 2009 Earning Report of Fastenal Company
Q3 2009 Earning Report of Fastenal CompanyQ3 2009 Earning Report of Fastenal Company
Q3 2009 Earning Report of Fastenal Company
investorrelation
 
Q3 2009 Earning Report of Royal Philips Electronics
Q3 2009 Earning Report of Royal Philips ElectronicsQ3 2009 Earning Report of Royal Philips Electronics
Q3 2009 Earning Report of Royal Philips Electronics
investorrelation
 
Hewlett-Packard Q3 FY09 Earnings Announcement
Hewlett-Packard Q3 FY09 Earnings AnnouncementHewlett-Packard Q3 FY09 Earnings Announcement
Hewlett-Packard Q3 FY09 Earnings Announcement
investorrelation
 
Adobe to Acquire Omniture for $1.8 billion.
Adobe to Acquire Omniture for $1.8 billion.Adobe to Acquire Omniture for $1.8 billion.
Adobe to Acquire Omniture for $1.8 billion.
investorrelation
 
IBM Business Perspective
IBM Business PerspectiveIBM Business Perspective
IBM Business Perspective
investorrelation
 
Abbott: 2009 Annual Shareholders Meeting Remarks And Presentations
Abbott: 2009 Annual Shareholders Meeting Remarks And PresentationsAbbott: 2009 Annual Shareholders Meeting Remarks And Presentations
Abbott: 2009 Annual Shareholders Meeting Remarks And Presentations
investorrelation
 
Exxon Mobil Corporation at Barclays Capital 2009 CEO Energy Conference
Exxon Mobil Corporation at Barclays Capital 2009 CEO Energy ConferenceExxon Mobil Corporation at Barclays Capital 2009 CEO Energy Conference
Exxon Mobil Corporation at Barclays Capital 2009 CEO Energy Conference
investorrelation
 
Bayer Q2 2009 Results
Bayer Q2 2009 ResultsBayer Q2 2009 Results
Bayer Q2 2009 Results
investorrelation
 
"Oracle Insight for Investors" Educational Webcast - Oracle Fusion Middleware
"Oracle Insight for Investors" Educational Webcast - Oracle Fusion Middleware"Oracle Insight for Investors" Educational Webcast - Oracle Fusion Middleware
"Oracle Insight for Investors" Educational Webcast - Oracle Fusion Middleware
investorrelation
 
Financial Snapshot of IBM
Financial Snapshot of IBMFinancial Snapshot of IBM
Financial Snapshot of IBM
investorrelation
 
Chevron at Barclays Capital 2009 CEO Energy/Power Conference
Chevron at Barclays Capital 2009 CEO Energy/Power ConferenceChevron at Barclays Capital 2009 CEO Energy/Power Conference
Chevron at Barclays Capital 2009 CEO Energy/Power Conference
investorrelation
 
Intel 2008 Annual Report
Intel 2008 Annual ReportIntel 2008 Annual Report
Intel 2008 Annual Report
investorrelation
 
UBS Second Quarter 2009 Results
UBS Second Quarter 2009 ResultsUBS Second Quarter 2009 Results
UBS Second Quarter 2009 Results
investorrelation
 
UBS Debt Investor Presentation August 2009
UBS Debt Investor Presentation August 2009UBS Debt Investor Presentation August 2009
UBS Debt Investor Presentation August 2009
investorrelation
 
Investor Presentation of BMW Group 2009
Investor Presentation of BMW Group 2009Investor Presentation of BMW Group 2009
Investor Presentation of BMW Group 2009
investorrelation
 
Morgan Stanley: Barclays Financial Services Conference
Morgan Stanley: Barclays Financial Services ConferenceMorgan Stanley: Barclays Financial Services Conference
Morgan Stanley: Barclays Financial Services Conference
investorrelation
 
Earning results of Microsoft
Earning results of MicrosoftEarning results of Microsoft
Earning results of Microsoft
investorrelation
 
Paypal: The Global Internet Payment Network
Paypal: The Global Internet Payment NetworkPaypal: The Global Internet Payment Network
Paypal: The Global Internet Payment Network
investorrelation
 

Mehr von investorrelation (20)

Q3 2009 Earning Report of Domino’s Pizza, Inc.
Q3 2009 Earning Report of Domino’s Pizza, Inc.Q3 2009 Earning Report of Domino’s Pizza, Inc.
Q3 2009 Earning Report of Domino’s Pizza, Inc.
 
Q3 2009 Earning Report of Fastenal Company
Q3 2009 Earning Report of Fastenal CompanyQ3 2009 Earning Report of Fastenal Company
Q3 2009 Earning Report of Fastenal Company
 
Q3 2009 Earning Report of Royal Philips Electronics
Q3 2009 Earning Report of Royal Philips ElectronicsQ3 2009 Earning Report of Royal Philips Electronics
Q3 2009 Earning Report of Royal Philips Electronics
 
Hewlett-Packard Q3 FY09 Earnings Announcement
Hewlett-Packard Q3 FY09 Earnings AnnouncementHewlett-Packard Q3 FY09 Earnings Announcement
Hewlett-Packard Q3 FY09 Earnings Announcement
 
Adobe to Acquire Omniture for $1.8 billion.
Adobe to Acquire Omniture for $1.8 billion.Adobe to Acquire Omniture for $1.8 billion.
Adobe to Acquire Omniture for $1.8 billion.
 
IBM Business Perspective
IBM Business PerspectiveIBM Business Perspective
IBM Business Perspective
 
Abbott: 2009 Annual Shareholders Meeting Remarks And Presentations
Abbott: 2009 Annual Shareholders Meeting Remarks And PresentationsAbbott: 2009 Annual Shareholders Meeting Remarks And Presentations
Abbott: 2009 Annual Shareholders Meeting Remarks And Presentations
 
Exxon Mobil Corporation at Barclays Capital 2009 CEO Energy Conference
Exxon Mobil Corporation at Barclays Capital 2009 CEO Energy ConferenceExxon Mobil Corporation at Barclays Capital 2009 CEO Energy Conference
Exxon Mobil Corporation at Barclays Capital 2009 CEO Energy Conference
 
Bayer Q2 2009 Results
Bayer Q2 2009 ResultsBayer Q2 2009 Results
Bayer Q2 2009 Results
 
"Oracle Insight for Investors" Educational Webcast - Oracle Fusion Middleware
"Oracle Insight for Investors" Educational Webcast - Oracle Fusion Middleware"Oracle Insight for Investors" Educational Webcast - Oracle Fusion Middleware
"Oracle Insight for Investors" Educational Webcast - Oracle Fusion Middleware
 
Financial Snapshot of IBM
Financial Snapshot of IBMFinancial Snapshot of IBM
Financial Snapshot of IBM
 
Chevron at Barclays Capital 2009 CEO Energy/Power Conference
Chevron at Barclays Capital 2009 CEO Energy/Power ConferenceChevron at Barclays Capital 2009 CEO Energy/Power Conference
Chevron at Barclays Capital 2009 CEO Energy/Power Conference
 
Intel 2008 Annual Report
Intel 2008 Annual ReportIntel 2008 Annual Report
Intel 2008 Annual Report
 
WNS Factsheet
WNS FactsheetWNS Factsheet
WNS Factsheet
 
UBS Second Quarter 2009 Results
UBS Second Quarter 2009 ResultsUBS Second Quarter 2009 Results
UBS Second Quarter 2009 Results
 
UBS Debt Investor Presentation August 2009
UBS Debt Investor Presentation August 2009UBS Debt Investor Presentation August 2009
UBS Debt Investor Presentation August 2009
 
Investor Presentation of BMW Group 2009
Investor Presentation of BMW Group 2009Investor Presentation of BMW Group 2009
Investor Presentation of BMW Group 2009
 
Morgan Stanley: Barclays Financial Services Conference
Morgan Stanley: Barclays Financial Services ConferenceMorgan Stanley: Barclays Financial Services Conference
Morgan Stanley: Barclays Financial Services Conference
 
Earning results of Microsoft
Earning results of MicrosoftEarning results of Microsoft
Earning results of Microsoft
 
Paypal: The Global Internet Payment Network
Paypal: The Global Internet Payment NetworkPaypal: The Global Internet Payment Network
Paypal: The Global Internet Payment Network
 

KĂźrzlich hochgeladen

VIP Amritsar Call Girl 7001035870 Enjoy Call Girls With Our Escorts
VIP Amritsar Call Girl 7001035870 Enjoy Call Girls With Our EscortsVIP Amritsar Call Girl 7001035870 Enjoy Call Girls With Our Escorts
VIP Amritsar Call Girl 7001035870 Enjoy Call Girls With Our Escorts
sonatiwari757
 
Indapur - Virgin Call Girls Pune | Whatsapp No 8005736733 VIP Escorts Service...
Indapur - Virgin Call Girls Pune | Whatsapp No 8005736733 VIP Escorts Service...Indapur - Virgin Call Girls Pune | Whatsapp No 8005736733 VIP Escorts Service...
Indapur - Virgin Call Girls Pune | Whatsapp No 8005736733 VIP Escorts Service...
SUHANI PANDEY
 
Call Girls in Panjabi Bagh, Delhi 💯 Call Us 🔝9953056974 🔝 Escort Service
Call Girls in Panjabi Bagh, Delhi 💯 Call Us 🔝9953056974 🔝 Escort ServiceCall Girls in Panjabi Bagh, Delhi 💯 Call Us 🔝9953056974 🔝 Escort Service
Call Girls in Panjabi Bagh, Delhi 💯 Call Us 🔝9953056974 🔝 Escort Service
9953056974 Low Rate Call Girls In Saket, Delhi NCR
 
Corporate Presentation Probe May 2024.pdf
Corporate Presentation Probe May 2024.pdfCorporate Presentation Probe May 2024.pdf
Corporate Presentation Probe May 2024.pdf
Probe Gold
 
VVIP Pune Call Girls Handewadi WhatSapp Number 8005736733 With Elite Staff An...
VVIP Pune Call Girls Handewadi WhatSapp Number 8005736733 With Elite Staff An...VVIP Pune Call Girls Handewadi WhatSapp Number 8005736733 With Elite Staff An...
VVIP Pune Call Girls Handewadi WhatSapp Number 8005736733 With Elite Staff An...
SUHANI PANDEY
 
High Profile Call Girls in Pune (Adult Only) 8005736733 Escort Service 24x7 ...
High Profile Call Girls in Pune  (Adult Only) 8005736733 Escort Service 24x7 ...High Profile Call Girls in Pune  (Adult Only) 8005736733 Escort Service 24x7 ...
High Profile Call Girls in Pune (Adult Only) 8005736733 Escort Service 24x7 ...
SUHANI PANDEY
 
VIP Call Girls Mehsana 7001035870 Whatsapp Number, 24/07 Booking
VIP Call Girls Mehsana 7001035870 Whatsapp Number, 24/07 BookingVIP Call Girls Mehsana 7001035870 Whatsapp Number, 24/07 Booking
VIP Call Girls Mehsana 7001035870 Whatsapp Number, 24/07 Booking
dharasingh5698
 
B2 Interpret the brief.docxccccccccccccccc
B2 Interpret the brief.docxcccccccccccccccB2 Interpret the brief.docxccccccccccccccc
B2 Interpret the brief.docxccccccccccccccc
MollyBrown86
 
Ambala Escorts Service ☎️ 6378878445 ( Sakshi Sinha ) High Profile Call Girls...
Ambala Escorts Service ☎️ 6378878445 ( Sakshi Sinha ) High Profile Call Girls...Ambala Escorts Service ☎️ 6378878445 ( Sakshi Sinha ) High Profile Call Girls...
Ambala Escorts Service ☎️ 6378878445 ( Sakshi Sinha ) High Profile Call Girls...
mriyagarg453
 
Editing progress 20th march.docxxxxxxxxx
Editing progress 20th march.docxxxxxxxxxEditing progress 20th march.docxxxxxxxxx
Editing progress 20th march.docxxxxxxxxx
MollyBrown86
 

KĂźrzlich hochgeladen (20)

VIP Amritsar Call Girl 7001035870 Enjoy Call Girls With Our Escorts
VIP Amritsar Call Girl 7001035870 Enjoy Call Girls With Our EscortsVIP Amritsar Call Girl 7001035870 Enjoy Call Girls With Our Escorts
VIP Amritsar Call Girl 7001035870 Enjoy Call Girls With Our Escorts
 
Indapur - Virgin Call Girls Pune | Whatsapp No 8005736733 VIP Escorts Service...
Indapur - Virgin Call Girls Pune | Whatsapp No 8005736733 VIP Escorts Service...Indapur - Virgin Call Girls Pune | Whatsapp No 8005736733 VIP Escorts Service...
Indapur - Virgin Call Girls Pune | Whatsapp No 8005736733 VIP Escorts Service...
 
Q3 FY24 Earnings Conference Call Presentation
Q3 FY24 Earnings Conference Call PresentationQ3 FY24 Earnings Conference Call Presentation
Q3 FY24 Earnings Conference Call Presentation
 
Call Girls in Panjabi Bagh, Delhi 💯 Call Us 🔝9953056974 🔝 Escort Service
Call Girls in Panjabi Bagh, Delhi 💯 Call Us 🔝9953056974 🔝 Escort ServiceCall Girls in Panjabi Bagh, Delhi 💯 Call Us 🔝9953056974 🔝 Escort Service
Call Girls in Panjabi Bagh, Delhi 💯 Call Us 🔝9953056974 🔝 Escort Service
 
(👉゚9999965857 ゚)👉 Russian Call Girls Aerocity 👉 Delhi 👈 : 9999 Cash Payment F...
(👉゚9999965857 ゚)👉 Russian Call Girls Aerocity 👉 Delhi 👈 : 9999 Cash Payment F...(👉゚9999965857 ゚)👉 Russian Call Girls Aerocity 👉 Delhi 👈 : 9999 Cash Payment F...
(👉゚9999965857 ゚)👉 Russian Call Girls Aerocity 👉 Delhi 👈 : 9999 Cash Payment F...
 
Nicola Mining Inc. Corporate Presentation May 2024
Nicola Mining Inc. Corporate Presentation May 2024Nicola Mining Inc. Corporate Presentation May 2024
Nicola Mining Inc. Corporate Presentation May 2024
 
Corporate Presentation Probe May 2024.pdf
Corporate Presentation Probe May 2024.pdfCorporate Presentation Probe May 2024.pdf
Corporate Presentation Probe May 2024.pdf
 
Dattawadi ( Call Girls ) Pune 6297143586 Hot Model With Sexy Bhabi Ready Fo...
Dattawadi ( Call Girls ) Pune  6297143586  Hot Model With Sexy Bhabi Ready Fo...Dattawadi ( Call Girls ) Pune  6297143586  Hot Model With Sexy Bhabi Ready Fo...
Dattawadi ( Call Girls ) Pune 6297143586 Hot Model With Sexy Bhabi Ready Fo...
 
VVIP Pune Call Girls Handewadi WhatSapp Number 8005736733 With Elite Staff An...
VVIP Pune Call Girls Handewadi WhatSapp Number 8005736733 With Elite Staff An...VVIP Pune Call Girls Handewadi WhatSapp Number 8005736733 With Elite Staff An...
VVIP Pune Call Girls Handewadi WhatSapp Number 8005736733 With Elite Staff An...
 
Best investment platform in india-Falcon Invoice Discounting
Best investment platform in india-Falcon Invoice DiscountingBest investment platform in india-Falcon Invoice Discounting
Best investment platform in india-Falcon Invoice Discounting
 
High Profile Call Girls in Pune (Adult Only) 8005736733 Escort Service 24x7 ...
High Profile Call Girls in Pune  (Adult Only) 8005736733 Escort Service 24x7 ...High Profile Call Girls in Pune  (Adult Only) 8005736733 Escort Service 24x7 ...
High Profile Call Girls in Pune (Adult Only) 8005736733 Escort Service 24x7 ...
 
VIP Call Girls Mehsana 7001035870 Whatsapp Number, 24/07 Booking
VIP Call Girls Mehsana 7001035870 Whatsapp Number, 24/07 BookingVIP Call Girls Mehsana 7001035870 Whatsapp Number, 24/07 Booking
VIP Call Girls Mehsana 7001035870 Whatsapp Number, 24/07 Booking
 
B2 Interpret the brief.docxccccccccccccccc
B2 Interpret the brief.docxcccccccccccccccB2 Interpret the brief.docxccccccccccccccc
B2 Interpret the brief.docxccccccccccccccc
 
(‿ˠ‿) Independent Call Girls Laxmi Nagar 👉 9999965857 👈 Delhi : 9999 Cash Pa...
(‿ˠ‿) Independent Call Girls Laxmi Nagar 👉 9999965857 👈 Delhi  : 9999 Cash Pa...(‿ˠ‿) Independent Call Girls Laxmi Nagar 👉 9999965857 👈 Delhi  : 9999 Cash Pa...
(‿ˠ‿) Independent Call Girls Laxmi Nagar 👉 9999965857 👈 Delhi : 9999 Cash Pa...
 
(👉゚9999965857 ゚)👉 VIP Call Girls Greater Noida 👉 Delhi 👈 : 9999 Cash Payment...
(👉゚9999965857 ゚)👉 VIP Call Girls Greater Noida  👉 Delhi 👈 : 9999 Cash Payment...(👉゚9999965857 ゚)👉 VIP Call Girls Greater Noida  👉 Delhi 👈 : 9999 Cash Payment...
(👉゚9999965857 ゚)👉 VIP Call Girls Greater Noida 👉 Delhi 👈 : 9999 Cash Payment...
 
Balaji Nagar ( Call Girls ) Pune 6297143586 Hot Model With Sexy Bhabi Ready...
Balaji Nagar ( Call Girls ) Pune  6297143586  Hot Model With Sexy Bhabi Ready...Balaji Nagar ( Call Girls ) Pune  6297143586  Hot Model With Sexy Bhabi Ready...
Balaji Nagar ( Call Girls ) Pune 6297143586 Hot Model With Sexy Bhabi Ready...
 
Collective Mining | Corporate Presentation - May 2024
Collective Mining | Corporate Presentation - May 2024Collective Mining | Corporate Presentation - May 2024
Collective Mining | Corporate Presentation - May 2024
 
Vip Call Girls South Ex ➡️ Delhi ➡️ 9999965857 No Advance 24HRS Live
Vip Call Girls South Ex ➡️ Delhi ➡️ 9999965857 No Advance 24HRS LiveVip Call Girls South Ex ➡️ Delhi ➡️ 9999965857 No Advance 24HRS Live
Vip Call Girls South Ex ➡️ Delhi ➡️ 9999965857 No Advance 24HRS Live
 
Ambala Escorts Service ☎️ 6378878445 ( Sakshi Sinha ) High Profile Call Girls...
Ambala Escorts Service ☎️ 6378878445 ( Sakshi Sinha ) High Profile Call Girls...Ambala Escorts Service ☎️ 6378878445 ( Sakshi Sinha ) High Profile Call Girls...
Ambala Escorts Service ☎️ 6378878445 ( Sakshi Sinha ) High Profile Call Girls...
 
Editing progress 20th march.docxxxxxxxxx
Editing progress 20th march.docxxxxxxxxxEditing progress 20th march.docxxxxxxxxx
Editing progress 20th march.docxxxxxxxxx
 

Johnson & Johnson: Pharmaceutical Business Review

  • 1.
  • 2. Note on Forward-looking Statements These presentations contain “forward-looking statements” as defined in the Private Securities Litigation Reform Act of 1995. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could vary materially from the Company’s expectations and projections. Risks and uncertainties include general industry conditions and competition; economic conditions, such as interest rate and currency exchange rate fluctuations; technological advances and patents obtained by competitors; challenges inherent in new product development, including obtaining regulatory approvals; domestic and foreign health care reforms and governmental laws and regulations; and trends toward health care cost containment.
  • 3. Note on Forward-looking Statements A further list and description of these risks, uncertainties and other factors can be found in Exhibit 99 of the Company’s Annual Report on Form 10-K for the fiscal year ended December 28, 2008. Copies of this Form 10-K, as well as subsequent filings, are available online at www.sec.gov, www.jnj.com or on request from the Company. The Company does not undertake to update any forward-looking statements as a result of new information or future events or developments.
  • 4. Pharmaceuticals Business Review Sheri McCoy Worldwide Chairman, Pharmaceuticals Group
  • 5.
  • 6. Agenda Morning Pharmaceuticals Group Overview S. McCoy, Worldwide Chairman, Pharmaceuticals Research & Development Overview P. Stoffels, M.D., Global Head, Pharmaceuticals R&D Neuroscience H. Manji, M.D., Global Therapeutic Head Break Cardiovascular & Metabolism J. Waldstreicher, M.D., Chief Medical Officer Infectious Diseases R. Pomerantz, M.D., F.A.C.P., Global Therapeutic Head Q&A Panel
  • 7. Agenda Afternoon Lunch Biotechnology & Immunology J. Siegel, M.D., Chief Biotechnology Officer Oncology B. Hait, M.D., Ph.D., Global Therapeutic Head Q&A Panel D. Caruso, Vice President, Finance Closing Remarks & Chief Financial Officer
  • 8. Our Focus Today • Johnson & Johnson overview • Johnson & Johnson Pharmaceutical business • Pharmaceutical market overview • Johnson & Johnson growth strategies • Johnson & Johnson R&D strategy and pipeline
  • 9. Strength of Our Operating Model Our Credo Broadly Based Managed Decentralized Focused on in Human for the Management People Health Care Long Term Approach and Values
  • 10. World’s Most Comprehensive and Broadly Based Health Care Company • 2008 Sales of $63.7 Billion • Over 250 operating companies worldwide • Leadership positions: – Pharmaceuticals (ethical and OTC) – Medical Devices & Diagnostics – Broad array of Consumer brands
  • 11. 2008 Johnson & Johnson Sales by Segment $ U.S. Billions Total Sales: $63.7B 36% Medical Devices $23.1B 25% & Diagnostics Consumer 3.5%* $16.0B 8.3%* 39% Pharmaceuticals $24.6B 3.1%* * Operational Growth. Excludes the impact of foreign currency translation. Total sales growth can be found on the Investor Relations section of www.jnj.com
  • 12. Johnson & Johnson Pharmaceuticals: Competitively Positioned #7 Worldwide 2008 Market Rank #4 Global Biotech 2008 Market Rank IMS Data
  • 13. Johnson & Johnson Pharmaceuticals 2008 Sales $24.6 Billion 3.1% Operationally 9 Products with sales $1 Billion+ REMICADEÂŽ RISPERDALÂŽ CONSTAÂŽ TOPAMAXÂŽ CONCERTAÂŽ PROCRITÂŽ/EPREXÂŽ ACIPHEXÂŽ/PARIETÂŽ RISPERDALÂŽ DURAGESICÂŽ/DUROGESICÂŽ LEVAQUINÂŽ
  • 14. 2008 Pharmaceutical Growth Drivers REMICADEÂŽ INVEGAÂŽ RISPERDALÂŽ CONSTAÂŽ PREZISTAÂŽ VELCADEÂŽ TOPAMAXÂŽ 13%* 117%* 13%* 163%* 41%* 11%* * Operational Growth
  • 15. Johnson & Johnson 2008 Global Pharmaceutical Sales US 60% 40% OUS
  • 17. The Global Pharmaceuticals Market • $750 billion* global market • Projected CAGR of 3-6% through 2013* – U.S. growth slowing – Significant opportunity in emerging markets – Large and growing therapeutic areas * IMS Health
  • 18. Global Market Projections Moving Forward • Growth projections in developed markets flat/declining – 5-year U.S. CAGR projections flat • Emerging markets growth promising – Growth projected at 13-16% through 2013 • 7 emerging markets will contribute 50%+ of growth in 2009 • China will be 3rd largest Pharma market by 2011 IMS Data
  • 19. Sales ($ U.S. Billions) 0 10 20 30 40 50 60 70 80 Oncology Lipid Regulators Respiratory Agents Source: IMS Health, MIDAS, Therapy Forecaster 2007 Acid Pump Inhibitors Anti-diabetes Antipsychotics Antidepressants Angiotensin II Antagonists Global Major Therapeutic Areas Erythropoietins Anti-epileptics Major Therapeutic Areas Forecast 2007-2011 HIV Antivirals Platelet Aggregation 2007 Inhibitors Topical Nasal Preps Antivirals 2011 By 2025, 50% of new patients in high growth TAs, such as diabetes and oncology, will come from BRIC
  • 20. Sales ($ U.S. Billions) 0 10 20 30 40 50 60 70 80 Oncology Lipid Regulators Respiratory Agents Source: IMS Health, MIDAS, Therapy Forecaster 2007 Acid Pump Inhibitors Anti-diabetes Antipsychotics Antidepressants Angiotensin II Antagonists Global Major Therapeutic Areas Erythropoietins Anti-epileptics Major Therapeutic Areas Forecast 2007-2011 HIV Antivirals Platelet Aggregation 2007 Inhibitors Topical Nasal Preps Antivirals 2011 By 2025, 50% of new patients in high growth TAs, such as diabetes and oncology, will come from BRIC
  • 21. Industry Dynamics • Significant unmet needs • Aging demographics • Rising cost of health care • Evolving stakeholder influences • Opportunity to reduce the burden of disease
  • 22. Reducing the Burden of Disease Addressing unmet medical needs Demonstrated, compelling economic and clinical value Differentiated products
  • 23. Reducing the Burden of Disease: Neuroscience As many as 50 million people globally with schizophrenia* Cost of treating relapsed patients 4x that of stable patients * www.schizophrenia.com
  • 24. Husseini Manji, M.D. Global Therapeutic Head
  • 25. Reducing the Burden of Disease: Immunology More than 200 million people live with immunologic disorders Rheumatoid arthritis patients have 10x work disability rate of general population
  • 26. Jay P. Siegel, M.D. Chief Biotechnology Officer
  • 27. Reducing the Burden of Disease: Cardiovascular Disease Cardiovascular disease creates a major cost burden on societies Patients’ care remains challenging Rates of venous thromboembolism and atrial fibrillation continue to rise
  • 29. Reducing the Burden of Disease: Diabetes 250 million people are living with diabetes and the number is growing Heart disease and stroke deaths are 2 to 4 times higher in adults with diabetes
  • 30. Reducing the Burden of Disease: Infectious Diseases 3% of the world’s population has chronic hepatitis C The majority are undiagnosed 80% of those diagnosed remain untreated Consequences can include chronic liver disease, cirrhosis, and liver cancer
  • 31. Roger Pomerantz, M.D., F.A.C.P. Global Therapeutic Head
  • 32. Reducing the Burden of Disease: Oncology World’s leading cause of death by 2010 Cancer accounts for 13% of all deaths worldwide
  • 33. Bill Hait, M.D., Ph.D. Global Therapeutic Head
  • 34. Evolving Stakeholder Influences • Changing level of risk tolerance • Increasing demands for evidence • Higher hurdles for differentiation • Diverse stakeholders • Consumer participation
  • 35. Strategies for Growth • Grow core business globally • Successfully execute product launches • Build robust pipeline • Fuel emerging market growth • Shape external environment • Focus on our people
  • 36. Grow Core Business Globally • Market share growth • Increase penetration • Robust clinical strategies – life cycle management • Geographic expansion • Evolving commercial approaches
  • 37. Grow Core Business Globally “Pipeline in a product” examples ÂŽ REMICADE STELARA™ Rivaroxaban Indications Indications Filings/Clinical Studies Crohn’s disease Moderate to severe plaque psoriasis VTE prevention post THR/TKR surgery Rheumatoid arthritis Planned Filings/Clinical Studies Planned Filings/Clinical Studies Ankylosing spondylitis Crohn’s disease VTE treatment/long-term Psoriatic arthritis secondary prevention Psoriatic arthritis Ulcerative colitis Stroke prevention in patients Sarcoidosis Pediatric Crohn’s disease w/a-fib Plaque psoriasis VTE prevention in hospitalized acute medically ill Planned Filings/Clinical Studies Secondary prevention of CV Pediatric ulcerative colitis events in patients w/ACS
  • 38. Successfully Execute Product Launches • Expect to launch significant new products over 18 months • Address unmet medical need • Differentiation required • Early and diverse stakeholder input – Patients – Physicians and providers – Regulators and payors • Commercial execution
  • 39. Build Robust Pipeline • Five therapeutic areas – End-to-end • Scientific strategies • NMEs and major LEs • Biologic and small molecules • Internally discovered and externally sourced
  • 40. Build Robust Pipeline Pharmaceuticals R&D Investment 5-Year CAGR: 9.3% $ U.S. Billions $5.1 $3.3 % to NTS 16.7% 20.7% 2003 2008
  • 41. Build Robust Pipeline NME approvals and filings 2007-2010 2007 2008 2009-2010 Approved Approved Approved DORIBAX™ (doripenem) INTELENCE™ (etravirine) STELARA™ (ustekinumab) (EU) Infectious diseases Infectious diseases Immunology Filed NUCYNTA™ (tapentadol IR) PRILIGYÂŽ (dapoxetine) (EU) ZEFTERA™ (ceftobiprole) Pain Sexual health Infectious diseases DORIBAX™ (doripenem) (EU) SIMPONI™ (golimumab) INVEGAÂŽ SUSTENNA™ Infectious diseases Immunology (paliperidone palmitate) Filed Planned Filings Neuroscience Rivaroxaban DACOGEN™ (EU) STELARA™ (ustekinumab) Cardiovascular disease Oncology Immunology COMFYDE™ (carisbamate) TMC278 Neuroscience Infectious diseases YONDELISÂŽ Telaprevir (EU) Oncology Infectious diseases SIMPONI™ (golimumab) (EU) Immunology Filings assumed to be in U.S. unless otherwise noted
  • 42. Build Robust Pipeline Planned Filings 2010-2013 Anti-NGF MTP inhibitor Neuroscience Metabolism Canagliflozin (SGLT-2) Telaprevir (EU) Metabolism Infectious diseases CNTO 136 TMC207 Immunology Infectious diseases CNTO 328 TMC278 Oncology Infectious diseases DACOGEN™ (EU) TMC435 Oncology Infectious diseases Histamine H3 Antagonist Neuroscience
  • 43. Fuel Emerging Market Growth • Continued growth from core products • Localized approaches • Focus on sharing best practices • Tap into global resources and capabilities
  • 44. Tianjin Medical University Cancer Hospital
  • 45.
  • 46.
  • 47. Shape the External Environment: Reduce the Burden of Care • Reduce and redefine cost of care • Offer broad access programs • Realize the promise of personalized medicine
  • 48. Optimistic About Our Future • Integrated global R&D • Global reach with regional commercial teams • Growth focus
  • 49. Strategies for Growth • Grow core business globally • Successfully execute product launches • Build robust pipeline • Fuel emerging markets’ growth • Shape external environment • Focus on our people