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Enhancing SLAP Repairs with Fibrin-PRP Clots
                                                    Alan M Hirahara MD               FRCSC1,         Kyle Yamashiro                          PT2,        Russell Dunning                           MPT 2
                                                                       1 - Private Practice, Sacramento, CA / 2 - Results Physical Therapy, Sacramento, CA



INTRODUCTION                                                                                          PATIENT DEMOGRAPHICS
• In the literature, 20% non-healing of SLAP repairs reported [1].                                           Control Group                                                                 Study Group
• Fibrin clots – Improved healing with meniscal repairs but technically                                  •                  39 patients                                                •           139 patients
  challenging with arthroscopy [2].                                                                      •                  23 male (59%), 16 female                                   •           85 male (61%), 54 female
                                                                                                         •                  Age range: 18 – 66 years                                   •           Age range: 13 – 77 years
• Platelet-Rich Plasma (PRP) – Improved healing of soft tissues & bone [3].                              •                  Age average: 43.09 years
                                                                                                                                                                                       •           Age average: 45.80 years

STUDY DESIGN
                                                                                                      STUDY RESULTS
• Case-Control analysis of 180 patients, collected 1/07 – 12/08
• Same surgeon, same therapy group                                                                                                        Pain Scores                                                                                                ASES Scores

• Inclusions: All SLAP repairs / Exclusions: Any post-op trauma
                                                                                                                      p = NS        p = NS           p < 0.001         p < 0.05                                                   p = NS          p < 0.05           p < 0.001           p = 0.06
                                                                                                                             7.1                                                                                                                                                                   81.9
                                                                                                             8.0    7.1                                                                                                    90.0
                                                                                                                                                                                                                                                                                          72.7

• Failure to heal: Evaluated any symptoms 4-6 months post-op with repeat MRA
                                                                                                                                                                                                                                                                                  71.0
                                                                                                                                                                                                                           80.0
                                                                                                             7.0                    6.0

                                                                                                                                             5.2                                                                           70.0
                                                                                                             6.0                                                                                                                                                       56.3


  or surgery
                                                                                                                                                       4.8
                                                                                                                                                                                                                           60.0
                                                                                                             5.0                                                                                                                                             45.2
                                                                                                                                                                                                                                           43.1
                                                                                                                                                                                                                           50.0
                                                                                                                                                                                                                                  35.9              36.9
                                                                                                             4.0                                                 3.0    3.1
                                                                                                                                                                                                                           40.0
                                                                                                             3.0
                                                                                                                                                                                 1.7                                       30.0



APPLICATION OF FIBRIN-PRP CLOT
                                                                                                             2.0
                                                                                                                                                                                                                           20.0

                                                                                                             1.0                                                                                                           10.0


                                                                                                             0.0                                                                                                            0.0

                                                                                                                   Pre-op          1 Month           3 Month           6 Month                                                    Pre-op           1 Month            3 Month            6 Month


  60 ml blood from patient pre-operatively
                                                                  Platelet Poor Plasma                                             Control Group   Study Group                                                                                      Control Group   Study Group

                                                                          (PPP)
                                                             Platelet Rich Plasma (PRP)
                                                                                                         Statistically significant:                                                                                                                        Failures
                                                             Red Blood Cells
  Blood centrifuged for 8 minutes using a
                                                                                                                                                                                                                                                                p = 0.008
                                                                                                                                                                                                                                                              p = 0.008
                                                                                                              - Improved pain scores by 3 months
      platelet concentration system*                                                                                                                                                                              12.00%                          10.26%


                                                                                                              - Improved ASES scores by 3 months                                                                  10.00%



                                                                                                                                                                                                                                                  4/39

                                                                                                              - Improved time to discharge by 94.4 days
                                                                                                                                                                                                                   8.00%




   Fibrin-PRP mixture created 3:1 ratio
                                                                                                                                                                                                                   6.00%




                                                                                                              - Improved return to work by 64.6 days                                                               4.00%


                                                                                                                                                                                                                                                                       0.72%

                                                                                                              - Improved failure rate from 10.3% to 0.7%
                                                                                                                                                                                                                   2.00%
                                                                                                                                                                                                                                                                    1/139

                                                                                                                                                                                                                   0.00%


                                                                                                                                                                                                                                                  Control Group      Study Group

    Suture anchors# placed & sutures
                passed                                                                              CONCLUSIONS
                                                                                                    • Fibrin-PRP clots enhance SLAP repairs:
        Fibrin-PRP clot placed in-situ
                                                                                                      • Reliable, Improved Healing
               arthroscopically
                                                                                                      • Fewer Revisions
                                                                                                      • Less Pain                                                                                                                 REFERENCES
                                                                                                                                                                                                                                  1. Snyder, S. J Arthroscopy & Related Surg 1990;6:274-9.
 Sutures tied with clot between glenoid &                                                             • Faster Recovery                                                                                                           2. Arnoczky, S. JBJS 1988;70:1209-17.
                  labrum                                                                                                                                                                                                          3. Marx, R. J Oral Maxfac Surgery 2004;62:489-96.
                                                                                                                                                                                                                                  * Plasmax PlusTM , Biomet Biologics
                                                                                                                                                                                                                                  # BioSutureTakTM, Arthrex

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Enhancing SLAP repairs with Fibrin-PRP clots - Poster

  • 1. Enhancing SLAP Repairs with Fibrin-PRP Clots Alan M Hirahara MD FRCSC1, Kyle Yamashiro PT2, Russell Dunning MPT 2 1 - Private Practice, Sacramento, CA / 2 - Results Physical Therapy, Sacramento, CA INTRODUCTION PATIENT DEMOGRAPHICS • In the literature, 20% non-healing of SLAP repairs reported [1]. Control Group Study Group • Fibrin clots – Improved healing with meniscal repairs but technically • 39 patients • 139 patients challenging with arthroscopy [2]. • 23 male (59%), 16 female • 85 male (61%), 54 female • Age range: 18 – 66 years • Age range: 13 – 77 years • Platelet-Rich Plasma (PRP) – Improved healing of soft tissues & bone [3]. • Age average: 43.09 years • Age average: 45.80 years STUDY DESIGN STUDY RESULTS • Case-Control analysis of 180 patients, collected 1/07 – 12/08 • Same surgeon, same therapy group Pain Scores ASES Scores • Inclusions: All SLAP repairs / Exclusions: Any post-op trauma p = NS p = NS p < 0.001 p < 0.05 p = NS p < 0.05 p < 0.001 p = 0.06 7.1 81.9 8.0 7.1 90.0 72.7 • Failure to heal: Evaluated any symptoms 4-6 months post-op with repeat MRA 71.0 80.0 7.0 6.0 5.2 70.0 6.0 56.3 or surgery 4.8 60.0 5.0 45.2 43.1 50.0 35.9 36.9 4.0 3.0 3.1 40.0 3.0 1.7 30.0 APPLICATION OF FIBRIN-PRP CLOT 2.0 20.0 1.0 10.0 0.0 0.0 Pre-op 1 Month 3 Month 6 Month Pre-op 1 Month 3 Month 6 Month 60 ml blood from patient pre-operatively Platelet Poor Plasma Control Group Study Group Control Group Study Group (PPP) Platelet Rich Plasma (PRP) Statistically significant: Failures Red Blood Cells Blood centrifuged for 8 minutes using a p = 0.008 p = 0.008 - Improved pain scores by 3 months platelet concentration system* 12.00% 10.26% - Improved ASES scores by 3 months 10.00% 4/39 - Improved time to discharge by 94.4 days 8.00% Fibrin-PRP mixture created 3:1 ratio 6.00% - Improved return to work by 64.6 days 4.00% 0.72% - Improved failure rate from 10.3% to 0.7% 2.00% 1/139 0.00% Control Group Study Group Suture anchors# placed & sutures passed CONCLUSIONS • Fibrin-PRP clots enhance SLAP repairs: Fibrin-PRP clot placed in-situ • Reliable, Improved Healing arthroscopically • Fewer Revisions • Less Pain REFERENCES 1. Snyder, S. J Arthroscopy & Related Surg 1990;6:274-9. Sutures tied with clot between glenoid & • Faster Recovery 2. Arnoczky, S. JBJS 1988;70:1209-17. labrum 3. Marx, R. J Oral Maxfac Surgery 2004;62:489-96. * Plasmax PlusTM , Biomet Biologics # BioSutureTakTM, Arthrex