for medical students. how cell communicate woith each other and involve in body functioning

5. Fig 15.3 The G Protein Cycle

9. G Protein-Linked Receptors

27. cAMP activates one or more kinases. What are phosphatases?

37. Activation of phospholipase C by protein-tyrosine kinases Phospholipase C-γ (PLC-γ) binds to activated receptor protein-tyrosine kinases via its SH2 domains. Tyrosine phosphorylation increases PLC-γ activity, stimulating the hydrolysis of PIP2.

38. The Formation of Inositol Triphosphate and Diacylglycerol PIP2 – phosphatidyl inositol-4,5-bisphophate IP3 – inositol-1,4,5-triphosphate PLC – phospholipase C DAG - diacylglycerol

41. DAG

42. Inositol Triphosphate 2 nd Messenger

43. The Structure and Function of the Calcium-Calmodulin Complex Kinases Phosphatases