There are several reasons why patients with pancreatic cancer experience pain, including inflammatory changes, ductal and parenchymal hypertension, and destruction of nerve fibers. Pain management options include medical management with medications like acetaminophen, NSAIDs, and opioids. Surgical options include procedures like the Whipple procedure. Interventional options involve nerve blocks and neurolysis of nerves like the splanchnic nerves and celiac plexus to provide pain relief. Care must be taken with techniques like celiac plexus block regarding patient preparation, indications and contraindications, and monitoring for complications.

4. Splanchnic Nerves and Coeliac Plexus

5. Coeliac Plexus Block

7. Classical Approach

8. Where to put in a needle?

11. Anterior Approach to Celiac Plexus

12. USG and CT Guidance