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Diabetic disease[1]
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Diabetes mellitus (DM) is a common, chronic, metabolic syndrome characterized by hyperglycemia as a cardinal biochemical feature. The major forms of diabetes are classified according to those caused by deficiency of insulin secretion due to pancreatic β-cell damage (type 1 DM, or T1DM) and those that are a consequence of insulin resistance occurring at the level of skeletal muscle, liver, and adipose tissue, with various degrees of β-cell impairment (type 2 DM, or T2DM). T1DM is the most common endocrine-metabolic disorder of childhood and adolescence, with important consequences for physical and emotional development. Individuals with T1DM confront serious lifestyle alterations that include an absolute daily requirement for exogenous insulin, the need to monitor their own glucose level, and the need to pay attention to dietary intake. Morbidity and mortality stem from acute metabolic derangements and from long-term complications (usually in adulthood) that affect small and large vessels resulting in retinopathy, nephropathy, neuropathy, ischemic heart disease, and arterial obstruction with gangrene of the extremities. The acute clinical manifestations are due to hypoinsulinemic hyperglycemic ketoacidosis. Autoimmune mechanisms are factors in the genesis of T1DM; the long-term complications are related to metabolic disturbances (hyperglycemia). Type 1 Diabetes Mellitus Formerly called insulin-dependent diabetes mellitus (IDDM) or juvenile diabetes, T1DM is characterized by low or absent levels of endogenously produced insulin and dependence on exogenous insulin to prevent development of ketoacidosis, an acute life-threatening complication of T1DM. The natural history includes 4 distinct stages: (1) preclinical β-cell autoimmunity with progressive defect of insulin secretion, (2) onset of clinical diabetes, (3) transient remission “honeymoon period,” and (4) established diabetes associated with acute and chronic complications and decreased life expectancy. The onset occurs predominantly in childhood, with median age of 7-15 yr, but it may present at any age. The incidence of T1DM has steadily increased in many parts of the world, including Europe and the USA. T1DM is characterized by autoimmune destruction of pancreatic islet β cells. Both genetic susceptibility and environmental factors contribute to the pathogenesis. Susceptibility to T1DM is genetically controlled by alleles of the major histocompatibility complex (MHC) class II genes expressing human leukocyte antigens (HLAs). It is also associated with autoantibodies to islet cell cytoplasm (ICA), insulin (IAA), antibodies to glutamic acid decarboxylase (GADA or GAD65), and ICA512 (IA2). T1DM is associated with other autoimmune diseases such as thyroiditis, celiac disease, multiple sclerosis, and Addison disease. There is some suggestion that high dietary intake of omega-3 polyunsaturated fatty acids and vitamin D supplementation in early childhood decreases the incidence of autoi
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Marketing an optometric practice
Marketing an optometric practice
Mba monograph13 0412_marketinganoptometricpractice
Mba monograph13 0412_marketinganoptometricpractice
Presbyopia
Presbyopia
Goldman applanation tonometry
Goldman applanation tonometry
Myopia
Myopia
keratometry
keratometry
Funduscopy
Funduscopy
Optometry, a focus on vision
Optometry, a focus on vision
Astigmatism 2
Astigmatism 2
Spectacle prescription fulfillment in medical optometry cope approved
Spectacle prescription fulfillment in medical optometry cope approved
Non surgical management of strabismus .ppt
Non surgical management of strabismus .ppt
Biometry
Biometry
Contact Lens-Induced Acute Red Eye(CLARE)
Contact Lens-Induced Acute Red Eye(CLARE)
Primetry
Primetry
Blepharitis
Blepharitis
Amblyopia treatment dr mirzajani
Amblyopia treatment dr mirzajani
optometric prescription
optometric prescription
Peripheral refraction in myopia
Peripheral refraction in myopia
Intermittent exotropia
Intermittent exotropia
Auto perimetry
Auto perimetry
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Blood group antibodies different reaction grades test material required for antibody identification procedure antibody screening using 2-3 cell panel antibpdy identification using 11 cell panel immediate spin phase 37 degree c ahg phase check cells interpretation antibody workups enzyme technique
Case presentation on Antibody screening- how to solve 3 cell and 11 cell panel?
Case presentation on Antibody screening- how to solve 3 cell and 11 cell panel?
DrShinyKajal
Dermatomes and myotomes and their map and test
Dermatome and myotome test & pathology.pdf
Dermatome and myotome test & pathology.pdf
niloofarbarzegari76
SEMESTER- V CHILD HEALTH NURSING-I Modern child care emphasizes a holistic approach, nurturing a child's physical, emotional, social, and cognitive development. Shifting from a disease-centered model, modern child care prioritizes preventive care and fostering healthy growth in children. The modern concept of child care recognizes the family as a crucial partner, advocating for family-centered care that addresses individual needs. Incorporating play, proper nutrition, and a safe environment, modern child care fosters optimal child development in all domains. Modern child care empowers nurses to act as advocates, educators, and caregivers, ensuring the well-being of children at every stage.
SEMESTER-V CHILD HEALTH NURSING-UNIT-1-INTRODUCTION.pdf
SEMESTER-V CHILD HEALTH NURSING-UNIT-1-INTRODUCTION.pdf
Sachin Sharma
Co-Chairs and Presenter Marianne Davies, DNP, ACNP, AOCNP, FAAN, Beth Sandy, MSN, CRNP, FAPO, and Matthew A. Gubens, MD, MS, FASCO, prepared useful Practice Aids pertaining to NSCLC for this CME/MOC/NCPD/ILNA/IPCE activity titled “Making Patient-Centric Immunotherapy a Reality in Lung Cancer: Best Practices for Patient Education, irAE Management, and Survivorship Care.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/ILNA/IPCE information, and to apply for credit, please visit us at https://bit.ly/3RDokbZ. CME/MOC/NCPD/ILNA/IPCE credit will be available until May 24, 2025.
Making Patient-Centric Immunotherapy a Reality in Lung Cancer: Best Practices...
Making Patient-Centric Immunotherapy a Reality in Lung Cancer: Best Practices...
PVI, PeerView Institute for Medical Education
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Explore the innovative world of Video Capsule Endoscopy (VCE) and its applications in pediatric care. This SlideShare presentation covers the procedure, benefits, and considerations for using VCE in children. Learn how this non-invasive diagnostic tool is revolutionizing the detection and treatment of gastrointestinal conditions in young patients, offering a safer and more comfortable alternative to traditional methods.
Video capsule endoscopy (VCE ) in children
Video capsule endoscopy (VCE ) in children
Raju678948
world hypertension day 17th may 2024
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World Hypertension Day 17th may 2024 ppt
desktoppc
The flipchart has been developed by the Cancer Institute NSW as a tool to assist in providing information on cervical cancer and cervical screening to women of a Vietnamese background, particularly those eligible to participate in the National Cervical Screening Program (NCSP).
Cervical screening – taking care of your health flipchart (Vietnamese)
Cervical screening – taking care of your health flipchart (Vietnamese)
Cancer Institute NSW
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Unlocking Holistic Wellness: Addressing Depression, Mental Well-Being, and St...
Unlocking Holistic Wellness: Addressing Depression, Mental Well-Being, and St...
Health Kinesiology Natural Bioenergetics
Integrated Neuromuscular Inhibition technique is Manual Physiotherapy Technique used for Acute and Chronic Pain, Sports Condition, Spasm, for Trigger Point and Tender point release, for weaker muscle, to strengthen muscle, to realease tightness of muscle, . this includes Muscle energy technique, Positional Release Technique/ srain-counterstrain and Ischemic Contraction.
Integrated Neuromuscular Inhibition Technique (INIT)
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Renal Replacement Therapy in Acute Kidney Injury -time and modality -Dr Ayman Seddik
Renal Replacement Therapy in Acute Kidney Injury -time modality -Dr Ayman Se...
Renal Replacement Therapy in Acute Kidney Injury -time modality -Dr Ayman Se...
Ayman Seddik
Presented at the Annual Scientific Sessions of the Heart Rhythm Society, Boston, USA, May 2024 History of the development of the concept and many ECG examples
A thorough review of supernormal conduction.pptx
A thorough review of supernormal conduction.pptx
Sergio Pinski
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A rare case of double-diverticulae of the Gallbladder found during a routine elective cholecystectomy is presented including intra operative and specimen images.
Gallbladder Double-Diverticular: A Case Report المرارة مزدوجة التج: تقرير حالة
Gallbladder Double-Diverticular: A Case Report المرارة مزدوجة التج: تقرير حالة
Mohamad محمد Al-Gailani الكيلاني
Tips and tricks to pass the cardiovascular station for PACES exam
Tips and tricks to pass the cardiovascular station for PACES exam
Tips and tricks to pass the cardiovascular station for PACES exam
Junhao Koh
Making treatment decisions is stressful. The work of understanding complex medical information, crafting questions for your medical team, and trusting oneself is hard. We break down this intense time in ways that might feel more manageable and help you regain a sense of calm as you work hard to care for yourself at each turn in the road. Let’s talk about it.
Let's Talk About It: Ovarian Cancer (The Emotional Toll of Treatment Decision...
Let's Talk About It: Ovarian Cancer (The Emotional Toll of Treatment Decision...
bkling
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Case presentation on Antibody screening- how to solve 3 cell and 11 cell panel?
Case presentation on Antibody screening- how to solve 3 cell and 11 cell panel?
Dermatome and myotome test & pathology.pdf
Dermatome and myotome test & pathology.pdf
SEMESTER-V CHILD HEALTH NURSING-UNIT-1-INTRODUCTION.pdf
SEMESTER-V CHILD HEALTH NURSING-UNIT-1-INTRODUCTION.pdf
Making Patient-Centric Immunotherapy a Reality in Lung Cancer: Best Practices...
Making Patient-Centric Immunotherapy a Reality in Lung Cancer: Best Practices...
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5cladba raw material 5CL-ADB-A precursor raw
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Video capsule endoscopy (VCE ) in children
Video capsule endoscopy (VCE ) in children
World Hypertension Day 17th may 2024 ppt
World Hypertension Day 17th may 2024 ppt
Cervical screening – taking care of your health flipchart (Vietnamese)
Cervical screening – taking care of your health flipchart (Vietnamese)
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Unlocking Holistic Wellness: Addressing Depression, Mental Well-Being, and St...
Unlocking Holistic Wellness: Addressing Depression, Mental Well-Being, and St...
Integrated Neuromuscular Inhibition Technique (INIT)
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Renal Replacement Therapy in Acute Kidney Injury -time modality -Dr Ayman Se...
Renal Replacement Therapy in Acute Kidney Injury -time modality -Dr Ayman Se...
A thorough review of supernormal conduction.pptx
A thorough review of supernormal conduction.pptx
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Gallbladder Double-Diverticular: A Case Report المرارة مزدوجة التج: تقرير حالة
Gallbladder Double-Diverticular: A Case Report المرارة مزدوجة التج: تقرير حالة
Tips and tricks to pass the cardiovascular station for PACES exam
Tips and tricks to pass the cardiovascular station for PACES exam
Let's Talk About It: Ovarian Cancer (The Emotional Toll of Treatment Decision...
Let's Talk About It: Ovarian Cancer (The Emotional Toll of Treatment Decision...
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Fluorescein angiography procedure
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