Ist scientific possibilities_200911_web-2

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Technologie Gesundheit & Medizin

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
MediSapiens Oy
Scientiﬁc possibilities of IST database
20. September 2011

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
Stratify your patients with
thousands of others
Genomic signature for chromosomal instability
Hundredsofpatients
High
Medium
Low
Data from
your patiens?
Worst prognosis?
Resistant for therapy?
Best prognosis?

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
New therapy target for Ewing’s sarcoma?

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
Novel breast cancer associated gene
Only three publications in PubMed
(none brca associated)

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
High ectopic expression
in variety of cancers

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
Key EMT regulator and
miRNA target in Brca

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
Nearly unknown MMP related gene

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
Known cell cycle player – new target
for Burkitt’s lymphoma therapy?

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
Signiﬁcant subsets of patients in multiple cancers
for a known phosphatase downstream of KRAS

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
We have a patent
pending algorithm*
that enables you to
compare your samples
with over 15 000 fully
annotated cancer
samples.
Here we see three
commonly used
melanoma cell lines,
and how their gene
expression matches
actual in vivo samples,
with regards to
melanoma speciﬁc
genes.
* Kilpinen et al. BioData Mining 2011, 4:5 Ojala et. al. Genome Medicine, In Press
Are you sure your model actually
models the cancer you study?

Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com
IST Online

Copyright © 2011 MediSapiens Ltd. All rights reserved. • www.medisapiens.com
MediSapiens Ltd.
Biomedicum Helsinki
Tukholmankatu 8A
FIN-00290 Helsinki
+358 50 363 1848
contact@medisapiens.com
medisapiens.com

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Ist scientific possibilities_200911_web-2

2. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com Stratify your patients with thousands of others Genomic signature for chromosomal instability Hundredsofpatients High Medium Low Data from your patiens? Worst prognosis? Resistant for therapy? Best prognosis?

10. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com We have a patent pending algorithm* that enables you to compare your samples with over 15 000 fully annotated cancer samples. Here we see three commonly used melanoma cell lines, and how their gene expression matches actual in vivo samples, with regards to melanoma speciﬁc genes. * Kilpinen et al. BioData Mining 2011, 4:5 Ojala et. al. Genome Medicine, In Press Are you sure your model actually models the cancer you study?

12. Copyright © 2011 MediSapiens Ltd. All rights reserved. • www.medisapiens.com MediSapiens Ltd. Biomedicum Helsinki Tukholmankatu 8A FIN-00290 Helsinki +358 50 363 1848 contact@medisapiens.com medisapiens.com