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ROLE OF FATS AND PROTEIN IN
ANIMAL REPRODUCTION
DR. IMRAN BASHIR AHMED
COLLEGE OF VETERINARY AND ANIMAL
SCIENCES JHANG
Nutrition and Reproduction
 In reproducing animals as in growing animals there is
an interaction b/w nutrition and production
 Nutrition requirement of animal for different purposes
i.e lactation, growth/fattening and reproductive
functions
 Nutritional deficiencies less likely to contribute to
decrease in male fertility
stages??
 In young animals nutrition can affect the age at which
they reach puberty(period of rapid growth during
puberty)
 In mature animals poor nutrition can reduce the
production of ova & spermatozoa, so that female either
fails to conceive or produce fewer offsprings
 In pregnancy, requires specific nutrients for the
maintenance and growth of fetus
 Peak lactation
 Inter-calving interval
What is the role of fats in
reproduction???
 Fats precursors for the synthesis of reproductive
hormones such as steroids and prostaglandins
 Polyunsaturated fatty acids (linolenic acid, lenoleic
acid, eicosapentaenoic acid and decahexaenoic acid)
inhibit pgf2α synthesis by decreasing availability of its
precursor arachidonic acid
 Fatty acid profile of the diet can be used to amplify
suppression of uterine synthesis of pgf2a during early
pregnancy in cattle which contribute to reduction in
EEM
Continue
 Diets rich in arachydonic acid lead to a better follicular
development and increase ovulation rate in cow by
stimulating PGF2a synthesis during follicular
developmental period
 Diets rich in linoleic acid should be given to the
animals during post-ovulation period in order to
stimulate progesterone synthesis and thus improves
conception rate by forming bigger CL
 Addition of fat supplements (PUFA’s) to diet of cows
will enhance reproduction by reducing anestrus period
after calving
 Unsaturated fatty acids, both mono- and poly-
unsaturated fats, are protective against ovulatory
infertility in females
Fats in diet
 Increase size of ovulatory follicle
 Increase no. of ovarian follicles
 Increase plasma conc. of progesterone
 Decrease secretion of PGF2a
 Increase lifespan of CL
 Improved fertility
 Increase insulin and growth hormones level
 Increase LH secretion
Fats for male sperm
 Polyunsaturated fats are important components of
sperm cell membranes and may influence the ability of
sperm to fertilize an egg
 Saturated fats may be harming the sperm, they may
be producing fewer and less active sperms.
 PAF’s are positively related to sperm morphology and
sperm concentration
 While saturated FA’s are negatively related to sperm
morphology and sperm concentration
Role of proteins in
reproduction???
Proteins are very important in
 Sperm capacitation
 Fertilization
 Early embryonic development
 Normal fetal growth and development
 Onset of puberty
 Increase ovulation rate
Adverse effects???
 Diets crude protein content of 17-19%, can cause
decreased fertility; it has been shown that cows fed in
this way have high concentrations of urea and
ammonia in blood and uterine fluids, which affects the
viability of sperm, oocytes and embryos
 In the case of cows, blood urea concentrations greater
than 20 mg /dl are associated with low fertility.
 Cows consuming diets high in protein, affecting
embryonic development, which is reflected in a
reduction of the proportion of embryos reaching the
blastocyst stage
Urea toxicity as protein
source???
 Increase abortion rates
 Increase incidence of retained placenta
 Increase calving intervals
Deficiencies/toxicities??
 Deficiencies / toxicities may primarily affect the anterior
pituitary / hypothalamus thus interfering normal LH and
FSH production
 Some deficiencies affects directly on gonads
 Inadequate intake and utilization of some nutrients
may result in decreased formation of luteal tissue and
thus decrease progesterone level
Deficiencies ???
 Inadequate intake of protein and energy during pregnancy
leads to low body condition at calving, this adds the
decrease in food intake during early lactation
(undernourishment)
 Increased glucose requirements for dairy animals, lead to
increase in the percentage of females in anoestrus and
increased calving interval
Minerals and vitamins
deficiencies???
 Phosphorus deficiency leads to poor fertility and effect
reproduction through suppressing estrus cycle
 Vit. A deficiency cause keratinization of vagina and
degeneration of testes
 Vit. E deficiency decreases reproductive performance
 Copper deficiency delay the return to estrus and hence
lengthen calving interval in cattle
 Zinc deficiency prevents spermatogenesis in bulls and
also cause increase in embryo mortality
References??
 G. Killian (2012) Fertility-associated proteins in male and
female reproductive fluids of cattle G. Killian
 P McDonald, R A Edwards, J F D Greenhalgh and C A
Morgan (Sixth edition) Animal Nutrition Book, Chapter 15
Feeding standards for reproduction
 Alejandro Cordova-Izquierdo (2016) Best Practices in
Animal Reproduction: Impact of Nutrition on Reproductive
Performance Livestock
ANY QUERIES/
AMBIGUITIES???
You can ask
Thanks

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Role of fats and protein in reproduction

  • 1. ROLE OF FATS AND PROTEIN IN ANIMAL REPRODUCTION DR. IMRAN BASHIR AHMED COLLEGE OF VETERINARY AND ANIMAL SCIENCES JHANG
  • 2. Nutrition and Reproduction  In reproducing animals as in growing animals there is an interaction b/w nutrition and production  Nutrition requirement of animal for different purposes i.e lactation, growth/fattening and reproductive functions  Nutritional deficiencies less likely to contribute to decrease in male fertility
  • 3. stages??  In young animals nutrition can affect the age at which they reach puberty(period of rapid growth during puberty)  In mature animals poor nutrition can reduce the production of ova & spermatozoa, so that female either fails to conceive or produce fewer offsprings  In pregnancy, requires specific nutrients for the maintenance and growth of fetus  Peak lactation  Inter-calving interval
  • 4. What is the role of fats in reproduction???  Fats precursors for the synthesis of reproductive hormones such as steroids and prostaglandins  Polyunsaturated fatty acids (linolenic acid, lenoleic acid, eicosapentaenoic acid and decahexaenoic acid) inhibit pgf2α synthesis by decreasing availability of its precursor arachidonic acid  Fatty acid profile of the diet can be used to amplify suppression of uterine synthesis of pgf2a during early pregnancy in cattle which contribute to reduction in EEM
  • 5. Continue  Diets rich in arachydonic acid lead to a better follicular development and increase ovulation rate in cow by stimulating PGF2a synthesis during follicular developmental period  Diets rich in linoleic acid should be given to the animals during post-ovulation period in order to stimulate progesterone synthesis and thus improves conception rate by forming bigger CL
  • 6.  Addition of fat supplements (PUFA’s) to diet of cows will enhance reproduction by reducing anestrus period after calving  Unsaturated fatty acids, both mono- and poly- unsaturated fats, are protective against ovulatory infertility in females
  • 7. Fats in diet  Increase size of ovulatory follicle  Increase no. of ovarian follicles  Increase plasma conc. of progesterone  Decrease secretion of PGF2a  Increase lifespan of CL  Improved fertility  Increase insulin and growth hormones level  Increase LH secretion
  • 8. Fats for male sperm  Polyunsaturated fats are important components of sperm cell membranes and may influence the ability of sperm to fertilize an egg  Saturated fats may be harming the sperm, they may be producing fewer and less active sperms.  PAF’s are positively related to sperm morphology and sperm concentration  While saturated FA’s are negatively related to sperm morphology and sperm concentration
  • 9. Role of proteins in reproduction??? Proteins are very important in  Sperm capacitation  Fertilization  Early embryonic development  Normal fetal growth and development  Onset of puberty  Increase ovulation rate
  • 10. Adverse effects???  Diets crude protein content of 17-19%, can cause decreased fertility; it has been shown that cows fed in this way have high concentrations of urea and ammonia in blood and uterine fluids, which affects the viability of sperm, oocytes and embryos  In the case of cows, blood urea concentrations greater than 20 mg /dl are associated with low fertility.
  • 11.  Cows consuming diets high in protein, affecting embryonic development, which is reflected in a reduction of the proportion of embryos reaching the blastocyst stage
  • 12. Urea toxicity as protein source???  Increase abortion rates  Increase incidence of retained placenta  Increase calving intervals
  • 13. Deficiencies/toxicities??  Deficiencies / toxicities may primarily affect the anterior pituitary / hypothalamus thus interfering normal LH and FSH production  Some deficiencies affects directly on gonads  Inadequate intake and utilization of some nutrients may result in decreased formation of luteal tissue and thus decrease progesterone level
  • 14. Deficiencies ???  Inadequate intake of protein and energy during pregnancy leads to low body condition at calving, this adds the decrease in food intake during early lactation (undernourishment)  Increased glucose requirements for dairy animals, lead to increase in the percentage of females in anoestrus and increased calving interval
  • 15. Minerals and vitamins deficiencies???  Phosphorus deficiency leads to poor fertility and effect reproduction through suppressing estrus cycle  Vit. A deficiency cause keratinization of vagina and degeneration of testes  Vit. E deficiency decreases reproductive performance  Copper deficiency delay the return to estrus and hence lengthen calving interval in cattle  Zinc deficiency prevents spermatogenesis in bulls and also cause increase in embryo mortality
  • 16. References??  G. Killian (2012) Fertility-associated proteins in male and female reproductive fluids of cattle G. Killian  P McDonald, R A Edwards, J F D Greenhalgh and C A Morgan (Sixth edition) Animal Nutrition Book, Chapter 15 Feeding standards for reproduction  Alejandro Cordova-Izquierdo (2016) Best Practices in Animal Reproduction: Impact of Nutrition on Reproductive Performance Livestock