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To better mimic the tissue
microenvironment and provide more
predictive tools for drug development
BIOMIMESYS®
Biofunctionalized hydroscaffold
for 3D cell culture
Biotechnology company specialized in cell imaging
which provides HCA/HCS services
BIOMIMESYS® ScaffoldDecellularized in vivo ECM
by
Product
Specifications Compositions
Elastic
modulus
BIOMIMESYS®
Liver
HA + RGDS, Galactosamine,
Collagen I, Collagen IV
0.6 kPa
BIOMIMESYS®
Adipose tissue
HA + RGDS, Collagen I,
Collagen VI
0.45 kPa
BIOMIMESYS®
Oncology
HA + Collagen I 0.4 kPa
Plate specifications:
 RGDS or Galactosamine grafted
Hyaluronic Acid
 Physiological amount of ECM
compound
 Undenatured collagen
 Elastic modulus regarding organs
Scalable hydroscaffold
in vivo like chemical composition and physicochemical
properties (porosity , Elastic modulus...)
BIOMIMESYS® hydroscaffold
Precast matrix in a 96-WELL PLATE
The only technology based on HA and ECM compound
ready to use
Cell lines
Primary cells
iPSCs
e.g. HepG2
3 – CHOOSE YOUR READ-OUTS
Hoechst ; EDU;
mitotracker; colocalization
HCT116
Proliferation, apoptosis, cell motility, Cell structure, Stress, Protein
analysis, mRNA analysis …
MRP2; Actin;
colocalization
HepG2
1 – CHOOSE YOUR CELLS & MICROENVIRONNEMENT
2 - CHOOSE YOUR INDUCERS & INCUBATION TIME
Services
ECM: Define
- Composition
- Elastic modulus
- Porosity
Perilipin (TG), nucleus
Human Preadipocytes
(HWP)
Small
Molecules
Biologicals Ingredients Starvations
UV
Radiations
Fixed
Cells
Live
Cells
BIOMIMESYS® Liver
Hoechst; Phalloidin
HepG2
BIOMIMESYS®
Adipose Tissue
BIOMIMESYS®
Oncology
Contact us for further information
www.biomimesys.com
hello@biomimesys.com
+33 769 999 137
Lille Rennes
OUR VALUES  Expertise
 Efficiency
 Flexibility
 Transparency
Robotic Platform & innovative 3D models
for HCA and HCS services
Innovative & relevant in vitro
models
Enriched information on biological
content
Phenotypic screening
Highly visual
Automated process
Multi-parametric study
Big Data / Machine learning

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BIOMIMESYS® Biofunctionalized hydroscaffold for 3D cell culture

  • 1. To better mimic the tissue microenvironment and provide more predictive tools for drug development BIOMIMESYS® Biofunctionalized hydroscaffold for 3D cell culture Biotechnology company specialized in cell imaging which provides HCA/HCS services BIOMIMESYS® ScaffoldDecellularized in vivo ECM by
  • 2. Product Specifications Compositions Elastic modulus BIOMIMESYS® Liver HA + RGDS, Galactosamine, Collagen I, Collagen IV 0.6 kPa BIOMIMESYS® Adipose tissue HA + RGDS, Collagen I, Collagen VI 0.45 kPa BIOMIMESYS® Oncology HA + Collagen I 0.4 kPa Plate specifications:  RGDS or Galactosamine grafted Hyaluronic Acid  Physiological amount of ECM compound  Undenatured collagen  Elastic modulus regarding organs Scalable hydroscaffold in vivo like chemical composition and physicochemical properties (porosity , Elastic modulus...) BIOMIMESYS® hydroscaffold Precast matrix in a 96-WELL PLATE The only technology based on HA and ECM compound ready to use
  • 3. Cell lines Primary cells iPSCs e.g. HepG2 3 – CHOOSE YOUR READ-OUTS Hoechst ; EDU; mitotracker; colocalization HCT116 Proliferation, apoptosis, cell motility, Cell structure, Stress, Protein analysis, mRNA analysis … MRP2; Actin; colocalization HepG2 1 – CHOOSE YOUR CELLS & MICROENVIRONNEMENT 2 - CHOOSE YOUR INDUCERS & INCUBATION TIME Services ECM: Define - Composition - Elastic modulus - Porosity Perilipin (TG), nucleus Human Preadipocytes (HWP) Small Molecules Biologicals Ingredients Starvations UV Radiations Fixed Cells Live Cells BIOMIMESYS® Liver Hoechst; Phalloidin HepG2 BIOMIMESYS® Adipose Tissue BIOMIMESYS® Oncology
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