Memoria científica IACS 2010

Instituto Aragonés de Ciencias de la Salud

Memoria
Científica

3
4

I+CS

2010

INSTITUTO ARAGONES DE CIENCIAS DE LA SALUD
Avda. Alcalde Gómez Laguna, 25 Planta 3
50009 Zaragoza
Tel. 976 71 58 95
Fax: 976 71 46 70
www.ics.aragon.es

ÍNDICE
1.

Introducción ............................................................................................................................................ 6

2.

Indicadores de Producción Científica ................................................................................................... 9

3.

Relación de artículos ............................................................................................................................ 15

4.

Política de personal .............................................................................................................................. 54

5.

Servicios de Apoyo Común.................................................................................................................. 57

6.

Acciones estratégicas .......................................................................................................................... 73

7.

Formación.............................................................................................................................................. 77

8.

Espacios de investigación ................................................................................................................... 82

1. Introducción
Esta Memoria presenta la actividad científica desarrollada a lo largo del año 2010 en el Instituto Aragonés de
Ciencias de la Salud por el conjunto de centros asistenciales del Sistema Público de Salud de Aragón y por
investigadores y grupos de la Universidad de Zaragoza
Refleja la experiencia acumulada que, paso a paso, se ha ido adquiriendo desde hace años en esta
Comunidad y que se ha intensificado en los últimos, desde la creación del Instituto Aragonés de Ciencias de
la Salud.
Los Planes Científico y Estratégico de este Instituto plantean nuevos retos centrados en la consolidación y
proyección a nivel nacional e internacional de sus grupos de investigación y del propio Instituto. Son retos
inmediatos la definición de áreas científicas prioritarias -aquellas con especial potencial de generar
conocimiento científico de excelencia-, la puesta en marcha de medidas que permitan su consolidación y
crecimiento y el apoyo simultáneo a otras áreas y grupos que, a día de hoy, emergen con fuerza en el
panorama de la investigación en salud en Aragón.
Durante 2010 hemos visto cómo la actividad científica global aumenta día a día, cualitativa y
cuantitativamente, a la vez que se van concentrando y perfilando áreas temáticas de excelencia científica.
Las líneas clínicas de investigación en enfermedades del aparato digestivo, enfermedades cardiovasculares,
oncológicas, hematológicas, de salud mental, de pediatría, respiratorias y oftalmológicas son algunos buenos
ejemplos de ello. A ellas se suman otras de carácter transversal, como salud pública e investigación en
servicios sanitarios, ingeniería biomédica o la medicina regenerativa.
En términos de producción científica, en 2010 ha habido un incremento con respecto al año 2009. Y este
crecimiento, además, se concentra especialmente en Áreas como patología digestiva, cáncer o ingeniería
biomédica.
2010 ha sido un año decisivo en cuanto al impulso y coordinación de infraestructuras científicas. La acción
conjunta de investigadores y los órganos de gestión científica del Instituto ha permitido la incorporación a
plataformas de investigación relevantes a nivel nacional y con decidida proyección internacional como
CAIBER o a la Red Nacional de Biobancos.
La potenciación y consolidación de unos servicios de apoyo comunes de primer nivel ha sido una de las
acciones estratégicas fundamentales del Instituto durante 2010. Buenos ejemplos de ello es la oferta actual
de servicios de este Instituto en el campo de: genómica, proteómica, separación celular y citometría, cultivo
celular, microscopía e imagen, anatomía patológica, valoración funcional de animales, transgénesis, cirugía
experimental, estabulario, separación celular y secuenciación de ADN, apoyo metodológico, documentación,
apoyo a la investigación clínica o biobanco.
Algunas acciones científicas especialmente relevantes han sido el desarrollo del Programa Aragonés de
Medicina Regenerativa, una línea estratégica que, durante 2010, verán la luz los primeros trabajos científicos
en publicaciones internacionales de primer nivel liderados por investigadores de esta Comunidad. Otros
ejemplos de grandes proyectos, consolidados durante este período, han sido el Estudio de Cohorte AWHS
(Aragon Worker´s Health Study) o una infraestructura de investigación para seguimiento y evaluación de las
acciones emprendidas en el contexto del Plan de Prevención de Cáncer Colorrectal. Ambas acciones
suponen plataformas sólidas y con capacidad, por si solas, de generar nuevo conocimiento científico y han

6

sido potenciadas a través de convenios firmados con entidades a nivel regional y nacional (PAMER, AWHS,
SALUD, farmaindustria, etc).
Pero, sobre todo, la captación y retención de talentos es crucial para el futuro. En este sentido el Instituto está
haciendo un importante esfuerzo dirigido a la incorporación de jóvenes investigadores en las primeras etapas
de su carrera profesional, y de investigadores Miguel Servet y ARAID, con trayectoria investigadora
contrastada y que constituyen el germen de nuevos grupos de investigación. En 2010 se han incorporado dos
nuevos investigadores Miguel Servet y se ha obtenido la valoración favorable para otros dos nuevos
investigadores Miguel Servet y ARAID cuya incorporación está prevista en 2011. Asimismo el Instituto
Aragonés de Ciencias de la Salud ha promovido la intensificación de profesionales sanitarios, favoreciendo el
desarrollo de su actividad científica, un total de 9 profesionales cuentan, en este momento con una liberación
parcial de su actividad asistencial y 2 con una liberación total para el desarrollo de sus respectivas líneas de
investigación.
De forma complementaria, nuestro Plan de Formación en Investigación potencia la trayectoria investigadora
de los jóvenes talentos, que se forman y enriquecen en los grupos de investigación del Instituto. Asimismo, la
realización de jornadas científicas y seminarios, así como cursos de alto nivel destinados a investigadores
senior completa la oferta formativa del Plan de Formación potenciando la investigación de excelencia.
Conocer bien cuáles son nuestras fortalezas y las oportunidades del entorno ha permitido la incorporación de
un nutrido grupo de personas tanto investigadores como personal de apoyo, que han permitido, además,
mantener la tendencia creciente en cuanto a la creación de nuevos grupos de investigación. Son ellos los que
han permitido que este Instituto se sitúe, de nuevo en 2010, entre los de mayor nivel en la consecución de
proyectos en convocatorias competitivas a nivel nacional.

7

2

In dic ado res d e Prod ucc ión C ie n tífi ca

2. Indicadores de Producción Científica

Metodología
Las publicaciones se presentan agrupadas por hospital / centro. Se ha seguido, como criterio para relacionar
las publicaciones, el estar indexada en las bases de datos del Institute for Scientific Information (ISI),
utilizándose un algoritmo de búsqueda y clasificación basado en criterios geográficos y de institución. Estas
bases de datos están accesibles a través de la ISI's Web of Knowledge y permiten tener una relación de las
citaciones de los artículos así como de su Factor de Impacto (FI). Dentro de cada hospital / centro, se han
clasificado por el área temática en las que las incluye el propio ISI y se ha calculado el cuartil correspondiente
a cada área temática utilizando el ranking de las revistas indexadas en ISI. Se han eliminado aquellas
publicaciones que no aportan novedad científica relevante, como cartas al director, entre otras.
Las duplicidades existentes en publicaciones pueden deberse a que se trate de:
a. Una colaboración entre varios centros, por lo tanto aparece en varios centros
b. Una publicación recogida en una revista clasificada en varias áreas temáticas ISI. En este caso, el
factor de impacto es el mismo, pero los cuartiles pueden variar según el área temática.
El valor acumulado del Factor de Impacto se calcula teniendo en cuenta estas duplicidades, de manera que
no se incremente indebidamente.
Se han considerado las autorías que identifican explícitamente al investigador en el campo autor de la base
de datos y, por tanto, recogen filiación geográfica o institucional. Esto excluye las auditorias de grupo.
Las publicaciones de los centros de atención primaria se han tratado en conjunto, de acuerdo a la estrategia
del Programa Aragonés de Investigación en Atención Primaria (PAIAP).
En cuanto a las publicaciones de la Universidad de Zaragoza, se han incluido las de aquellos investigadores
incluidos en líneas coordinadas desde el Instituto, a través de la participación en convocatorias CIBER,
RETICs, proyectos o grupos de investigación reconocidos por el Gobierno de Aragón.
A continuación se muestran los principales indicadores de producción científica en 2010.

9

Tabla 1.1. Indicadores de producción científica
Indicador

Cálculo

Resultado

231/354

0,65

1.383,884

1.383,884

Factor Impacto total / Nº total proyectos públicos

1.383,884/109

12,69

FI Total / Nº IPs

1.383,884/84

16,47

5.083.533 /1.383,884

3.673,38€

7.199.873,80/393

18.320,29€

7.199.873,80/1.383,884

5.202,66€

7.199.873,80 /84

85.712,78€

Nº de artículos en revistas de 1er y 2º cuartil / Total
artículos con FI
Factor Impacto total

Financiación pública proyectos activos / FI Total
Coste por artículo según el total de ingresos
(Total Ingresos proyectos / Nº Artículos)
Coste por artículo según FI
(Ingresos proyectos/ Factor impacto)
Ingresos totales proyectos / Nº Investigadores
Principales

Tabla 1.2. Publicaciones por cuartiles y Factor Impacto
Cuartil

Nº Publicaciones

Factor de Impacto

Cuartil 1

136

1022,009

Cuartil 2

95

220,466

Cuartil 3

59

89,674

Cuartil 4

64

51,735

Sin Factor Impacto

39

-

Total

393

1.383,884

En este año 2010 se han publicado 393 artículos (38% en primer cuartil) con un factor de impacto total de
1.383,884. De las 354 publicaciones con FI, 231 se posicionan en primer y segundo cuartil, lo que supone un
65%.

10

Figura 1.1: Publicaciones por cuartiles

CUARTIL 4
18%

CUARTIL 1
38%

CUARTIL 3
17%

CUARTIL 2
27%

Figura 1.2: Factor de Impacto por Área Temática
Respiratorio
67,034
Salud Mental
76,043

Regenerativa
59,16
Oncología
212,242

Medicina Interna
78,6

Cardiología
79,193

Hematología
86,132

Digestivo 166,84

Genética 143,211
Ingeniería
Biomédica
122,382

11

Las áreas temáticas con un mayor factor de impacto son oncología, digestivo, genética e ingeniería
biomédica seguidas de hematología, cardiología, medicina interna, salud mental, respiratorio y medicina
regenerativa.
A continuación, estos gráficos representan el número de publicaciones totales según área temática, así como
las publicaciones de primer cuartil por área temática y su factor de impacto. Destaca el área de oncología con
un alto factor de impacto, seguida de digestivo y genética.
Figura 1.3: Publicaciones por Área Temática
250
200
150
100
50

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FI

Figura 1.4: Publicaciones de primer cuartil por Área Temática

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180
160
140
120
100
80
60
40
20
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Publicaciones

FI

12

Figura 1.5: Factor de impacto por centro

H Royo Villanova
35,003

Atención Primaria
20,665
Resto 32,98

H Barbastro 55,49

HCU Lozano
Blesa 547,807

I+CS 129,847

H San Jorge
149,954

Universidad
Zaragoza 393,164

H Miguel Servet
433,859

El Hospital Clínico Universitario Lozano Blesa, el Hospital Miguel Servet y la Universidad concentran el
grueso del factor de impacto. En términos generales, el número de publicaciones por centro, así como su
factor de impacto ha aumentado de manera exponencial con respecto al año anterior. Cabe destacar el
importante incremento de este factor de impacto en el Hospital de San Jorge, del Hospital de Barbastro, así
como de los investigadores adscritos a I+CS en comparación con el año 2009.
Figura 1.6: Publicaciones por centro
H Obispo Polanco
6
H Royo Villanova
14

H Calatayud 6
Resto 10
HCU Lozano
Blesa 129

H San Jorge 21

I+CS 24

Universidad de
Zaragoza 126
HU Miguel Servet
126

13

3

Re lac ió n de ar tícu los

14

3.

Relación de artículos

Atención Primaria

FI: 20,665

A continuación se relacionan los artículos con factor de impacto, clasificados según área temática en los que algún
autor procede de centros de Atención Primaria.

3.1.1

Atención Primaria

Bellon JA;Luna JD;Moreno B;Monton-Franco C;GildeGomez-Barragan MJ;Sanchez-Celaya M;az-Barreiros MA;Vicens C;Motrico
E;Martinez-Canavate MT;Olivan-Blazquez B;Vazquez-Medrano A;Sanchez-Artiaga MS;March S;Munoz-Garcia MD;Moreno-Peral
P;Nazareth I;King M;Torres-Gonzalez F. Psychosocial and sociodemographic predictors of attrition in a longitudinal study of major
depression in primary care: the predictD-Spain study.JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 2010;
64(10):874-884.
de Pedro-Cuesta J;Comin MC;Virues-Ortega J;Isla JA;Avellanal F;Cabero EA;Burzaco O;Castellote JM;Cieza A;Damian J;Forjaz
MJ;Frades B;Franco E;Larrosa LA;Magallon R;Garcia GM;Martinez C;Martin PM;Pastor-Barriuso R;Jimenez AP;Martinez
AP;Reed G;Ruiz C;.ICF-Based Disability Survey in a Rural Population of Adults and Older Adults Living in Cinco Villas,
Northeastern Spain:Design, Methods and Population Characteristics. Neuroepidemiology 2010; 35:72-82.
Fayed N;Garcia-Campayo J;Magallon R;Andres-Bergareche H;Luciano JV;Andres E;Beltran J;.Localized H-1-NMR spectroscopy
in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and Nacetylaspartate.Arthritis research & Therapy 2010; 12(4).
Perez-Palomares S;Olivan-Blazquez B;Magallon-Botaya R;De-la-Torre-Beldarrain M;Gaspar-Calvo E;Romo-Calvo L;GarciaLazaro R;Serrano-Aparicio B;.Percutaneous Electrical Nerve Stimulation Versus Dry Needling: Effectiveness in the Treatment of
Chronic Low Back pain. Journal of musculoskeletal pain. 2010;18 (1): 23-30
Rodero B;Casanueva B;Garcia-Campayo J;Roca M;Magallon R;del Hoyo YL;.Stages of chronicity in fibromyalgia and pain
catastrophising: a cross-sectional study.Bmc Musculoskel Dis.2010;11

3.1.2

Cardiovascular

Leiva A;Fajo M;Escriche L;Audera FJ;Lopez S;Martin MC;Gonzalez R;Tamborero G;Garcia EM;Duro R;Orueta R;Serra
F;D'agosto PP;Miralles J;Lorente P;Llobera J;Iglesias AA;Fernandez R;Colom MM;Buades AM;Moreno L;Vidal C;.Efficacy of a
brief multifactorial adherence-based intervention on reducing the blood pressure of patients with poor adherence: protocol for a
randomized clinical trial.Bmc Cardiovascular Dis.2010;44(10).

3.1.3

Geriatría y Gerontología

Martin-Carrasco M;Otermin P;Perez-Camo V;Pujol J;Aguera L;Martin MJ;Gobartt AL;Pons S;Balana M;.EDUCA study:
Psychometric properties of the Spanish version of the Zarit Caregiver Burden Scale.Aging Ment Health.2010;14(6):705-711

3.1.4

Medicina Interna

Aznar TL;Pueyo FJO;Ciria SB;Torrente MR;Aisa BS;Baratech ACG;.Diagnostic yield of cognitive tests applied in primary care.
Consistency and validity of screening tests.Aten Prim.2010;42(4):226-232
Cordoba-Garcia R;San Andres CS;.Three years of the smoking prevention law in Spain: The good and bad aspects.Aten
Prim.2010;42(2):63-65
Garcia RC;Andres CS;Bonel PS;.Occupational passive smoker. When will there be a new anti-smoking law?.Aten
Prim.2010;42(5):255-256

3.1.5

Oncología

Fernandez SP;Diaz SP;Calvino BL;Santamaria PG;Pillado TS;Monreal FA;Macia F;Calavera MAS;Macias AE;Ayerbes MV;Pazos
A;Lopez MR;Saez LG;Montserrat MR;Noguera JMS;Aliaga IM;Lujan LG;Rabadan MM;Nascimento CM;Pueyo O;Watts

15

MMB;Irigoyen EC;Abella MC;Pinilla M;Diagnosis delay and follow-up strategies in colorectal cancer. Prognosis implications: a
study protocol. 2010;10

3.1.6

Pediatría

Casas

AA;Martinez

GR;Villagrasa

MPS;Fernandez-Espinar

JF;Cosculluela

PB;Hernandez

MPC;Bonel

MFS;Galindo

ABS;Martinez CP;.Differences Between Reference Charts of Weight in Children Up to the Age of 18 Months.Nutr
Hosp.2010;25(5):838-844

3.1.7

Salud Mental

Fayed N;Garcia-Campayo J;Magallon R;Andres-Bergareche H;Luciano JV;Andres E;Beltran J;.Localized H-1-NMR spectroscopy
in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and Nacetylaspartate.Arthritis research & Therapy 2010; 12(4)
Martin-Carrasco M;Otermin P;Perez-Camo V;Pujol J;Aguera L;Martin MJ;Gobartt AL;Pons S;Balana M;.EDUCA study:
Psychometric properties of the Spanish version of the Zarit Caregiver Burden Scale.Aging Ment Health.2010;14(6):705-711
Rodero B;Casanueva B;Garcia-Campayo J;Roca M;Magallon R;del Hoyo YL;.Stages of chronicity in fibromyalgia and pain
catastrophising: a cross-sectional study.Bmc Musculoskel Dis.2010;11

3.1.8

Salud Pública y Servicios Sanitarios

Aibar MA;Laborda K;Conget F;Cornudella R;.Hypercoagulability state and endotelial injury in stable chronic obstructive pulmonary
disease patients.An Sist Sanit Navar.2010;33(1):43-50
Garcia-Ortiz L;Recio-Rodriguez JI;Martin-Cantera C;Cabrejas-Sanchez A;Gomez-Arranz A;Gonzalez-Viejo N;Nicolas EIS;PatinoAlonso MC;Gomez-Marcos MA;.Physical exercise, fitness and dietary pattern and their relationship with circadian blood pressure
pattern, augmentation index and endothelial dysfunction biological markers: EVIDENT study protocol. 2010;10
Martinez RG;Ibanez AM;Gomez PC;Villanueva ACG;Bergareche IA;Jaime CG;.Abdominal Girth Utility as a Method of Metabolic
Syndrome Screening in People with Hypertension.Revista Espanola De Salud Publica.2010;84(2):215-222
Navarro RG;.Use of the FRAX Algorithm to Calculate the Fracture Risk in Women of a Rural Area.Revista Espanola De Salud
Publica.2010;84(3):321-330

Hospital de Alcañiz

FI: 2,958

autor procede del Hospital de Alcañiz

3.1.9

Medicina Interna

Roa L;Monreal M;Carmona JA;Aguilar E;Coll R;Suarez C;.Treatment inertia in secondary prevention of cardiovascular disease.
FRENA registry.Med Clin-barcelona.2010;134(2):57-63

Hospital de Barbastro

FI: 55,49

autor procede del Hospital de Barbastro

3.1.10

Cardiovascular

Leiva A;Fajo M;Escriche L;Audera FJ;Lopez S;Martin MC;Gonzalez R;Tamborero G;Garcia EM;Duro R;Orueta R;Serra
F;D'agosto PP;Miralles J;Lorente P;Llobera J;Iglesias AA;Fernandez R;Colom MM;Buades AM;Moreno L;Vidal C;.Efficacy of a
brief multifactorial adherence-based intervention on reducing the blood pressure of patients with poor adherence: protocol for a
randomized clinical trial. BMC Cardiovascular disorders. 2010;10

16

3.1.11

Neurociencias

Gracia-Naya M;Huerta-Villanuev M;Rios-Gomez C;Latorre-Jimenez AM;Sanchez-Valiente S;Santos-Lasaosa S;Mauri-Llerda
JA;Garcia-Gomara MJ;rtal-Roy J;.Comparative study of the effectiveness of topiramate and nadolol in the preventive treatment of
episodic migraine in independent series of patients. Rev neurol. 2010;50 (9). 513-519
Modrego PJ;Fayed N;Errea JM;Rios C;Pina MA;Sarasa M;.Memantine versus donepezil in mild to moderate Alzheimer's disease:
a randomized trial with magnetic resonance spectroscopy.Eur J Neurol.2010;17(3):405-412

3.1.12

Oncología

Martin M;Rodriguez-Lescure A;Ruiz A;Alba E;Calvo L;Ruiz-Borrego M;Santaballa A;Rodriguez CA;Crespo C;Abad M;Dominguez
S;Florian J;Llorca C;Mendez M;Godes M;Cubedo R;Murias A;Batista N;Garcia MJ;Caballero R;de Alava E;.Molecular predictors of
efficacy of adjuvant weekly paclitaxel in early breast cancer. Breast cancer research and treatment.2010;123 (1):149-157
Martin M;Segui MA;Anton A;Ruiz A;Ramos M;Adrover E;Aranda I;Rodriguez-Lescure A;Grosse R;Calvo L;Barnadas A;Isla D;del
Prado PM;Borrego M;Zaluski J;Arcusa A;Munoz M;Vega JM;Mel JR;Munarriz B;Llorca C;Jara C;Alba E;Florian J;Li JF;GarciaAsenjo JA;Saez A;Rios M, Almenar S, Peiro G, Lluch A;. Adjuvant Docetaxel for High-Risk, Node-Negative Breast Cancer. New
England Journal of Medicine. 2010;363 (23):2200-2210

Hospital de Calatayud

FI: 12,61

autor procede del Hospital de Calatayud

3.1.13

Neurociencias

Gracia-Naya M;Huerta-Villanueva M;Rios-Gomez C;Latorre-Jimenez AM;Sanchez-Valiente S;Santos-Lasaosa S;Mauri-Llerda
JA;Garcia-Gomara MJ;Artal-Roy J;.Comparative study of the effectiveness of topiramate and nadolol in the preventive treatment
of episodic migraine in independent series of patients. Rev neurol. 2010;50 (9). 513-519

3.1.14

Oncología

Roca JM;Alonso V;Pericay C;Escudero P;Salud A;Losa F;Lopez LJ;Guasch I;Mendez M;Quintero-Aldana G;Grande C;Vicente
P;Arrivi A;Martin C;Moreno I;Garcia P;Anton I;Constenla M;Yubero A;Cirera L;.Cetuximab Given Every 2 Weeks plus Irinotecan Is
an Active and Safe Option for Previously Treated Patients with Metastatic Colorectal Cancer.Chemotherapy.2010;56(2):142-146

3.1.15

Pediatría

Rodriguez G;Gallego S;Breidenassel C;Moreno LA;Gottrand F;.Is liver transaminases assessment an appropriate tool for the
screening of non-alcoholic fatty liver disease in at risk obese children and adolescents?.Nutr Hosp.2010;25(5):712-717

3.1.16

Respiratorio

Dominguez A;Izquierdo C;Salleras L;Ruiz L;Sousa D;Bayas JM;Nebot M;Varona W;Celorrio JM;Carratala J;.Effectiveness of the
pneumococcal polysaccharide vaccine in preventing pneumonia in the elderly.Eur Respir J.2010;36(3):608-614

3.1.17

Salud Pública

Izquierdo C;Oviedo M;Ruiz L;Sintes X;Vera I;Nebot M;Bayas JM;Carratala J;Varona W;Sousa D;Celorrio JM;Salleras
L;Dominguez A;.Influence of socioeconomic status on community-acquired pneumonia outcomes in elderly patients requiring
hospitalization: a multicenter observational study. BMC Public Health. 2010;10

17

3.1.18
Arnal

Urología y Nefrología
LML;Gutierrez

AS;.Prevalence

of

BC;Izquierdo
chronic

kidney

MC;Garcia

OG;Alcaine

disease

in

patients

JMT;Garcia

SB;Orna

with

2

type

JAG;Juliani

diabetes

mellitus

BB;Hernandez-French
treated

in

primary

care.Nefrologia.2010;30(5):552-556

Hospital Clínico Universitario Lozano Blesa

FI: 547,807

autor procede del Hospital Clínico Universitario Lozano Blesa

3.1.19

Alergología

Elfau MTS;Sotillos MG;Claveria LF;Arazuri NS;Ballarin SM;Sanz CC;.Study of Cross-Reactivity Between Proton Pump Inhibitors.J
Invest Allerg Clin.2010;20(2):157-161

3.1.20

Biología

Perez-Lopez FR;Larrad-Mur L;Kallen A;Chedraui P;Taylor HS;.Gender Differences in Cardiovascular Disease: Hormonal and
Biochemical Influences.Reprod Sci.2010;17(6):511-531

3.1.21

Bioquímica y biología molecular

Perez-Lopez FR;Chedraui P;Cuadros-Lopez JL;.Bone Mass Gain During Puberty and Adolescence: Deconstructing Gender
Characteristics.Curr Med Chem.2010;17(5):453-466

3.1.22

Biotecnología

Arias A;Seral C;Gude MJ;Castillo FJ;.Molecular mechanisms of quinolone resistance in clinical isolates of Aeromonas caviae and
Aeromonas veronii bv. sobria.Int Microbiol.2010;13(3):135-141

3.1.23

Cardiovascular

Cabrerizo García JL, Zalba Etayo B, Pérez Calvo JI. .Prognostic value of occult renal failure in the acute coronary syndrome.Rev
Clin Esp.2010;210(4):204-201
Garcia JLC;Etayo BZ;Calvo JIP;.Prognostic value of glomerular filtrate in acute coronary syndrome: Cockcroft's index or MDRD
equation?.Med Clin-barcelona.2010;134(14):624-629
Murillo EC;Saez FD;Ruiz APA;Zorita JF;Alcantara AG;Aguado GH;Messa JBL;Rodriguez JAM;.The recommendations regarding
non-ST segment elevation acute coronary syndrome have been reviewed.Medicina Intensiva.2010;34(1):22-45
Olivera S;Amores B;Torralba MA;Calvo JIP;.Rare complication in a patient with giant cell arteritis.An Sist Sanit
Navar.2010;33(3):327-330
Perez Calvo JI;Fernandez de la Puebla Gimenez;.Neurologic involvement in type 1 Gaucher's disease.Med Clinbarcelona.2010;134(11):489-491
Ruiz

FJR;Abad

DS;Bergua

BS;.Therapeutic

alternatives

for

treating

heart

failure

in

elderly

patients.Salud

I

Ciencia.2010;17(5):428-431
Sanchez-Marteles M;Medina AM;Saiz EB;Laiglesia FR;Rodriguez JAN;Perez-Calvo JI;.Prognostic value of NT-proBNP in chronic
pulmonary disease exacerbation.Med Clin-barcelona.2010;135(10):441-446

3.1.24

Cirugía

Cristobal JA;Remon L;Del Buey MA;Montes-Mico R;.Multifocal intraocular lenses for unilateral cataract in children.J Cataract Refr
Surg.2010;36(12):2035-2040

18

Garcia-Gil FA;Lampreave F;Fuentes-Broto L;Carpintero R;Gonzalvo E;Garcia JJ;varez-Alegret R;Alfaro J;Orden I;Roda L;.Interalpha-trypsin inhibitor heavy chain 4 as a marker of acute rejection in pancreas allotransplantation in pigs.Transpl P.2010;42(8):30
Lamata P;Lamata F;Sojar V;Makowski P;Massoptier L;Casciaro S;Ali W;Studeli T;Declerck J;Elle OJ;Edwin B;.Use of the
Resection Map system as guidance during hepatectomy.Surg Endosc.2010;24(9):2327-2337
Martinez-Lostao L;Garcia-Alvarez F;Basanez G;egre-Aguaron E;Desportes P;Larrad L;Naval J;Martinez-Lorenzo MJ;Anel
A;.Liposome-Bound APO2L/TRAIL Is an Effective Treatment in a Rabbit Model of Rheumatoid Arthritis.Arthritis Rheumus.2010;62(8):2272-2282
Rodriguez-Galietero A;Martinez JVG;Del Buey A;Bescos JAC;.Use of Brimonidine Before LASIK With Femtosecond Lasercreated Flaps for the Correction of Myopia: A Contralateral Eye Study.J Refract Surg.2010;26(1):28-32
Serrano MT;Garcia-Gil A;Arenas J;Ber Y;Cortes L;Valiente C;Araiz JJ;.Outcome of liver transplantation using donors older than 60
year of age.Clin Transplant.2010;24(4):543-549
Valldeoriola F;Regidor I;Minguez-Castellanos A;Lezcano E;Garcia-Ruiz P;Rojo A;Salvador A;Castro A;Grandas F;Kulisevsky
J;Marti MJ;Martinez-Martin P;Relova L;Rumia J;Camara A;Burguera JA;Linazasoro G;de Val JL;Obeso J;Rodriguez-Oroz
MC;Tolosa E;.Efficacy and safety of pallidal stimulation in primary dystonia: results of the Spanish multicentric study. Journal of
neurology neurosurgery and psychiatry.2010;81(1):65-69

3.1.25

Dermatología

Torrelo A;Fernandez-Crehuet P;Del Prado E;Martes P;Hernandez-Martin A;De Diego V;Carapeto F;.Extensive Comedonal and
Cystic Acne in Patau Syndrome.Pediatr Dermatol.2010;27(2):199-200

3.1.26

Digestivo

Abian O;Vega S;Neira JL;Velazquez-Campoy A;.Conformational Stability of Hepatitis C Virus NS3 Protease.Biophys
J.2010;99(11):3811-3820
Abuli A;Bessa X;Gonzalez JR;Ruiz-Ponte C;Caceres A;Munoz J;Gonzalo V;Balaguer F;Fernandez-Rozadilla C;Gonzalez D;de
Castro L;Clofent J;Bujanda L;Cubiella J;Rene JM;Morillas JD;Lanas A;Rigau J;Garcia AM;Latorre M;Salo J;Banares FF;Arguello
L;Pena E;Vilella A.Susceptibility Genetic Variants Associated With Colorectal Cancer Risk Correlate With Cancer
Phenotype.Gastroenterology.2010;139(3):788-U129
Bhatt DL;Cryer BL;Contant CF;Cohen M;Lanas A;Schnitzer TJ;Shook TL;Lapuerta P;Goldsmith MA;Laine L;Scirica BM;Murphy
SA;Cannon CP;.Clopidogrel with or without Omeprazole in Coronary Artery Disease.New Engl J Med.2010;363(20):1909-1917
Borras E;Pineda M;Blanco I;Jewett EM;Wang F;Teule A;Caldes T;Urioste M;Martinez-Bouzas C;Brunet J;Balmana J;Torres
A;Cajal TRY;Sanz J;Perez-Cabornero L;Castellvi-Bel S;Alonso A;Lanas A;Gonzalez S;Moreno V;Gruber SB;Rosenberg
NA;Mukherjee B;Lazaro C;Capella G. MLH1 Founder Mutations with Moderate Penetrance in Spanish Lynch Syndrome Families.
Cancer Research.2010;70(19):7379-7391
Burmester G;Lanas A;Biasucci L;Hermann M;Lohmander S;Olivieri I;Scarpignato C;Smolen J;Stoevelaar H;.The appropriate use
of non-steroidal anti-inflammatory drugs in rheumatic disease: opinions of a multidisciplinary European expert panel.Ann Rheum
Dis.201
Casado-Arroyo R;Scheiman JM;Polo-Tomas M;Saini SD;del Rio A;Guastello E;Lanas A;.Underutilization of gastroprotection for
at-risk patients undergoing percutaneous coronary intervention: Spain compared with the United States.Aliment Pharm
Ther.2010;32(5):6
Chan FKL;Lanas A;Scheiman J;Berger MF;Nguyen H;Goldstein JL;.Celecoxib versus omeprazole and diclofenac in patients with
osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial.Lancet.2010;376(9736):173-179
Chan FKL;Cryer B;Goldstein JL;Lanas A;Peura DA;Scheiman JM;Simon LS;Singh G;Stillman MJ;Wilcox CM;Berger MF;Breazna
A;Dodge W;.A Novel Composite Endpoint to Evaluate the Gastrointestinal (GI) Effects of Nonsteroidal Antiinflammatory Drugs
Through the Entire GI Tract. Journal of rheumatology.2010;37(1):167-174

19

Dignass A;Van Assche G;Lindsay JO;Lemann M;Soderholm J;Colombel JF;Danese S;D'Hoore A;Gassull M;Gomollon F;Hommes
DW;Michetti P;O'Morain C;Oresland T;Windsor A;Stange EF;Travis SPL;.The second European evidence-based Consensus on
the diagnosis and management of Crohn's disease: Current management.Journal of Crohns & colitis.2010;4(1):28-62
Domenech R;Abian O;Bocanegra R;Correa J;Sousa-Herves A;Riguera R;Mateu MG;Fernandez-Megia E;Velazquez-Campoy
A;Neira

JL;.Dendrimers

as

potential

inhibitors

of

the

dimerization

of

the

capsid

protein

of

HIV-

1.Biomacromolecules.2010;11(8):2069-2078
Ferrandez A;Navarro M;Diez M;Sopena F;Roncales P;Polo-Tomas M;Sainz R;Lanas A;.Risk factors for advanced lesions
undetected at prior colonoscopy: not always poor preparation.Endoscopy.2010;42(12):1071-1076
Gisbert JP;Gomollon F;Hinojosa J;San Roman AL;.Adherence of gastroenterologists to European Crohn's and Colitis
Organisation consensus on ulcerative colitis: A real-life survey in Spain.J Crohns Colitis.2010;4(5):567-574
Gomollon

F;Gisbert

JP;.Must

immunomodulators

be

added

to

biological

treatment

in

inflammatory

bowel

disease?.Gastroenterologia Y Hepatologia.2010;33(1):43-53
Jimenez P;Piazuelo E;Cebrian C;Ortego J;Strunk M;Garcia-Gonzalez MA;Santander S;Alcedo J;Lanas A;.Prostaglandin EP2
receptor expression is increased in Barrett's oesophagus and oesophageal adenocarcinoma.Aliment Pharm Ther.2010;31(3):440451
Ladabaum U;Ferrandez A;Lanas A;.Cost-Effectiveness of Colorectal Cancer Screening in High-Risk Spanish Patients: Use of a
Validated Model to Inform Public Policy.Cancer Epidem Biomar.2010;19(11):2765-2776
Lanas A;.A review of the gastrointestinal safety data-a gastroenterologist's perspective.Rheumatology.2010;49:ii3-ii10
Lanas A;.Proton pump inhibitors and clopidogrel in a patient with cardiovascular risk factors: Cardiovascular versus
gastrointestinal risk?.Gastroenterol Hepatol.2010;33(1):1-5
Lanas A;Calvet X;Feu F;Ponce J;Gisbert JP;Barkun A;.First Spanish consensus on peptic ulcer bleeding management.Med Clinbarcelona.2010;135(13):608-616
Lanas A;Letelier C;Caamano E;Massardo T;Gonzalez P;Araya AV;.Frequency of positive anti thyroid peroxidase antibody titers
among normal individuals.Rev Med Chile.2010;138(1):15-21
Lanas A;Munoz M;Correa MC;Jimenez PM;.Analysis of differences between indication and prescription of gastroprotection
inpatients with risk factors treated with nonsteroidal anti-inflammatory agents: The GAP study.Gastroenterologia Y
Hepatologia.2010;33(2)
Lanas A;Tornero J;Zamorano JL;.Assessment of gastrointestinal and cardiovascular risk in patients with osteoarthritis who require
NSAIDs: the LOGICA study.Ann Rheum Dis.2010;69(8):1453-1458
Lopera JE;De Gregorio MA;.Fluoroscopic management of complications after colorectal stent placement.Gut Liver.2010;4(SUPPL.
1):S9-S18
Mearin F;Balboa A;Castells A;Dominguez JE;Esteve M;Garcia-Erce JA;Gisbert JP;Gomollon F;Panes J;Ponce J;.Iron deficiency
anemia and use of intravenous iron in digestive disease.Gastroenterologia Y Hepatologia.2010;33(8):605-613
Olivera-Gonzalez S;de Escalante-Yanguela B;Velilla-Soriano C;mores-Arriaga B;Martin-Fortea P;Navarro-Aguilar ME;.Metforminassociated hepatotoxicity.Medicina Intensiva.2010;34(7):483-487
Sostres C;Gargallo CJ;Arroyo MT;Lanas A;.Adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs, aspirin and coxibs)
on upper gastrointestinal tract.Best Pract Res Cl Ga.2010;24(2):121-132
Uribarrena-Amezaga R;Ortego J;Fuentes J;Raventos N;Parra P;Uribarrena-Echevarria R;.Prognostic value of lymph node
micrometastases in patients with colorectal cancer in Dukes stages A and B (T1-T4, N0, M0).Rev Esp Enferm
Dig.2010;102(3):176-181
yuso-Tejedor S;Angarica VE;Bueno M;Campos LA;AbiÃ¡n O;BernadÃ³ P;Sancho J;JimÃ©nez MA;.Design and structure of an
equilibrium protein folding intermediate: a hint into dynamical regions of proteins.J Mol Biol.2010;400(4):922-934

20

3.1.27

Endocrinología y Metabolismo

Chedraui P;Perez-Lopez FR;Blumel JE;Hidalgo L;Barriga J;.Hyperglycemia. in postmenopausal women screened for the
metabolic syndrome is associated to increased sexual complaints.Gynecol Endocrinol.2010;26(2):86-92
de los Terreros AS;Aguillo E;Faure E;Domene R;Ibanez J;Garijo C;.Reliability of Stereoscopic Nonmydriatic Retinography for
Assessment of Diabetic Macular Edema when Performed by Endocrinologists.Diabetes Technol The.2010;12(3):179-183
Perez-Lopez FR;Cuadros-Lopez JL;Fernandez-Alonso AM;Cuadros-Celorrio AM;Sabatel-Lopez RM;Chedraui P;.Assessing fatal
cardiovascular disease risk with the SCORE (Systematic Coronary Risk Evaluation) scale in post-menopausal women 10 years
after different hormone treatment regimens.Ginecological endocrinology.2010;26(7):533-538

3.1.28

Enfermedades infecciosas

Arias A;Seral C;Navarro F;Miro E;Coll P;Castillo FJ;.Plasmid-mediated QnrS2 determinant in an Aeromonas caviae isolate
recovered from a patient with diarrhoea.Clin Microbiol Infec.2010;16(7):1005-1007
Goni P;Aldana DE;Clavel A;Seral C;Remacha MA;Castillo FJ;.Prevalence of Giardia duodenalis assemblage B in humans in
Zaragoza and Leon, Spain.Enferm Infec Micr Cl.2010;28(10):710-712
Martin-Fortea MP;Aibar MA;de Escalante B;Olivera S;Letona S;Vitoria MA;Echezarreta C;.Peritoneal tuberculosis: a 16-year
review in a general hospital.Enferm Infec Micr Cl.2010;28(3):162-168
Olaechea PM;Insausti J;Blanco A;Luque P;.Epidemiology and impact of nosocomial infections.Medicina Intensiva.2010;34(4):256267
Trevino A;Garcia J;de Mendoza C;Benito R;Aguilera A;de Lejarazu RO;Ramos JM;Trigo M;Eiros JM;Rodriguez-Iglesias M;Torres
A;Calderon E;Hernandez A;Gomez C;Marcaida G;Soriano V;.Prevalence of HTLV-1/2 Infections in Spain: A Cross-Sectional
Hospital-Based Survey.AIDS research and human retroviruses.2010;26(8):861-864

3.1.29

Farmacología & Farmacia


3.1.30

Genética

Gaudet MM;Kirchhoff T;Green T;Vijai J;Korn JM;Guiducci C;Segre AV;Mcgee K;McGuffog L;Kartsonaki C;Morrison J;Healey
S;Sinilnikova OM;Stoppa-Lyonnet D;Mazoyer S;Gauthier-Villars M;Sobol H;Longy M;Frenay M;Hogervorst FBL;Rookus MA;Collee
JM;Hoogerbrugge N;Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer.Plos
Genetics.2010;6(10):e1001183
Rohatgi S;Clark D;Kline AD;Jackson LG;Pie J;Siu V;Ramos FJ;Krantz ID;Deardorff MA;.Facial Diagnosis of Mild and Variant
CdLS: Insights From a Dysmorphologist Survey.Am J Med Genet A.2010;152A(7):1641-1653

3.1.31

Geriatría y Gerontología

Chedraui P;Perez-Lopez FR;Mendoza M;Leimberg ML;Martinez MA;Vallarino V;Hidalgo L;.Assessment of self-esteem in midaged women.Maturitas.2010;66(1):77-82
Chedraui P;Perez-Lopez FR;Mendoza M;Leimberg ML;Martinez MA;Vallarino V;Hidalgo L;.Factors related to increased daytime
sleepiness during the menopausal transition as evaluated by the Epworth Sleepiness Scale.Maturitas.2010;65(1):75-80

3.1.32

Hematología

Azaceta G, Calasanz MJ, Dourdil V, Bonafonte E, Izquierdo I, Palomera L..Response to lenalidomide in a patient with
myelodysplastic syndrome with isolated del(5q) and JAK2 V617F mutation..Leuk Lymphoma.2010;51(10):1941-1943
de la Rubia J, Roig M, Ibáñez A, García I, Vera JA, Aguilar C, del Campo R, González N, Martínez R, Palomera L, Picón I,
Rodríguez JN, Sanz MA..Activity and safety of lenalidomide and dexamethasone in patients with multiple myeloma requiring
dialysis: a Spanish multicenter retrospective study.European Journal Haematology.2010;85(4):363-365

21

Mateos MV;Oriol A;Martinez-Lopez J;Gutierrez N;Teruel AI;de Paz R;Garcia-Larana J;Bengoechea E;Martin A;Mediavilla
JD;Palomera L;de Arriba F;Gonzalez Y;Hernandez JM;Sureda A;Bello JL;Bargay J;Penalver FJ;Ribera JM;Martin-Mateos
ML;Garcia-Sanz R;Cibeira MT.Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as
induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in
elderly patients with untreated multiple myeloma: a randomised trial. Lancet Oncology.2010;11(10):934-941
Otero R;Uresandi F;Jimenez D;Cabezudo MA;Oribe M;Nauffal D;Conget F;Rodriguez C;Cayuela A;.Home treatment in pulmonary
embolism.Thromb Res.2010;126(1):E1-E5

3.1.33

Ingeniería Biomédica

Mellado X;Cruz S;Artacho JM;Canellas M;.Reducing the number of segments in unidirectional MLC segmentations.Phys Med
Biol.2010;55(3):N75-N85

3.1.34

Inmunología

Elfau MTS;Sotillos MG;Claveria LF;Arazuri NS;Ballarin SM;Sanz CC;.Study of Cross-Reactivity Between Proton Pump Inhibitors.J
Invest Allerg Clin.2010;20(2):157-161
Garcia-Gil FA;Lampreave F;Fuentes-Broto L;Carpintero R;Gonzalvo E;Garcia JJ;varez-Alegret R;Alfaro J;Orden I;Roda L;.Interalpha-trypsin inhibitor heavy chain 4 as a marker of acute rejection in pancreas allotransplantation in pigs.Transpl P.2010;42(8):30
Trevino A;Garcia J;de Mendoza C;Benito R;Aguilera A;de Lejarazu RO;Ramos JM;Trigo M;Eiros JM;Rodriguez-Iglesias M;Torres
A;Calderon E;Hernandez A;Gomez C;Marcaida G;Soriano V;.Prevalence of HTLV-1/2 Infections in Spain: A Cross-Sectional
Hospital-Based Survey.AIDS research and human retroviruses.2010;26(8):861-864

3.1.35

Medicina Interna

Alfaro I;Ocana T;Castells A;Cordero C;Ponce M;Cajal TRY;Andreu M;Bujanda L;Herraiz M;Molina AJH;Fernandez-Banares
F;Riestra-Menendez S;Gargallo C;Ruiz A;Bustamante M;Blanco I;de Juan FM;.Characteristics of patients with familial
adenomatous polyposis in Spain. First results of the Spanish Registry of Familial Adenomatous Polyposis.Medicina
Clínica.2010;135(3):103-108
Cabrerizo JL;Zalba B;Perez JI;Ruiz F;.Leukocyte count as a risk factor for coronary adverse events among patients admitted for
an acute coronary syndrome.Rev Med Chile.2010;138(3):274-280
Duenas-Laita A;Putze GB;Alonso JR;Bajo A;Climent B;Corral E;Felices F;Ferrer A;Frutos MPH;Nogue S;Puiguriguer J;.Basis for
the clinical management of fire smoke poisoning 'Docohumo Madrid 2010'.Medicina Intensiva.2010;34(9):609-619
Duenas-Laita A;Putze GB;Alonso JR;Bajo A;Climent B;Corral E;Felices F;Ferrer A;Frutos MDH;Nogue S;Puiguriguer
J;.Fundamentals in the clinical management of intoxication due to smoke inhalation.Emergencias.2010;22(5):384-394
Mendoza MA;Ruiz FJM;Lasfuentes PC;Aznarez HN;Espanol AP;Hernandez MJR;.Tumour necrosis factor alpha antagonists in
established rheumatoid arthritis: Effectiveness comparative study.Med Clin-barcelona.2010;134(15):665-670

3.1.36

Microbiología

Arias A;Seral C;Gude MJ;Castillo FJ;.Molecular mechanisms of quinolone resistance in clinical isolates of Aeromonas caviae and
Aeromonas veronii bv. sobria.Int Microbiol.2010;13(3):135-141
Arias A;Seral C;Navarro F;Miro E;Coll P;Castillo FJ;.Plasmid-mediated QnrS2 determinant in an Aeromonas caviae isolate
recovered from a patient with diarrhoea.Clin Microbiol Infec.2010;16(7):1005-1007
Goni P;Aldana DE;Clavel A;Seral C;Remacha MA;Castillo FJ;.Prevalence of Giardia duodenalis assemblage B in humans in
Zaragoza and Leon, Spain.Enferm Infec Micr Cl.2010;28(10):710-712
Martin-Fortea MP;Aibar MA;de Escalante B;Olivera S;Letona S;Vitoria MA;Echezarreta C;.Peritoneal tuberculosis: a 16-year
review in a general hospital.Enferm Infec Micr Cl.2010;28(3):162-168

22

3.1.37

Neurociencias

Gracia-Naya M;Huerta-Villanueva M;Rios-Gomez C;Latorre-Jimenez AM;Sanchez-Valiente S;Santos-Lasaosa S;Mauri-Llerda
episodic migraine in independent series of patients.Revista de Neurología.2010;50(9):513-519
Llerda JAM;Cerda JM;Corral JA;Errazquin FP;Quilo G;Jimenez PM;.Management of Patients With Unclassified Epileptic Seizures
in Outpatient Clinics in Spain. Results of the RETO Study.Int J Neurosci.2010;120(11):711-716
Montanes-Rada F;Gastaminza-Perez X;Catala MA;Ruiz-Sanz F;Ruiz-Lazaro PM;Herreros-Rodriguez O;Garcia-Giral M;OrtizGuerra J;da-Diez JA;Mojarro-Praxedes D;Canto-Diez T;Mardomingo-Sanz MJ;Sasot-Llevadot J;Pamias M;Rey-Sanchez
F;.GEITDAH consensus on attention deficit hyperactivity disorder.Revista de neurología.2010;51(10):633-637
MC;Tolosa E;.Efficacy and safety of pallidal stimulation in primary dystonia: results of the Spanish multicentric study.Journal of
neurology neurosurgery and psychiatry.2010;81(1):65-69

3.1.38

Nutrición y Dietética

Ocon J;Garcia B;Benito P;Gimeno S;Garcia R;Lopez P;.Effect of Gastric Bypass on the Metabolic Syndrome and on
Cardiovascular Risk.Nutr Hosp.2010;25(1):67-71
Vila MP;Hernandez JA;de Lorenzo AG;Perez SC;Sanz ML;Garcia-Lorda P;Brosa M;.The burden of hospital malnutrition in Spain:
methods and development of the PREDyCES (R) study.Nutr Hosp.2010;25(6):1020-1024

3.1.39

Obstetricia y Ginecología

Chedraui P;Perez-Lopez FR;Mendoza M;Leimberg ML;Martinez MA;Vallarino V;Hidalgo L;.Assessment of self-esteem in midaged women.Maturitas.2010;66(1):77-82
Chedraui P;Perez-Lopez FR;Mendoza M;Leimberg ML;Martinez MA;Vallarino V;Hidalgo L;.Factors related to increased daytime
sleepiness during the menopausal transition as evaluated by the Epworth Sleepiness Scale.Maturitas.2010;65(1):75-80
Chedraui P;Perez-Lopez FR;Blumel JE;Hidalgo L;Barriga J;.Hyperglycemia in postmenopausal women screened for the metabolic
syndrome is associated to increased sexual complaints.Gynecol Endocrinol.2010;26(2):86-92
Chedraui P;Perez-Lopez FR;Mendoza M;Morales B;Martinez MA;Salinas AM;Hidalgo L;.Severe menopausal symptoms in middleaged women are associated to female and male factors.Arch Gynecol Obstet.2010;281(5):879-885
Perez-Lopez FR;Chedraui P;.Chagas disease in pregnancy: a non-endemic problem in a globalized world.Arch Gynecol
Obstet.2010;282(6):595-599
Perez-Lopez FR;Cuadros-Lopez JL;Fernandez-Alonso AM;Cuadros-Celorrio AM;Sabatel-Lopez RM;Chedraui P;.Assessing fatal
cardiovascular disease risk with the SCORE (Systematic Coronary Risk Evaluation) scale in post-menopausal women 10 years
after different hormone treatment regimens.Gynecological endocrinology.2010;26(7):533-538
Perez-Lopez FR;Larrad-Mur L;Kallen A;Chedraui P;Taylor HS;.Gender Differences in Cardiovascular Disease: Hormonal and
Biochemical Influences.Reprod Sci.2010;17(6):511-531

3.1.40

Oftalmología

Ascaso FJ;Cardenosa E;Cascante JM;Lario B;Perez D;Cristobal JA;.Acute postoperative endophthalmitis caused by Gemella
morbillorum.Eur J Ophthalmol.2010;20(3):608-611
Ascaso FJ;Lopez-Gallardo E;Del Prado E;Ruiz-Pesini E;Montoya J;.Macular lesion resembling adult-onset vitelliform macular
dystrophy in Kearns-Sayre syndrome with multiple mtDNA deletions.Clin Exp Ophthalmol.2010;38(8):812-816
Cristobal JA;Remon L;Del Buey MA;Montes-Mico R;.Multifocal intraocular lenses for unilateral cataract in children.J Cataract Refr
Surg.2010;36(12):2035-2040
Garcia-Ayuso D;Salinas-Navarro M;Agudo M;Cuenca N;Pinilla I;Vidal-Sanz M;Villegas-Perez MP;.Retinal ganglion cell numbers
and delayed retinal ganglion cell death in the P23H rat retina.Exp Eye Res.2010;91(6):800-810

23

Rodriguez-Galietero A;Martinez JVG;Del Buey A;Bescos JAC;.Use of Brimonidine Before LASIK With Femtosecond Lasercreated Flaps for the Correction of Myopia: A Contralateral Eye Study.J Refract Surg.2010;26(1):28-32

3.1.41

Oncología

Alvarez Lopez I;De La Haba Rodriguez J;Ruiz Simon A;Bellet Ezquerra M;Calvo Martinez L;Garcia Estevez L;Rodriguez Lescure
A;Isla Casado D;.SEOM clinical guidelines for the treatment of metastatic breast cancer.Clin Transl Oncol.2010;12(11):719-723
Antoniou AC;Beesley J;McGuffog L;Sinilnikova OM;Healey S;Neuhausen SL;Ding YC;Rebbeck TR;Weitzel JN;Lynch HT;Isaacs
C;Ganz PA;Tomlinson G;Olopade OI;Couch FJ;Wang XS;Lindor NM;Pankratz VS;Radice P;Manoukian S;Peissel B;Zaffaroni
D;Barile M;Viel A;Allavena.Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2
Mutation Carriers: Implications for Risk Prediction.Cancer Research.2010;70(23):9742-9754
Artal CA;Domine GM;Font PA;Garcia CR;Cobo DM;Isla CD;.SEOM clinical guidelines for the treatment of small-cell lung
cancer.Clin Transl Oncol.2010;12(1):27-31
Borgonon MP;Nin RM;Hernandez JJC;Casado DI;.SEOM clinical guidelines for the treatment of nasopharyngeal carcinoma.Clin
Transl Oncol.2010;12(11):749-752
Carcereny E;Ramirez JL;Sanchez-Ronco M;Isla D;Cobo M;Moran T;de Aguirre I;Okamoto T;Wei J;Provencio M;Lopez-Vivanco
G;Camps C;Domine M;Alberola V;Sanchez JM;Massuti B;Mendez P;Taron M;Rosell R;.Blood-based CHRNA3 single nucleotide
polymorphism and outcome in advanced non-small-cell lung cancer patients.Lung Cancer.2010;68(3):491-497
Castilla E;Pascual I;Roncales F;Aguirre E;Del RA;.Transient response of cardiac angiosarcoma to paclitaxel.Eur J Cancer
Care.2010;19(5):699-700
Ciruelos EM;Cortes J;Cortes-Funes H;Mayordomo JI;Bermejo B;Ojeda B;Garcia E;Rodriguez CA;Munoz M;Gomez P;Manso
L;Andres R;Lluch A;Saura C;Mendiola C;Baselga J;.Gemcitabine and capecitabine in previously anthracycline-treated metastatic
breast cancer: a multicenter phase II study (SOLTI 0301 trial).Annals of Oncology.2010;21(7):1442-1447
Codina JG;Dominguez PS;Pulla MP;Dominguez AR;Casado DI;.SEOM clinical guidelines for the treatment of diffuse large B-cell
lymphoma.Clin Transl Oncol.2010;12(11):765-769
Del Barco Berron S;Ciruelos Gil E;Tusquets Trias De Bes I;Munoz Mateu M;Sanchez Rovira P;Rodriguez Lescure A;Isla Casado
D;.SEOM clinical guidelines for the treatment of early breast cancer.Clin Transl Oncol.2010;12(11):711-718
Feliu J;Safont MJ;Salud A;Losa F;Garcia-Giron C;Bosch C;Escudero P;Lopez R;Madroal C;Bolaos M;Gil M;Llombart A;CastroCarpeo J;Gonzalez-Baron M;.Capecitabine and bevacizumab as first-line treatment in elderly patients with metastatic colorectal
cancer.British Journal of cancer.2010;102(10):1468-1473
Felip E;Rosell R;Maestre JA;Rodriguez-Paniagua JM;Moran T;Astudillo J;Alonso G;Borro JM;Gonzalez-Larriba JL;Torres
A;Camps C;Guijarro R;Isla D;Aguilo R;Alberola V;Padilla J;Sanchez-Palencia A;Sanchez JJ;Hermosilla E;Massuti B;.Preoperative
Chemotherapy Plus Surgery Versus Surgery Plus Adjuvant Chemotherapy Versus Surgery Alone in Early-Stage Non-Small-Cell
Lung Cancer.Journal of Clinical Oncology.2010;28(19):3138-3145
Fernandez-Martos C;Pericay C;Aparicio J;Salud A;Safont M;Massuti B;Vera R;Escudero P;Maurel J;Marcuello E;Mengual
JL;Saigi E;Estevan R;Mira M;Polo S;Hernandez A;Gallen M;Arias F;Serra J;Alonso V;.Phase II, Randomized Study of
Concomitant Chemoradiotherapy Followed by Surgery and Adjuvant Capecitabine Plus Oxaliplatin (CAPOX) Compared With
Induction CAPOX Followed by Concomitant Chemoradiotherapy and Surgery in Magnetic Resonance Imaging-Defined, Locally
Advanced Rectal Cancer: Grupo Cancer de Recto 3 Study.Journal of clinical oncology.2010;28(5):859-865
Garcia Gomez J;Perez Lopez ME;Garcia Mata J;Isla Casado D;.SEOM clinical guidelines for the treatment of antiemetic
prophylaxis in cancer patients receiving chemotherapy.Clin Transl Oncol.2010;12(11):770-774
Gravalos Castro C;Maurel Santasusana J;Rivera Herrero F;Salazar Soler R;Sevilla Garcia I;Sastre Valera J;Tabernero Caturla
JM;Gonzalez Flores E;Lomas Garrido M;Isla Casado D;.SEOM clinical guidelines for the adjuvant treatment of colorectal
cancer.Clin & Translational Oncology.2010;12(11):724-728
Losada MJV;Monterde VB;Arriaga BA;Perez AIF;Solares SS;Puyal MM;.Lung carcinosarcoma.Clin Transl Oncol.2010;12(4):303305

24

Martin-Broto J;Gutierrez A;Garcia-del-Muro X;Lopez-Guerrero JA;Martinez-Trufero J;de Sande LM;Lainez N;Maurel J;De Juan
A;Losa F;Andres R;Casado A;Tejido PG;Blanco R;Carles J;Bellmunt J;Gomez-Espana A;Ramos R;Martinez-Serra J;LlombartBosch A;Poveda A;.Prognostic time dependence of deletions affecting codons 557 and/or 558 of KIT gene for relapse-free
survival (RFS) in localized GIST: a Spanish Group for Sarcoma Research (GEIS) Study.Annals of oncology.2010;21(7):1552-1557
Prado PM;Borrego M;Zaluski J;Arcusa A;Munoz M;Vega JM;Mel JR;Munarriz B;Llorca C;Jara C;Alba E;Florian J;Li JF;GarciaAsenjo

JA;Saez

A.

Adjuvant

Docetaxel

for

High-Risk,

Node-Negative

Breast

Cancer.New

England

Journal

of

Medicine.2010;363(23):2200-2210
Martinez-Trufero J;Isla D;Adansa JC;Irigoyen A;Hitt R;Gil-Arnaiz I;Lambea J;Lecumberri MJ;Cruz JJ;.Phase II study of
capecitabine as palliative treatment for patients with recurrent and metastatic squamous head and neck cancer after previous
platinum-based treatment.British Journal of Cancer.2010;102(12):1687-1691
Mesia Nin R;Pastor Borgonon M;Cruz Hernandez JJ;Isla Casado D;.SEOM clinical guidelines for the treatment of head and neck
Moros MT;Ruidiaz M;Caballero A;Serrano E;Martinez V;Tres A;.Effects of an exercise training program on the quality of life of
women with breast cancer on chemotherapy.Rev Med Chile.2010;138(6):715-722
Rodriguez-Abreu D;Llanos Munoz M;Provencio Pulla M;Rueda Dominguez A;Isla Casado D;.SEOM clinical guidelines for the
treatment of follicular non-Hodgkin's lymphoma.Clin Transl Oncol.2010;12(11):760-764
Trigo Perez JM;Garrido Lopez P;Felip Font E;Isla Casado D;.SEOM clinical guidelines for the treatment of non-small-cell lung
cancer: An updated edition.Clin Transl Oncol.2010;12(11):735-741
Truong T;Hung RJ;Amos CI;Wu XF;Bickeboller H;Rosenberger A;Sauter W;Illig T;Wichmann HE;Risch A;Dienemann H;Kaaks
R;Yang P;Jiang RX;Wiencke JK;Wrensch M;Hansen H;Kelsey KT;Matsuo K;Tajima K;Schwartz AG;Wenzlaff A;Seow A;Ying
C;Staratschek-Jox A;Nurnberg P.Replication of Lung Cancer Susceptibility Loci at Chromosomes 15q25, 5p15, and 6p21: A
Pooled Analysis From the International Lung Cancer Consortium.Journal of the National Cancer Institute.2010;102(13):959-971
Quero Blanco C;Garcia Arroyo R;Provencio Pulla M;Rueda Dominguez A;Isla Casado D;.SEOM clinical guidelines for the
treatment of Hodgkin's lymphoma.Clin Transl Oncol.2010;12(11):753-759

3.1.42

Pediatría

Artero EG;Ortega FB;Espana-Romero V;Labayen I;Huybrechts I;Papadaki A;Rodriguez G;Mauro B;Widhalm K;Kersting M;Manios
Y;Molnar D;Moreno LA;Sjostrom M;Gottrand F;Castillo MJ;De Henauw S;.Longer Breastfeeding Is Associated with Increased
Lower Body Explosive Strength during Adolescence.Journal of Nutrition.2010;140(11):1989-1995
Casas

AA;Martinez

GR;Villagrasa

MPS;Fernandez-Espinar

JF;Cosculluela

PB;Hernandez

MPC;Bonel

MFS;Galindo

ABS;Martinez CP;.Differences Between Reference Charts of Weight in Children Up to the Age of 18 Months.Nutr
Hosp.2010;25(5):838-844
Moreno LA;Rodriguez G;Fleta J;Bueno-Lozano M;Lazaro A;Bueno G;.Trends of dietary habits in adolescents.Crit Rev Food
Sci.2010;50(2):106-112
Rodriguez G;Gallego S;Breidenassel C;Moreno LA;Gottrand F;.Is liver transaminases assessment an appropriate tool for the
screening of non-alcoholic fatty liver disease in at risk obese children and adolescents?.Nutr Hosp.2010;25(5):712-717
Torrelo A;Fernandez-Crehuet P;Del Prado E;Martes P;Hernandez-Martin A;De Diego V;Carapeto F;.Extensive Comedonal and
Cystic Acne in Patau Syndrome.Pediatr Dermatol.2010;27(2):199-200

25

3.1.43

Radiología, Medicina Nuclear y Diagnóstico por imagen

Andres A;Tardin L;Santapau A;Razola P;Prats E;Parra A;Rivas MA;Ruiz P;Alvarez R;Camara A;Banzo J;.Treatment with I-131 of
thyroid remnants in a patient with papillary thyroid carcinoma and end-stage chronic renal failure.Rev Esp Med
Nucl.2010;29(1):32-35
Banzo J;Ubieto MA;Prats E;Razola P;Tardin L;Andres A;Santapau A;Parra A;.F-18-FDG PET-CT in cytomegalovirus-induced
mononucleosis.Rev Esp Med Nucl.2010;29(6):304-307
Mellado X;Cruz S;Artacho JM;Canellas M;.Reducing the number of segments in unidirectional MLC segmentations.Phys Med
Biol.2010;55(3):N75-N85

3.1.44

Regenerativa

Simonetti S;Molina MA;Queralt C;de Aguirre I;Mayo C;Bertran-Alamillo J;Sanchez JJ;Gonzalez-Larriba JL;Jimenez U;Isla
D;Moran T;Viteri S;Camps C;Garcia-Campelo R;Massuti B;Benlloch S;Cajal SRY;Taron M;Rosell R;.Detection of EGFR mutations
with mutation-specific antibodies in stage IV non-small-cell lung cancer.Journal of Translational Medicine.2010;8

3.1.45

Rehabilitación

Care.2010;19(5):699-700

3.1.46

Respiratorio

Arilla MC;Ibarrola I;Brena S;Martinez A;Colas C;Asturias JA;.The Russian Thistle (Salsola kali) Pollen Major Allergen, Sal k 1, Can
Be Quantified in Allergenic Extracts and Airborne Pollen.Int Arch Allergy Imm.2010;152(4):319-326
Colas C;Cebrian-Perez JA;Muino-Blanco T;.Caffeine induces ram sperm hyperactivation independent of cAMP-dependent protein
kinase.Int J Androl.2010;33(1):E187-E197
Ibanez MD;Navarro A;Sanchez MC;Rondon C;Montoro J;Mateu V;Lluch-Bernal M;Fernandez-Parra B;Dordal MT;Davila I;Conde
J;Anton E;Colas C;Valero A;.Rhinitis and its Association With Asthma in Patients Under 14 Years of Age Treated in Allergy
Departments in Spain.Journal of Investigational Allergology and Clinical Immunology.2010;20(5):402-406
Otero R;Uresandi F;Jimenez D;Cabezudo MA;Oribe M;Nauffal D;Conget F;Rodriguez C;Cayuela A;.Home treatment in pulmonary
embolism.Thromb Res.2010;126(1):E1-E5
Valero A;Ferrer M;Baro E;Sastre J;Navarro AM;Marti-Guadano E;Davila I;del Cuvillo A;Colas C;Antepara I;Alonso J;Mola
O;Izquierdo I;Mullol J;.Discrimination between moderate and severe disease may be used in patients with either treated or
untreated allergic rhinitis.Allergy.2010;65(12):1609-1613

3.1.47

Reumatología

Naredo E;Batlle-Gualda E;Garcia-Vivar ML;Garcia-Aparicio AM;Fernandez-Sueiro JL;Fernandez-Prada M;Giner E;RodriguezGomez M;Pina MF;Medina-Luezas JA;Toyos FJ;Campos C;Gutierrez-Polo R;Ferrer MA;Martinez O;az-Torne C;Gonzalez
T;Campos S;Queiro R;Castano-Sanchez M. Power Doppler Ultrasonography Assessment of Entheses in Spondyloarthropathies:
Response to Therapy of Entheseal Abnormalities.Journal of Rheumatology.2010;37(10):2110-2117

3.1.48

Salud Mental

Braam AW;Beekman ATF;Dewey ME;Delespaul PAEG;Fichter M;Lobo A;Magnusson H;Peres K;Reischies FM;Roelands M;Saz
P;Schoevers RA;Skoog I;Copeland JRM;.Depression and parkinsonism in older Europeans: results from the EURODEP
concerted action.Int J Geriatr Psyc.2010;25(7):679-687
Campayo A;de Jonge P;Roy JF;Saz P;de la Camara C;Quintanilla MA;Marcos G;Santabarbara J;Lobo A;.Depressive Disorder
and Incident Diabetes Mellitus: The Effect of Characteristics of Depression.Am J Psychiat.2010;167(5):580-588
Gutierrez-Galve L;Wheeler-Kingshott CAM;Altmann DR;Price G;Chu EM;Leeson VC;Lobo A;Barker GJ;Barnes TRE;Joyce
EM;Ron

MA;.Changes

in

the

Frontotemporal

Cortex

and

Cognitive

Correlates

in

First-Episode

Psychosis.Biol

Psychiat.2010;68(1):51-60

26

Lobo E;Dufouil C;Marcos G;Quetglas B;Saz P;Guallar E;Lobo A;.Is There an Association Between Low-to-Moderate Alcohol
Consumption and Risk of Cognitive Decline?.Am J Epidemiol.2010;172(6):708-716
Ruiz-Lazaro PM;Comet MP;Calvo AI;Zapata M;Cebollada M;Trebol L;Lobo A;.Prevalence of eating disorders in early adolescent
students.Actas Esp Psiquiatri.2010;38(4):204-211
MC;Tolosa E;.Efficacy and safety of pallidal stimulation in primary dystonia: results of the Spanish multicentric study.Journal of
Neurology Neurosurgery and Psychiatry.2010;81(1):65-69

3.1.49

Salud Pública y Servicios Sanitarios

Aibar-Arregui MA;Matia-Sanz M;Pelay-Cacho R;Iguzquiza-Pellejero MJ;Martin-Fortea MP;Clavel-Conget L;Gomez-Del Valle
C;Ruiz-Ruiz FJ;Sierra-Bergua B;.Nephritic colic management in an emergency room of a referral hospital.An Sist Sanit
Navar.2010;33(2):145-15
Aibar MA;Laborda K;Conget F;Cornudella R;.Hypercoagulability state and endotelial injury in stable chronic obstructive pulmonary
disease patients.An Sist Sanit Navar.2010;33(1):43-50
Carpenter KL, Duevel MA, Lee PW et al (Aibar C in working group). .Measures of patient safety in developing and emerging
countries: a review of the literature.Qual Saf Health Care.2010;19:48-54
Care.2010;19(5):699-700
Guijarro PM;Andres JMA;Mira JJ;Perdiguero E;Aibar C;.Adverse events in hospitals: the patient's point of view.Qual Saf Health
Care.2010;19(2):144-147
Martinez RG;Ibanez AM;Gomez PC;Villanueva ACG;Bergareche IA;Jaime CG;.Abdominal Girth Utility as a Method of Metabolic
Syndrome Screening in People with Hypertension.Revista Espanola De Salud Publica.2010;84(2):215-222
Olivera S;De Esealante B;Morandeira A;Val-Carreres P;Castillo MC;Castiella T;.Partial jejunal volvulus due to a mesenteric cystic
lymphangioma.An Sist Sanit Navar.2010;33(3):323-326

Hospital Obispo Polanco
3.1.50

FI: 8,174

Cirugía

Martin-Hernandez C;Cebamanos-Celma J;Molina-Ros A;Ballester-Jimenez JJ;Ballester-Soleda J;.Regenerated Cartilage
Produced by Autogenous Periosteal Grafts: A Histologic and Mechanical Study in Rabbits Under the Influence of Continuous
Passive Motion. Arthroscopy-The journal of arthroscopic and related surgery. 2010;26(1):76-83

3.1.51
Oviedo

Enfermedades Infecciosas
AM;Formento

EA;Gil

MJC;Burgui

JAM;.Dengue

fever:

differential

diagnosis

of

fever

in

travelers.Emergencias.2010;22(3):203-205

3.1.52

Medicina Interna

Rodriguez A;Cipres L;Tofe S;Polavieja P;Reviriego J;.Clinical evaluation of combined therapy for type 2 diabetes.Curr Med Res
Opin.2010;26(5):1171-1183
Lopez SZ;Vicario JM;Lerin FJ;Fernandez A;Perez G;Fonseca C;.Epstein-Barr Virus Myocarditis as the First Symptom of Infectious
Mononucleosis.Internal Med.2010;49(6):569-571

3.1.53


Lazaro BE;Formento EA;.Emergency management of hurried obstetric labor and delivery.Emergencias.2010;22(2):140-143

27

3.1.54

Oncología


3.1.55

Regenerativa

Rodriguez A;Cipres L;Tofe S;Polavieja P;Reviriego J;.Clinical evaluation of combined therapy for type 2 diabetes.Curr Med Res
Opin.2010;26(5):1171-1183

3.1.56

Traumatología

Martin-Hernandez C;Cebamanos-Celma J;Molina-Ros A;Ballester-Jimenez JJ;Ballester-Soleda J;.Regenerated Cartilage
Produced by Autogenous Periosteal Grafts: A Histologic and Mechanical Study in Rabbits Under the Influence of Continuous
Passive Motion. Arthroscopy-The journal of arthroscopic and related surgery. 2010;26(1):76-83

Hospital Royo Villanova
3.1.57

FI: 35,003

Cardiovascular

Almagro P;Garcia FL;Cabrera FJ;Montero L;Morchon D;Diez J;Soriano JB;.Comorbidity and gender-related differences in patients
hospitalized for COPD. The ECCO study.Resp Med.2010;104(2):253-259

3.1.58

Ciencia y Tecnología de los alimentos

Gomez-Sanz

E;Torres

C;Lozano

C;Fernandez-Perez

R;Aspiroz

C;Ruiz-Larrea

F;Zarazaga

M;.Detection,

Molecular

Characterization, and Clonal Diversity of Methicillin-Resistant Staphylococcus aureus CC398 and CC97 in Spanish Slaughter Pigs
of Different Age Groups.Foodborne Pathogens and disease.2010;7(10):1269-1277

3.1.59

Cirugía

Garcia-Alvarez F;Al-Ghanem R;Garcia-Alvarez I;Lopez-Baisson A;Bernal M;.Risk factors for postoperative infections in patients
with hip fracture treated by means of Thompson arthroplasty.Arch Gerontol Geriat.2010;50(1):51-55

3.1.60

Digestivo

Abuli A;Bessa X;Gonzalez JR;Ruiz-Ponte C;Caceres A;Munoz J;Gonzalo V;Balaguer F;Fernandez-Rozadilla C;Gonzalez D;de
Castro L;Clofent J;Bujanda L;Cubiella J;Rene JM;Morillas JD;Lanas A;Rigau J;Garcia AM;Latorre M;Salo J;Banares FF;Arguello
L;Pena

E;Vilella.Susceptibility

Genetic

Variants

Associated

With

Colorectal

Cancer

Risk

Correlate

With

Cancer

Phenotype.Gastroenterology.2010;139(3):788-U129
Lucas MO;Peiro PS;Domingo JJS;.Irritable bowel syndrome immune hypothesis. Part one: the role of lymphocytes and mast
cells.Rev Esp Enferm Dig.2010;102(11):637-647
Lucas MO;Peiro PS;Domingo JJS;.Irritable bowel syndrome immune hypothesis. Part two: the role of cytokines.Rev Esp Enferm
Dig.2010;102(12):711-717

3.1.61


Aspiroz C;Gilaberte Y;Rezusta A;Boekhout T;Rubio MC;.Gentamycin inhibits the growth of Malassezia pachydermatis in
culture.Revista Iberoamericana De Micologia.2010;27(1):20-21
Tubau F;Linares J;Rodriguez MD;Cercenado E;Aldea MJ;Gonzalez-Romo F;Torroba L;Berdonces P;Plazas J;Aguilar L;Delgado
A;Garcia-Escribano N;.Susceptibility to tigecycline of isolates from samples collected in hospitalized patients with secondary
peritonitis undergoing surgery.Diagostic microbiology and infectious disease.2010;66(3).308-313

28

3.1.62

Medicina Interna

Almagro P;Garcia FL;Cabrera FJ;Montero L;Morchon D;Diez J;de la Iglesia F;Roca FB;Fernandez-Ruiz M;Castiella J;Zubillaga
E;Recio J;Soriano JB;.Study of the comorbidities in hospitalized patients due to decompensated chronic obstructive pulmonary
disease attended in the Internal Medicine Services. ECCO Study. Revista Clínica Española.2010;210(3):101-108

3.1.63

Microbiología

Tubau F;Linares J;Rodriguez MD;Cercenado E;Aldea MJ;Gonzalez-Romo F;Torroba L;Berdonces P;Plazas J;Aguilar L;Delgado
A;Garcia-Escribano N;.Susceptibility to tigecycline of isolates from samples collected in hospitalized patients with secondary
peritonitis undergoing surgery.Diagnostic microbiology and infectious disease.2010;66(3).308-313

3.1.64

Neurociencias

JA;Garcia-Gomara MJ;Artal-Roy J;.Comparative study of the effectiveness of topiramate and nadolol in the preventive treatment
of episodic migraine in independent series of patients. Revista de Neurologia.2010;50(9):513-519

3.1.65

Respiratorio

Almagro P;Garcia FL;Cabrera FJ;Montero L;Morchon D;Diez J;Soriano JB;.Comorbidity and gender-related differences in patients
hospitalized for COPD. The ECCO study.Resp Med.2010;104(2):253-259
Dominguez A;Izquierdo C;Salleras L;Ruiz L;Sousa D;Bayas JM;Nebot M;Varona W;Celorrio JM;Carratala J;.Effectiveness of the
pneumococcal polysaccharide vaccine in preventing pneumonia in the elderly.Eur Respir J.2010;36(3):608-614

3.1.66

Salud Mental

Arilla JA;Fernandez ME;Vinuales E;Lozano I;.Antipsychotic polypharmacy in a general hospital in-patient psychiatric unit.Revista
De Psiquiatria Y Salud Mental.2010;3(3):90-96

3.1.67

Salud Pública

Izquierdo C;Oviedo M;Ruiz L;Sintes X;Vera I;Nebot M;Bayas JM;Carratala J;Varona W;Sousa D;Celorrio JM;Salleras
L;Dominguez A;.Influence of socioeconomic status on community-acquired pneumonia outcomes in elderly patients requiring
hospitalization: a multicenter observational study.BMC Public Health.2010;10

Hospital San Jorge
3.1.68

FI: 149,954

Biofísica

Gonzalez S;Gilaberte Y;Philips N;.Mechanistic insights in the use of a Polypodium leucotomos extract as an oral and topical
photoprotective agent.Photoch Photobio Sci.2010;9(4):559-563

3.1.69

Bioquímica y Biología molecular


3.1.70

Cardiovascular

Puzo J;Alfonso P;Irun P;Gervas J;Pocovi M;Giraldo P;.Changes in the atherogenic profile of patients with type 1 Gaucher disease
after miglustat therapy.Atherosclerosis.2010;209(2):515-519

29

Sole-Violan J;de Castro FR;Garcia-Laorden MI;Blanquer J;Aspa J;Borderias L;Briones ML;Rajas O;Carrondo IML;Marcos-Ramos
JA;Aguero JMF;Garcia-Saavedra A;Fiuza MD;Caballero-Hidalgo A;Rodriguez-Gallego C;.Genetic variability in the severity and
outcome of community-acquired pneumonia.Respiratory Medicine.2010;104(3):440-447

3.1.71

Dermatología

Gilaberte Y;Frias MP;Perez-Lorenz JB;.Chondrodermatitis Nodularis Helicis Successfully Treated With Photodynamic
Therapy.Arch Dermatol.2010;146(10):1080-1082
Gonzalez S;Philips N;Gilaberte Y;.Photoprotection: update in UV-filter molecules, the 'new wave' of sunscreens.Giornale Italiano
Di Dermatologia E Venereologia.2010;145(4):515-523

3.1.72

Genética

Kiemeney LA;Sulem P;Besenbacher S;Vermeulen SH;Sigurdsson A;Thorleifsson G;Gudbjartsson DF;Stacey SN;Gudmundsson
J;Kostic J;Masson G;Bjarnason H;Palsson ST;Skarphedinsson OB;Gudjonsson SA;Witjes JA;Grotenhuis AJ;Verhaegh
GW;Bishop DT;Sak SC;Choudhury A;. A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer. Nature
Genetics.2010;42(5):415-U67

3.1.73

Hematología

Silverman LB;Supko JG;Stevenson KE;Woodward C;Vrooman LM;Neuberg DS;Asselin BL;Athale UH;Clavell L;Cole PD;Kelly
KM;Laverdiere C;Michon B;Schorin M;Schwartz CL;O'Brien JE;Cohen HJ;Sallan SE;.Intravenous PEG-asparaginase during
remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia.Blood.2010;115(13):13511353

3.1.74


Peralta PSO;Vazquez-Torres MC;Latorre-Fandos E;Mairal-Claver P;Cortina-Solano P;Puy-Azon A;Sancho BA;Leitmeyer
K;Lucientes-Curdi J;Sierra-Moros MJ;.First autochthonous malaria case due to Plasmodium vivax since eradication, Spain,
October 2010.Eurosurveillance. 2010;15(41):2-4

3.1.75

Medicina Interna

Garrido A;Iborra MI;Saperas E;de Sousa M;.Prevalence of rebleeding from peptic ulcer in patients treated with proton pump
inhibitors.Med Clin-barcelona.2010;134(13):577-582

3.1.76

Neurociencias

Gazulla J;Benavente I;Lopez-Fraile IP;Tordesillas C;Modrego P;Alonso I;Pinto-Basto J;.Sensory neuronopathy in ataxia with
oculomotor apraxia type 2.J Neurol Sci.2010;298(01-feb):118-120
episodic migraine in independent series of patients.Revista de neurología.2010;50(9):513-519
Revilla

I;Segura

LY;Arrillaga AGP;Suarez

PB;.Attitudes

of the

family toward

the mentally

ill

patient.Actas

Esp

Psiquiatri.2010;38(1):57-64

30

3.1.77

Respiratorio

Borderias L;Morell F;Vera J;Briz H;Munoz X;Cruz MJ;.Starling-Induced Hypersensitivity Pneumonitis: Minimal but Persistent
Antigen Exposure.Arch Bronconeumol.2010;46(11):607-609
Portillo K;Santos S;Madrigal I;Blanco I;Pare C;Borderias L;Peinado VI;Roca J;Mila M;Barbera JA;.Study of the BMPR2 Gene in
Patients with Pulmonary Arterial Hypertension.Arch Bronconeumol.2010;46(3):129-134
Sole-Violan J;de Castro FR;Garcia-Laorden MI;Blanquer J;Aspa J;Borderias L;Briones ML;Rajas O;Carrondo IML;Marcos-Ramos
JA;Aguero JMF;Garcia-Saavedra A;Fiuza MD;Caballero-Hidalgo A;Rodriguez-Gallego C;.Genetic variability in the severity and
outcome of community-acquired pneumonia.Respiratory Medicine.2010;104(3):440-447
Soriano JB;Miravitlles M;Borderias L;Duran-Tauleria E;Rio FG;Martinez J;Montemayor T;Munoz L;Pineiro L;Sanchez G;Serra
J;Soler-Cataluna JJ;Torres A;Viejo JL;Sobradillo-Pena V;Ancochea J;.Geographical Variations in the Prevalence of COPD in
Spain: Relationship to Smoking, Death Rates and other Determining Factors.Archivos de Bronconeumología.2010;46(10):522-530

3.1.78

Reumatología

Garcia-Doval I;Perez-Zafrilla B;Descalzo MA;Rosello R;Hernandez MV;Gomez-Reino JJ;Carmona L;.Incidence and risk of
hospitalisation due to shingles and chickenpox in patients with rheumatic diseases treated with TNF antagonists.Ann Rheum
Dis.2010;69(10):17

3.1.79
Revilla

Salud Mental
I;Segura

LY;Arrillaga AGP;Suarez

PB;.Attitudes

of the

family toward

the mentally

ill

patient.Actas

Esp

Psiquiatri.2010;38(1):57-64

3.1.80

Salud Pública

Fajo-Pascual M;Godoy P;Ferrero-Cancer M;Wymore K;.Case-control study of risk factors for sporadic Campylobacter infections in
northeastern Spain.Eur J Public Health.2010;20(4):443-448

Hospital Universitario Miguel Servet
3.1.81

FI: 433,859

Alergología

Ibero M;Bone J;Martin B;Martinez J;.Evaluation of an extensively hydrolysed casein formula (Damira 2000 (R)) in children with
allergy to cow's milk proteins.Allergol Immunopath.2010;38(2):60-68

3.1.82

Anatomía Patológica

Pagni F;Zarate AF;Urbanski SJ;.Necrotizing Sialometaplasia of Bronchial Mucosa.Int J Surg Pathol.2010;18(1):64-65
Matarraz S;Lopez A;Barrena S;Fernandez C;Jensen E;Flores-Montero J;Rasillo A;Sayagues JM;Sanchez ML;Barcena
P;Hernandez-Rivas JM;Salvador C;Fernandez-Mosteirin N;Giralt M;Perdiguer L;Laranjeira P;Paiva A;Orfao A;.Bone Marrow Cells
from Myelodysplastic Syndromes Show Altered Immunophenotypic Profiles That May Contribute to the Diagnosis and Prognostic
Stratification of the Disease: a Pilot Study on A Series of 56 Patients.Cytometry partB-clinical cytometry.2010;78B(3):154-168

3.1.83

Atención Primaria

Fayed N;Garcia-Campayo J;Magallon R;ndres-Bergareche H;Luciano JV;Andres E;Beltran J;.Localized H-1-NMR spectroscopy in
patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and Nacetylaspartate.Arthritis Research & Therapy.2010;12(4):

3.1.84

Biología

Fernandez-Vizarra E;Ferrin G;Perez-Martos A;Fernandez-Silva P;Zeviani M;Enriquez JA;.Isolation of mitochondria for
biogenetical studies: An update.Mitochondrion.2010;10(3):253-262

31

3.1.85

Bioquímica y biología molecular

Martin P;Pardo J;Schill N;Jockel L;Berg M;Froelich CJ;Wallich R;Simon MM;.Granzyme B-induced and caspase 3-dependent
cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics.J Biol Chem.2010;285(24):18918-18927

3.1.86

Biotecnología

Lavilla M;Marzo I;de Luis R;Perez MD;Calvo M;Sanchez L;.Detection of Clostridium tyrobutyricum spores using polyclonal
antibodies and flow cytometry.J Appl Microbiol.2010;108(2):488-498

3.1.87

Cardiovascular

Burillo E;Andres EM;Mateo-Gallego R;Fiddyment S;Jarauta E;Cenarro A;Civeira F;.High-density lipoprotein cholesterol increase
and non-cardiovascular mortality: a meta-analysis.Heart.2010;96(17):1345-1351
Cabre A;Lazaro I;Cofan M;Jarauta E;Plana N;Garcia-Otin AL;Ascaso JF;Ferre R;Civeira F;Ros E;Masana L;.FABP4 plasma levels
are increased in familial combined hyperlipidemia.J Lipid Res.2010;51(5):1173-1178
Hollak CEM;vom Dahl S;Aerts JMFG;Belmatoug N;Bembi B;Cohen Y;Collin-Histed T;Deegan P;van Dussen L;Giraldo P;Mengel
E;Michelakakis H;Manuel J;Hrebicek M;Parini R;Reinke J;di Rocco M;Pocovi M;Miranda MCS;Tylki-Szymanska A;Zimran A;Cox
TM;.Force Majeure: Therapeutic measures in response to restricted supply of imiglucerase (Cerezyme) for patients with Gaucher
disease.Blood Cells Molecules and Diseases.2010;44(1):41-47
Junyent M;Gilabert R;Jarauta E;Nunez I;Cofan M;Civeira F;Pocovi M;Mallen M;Zambon D;Almagro F;Vega J;Tejedor D;Ros
E;.Impact of low-density lipoprotein receptor mutational class on carotid atherosclerosis in patients with familial
hypercholesterolemia.Atherosclerosis.2010;208(2):437-441
Martin B;Solanas-Barca M;Garcia-Otin AL;Pampin S;Cofan M;Ros E;Rodriguez-Rey JC;Pocovi M;Civeira F;.An NPC1L1 gene
promoter variant is associated with autosomal dominant hypercholesterolemia.Nutr Metab Cardiovas.2010;20(4):236-242
Mateo-Gallego R;Calmarza P;Jarauta E;Burillo E;Cenarro A;Civeira F;.Serum ferritin is a major determinant of lipid phenotype in
familial combined hyperlipidemia and familial hypertriglyceridemia.Metabolism.2010;59(2):154-158
Mateo-Gallego R;Solanas-Barca M;Burillo E;Cenarro A;Marques-Lopes I;Civeira F;.Iron deposits and dietary patterns in familial
combined hyperlipidemia and familial hypertriglyceridemia.J Physiol Biochem.2010;66(3):229-236
Robles NR;Ocon J;Gomez CF;Manjon M;Pastor L;Herrera J;Villatoro J;Calls J;Torrijos J;Rodriguez VI;Rodriguez MMA;Mendez
ML;Morey A;Martinez FI;Marco J;Liebana A;Rincon B;Tornero F;.Lercanidipine in patients with chronic renal failure: the ZAFRA
Study.Cardiovascular Therapy and Prevention.2010;9(4):81-87
Sala-Vila A;Cofan M;Perez-Heras A;Nunez I;Gilabert R;Junyent M;Mateo-Gallego R;Cenarro A;Civeira F;Ros E;.Fatty acids in
serum phospholipids and carotid intima-media thickness in Spanish subjects with primary dyslipidemia.Am J Clin
Nutr.2010;92(1):186-193
Tejedor MT;Cenarro A;Tejedor D;Stef M;Mateo-Gallego R;de Castro I;Garcia-Otin AL;Monteagudo LV;Civeira F;Pocovi
M;.Haplotype analyses, mechanism and evolution of common double mutants in the human LDL receptor gene.Mol Genet
Genomics.2010;283(6):565-574
Zambon D;Quintana M;Mata P;Alonso R;Benavent J;Cruz-Sanchez F;Gich J;Pocovi M;Civeira F;Capurro S;Bachman
D;Sambamurti K;Nicholas J;Pappolla MA;.Higher Incidence of Mild Cognitive Impairment in Familial Hypercholesterolemia.Am J
Med.2010;123(3):267-274

3.1.88

Cirugía

Crespo-Leiro MG;Delgado JF;Paniagua MJ;de Prada JAV;Fernandez-Yanez J;Almenar L;az-Molina B;Roig E;Arizon JM;onsoPulpon L;Garrido IP;Sanz ML;de la Fuente L;Mirabet S;Manito N;Muniz J;.Prevalence and severity of renal dysfunction among
1062 heart transplant patients according to criteria based on serum creatinine and estimated glomerular filtration rate: results from
the CAPRI study.Clinical Transplantation.2010;24(4):E88-E93

32

Delgado JF;Crespo-Leiro MG;Gomez-Sanchez MA;Paniagua MJ;Gonzalez-Vilchez F;de Prada JAV;Fernandez-Yanez J;Pascual
D;Almenar L;Martinez-Dolz L;Diaz B;Roig E;Segovia J;Arizon JM;Garrido I;Blasco T;Lopez J;Brossa V;Manito N;Muniz J;.Risk
factors associated with moderate-to-severe renal dysfunction among heart transplant patients: results from the CAPRI
study.Clinical Transplantation.2010;24(5):E194-E200.
Gutierrez-Dalmau A;Revuelta I;Ferrer B;Mascaro JM;Oppenheimer F;Albanell J;Campistol JM;.Distinct Immunohistochemical
Phenotype

of

Nonmelanoma

Skin

Cancers

Between

Renal

Transplant

and

Immunocompetent

Populations.Transplantation.2010;90(9):986-992
Pagni F;Zarate AF;Urbanski SJ;.Necrotizing Sialometaplasia of Bronchial Mucosa.Int J Surg Pathol.2010;18(1):64-65

3.1.89

Digestivo

Fernandez-Rodriguez CM;Alonso S;Martinez SM;Forns X;Sanchez-Tapias JM;Rincon D;Rodriguez-Caravaca G;Barcena R;Serra
MA;Romero-Gomez M;Fernandez I;Garcia-Samaniego J;Fuente J;Sola R;Moreno-Otero R;Planas R;.Peginterferon Plus Ribavirin
and Sustained Virological Response in HCV-Related Cirrhosis: Outcomes and Factors Predicting Response.American Journal of
Gastroenterology.2010;105(10):2164-2172
Mearin F;Balboa A;Castells A;Dominguez JE;Esteve M;Garcia-Erce JA;Gisbert JP;Gomollon F;Panes J;Ponce J;.Iron deficiency
anemia and use of intravenous iron in digestive disease.Gastroenterologia Y Hepatologia.2010;33(8):605-613
Uribarrena-Amezaga R;Ortego J;Fuentes J;Raventos N;Parra P;Uribarrena-Echevarria R;.Prognostic value of lymph node
micrometastases in patients with colorectal cancer in Dukes stages A and B (T1-T4, N0, M0).Rev Esp Enferm
Dig.2010;102(3):176-181

3.1.90

Endocrinología y metabolismo

Altirriba J;Gasa R;Casas S;Ramirez-Bajo MJ;Ros S;Gutierrez-Dalmau A;de Villa MCR;Barbera A;Gomis R;.The role of
transmembrane

protein

27

(TMEM27)

in

islet

physiology

and

its

potential

use

as

a

beta

cell

mass

biomarker.Diabetologia.2010;53(7):1406-1414
Luque-Ramirez M;Portoles GR;Varela C;Albero R;Halperin I;Moreiro J;Soto A;Casamitjana R;.The Efficacy of Octreotide LAR as
Firstline Therapy for Patients with Newly Diagnosed Acromegaly is Independent of Tumor Extension: Predictive Factors of Tumor
and Biochemical Response.Hormone and metabolic research.2010;42(1):38-44.

3.1.91

Enfermedades infecciosas

Betran A;Villuendas MC;Rezusta A;Moles B;Rubio MC;Revillo MJ;Boiron P;Bello S;Rodriguez-Nava V;.Cavitary Pneumonia
Caused by Nocardia Otitidiscaviarum.Braz J Microbiol.2010;41(2):329-332
Najafzadeh MJ;Rezusta A;Cameo MI;Zubiri ML;Yus MC;Badali H;Revillo MJ;De Hoog GS;.Successful treatment of
chromoblastomycosis of 36 years duration caused by Fonsecaea monophora.Med Mycol.2010;48(2):390-393
Roc ML;Palacian MP;Lomba E;Monforte ML;Rebaje V;Pinilla MJR;.Serologic diagnosis of congenital toxoplasmosis.Enferm Infec
Micr Cl.2010;28(8):517-519

3.1.92

Genética

Fernandez-Vizarra E;Ferrin G;Perez-Martos A;Fernandez-Silva P;Zeviani M;Enriquez JA;.Isolation of mitochondria for
biogenetical studies: An update.Mitochondrion.2010;10(3):253-262

3.1.93

Hematología

Alvarez-Larran A;Cervantes F;Pereira A;rellano-Rodrigo E;Perez-Andreu V;Hernandez-Boluda JC;Ayats R;Salvador C;Muntanola
A;Bellosillo B;Vicente V;Hernandez-Nieto L;Burgaleta C;Xicoy B;Besses C;.Observation versus antiplatelet therapy as primary
prophylaxis for thrombosis in low-risk essential thrombocythemia.Blood.2010;116(8):1205-1210

33

Biegstraaten M;Mengel E;Marodi L;Petakov M;Niederau C;Giraldo P;Hughes D;Mrsic M;Mehta A;Hollak CEM;van Schaik
IN;.Peripheral neuropathy in adult type 1 Gaucher disease: a 2-year prospective observational study.Brain.2010;133:2909-2919
Chillon MC;Santamaria C;Garcia-Sanz R;Balanzategui A;Sarasquete ME;Alcoceba M;Marin L;Caballero MD;Vidriales MB;Ramos
F;Bernal T;az-Mediavilla J;de Coca AG;Penarrubia MJ;Queizan JA;Giraldo P;San Miguel JF;Gonzalez M;.Long FLT3 internal
tandem duplications and reduced PML-RAR alpha expression at diagnosis characterize a high-risk subgroup of acute
promyelocytic leukemia patients.Hematologica-The hematology journal.2010;95(5):745-751
Hollak CEM;vom Dahl S;Aerts JMFG;Belmatoug N;Bembi B;Cohen Y;Collin-Histed T;Deegan P;van Dussen L;Giraldo P;Mengel
E;Michelakakis H;Manuel J;Hrebicek M;Parini R;Reinke J;di Rocco M;Pocovi M;Miranda MCS;Tylki-Szymanska A;Zimran A;Cox
TM;.Force Majeure: Therapeutic measures in response to restricted supply of imiglucerase (Cerezyme) for patients with Gaucher
disease.Blood cells molecules and diseases.2010;44(1):41-47
Marcos-Gragera R;Cervantes-Amat M;Vicente ML;de Sanjose S;Guallar E;Godoy C;Calvo C;Giraldo P;Sant M;Peris-Bonet
R;Martos MC;.Population-based incidence of childhood leukaemias and lymphomas in Spain (1993-2002).Eur J Cancer
Prev.2010;19(4):247-255
Matarraz S;Lopez A;Barrena S;Fernandez C;Jensen E;Flores-Montero J;Rasillo A;Sayagues JM;Sanchez ML;Barcena
P;Hernandez-Rivas JM;Salvador C;Fernandez-Mosteirin N;Giralt M;Perdiguer L;Laranjeira P;Paiva A;Orfao A;.Bone Marrow Cells
from Myelodysplastic Syndromes Show Altered Immunophenotypic Profiles That May Contribute to the Diagnosis and Prognostic
Stratification of the Disease: a Pilot Study on A Series of 56 Patients.Cytometry part B-clinical cytometry.2010;78(3):154-168
Oriol A;Vives S;Hernandez-Rivas JM;Tormo M;Heras I;Rivas C;Bethencourt C;Moscardo F;Bueno J;Grande C;del Potro
E;Guardia R;Brunet S;Bergua J;Bernal T;Moreno MJ;Calvo C;Bastida P;Feliu E;Ribera JM;.Outcome after relapse of acute
lymphoblastic leukemia in adult patients included in four consecutive risk-adapted trials by the PETHEMA Study
Group.Haematologica-the hematology journal.2010;95(4):589-596
Perez Delgado R;Lafuente Hidalgo M;Lopez Pison J;Sebastian Torres B;Torres Claveras S;Garcia Jimenez MC;Baldellou
Vazquez

A;Pena

Segura

JL;.Epilepsy

onset

between

one

month

and

three

months

of

life:

Our

11

years

experience.Neurologia.2010;25(2):90-95
Pie J;Gil-Rodriguez MC;Ciero M;Lopez-Vinas E;Ribate MP;Arnedo M;Deardorff MA;Puisac B;Legarreta J;de Karam JC;Rubio
E;Bueno I;Baldellou A;Calvo MT;Casals N;Olivares JL;Losada A;Hegardt FG;Krantz ID;Gomez-Puertas P;Ramos FJ;.Mutations
and Variants in the Cohesion Factor Genes NIPBL, SMC1A, and SMC3 in a Cohort of 30 Unrelated Patients With Cornelia de
Lange Syndrome.American Journal of medical genetics.2010;152(4):924-929
Santamaria C;Chillon MC;Garcia-Sanz R;Perez C;Caballero MD;Mateos MV;Ramos F;de Coca AG;Alonso JM;Giraldo P;Bernal
T;Queizan JA;Rodriguez JN;Puig N;Balanzategui A;Sarasquete ME;Alcoceba M;az-Mediavilla J;San Miguel J;Gonzalez
M;.BAALC is an important predictor of refractoriness to chemotherapy and poor survival in intermediate-risk acute myeloid
leukemia (AML).Annals of hematology.2010,89(5):453-458
Urreizti R;Moya-Garcia AA;Pino-Angeles A;Cozar M;Langkilde A;Fanhoe U;Esteves C;Arribas J;Vilaseca MA;Perez-Duenas
B;Pineda M;Gonzalez V;Artuch R;Baldellou A;Vilarinho L;Fowler B;Ribes A;Sanchez-Jimenez F;Grinberg D;Balcells S;.Molecular
characterization of five patients with homocystinuria due to severe methylenetetrahydrofolate reductase deficiency.Clinical
Genetics.2010;78(5):441-448

3.1.94

Ingeniería Biomédica

E. Gil, J.M. Vergara, and P. Laguna.Pulse Transit Time Variability versus Heart Rate Variability during Decreases in the Amplitude
fluctuations of Photoplethysmography signal.International Journal Of Bioelectromagnetism .2010;12(3):95-101
Gracia L;Ibarz E;Puertolas S;Cegonino J;Lopez-Prats F;Panisello JJ;Herrera A;.Study of bone remodeling of two models of
femoral cementless stems by means of DEXA and finite elements.Biomed Eng Online.2010;9
Puertolas S;Perez-Garcia JM;Gracia L;Cegonino J;Ibarz E;Puertolas JA;Herrera A;.Design of splints based on the NiTi alloy for
the correction of joint deformities in the fingers.Biomed Eng Online.2010;9

34

3.1.95

Inmunología

Gutierrez-Dalmau A;Revuelta I;Ferrer B;Mascaro JM;Oppenheimer F;Albanell J;Campistol JM;.Distinct Immunohistochemical
Phenotype

of

Nonmelanoma

Skin

Cancers

Between

Renal

Transplant

and

Immunocompetent

Populations.Transplantation.2010;90(9):986-992
Ibero M;Bone J;Martin B;Martinez J;.Evaluation of an extensively hydrolysed casein formula (Damira 2000 (R)) in children with
allergy to cow's milk proteins.Allergol Immunopath.2010;38(2):60-68

3.1.96

Medicina Interna

Ambroj CM;Osuna JGG;Lezcano JSR;Cebollero IC;Gracia MCF;Peralta LJP;.Acute reperfusion therapy in elderly women with
acute

myocardial

infarction

with

ST-segment

elevation:

efficacy

in

the

reduction

of

their

mortality.Med

Clin-

barcelona.2010;134(8):333-339
Duran-Cantolla J;Aizpuru F;Montserrat JM;Ballester E;Teran-Santos J;Aguirregomoscorta JI;Gonzalez M;Lloberes P;Masa JF;De
la Pena M;Carrizo S;Mayos M;Barbe F;.Continuous positive airway pressure as treatment for systemic hypertension in people with
obstructive sleep apnoea: randomised controlled trial.British Medical Journal.2010;341
Mendoza MA;Ruiz FJM;Lasfuentes PC;Aznarez HN;Espanol AP;Hernandez MJR;.Tumour necrosis factor alpha antagonists in
established rheumatoid arthritis: Effectiveness comparative study.Med Clin-barcelona.2010;134(15):665-670

3.1.97

Microbiología

Lavilla M;Marzo I;de Luis R;Perez MD;Calvo M;Sanchez L;.Detection of Clostridium tyrobutyricum spores using polyclonal
antibodies and flow cytometry.J Appl Microbiol.2010;108(2):488-498
Roc ML;Palacian MP;Lomba E;Monforte ML;Rebaje V;Pinilla MJR;.Serologic diagnosis of congenital toxoplasmosis.Enferm Infec
Micr Cl.2010;28(8):517-519

3.1.98

Neurociencias

Almarcegui C;Dolz I;Pueyo V;Garcia E;Fernandez FJ;Martin J;Ara JR;Honrubia F;.Correlation between functional and structural
assessments of the optic nerve and retina in multiple sclerosis patients.Neurophysiol Clin.2010;40(3):129-135
Garcia-Martin E;Pueyo V;Martin J;Almarcegui C;Ara JR;Dolz I;Honrubia FM;Fernandez FJ;.Progressive changes in the retinal
nerve fiber layer in patients with multiple sclerosis.Eur J Ophthalmol.2010;20(1):167-173
Gazulla J;Benavente I;Lopez-Fraile IP;Tordesillas C;Modrego P;Alonso I;Pinto-Basto J;.Sensory neuronopathy in ataxia with
oculomotor apraxia type 2.J Neurol Sci.2010;298(01-feb):118-120
episodic migraine in independent series of patients.Revista de neurología.2010;50(9):513-519
Hernandez JMDT;Alfonso F;Gimeno F;Diarte JA;Lopez-Palop R;de Prado AP;Rivero F;Sanchis J;Larman M;Diaz JF;Elizaga
J;Moreiras JM;Jaume AG;Hernandez JM;Mauri J;Recalde AS;Bullones JA;Rumoroso JR;del Blanco BG;Baz JA;Bosa F;Botas
J;Hernandez F;.Thrombosis of Second-Generation Drug-Eluting Stents in Real Practice Results From the Multicenter Spanish
Registry ESTROFA-2 (Estudio Espanol Sobre Trombosis de Stents Farmacoactivos de Segunda Generacion-2). JaccCardiovascular interventions.2010;3(9):911-919
Lull N;Noe E;Lull JJ;Garcia-Panach J;Garcia-Marti G;Chirivella J;Ferri J;Sopena R;de La Cueva L;Robles M;.Thalamic metabolism
and neurological outcome after traumatic brain injury. A voxel-based morphometric FDG-PET study.Neurologia.2010;25(3):174180
Modrego PJ;.Depression in Alzheimer's Disease. Pathophysiology, Diagnosis, and Treatment.J Alzheimers Dis.2010;21(4):10771087

35

Pascual-Gomez J;Gracia-Naya M;Leira R;Mateos V;varo-Gonzalez LC;Hernando I;Oterino A;Iglesias-Diez F;Caminero A;GarciaMonco JC;Forcea N;Guerrero-Peral AL;Bueno V;Santos-Garcia D;Perez C;Blanco M;Pego-Reigosa R;Rodriguez R;MedererHengstl S;Pato-Pato A;. Zonisamide in the preventive treatment of refractory migraine.Revista de neurología.2010;50(3):129-132
Pueyo V;Ara JR;Almarcegui C;Martin J;Guerri N;Garcia E;Pablo LE;Honrubia FM;Fernandez FJ;.Sub-clinical atrophy of the retinal
nerve fibre layer in multiple sclerosis.Acta Ophthalmol.2010;88(7):748-752
Sanchez-Carteyron A;Alarcia R;Ara JR;Martin J;.Posterior reversible encephalopathy syndrome after rituximab infusion in
neuromyelitis optica.Neurology.2010;74(18):1471-1473

3.1.99


Medel JM;Mateo SC;Conde CR;Esque ACC;Mitchell MJR;.Spontaneous uterine rupture caused by placenta percreta at 18 weeks'
gestation after in vitro fertilization.J Obstet Gynaecol Re.2010;36(1):170-173

3.1.100 Oftalmología
Almarcegui C;Dolz I;Pueyo V;Garcia E;Fernandez FJ;Martin J;Ara JR;Honrubia F;.Correlation between functional and structural
assessments of the optic nerve and retina in multiple sclerosis patients.Neurophysiol Clin.2010;40(3):129-135
Cuenca N;Pinilla I;Fernandez-Sanchez L;Salinas-Navarro M;arcon-Martinez L;viles-Trigueros M;de la Villa P;de Imperial
JM;Villegas-Perez MP;Vidal-Sanz M;.Changes in the inner and outer retinal layers after acute increase of the intraocular pressure
in adult albino Swiss mice.Experimental eye research.2010;91(2):273-285
Fernandez-Barrientos Y;Garcia-Feijoo J;Martinez-de-la-Casa J;Pablo LE;Fernandez-Perez C;Sanchez JG;.Fluorophotometric
Study of the Effect of the Glaukos Trabecular Microbypass Stent on Aqueous Humor Dynamics.Invest Ophth Vis
Sci.2010;51(7):3327-3332
Figus M;Fogagnolo P;Lazzeri S;Capizzi F;Romagnoli M;Canovetti A;Iester M;Ferreras A;Rossetti L;Nardi M;.Treatment of allergic
conjunctivitis: results of a 1-month, single-masked randomized study.Eur J Ophthalmol.2010;20(5):811-818
Fogagnolo P;Capizzi F;Orzalesi N;Figus M;Ferreras A;Rossetti L;.Can Mean Central Corneal Thickness and Its 24-hour
Fluctuation Influence Fluctuation of Intraocular Pressure?.J Glaucoma.2010;19(6):418-423
Fogagnolo P;Figus M;Frezzotti P;Iester M;Oddone F;Zeppieri M;Ferreras A;Brusini P;Rossetti L;Orzalesi N;.Test-retest variability
of intraocular pressure and ocular pulse amplitude for dynamic contour tonometry: a multicentre study.Brit J Ophthalmol.2010;9
Garcia-Martin E;Pueyo V;Martin J;Almarcegui C;Ara JR;Dolz I;Honrubia FM;Fernandez FJ;.Progressive changes in the retinal
nerve fiber layer in patients with multiple sclerosis.Eur J Ophthalmol.2010;20(1):167-173
Garcia-Martin E;Idoipe M;Gil LM;Pueyo V;Alfaro J;Pablo LE;Zubiri ML;Fernandez J;.Efficacy and Tolerability of Imiquimod 5%
Cream to Treat Periocular Basal Cell Carcinomas.J Ocul Pharmacol Th.2010;26(4):373-379
Julvez LP;Sanchez JBD;Feijoo JG;Rubio-Terres C;.Methodologic Quality of Studies on Prognostic Factors for Primary Openangle Glaucoma Progression Measured by Visual Field Deterioration.J Glaucoma.2010;19(9):587-591
Pablo LE;Ferreras A;Pajarin AB;Fogagnolo P;.Diagnostic ability of a linear discriminant function for optic nerve head parameters
measured with optical coherence tomography for perimetric glaucoma.Eye.2010;24(6):1051-1057
Pablo LE;Ferreras A;Fogagnolo P;Figus M;Pajarin AB;.Optic nerve head changes in early glaucoma: a comparison between
stereophotography and Heidelberg retina tomography.Eye.2010;24(1):123-130
Pablo LE;Larrosa JM;Polo V;Ferreras A;Alias EG;Honrubia FM;.Performance of GDx and HRT in the Finnish Evidence-Based
Guideline for Open-Angle Glaucoma.Eye.2010;24(2):297-303
Pueyo V;Ara JR;Almarcegui C;Martin J;Guerri N;Garcia E;Pablo LE;Honrubia FM;Fernandez FJ;.Sub-clinical atrophy of the retinal
nerve fibre layer in multiple sclerosis.Acta Ophthalmol.2010;88(7):748-752
Ruiz MA;Pardo A;de la Casa JMM;Polo V;Esquiro J;Soto J;.Development of a Specific Questionnaire Measuring Patient
Satisfaction with Glaucoma Treatment: Glausat.Ophthal Epidemiol.2010;17(3):131-143
Sanchez-Cano A;Pablo LE;Larrosa JM;Polo V;.The Effect of Phacoemulsification Cataract Surgery on Polarimetry and
Tomography Measurements for Glaucoma Diagnosis.J Glaucoma.2010;19(7):468-474

36

3.1.101 Oncología
Anton A;Lluch A;Casado A;Provencio M;Munoz M;Lao J;Bermejo B;Paules AB;Gayo J;Martin M;.Phase I Study of Oral
Vinorelbine and Capecitabine in Patients with Metastatic Breast Cancer.Anticancer Res.2010;30(6):2255-2261
Artal CA;Domine GM;Font PA;Garcia CR;Cobo DM;Isla CD;.SEOM clinical guidelines for the treatment of small-cell lung
Bellmunt J;Maroto-Rey P;Trigo JM;Carles J;Guillem V;Lopez-Martin JA;nton-Torres A;Urruticoechea L;.A phase II trial of first-line
sorafenib in patients with metastatic renal cell carcinoma unwilling to receive or with early intolerance to immunotherapy: SOGUG
Study 06-01.Clinical&translational oncology.2010;12(7):503-508
Fernandez-Martos C;Pericay C;Aparicio J;Salud A;Safont M;Massuti B;Vera R;Escudero P;Maurel J;Marcuello E;Mengual
JL;Saigi E;Estevan R;Mira M;Polo S;Hernandez A;Gallen M;Arias F;Serra J;Alonso V;.Phase II, Randomized Study of
Concomitant Chemoradiotherapy Followed by Surgery and Adjuvant Capecitabine Plus Oxaliplatin (CAPOX) Compared With
Induction CAPOX Followed by Concomitant Chemoradiotherapy and Surgery in Magnetic Resonance Imaging-Defined, Locally
Advanced Rectal Cancer: Grupo Cancer de Recto 3 Study.Journal of clinical oncology.2010;28(5):859-865
Garcia-Carbonero R;Capdevila J;Crespo-Herrero G;az-Perez JA;del Prado MPM;Orduna VA;Sevilla-Garcia I;Villabona-Artero
C;Beguiristain-Gomez A;Llanos-Munoz M;Marazuela M;varez-Escola C;Castellano D;Vilar E;Jimenez-Fonseca P;Teule A;SastreValera J;Incidence, patterns of care and prognostic factors for outcome of gastroenteropancreatic neuroendocrine tumors (GEPNETs): results from the National Cancer Registry of Spain (RGETNE).Annals of oncology.2010;21(9):1794-1803
Garcia-Carbonero R;Espana MAG;Saenz EC;Orduna VA;Ruiperez AC;Plazas JG;Alfonso PG;Martel IJ;Flores EG;Garrido
ML;Casado DI;.SEOM clinical guidelines for the treatment of advanced colorectal cancer.Clin Transl Oncol.2010;12(11):729-734
Martin-Broto J;Gutierrez A;Garcia-del-Muro X;Lopez-Guerrero JA;Martinez-Trufero J;de Sande LM;Lainez N;Maurel J;De Juan
A;Losa F;Andres R;Casado A;Tejido PG;Blanco R;Carles J;Bellmunt J;Gomez-Espana A;Ramos R;Martinez-Serra J;LlombartBosch A;Poveda A;.Prognostic time dependence of deletions affecting codons 557 and/or 558 of KIT gene for relapse-free
survival (RFS) in localized GIST: a Spanish Group for Sarcoma Research (GEIS) Study.Annals of oncology.2010;21(7):1552-1557
Prado PM;Borrego M;Zaluski J;Arcusa A;Munoz M;Vega JM;Mel JR;Munarriz B;Llorca C;Jara C;Alba E;Florian J;Li JF;GarciaAsenjo JA;Saez A;Rios M.Adjuvant Docetaxel for High-Risk, Node-Negative Breast Cancer.2010;363(23):2200-2210
Martinez-Trufero J;Alfaro J;Felipo F;Alvarez M;Madani J;Cebollero A;.Response to trabectedin treatment in a highly pretreated
patient with an advanced meningeal hemangiopericytoma.Anti-cancer Drug.2010;21(8):795-798
Martinez-Trufero J;Isla D;Adansa JC;Irigoyen A;Hitt R;Gil-Arnaiz I;Lambea J;Lecumberri MJ;Cruz JJ;.Phase II study of
capecitabine as palliative treatment for patients with recurrent and metastatic squamous head and neck cancer after previous
platinum-based treatment.British Journal of Cancer.2010;102(12):1687-1691
Maurel J;Martins AS;Poveda A;Lopez-Guerrero JA;Cubedo R;Casado A;Martinez-Trufero J;Ayuso JR;Lopez-Pousa A;GarciaAlbeniz X;del Muro XG;de Alava E;.Imatinib Plus Low-Dose Doxorubicin in Patients With Advanced Gastrointestinal Stromal
Tumors

Refractory

to

High-Dose

Imatinib

A

Phase

I-II

Study

by

the

Spanish

Group

for

Research

on

Sarcomas.Cancer.2010;116(15):3692-3701
Milne RL;Osorio A;Cajal TRY;Baiget M;Lasa A;az-Rubio E;de la Hoya M;Caldes T;Teule A;Lazaro C;Blanco I;Balmana
J;Sanchez-Olle G;Vega A;Blanco A;Chirivella I;Cardenosa EE;Duran M;Velasco E;de Duenas EM;Tejada MI;Miramar MD;Calvo
MT;Guillen-Ponce C;Salazar.Parity and the risk of breast and ovarian cancer in BRCA1 and BRCA2 mutation carriers.Breast
cancer research and treatment.2010;119(1):221-232
Provencio M;de Las Penas R;Camps C;Artal A;Massuti B;Cobo M;Perez FJ;Sanchez A;Rosell R;.Cisplatin plus vinorelbine as
first-line treatment for advanced non-small-cell lung cancer: Is a hemogram on day 8 essential?.Lung Cancer.2010;68(3):415-419
Puente J;Lopez-Tarruella S;Ruiz A;Lluch A;Pastor M;Alba E;de la Haba J;Ramos M;Cirera L;Anton A;Llombart A;Plazaola
A;Fernandez-Aramburo A;Sastre J;az-Rubio E;Martin M;.Practical prognostic index for patients with metastatic recurrent breast
cancer: retrospective analysis of 2,322 patients from the GEICAM Spanish El Alamo Register.Breast Cancer research and
treatment. 2010;122(2):591-600

37

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