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ID Wellness
           December 3, 2010


Sharon M. Weinstein, MS, RN, CRNI®, FACW, FAAN
   Discuss incidence of Diabesity and
    pandemic nature
   State healthcare projections and cost
    factors associated with disease
   Identify key dietary and pharmacological
    factors in managing disease process
   Describe US and European approaches to
    management
An Epidemic

• U.S. newborn today has a 1 in
  3 chance of developing
  diabetes
• For Hispanics and African-
  Americans, the risk is 1 in 2

            Centers for Disease Control and Prevention (CDC)
   A term coined by former US Surgeon General
    C. Everett Koop
   Raises awareness of the health effects of
    obesity
   Diabesity® is a registered trademark of Shape
    Up America! (www.shapeup.org)
   Provides interactive information and guidance
    on weight management, healthy eating,
    physical activity, childhood obesity and other
    topics related to the prevention and
    treatment of obesity
   Is the terror within; left unchecked, could
    have a greater impact than 9/11
              Dr. Richard Carmona (former surgeon general)
   Overweight kids become overweight adults
   Robert Wood Johnson Foundation –
    spending at least $500 million over the
    next 5 years to reduce childhood obesity
   Incidence of diabetes: 800,000 cases/year
   Prevalence of diabetes: 16 million total
    (includes ~ 8 million undiagnosed)
   Number will double or triple by 2050 (1 in 3
    adults)
   $ 44 billion direct medical costs
   $ 138 billion in direct and indirect costs
   Medical costs are 3-8x higher for
    Diabetic vs. non-Diabetic
   In patient hospital costs are 5 – 9x higher
    ($7153 vs. $1222)
   60 –65% high blood pressure
   Leading cause of blindness
   Common cause of ESRD
   50% reduction in sick days and no comp
    cases between 1997 and 2003
   Expanded program to asthma and
    hypertension
   Midwest Business Group on Health (Pactiv,
    City of Naperville, Jewish Federation of
    Chicago)
   Rolled out in Milwaukee, Pittsburgh and Los
    Angeles
   Payment for medications and consultation
   Valued at $2000 per year/employee
   Usually diagnosed in children and young
    adults
   Previously known as juvenile diabetes
   The body does not produce insulin
   Either the body does not produce enough
    insulin or the cells ignore the insulin
   When glucose builds up in the blood
    instead of going into cells…
    - your cells may be starved for energy
    - high blood glucose levels affect vital
    organs
   Emergence in children is one of the obesity
    epidemic’s most eye-opening symptoms
   The terms ―overweight‖ and ―obese‖ have
    precise meanings within medicine - tied to
    a person’s Body Mass Index score
   Determined by dividing a person’s weight
    by the square of his or her height, then
    multiplying that number by 703.
   Scores between 25 and 29 are ―overweight,‖
    while those with scores 30 and above are
    ―obese‖
   Depends on administrative data
       Health risk appraisal (HRA)
       Lab
       Pharmacy
       Claims

Yields only 15% of high risk cohort
   Physician engagement
   Practice level reports
   Dietary and pharmacological factors
   Peer comparisons
   Performance-based incentives
   Moving toward real-time reporting
   Promoting utilization of services
   Better patient compliance
   Improved outcomes
   A Disease Management Approach targets
    each co-morbidity and takes a proactive
    approach to prevention and education to
    patients and physicians
   Promotes a disease management approach
   Identifying other co-morbidities present in
    this same population, such as eye, heart,
    kidney and clinical depression
   Identification of these complications
    enhances outcomes and patients are
    encouraged to utilize alternative methods
    of dealing with possible neuropathies
   Implementation of a screening program
    expands the population base from the 10%
    of diabetics that have wounds to 100% of
    the population who may be candidates for
    ulcers and other lower extremity
    complications
 Retinopathy
 Renal
 Cardiovascular
 Lower extremity
 Clinical Depression
 Hg A1c
 Blood pressure
   Safety related
   Disease control
   Health promotion
   Higher levels of self-care
Diabetic Nephropathy
40% of new cases of end-
  stage renal disease (ESRD) are        Incidence of ESRD
  attributed to diabetes              Resulting from Primary
                                          Diseases (1998)
In 2001, 41,312 people with
  diabetes began ESRD                19%
  treatment
In 2001, it cost $22.8 billion in   3%
                                                             43%

 public and private funds to         12%
 treat patients with kidney
 failure
                                           23%    Diabetes
Minorities experience higher                     Hypertension

 than average rates of                            Glomerulonephritis

 nephropathy and kidney                           Cystic Kidney

 disease                                          Other Causes
• The most common cause of new
cases of blindness among adults 20-
74 years of age
• Between 12,000 to 24,000 people
lose their sight because of diabetes
annually
• Nearly all patients with type 1
diabetes and over 60% of patients
with type 2 diabetes have retinopathy
in first 20 years of disease
Diabetes




Cardiovascular     Renal Disease    Eye Disease   Lower Extremity   Depression
                                                     Disease


Angina, MI,CABG,                                                     Poor Self-
                      Dialysis       Blindness       Amputation
  Angioplasty                                                          Care
   Abdominal obesity (excessive fat tissue in
    and around the abdomen)
   Atherogenic dyslipidemia (blood fat
    disorders — high triglycerides, low HDL
    cholesterol and high LDL cholesterol —
    that foster plaque buildups in artery
    walls)
   Elevated blood pressure
   Insulin resistance or glucose intolerance
    (the body can’t properly use insulin or
    blood sugar)
   Prothrombotic state (e.g., high fibrinogen or
    plasminogen activator inhibitor–1 in the
    blood)
   Proinflammatory state (e.g., elevated C-
    reactive protein in the blood)
   Elevated waist circumference:
    Men — Equal to or greater than 40 inches
    (102 cm)
    Women — Equal to or greater than 35 inches
    (88 cm)
   Elevated triglycerides:
    Equal to or greater than 150 mg/dL
   Reduced HDL (―good‖) cholesterol:
    Men — Less than 40 mg/dL
    Women — Less than 50 mg/dL
   Elevated blood pressure:
    Equal to or greater than 130/85 mm Hg
   Elevated fasting glucose:
    Equal to or greater than 100 mg/dL
   Weight loss to achieve a desirable weight
    (BMI less than 25 kg/m2)
   Increased physical activity, with a goal of at
    least 30 minutes of moderate-intensity
    activity on most days of the week
   Healthy eating habits that include reduced
    intake of saturated fat, trans fat and
    cholesterol
17  X more likely to develop for gangrene
30 X more likely to require amputation
2nd amputation likely to occur within 2 yrs of
first
Within 5 years 50% will die
   75% readmitted
   5-9% will die while hospitalized
   19% require nursing home placement
   Electric scooter $2000-$5000
   BK prosthesis $2000-$7000/yr
   Cost = $10 billion /yr or 20% of total
    diabetes cost
   Peripheral Vascular Disease
   Peripheral Neuropathy
   Great American diet
   Nutritional goals
   Improving metabolic function
   Glucose disposal
   Current pharmaceuticals
   Effect on kidney function
   Sulphonylureas stimulate insulin secretion
   Metformin and troglitazone increase
    glucose disposal and decrease hepatic
    glucose output without causing
    hypoglycemia
   Medical management generally improves
    blood glucose regulation in Type 2 diabetes
    patients
   Evidence base
   Smoking, drinking, overeating
   Shape Up America
   Neurocircuitry of weight control
   Common and often disabling
    complication of diabetes
    mellitus
     Impaired sensation or
      pain in the feet or hands
   Conduction is required for nervous system
    function
   Weintraub study
    - Annals of Rehabilitation Medicine, April 2003
   Weintraub study
    - Objective: to determine if constant
    wearing of multipolar static magnetic
    insoles can reduce neuropathic pain
    and quality of life scores in
    symptomatic diabetic peripheral
    neuropathy (DPN)
    -
Design: randomized, placebo-controlled
 parallel study
 - Setting: 48 centers in 27 states
 - Participants: 375 subjects with DPN state II
 or III randomly assigned to wear insoles for 4
 months; placebo group wore a similar,
 unmagnetized device
   Intervention: nerve conduction and or
    quantified sensory testing performed
    serially
   Outcome Measures:
    - Daily visual analog scale scores for
    numbness or tingling/burning and QOL
    issues tabulated over 4 months
    - Secondary measures included nerve
    conduction changes, role of placebo and
    safety issues
   Statistically significant reductions, during
    the 3rd and 4th months in burning (mean
    change for magnet treatment -12
    %; for sham -3%;P < .05)
   Numbness and tingling (magnet -10%;
    sham + 1%; P <.05)
   Exercise-induced foot pain (magnet, -12%;
    sham -4%; P<.05)
   Screen and assess the diabetic
    population for lower extremity disease
    that may lead to complications
    causing multiple hospitalizations,
    multiple surgeries, and ultimately
    amputation
   High percentage of population screened
   Reduction in lower extremity amputations
   Reduction in hospital admissions
   Reduction in hospital length of stay
   Identifying high-risk patients before the first
    acute event, then using a primary prevention
    methodology to prevent the first acute event,
    results in a significant reduction of human
    suffering.
   A collaborative approach to disease
    management, using all healthcare disciplines
    as well as patient and family, results in
    quality outcomes.
 Diabesityknows no borders…that
 is why we all need to be a part of
 the solution!
sharonw@corelimited.com
    www.corelimited.com
      www.gedinfp.com
     www.ihfglobal.com
www.mynikken.net/corewellness

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Diabesity with Sharon Weinstein

  • 1. ID Wellness December 3, 2010 Sharon M. Weinstein, MS, RN, CRNI®, FACW, FAAN
  • 2. Discuss incidence of Diabesity and pandemic nature  State healthcare projections and cost factors associated with disease  Identify key dietary and pharmacological factors in managing disease process  Describe US and European approaches to management
  • 3. An Epidemic • U.S. newborn today has a 1 in 3 chance of developing diabetes • For Hispanics and African- Americans, the risk is 1 in 2 Centers for Disease Control and Prevention (CDC)
  • 4. A term coined by former US Surgeon General C. Everett Koop  Raises awareness of the health effects of obesity  Diabesity® is a registered trademark of Shape Up America! (www.shapeup.org)
  • 5. Provides interactive information and guidance on weight management, healthy eating, physical activity, childhood obesity and other topics related to the prevention and treatment of obesity
  • 6. Is the terror within; left unchecked, could have a greater impact than 9/11 Dr. Richard Carmona (former surgeon general)  Overweight kids become overweight adults  Robert Wood Johnson Foundation – spending at least $500 million over the next 5 years to reduce childhood obesity
  • 7. Incidence of diabetes: 800,000 cases/year  Prevalence of diabetes: 16 million total (includes ~ 8 million undiagnosed)  Number will double or triple by 2050 (1 in 3 adults)
  • 8. $ 44 billion direct medical costs  $ 138 billion in direct and indirect costs  Medical costs are 3-8x higher for Diabetic vs. non-Diabetic  In patient hospital costs are 5 – 9x higher ($7153 vs. $1222)  60 –65% high blood pressure  Leading cause of blindness  Common cause of ESRD
  • 9. 50% reduction in sick days and no comp cases between 1997 and 2003  Expanded program to asthma and hypertension
  • 10. Midwest Business Group on Health (Pactiv, City of Naperville, Jewish Federation of Chicago)  Rolled out in Milwaukee, Pittsburgh and Los Angeles  Payment for medications and consultation  Valued at $2000 per year/employee
  • 11. Usually diagnosed in children and young adults  Previously known as juvenile diabetes  The body does not produce insulin
  • 12. Either the body does not produce enough insulin or the cells ignore the insulin  When glucose builds up in the blood instead of going into cells… - your cells may be starved for energy - high blood glucose levels affect vital organs
  • 13. Emergence in children is one of the obesity epidemic’s most eye-opening symptoms
  • 14. The terms ―overweight‖ and ―obese‖ have precise meanings within medicine - tied to a person’s Body Mass Index score  Determined by dividing a person’s weight by the square of his or her height, then multiplying that number by 703.  Scores between 25 and 29 are ―overweight,‖ while those with scores 30 and above are ―obese‖
  • 15. Depends on administrative data  Health risk appraisal (HRA)  Lab  Pharmacy  Claims Yields only 15% of high risk cohort
  • 16. Physician engagement  Practice level reports  Dietary and pharmacological factors  Peer comparisons  Performance-based incentives  Moving toward real-time reporting
  • 17. Promoting utilization of services  Better patient compliance  Improved outcomes
  • 18. A Disease Management Approach targets each co-morbidity and takes a proactive approach to prevention and education to patients and physicians
  • 19. Promotes a disease management approach  Identifying other co-morbidities present in this same population, such as eye, heart, kidney and clinical depression
  • 20. Identification of these complications enhances outcomes and patients are encouraged to utilize alternative methods of dealing with possible neuropathies  Implementation of a screening program expands the population base from the 10% of diabetics that have wounds to 100% of the population who may be candidates for ulcers and other lower extremity complications
  • 21.  Retinopathy  Renal  Cardiovascular  Lower extremity  Clinical Depression  Hg A1c  Blood pressure
  • 22. Safety related  Disease control  Health promotion  Higher levels of self-care
  • 23. Diabetic Nephropathy 40% of new cases of end- stage renal disease (ESRD) are Incidence of ESRD attributed to diabetes Resulting from Primary Diseases (1998) In 2001, 41,312 people with diabetes began ESRD 19% treatment In 2001, it cost $22.8 billion in 3% 43% public and private funds to 12% treat patients with kidney failure 23% Diabetes Minorities experience higher Hypertension than average rates of Glomerulonephritis nephropathy and kidney Cystic Kidney disease Other Causes
  • 24. • The most common cause of new cases of blindness among adults 20- 74 years of age • Between 12,000 to 24,000 people lose their sight because of diabetes annually • Nearly all patients with type 1 diabetes and over 60% of patients with type 2 diabetes have retinopathy in first 20 years of disease
  • 25. Diabetes Cardiovascular Renal Disease Eye Disease Lower Extremity Depression Disease Angina, MI,CABG, Poor Self- Dialysis Blindness Amputation Angioplasty Care
  • 26. Abdominal obesity (excessive fat tissue in and around the abdomen)  Atherogenic dyslipidemia (blood fat disorders — high triglycerides, low HDL cholesterol and high LDL cholesterol — that foster plaque buildups in artery walls)  Elevated blood pressure
  • 27. Insulin resistance or glucose intolerance (the body can’t properly use insulin or blood sugar)  Prothrombotic state (e.g., high fibrinogen or plasminogen activator inhibitor–1 in the blood)  Proinflammatory state (e.g., elevated C- reactive protein in the blood)
  • 28. Elevated waist circumference: Men — Equal to or greater than 40 inches (102 cm) Women — Equal to or greater than 35 inches (88 cm)  Elevated triglycerides: Equal to or greater than 150 mg/dL
  • 29. Reduced HDL (―good‖) cholesterol: Men — Less than 40 mg/dL Women — Less than 50 mg/dL  Elevated blood pressure: Equal to or greater than 130/85 mm Hg  Elevated fasting glucose: Equal to or greater than 100 mg/dL
  • 30. Weight loss to achieve a desirable weight (BMI less than 25 kg/m2)  Increased physical activity, with a goal of at least 30 minutes of moderate-intensity activity on most days of the week  Healthy eating habits that include reduced intake of saturated fat, trans fat and cholesterol
  • 31. 17 X more likely to develop for gangrene 30 X more likely to require amputation 2nd amputation likely to occur within 2 yrs of first Within 5 years 50% will die
  • 32. 75% readmitted  5-9% will die while hospitalized  19% require nursing home placement  Electric scooter $2000-$5000  BK prosthesis $2000-$7000/yr  Cost = $10 billion /yr or 20% of total diabetes cost
  • 33.
  • 34.
  • 35. Peripheral Vascular Disease  Peripheral Neuropathy
  • 36. Great American diet  Nutritional goals  Improving metabolic function
  • 37. Glucose disposal  Current pharmaceuticals  Effect on kidney function
  • 38. Sulphonylureas stimulate insulin secretion  Metformin and troglitazone increase glucose disposal and decrease hepatic glucose output without causing hypoglycemia  Medical management generally improves blood glucose regulation in Type 2 diabetes patients
  • 39. Evidence base  Smoking, drinking, overeating  Shape Up America  Neurocircuitry of weight control
  • 40. Common and often disabling complication of diabetes mellitus Impaired sensation or pain in the feet or hands
  • 41. Conduction is required for nervous system function
  • 42. Weintraub study - Annals of Rehabilitation Medicine, April 2003
  • 43. Weintraub study - Objective: to determine if constant wearing of multipolar static magnetic insoles can reduce neuropathic pain and quality of life scores in symptomatic diabetic peripheral neuropathy (DPN) -
  • 44. Design: randomized, placebo-controlled parallel study - Setting: 48 centers in 27 states - Participants: 375 subjects with DPN state II or III randomly assigned to wear insoles for 4 months; placebo group wore a similar, unmagnetized device
  • 45. Intervention: nerve conduction and or quantified sensory testing performed serially  Outcome Measures: - Daily visual analog scale scores for numbness or tingling/burning and QOL issues tabulated over 4 months - Secondary measures included nerve conduction changes, role of placebo and safety issues
  • 46. Statistically significant reductions, during the 3rd and 4th months in burning (mean change for magnet treatment -12 %; for sham -3%;P < .05)  Numbness and tingling (magnet -10%; sham + 1%; P <.05)  Exercise-induced foot pain (magnet, -12%; sham -4%; P<.05)
  • 47. Screen and assess the diabetic population for lower extremity disease that may lead to complications causing multiple hospitalizations, multiple surgeries, and ultimately amputation
  • 48. High percentage of population screened  Reduction in lower extremity amputations  Reduction in hospital admissions  Reduction in hospital length of stay
  • 49. Identifying high-risk patients before the first acute event, then using a primary prevention methodology to prevent the first acute event, results in a significant reduction of human suffering.
  • 50. A collaborative approach to disease management, using all healthcare disciplines as well as patient and family, results in quality outcomes.
  • 51.  Diabesityknows no borders…that is why we all need to be a part of the solution!
  • 52. sharonw@corelimited.com www.corelimited.com www.gedinfp.com www.ihfglobal.com www.mynikken.net/corewellness