1. Institute of Molecular Biology & Biotechnology Technologies Models Services … in the postgenomic era
2. IMBB Investigates ... Gene expression under stress & in differentiation The nervous system aging & neurodegeneration Development & differentiation Protein trafficking & molecular machines Mosquitoes and malaria
3. IMBB Develops ... Insect control systems ( Minos Biosystems , Bayer) DNA microchip prognostics ( Breast cancer ) New antibiotics (Pfitzer) Gene silencing technologies ( Crop protection ) Protein products ( Enzymes & Biopharmaceuticals) Acoustic biosensors
5. IMBB-Industry collaborations A variety of business models SecA inhibitors Pfizer Bayer SmithKlein Beecham BOEHRINGER MANNHEIM Chitin deacetylation Secretion Biotechnology Molecular Biology Enzymes Chitin synthase inhibitors Chitozyme, Marine Biopolymers BioLabs NEW ENGLAND
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7. The E. coli bacterium – 4.200 genes “ If we understand the biology of E. coli we will know the biology of the elephant” [J. Monod]
8. H 2 O lipid Bacterial secretion of proteins H 2 O T3S Sec
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10. Decision Diagram for the Exploitation of Scientific Discoveries Scientific Discovery Is it Useful? Invention Yes No Does it have an economic Potential? Yes Scientific Publication No Intellectual Property Does it need Protection? Yes No Patent Application No Business Secrete Does is provide Entrepreneurial Basis? No No Yes Technology Transfer Business Plan
12. Identification of insect chitin synthases BAYER AG Protection of IPR by patents (EPO, JPO, USPTO) Chitin exists in the cuticle and the peritrophic membrane of insects Chitin synthesis is a prime target for of pest control agents { Epicuticle (cuticulin layer) Exocuticle { Endocuticle { Epidermis { Procuticle (chitin and proteins) Synthesis zone Hemolymph
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14. Decision Diagram for the Exploitation of Scientific Discoveries Scientific Discovery Is it Useful? Invention Yes No Does it have an economic Potential? Yes Scientific Publication No Intellectual Property Does it need Protection? Yes No Patent Application No Business Secrete Does is provide Entrepreneurial Basis? No No Yes Technology Transfer Business Plan
20. “ Lefkippos” Technology Park of Attica Technology & Culture Park - Lavrion Thessaloniki Technology Park Science & Technology Park - Epirus Patras Science Park Science & Technology Park of Crete University of Ioannina University of Patras Foundation for Research & Technology - Hellas The Centre for Research & Technology Hellas NCRS “Demokritos” National Technical University of Athens
23. Main Objectives of Science and Technology Parks Technology transfer Regional or National Development
24. The Different Groups Interested in Science Parks Universities-Research Centers Government-Politicians Industry Venture Capital
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26. Objectives of the Government: Development - - - Creation of new jobs Improve the image of an area Increase the average income
27. Prerequisites Strategy for regional development Economic Incentives Industrial situation Degree of unemployment in area Degree of education in area Image of area Local politicians
28. Objectives of the industry Increase the number of suppliers, or potential clients Increase the number of inhabitants in the region and their average income Synergy with new firms Possibility for the location of subsidiaries of existing companies Improve image of area
29. Prerequisites Type of industry in area (big industry which needs suppliers, or small industries which need more clients) Size of companies Degree of R&D in companies Degree of high-tech of companies
32. - - - - Association with centers of excellence of different universities and Research Centers Select locations that have commercial, geographical or financial advantages Organization and management Access to International Technology Transfer and Venture Capital
