Moodle Overviewof Scd.97to2003 Revised33008

AN INHERITED DISEASE THAT AFFECTS THE RED BLOOD CELL BY TINA E. COLEMAN, MPH Overview of Sickle Cell Disease

What is sickle cell disease ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

Characteristics of sickle cell disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

How common is sickle cell disease? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

Life Expectancy ,[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

Who does sickle cell disease affect? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

What are the rates for sickle cell disease by ethnic groups? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

Are there different types of hemoglobin? ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

Are their different types of sickle cell disease ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

How do you get sickle cell disease? ,[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

How do you inherit the sickle cell gene? ,[object Object],[object Object],06/04/09 Tina E. Coleman, MPH 46 pairs of chromosomes

Genes are messengers ,[object Object],06/04/09 Tina E. Coleman, MPH  This represents a gene. A gene carries messages (DNA )

So what are genes? ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

Genes determine your hemoglobin type ,[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

How are your hemoglobin genes affected? ,[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

What is sickle cell trait? ,[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

Other things you need to know about sickle cell trait ,[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

What causes people to have medical problems ? ,[object Object],06/04/09 Tina E. Coleman, MPH

The Red Blood Cell ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

The Red Blood Cell (cont.) ,[object Object],06/04/09 Tina E. Coleman, MPH

The sickle red blood cell ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH Note the different distorted shapes of cells with sickle hemoglobin

The sickle shaped red blood cell (cont. 1) ,[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH Red blood cells clumping and sticking together is called vaso-occlusion

The sickle shaped red blood cell (cont. 2) ,[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

What will be covered in the other units? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],06/04/09 Tina E. Coleman, MPH

Moodle Overviewof Scd.97to2003 Revised33008

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