Water Content of Drug? Impact Of Water Content Of Drug. Methods Of Determining Water Content Of Drug. Formula for Water Content Determination. Calculation With Lab Practical Demo. Loss On Drying of Drug? Impact Of LOD Of Drug. Formula of LOD Determination. Calculation With Lab Practical Demo. Basic Difference.

1. Difference Between Water Content Vs. Loss On
Drying Of Drug In Pharma Company Part-3

2. 1. Water Content of Drug?
2. Impact Of Water Content Of Drug.
3. Methods Of Determining Water Content Of Drug.
4. Formula for Water Content Determination.
5. Calculation With Lab Practical Demo.
6. Loss On Drying of Drug?
7. Impact Of LOD Of Drug.
8. Formula of LOD Determination.
9. Calculation With Lab Practical Demo.
10. Basic Difference.

3. Title Water Content Loss On Drying
Description
It is determine by KF titration
method & it consist of traces of
water present in sample.
In this we measure amount of
water and other volatile matters
present with sample
Sample
Stage
In-process, Final or Finished
Sample
Inprocess Samples
Sample
Physical
State
Solid or Liquid Solid mainly wet cakes like paste
Impact on
quality
Yes Yes

4. Title Water Content Loss On Drying
Method
Involves
Chemical Reaction
Drying of Sample under specific
Temp. at std duration
Depends on Quality of reagent used
Temperature
Moisture content
Humidity
Bulk density
Resistance to Airflow
Formula
= Mass of water in sample / mass of
dry sample * 100
= Mass of water in sample / Mass
of wet sample * 100